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J

Jedd D. Wolchok

Memorial Sloan Kettering Cancer Center
H指数:173
被引数:20.4万

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Tumor-intrinsic expression of signal regulatory protein α contributes to the suppression of anti-tumor immune responses

肿瘤内信号调节蛋白α的表达有助于抑制抗肿瘤免疫应答

Cell Reports
IF6.9
2026-05-290
OAAI
Chien-Huan Weng; Chana Schochet; Vincent Panneton; Anais Assouvie; Shabnam Eghbali; Sébastien Monette; Cailian Liu; Yacine Marouf; Levi Mangarin; Lucia Morgado-Palacin; Parwiz Abrahimi; Jonathan F. Khan; Christopher S. Hackett; Daniel Hua; Qianqian Lin; Linda Hamadene; Pamela M. Holland; Jedd D. Wolchok; Taha Merghoub
An ultrasmall core–shell silica nanoparticle improves antitumour immunity and survival by remodelling suppressive melanoma microenvironments

超小型核壳二氧化硅纳米颗粒通过重塑抑制性黑色素瘤微环境来提高抗肿瘤免疫力和存活率

Nature Nanotechnology
IF34.9
2025-12-290
OAAI
Gabriel De Leon; Li Zhang; Nabil A. Siddiqui; Nada Naguib; Feng Chen; Reethi Padmanabhan; Tuo Zhang; Sebastien Monette; Fabio Socciarelli; Rachel Lee; Miles Pourbaghi; Thomas P. Quinn; Michael Overholtzer; Taha Merghoub; Ulrich Wiesner; Jedd D. Wolchok; Michelle S. Bradbury
Thrombospondin-1–CD47 signaling contributes to the development of T cell exhaustion in cancer

Thrombospondin-1-CD47信号有助于癌症中T细胞耗竭的发展

Nature Immunology
IF27.6
2025-11-170
PRE
Chien-Huan Weng; Anais Assouvie; Lauren Dong; Jean-Christophe Beltra; Sadna Budhu; Levi Mangarin; Yacine Marouf; Lucia Morgado-Palacin; Cailian Liu; Sébastien Monette; Jonathan F. Khan; Isabell Schulze; Dmitriy Zamarin; Linda Hamadene; Fadi Samaan; Daniel Hirschhorn; Stephane Pourpe; David Schröder; Roberta Zappasodi; Pamela M. Holland; Niroshana Anandasabapathy; E. John Wherry; Jedd D. Wolchok; Taha Merghoub
Error-corrected flow-based sequencing at whole-genome scale and its application to circulating cell-free DNA profiling

全基因组规模的纠错型流式测序及其在循环游离DNA分析中的应用

NATURE METHODS
IF32.1
2025-04-110
PRE
Cheng, Alexandre Pellan; Widman, Adam J.; Arora, Anushri; Rusinek, Itai; Sossin, Aaron; Rajagopalan, Srinivas; Midler, Nicholas; Hooper, William F.; Murray, Rebecca M.; Halmos, Daniel; Langanay, Theophile; Chu, Hoyin; Inghirami, Giorgio; Potenski, Catherine; Germer, Soren; Marton, Melissa; Manaa, Dina; Helland, Adrienne; Furatero, Rob; Mcclintock, Jaime; Winterkorn, Lara; Steinsnyder, Zoe; Wang, Yohyoh; Alimohamed, Asrar I.; Malbari, Murtaza S.; Saxena, Ashish; Callahan, Margaret K.; Frederick, Dennie T.; Spain, Lavinia; Sigouros, Michael; Manohar, Jyothi; King, Abigail; Wilkes, David; Otilano, John; Elemento, Olivier; Mosquera, Juan Miguel; Jaimovich, Ariel; Lipson, Doron; Turajlic, Samra; Zody, Michael C.; Altorki, Nasser K.; Wolchok, Jedd D.; Postow, Michael A.; Robine, Nicolas; Faltas, Bishoy M.; Boland, Genevieve; Landau, Dan A.
Long-term outcomes among patients who respond within the first year to nivolumab plus ipilimumab or nivolumab monotherapy: A pooled analysis in 935 patients
EUROPEAN JOURNAL OF CANCER
IF7.1
2025-01-010
OAAI
Robert, C.; Long, G. V.; Larkin, J.; Wolchok, J. D.; Hassel, J. C.; Schadendorf, D.; Hodi, F. S.; Lebbe, C.; Grob, J. -j.; Hyngstrom, J. R.; Wagstaff, J.; Chesney, J.; Butler, M. O.; Bechter, O.; Marquez-Rodas, I.; Pavlick, A. C.; Durani, P.; Benito, M. Pe; Wang, P.; Postow, M. A.; Ascierto, P. A.
Concurrent SOS1 and MEK suppression inhibits signaling and growth of NF1-null melanoma

同时抑制SOS1和MEK抑制NF1-null黑色素瘤的信号传导和生长

CELL REPORTS MEDICINE
IF10.6
2024-11-010
OAAI
Marasco, Michelangelo; Kumar, Dinesh; Seale, Tessa; Borrego, Santiago Garcia; Kaplun, Esther; Aricescu, Ilinca; Cole, Soren; Qeriqi, Besnik; Qiu, Juan; Chen, Xiaoping; Bahr, Amber; Fidele, Deborah; Hofmann, Marco H.; Gerlach, Daniel; Savarese, Fabio; Merghoub, Taha; Wolchok, Jedd D.; Yao, Zhan; de Stanchina, Elisa; Solit, David; Misale, Sandra; Rosen, Neal
10-y survival outcomes from the phase III CheckMate 067 trial of nivolumab plus ipilimumab in advanced melanoma

CheckMate 067试验中，纳武利尤单抗联合伊匹木单抗治疗晚期黑色素瘤的10年生存结局

ANNALS OF ONCOLOGY
IF65.4
2024-09-012
PRE
Larkin, J.; Sileni, V. Chiarion; Marqueste, C. Gaudy; Rutkowski, P.; Medina, T. M.; Lao, C. D.; Cowey, C. L.; Schadendorf, D.; Wagstaff, J.; Dummer, R.; Queirolo, P.; Walker, J.; Butler, M. O.; Hill, A. G.; Marquez-Rodas, I.; Haanen, J. B. A. G.; Nassar, A.; Askelson, M.; Hodi, F. S.; Wolchok, J. D.
Ultrasensitive plasma-based monitoring of tumor burden using machine-learning-guided signal enrichment

使用机器学习引导的信号富集技术对基于血浆的肿瘤负荷进行超灵敏监测

NATURE MEDICINE
IF50
2024-06-144
OAAI
Widman, Adam J.; Shah, Minita; Frydendahl, Amanda; Halmos, Daniel; Khamnei, Cole C.; Ogaard, Nadia; Rajagopalan, Srinivas; Arora, Anushri; Deshpande, Aditya; Hooper, William F.; Quentin, Jean; Bass, Jake; Zhang, Mingxuan; Langanay, Theophile; Andersen, Laura; Steinsnyder, Zoe; Liao, Will; Rasmussen, Mads Heilskov; Henriksen, Tenna Vesterman; Jensen, Sarah ostrup; Nors, Jesper; Therkildsen, Christina; Sotelo, Jesus; Brand, Ryan; Schiffman, Joshua S.; Shah, Ronak H.; Cheng, Alexandre Pellan; Maher, Colleen; Spain, Lavinia; Krause, Kate; Frederick, Dennie T.; den Brok, Wendie; Lohrisch, Caroline; Shenkier, Tamara; Simmons, Christine; Villa, Diego; Mungall, Andrew J.; Moore, Richard; Zaikova, Elena; Cerda, Viviana; Kong, Esther; Lai, Daniel; Malbari, Murtaza S.; Marton, Melissa; Manaa, Dina; Winterkorn, Lara; Gelmon, Karen; Callahan, Margaret K.; Boland, Genevieve; Potenski, Catherine; Wolchok, Jedd D.; Saxena, Ashish; Turajlic, Samra; Imielinski, Marcin; Berger, Michael F.; Aparicio, Sam; Altorki, Nasser K.; Postow, Michael A.; Robine, Nicolas; Andersen, Claus Lindbjerg; Landau, Dan A.

研究方向

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T
Taha Merghoub
H 指数:93论文数:854被引数:5.2万
M
Michael A. Postow
H 指数:88论文数:659被引数:6.5万
S
Sadna Budhu
H 指数:29论文数:187被引数:4,576
M
Margaret K. Callahan
H 指数:69论文数:426被引数:5.0万
F
F. Stephen Hodi
H 指数:156论文数:1,525被引数:16.1万
A
Alan N. Houghton
H 指数:80论文数:403被引数:2.1万
C
Caroline Robert
H 指数:154论文数:1,485被引数:15.7万
C
Cailian Liu
H 指数:26论文数:145被引数:1.0万
R
Roberta Zappasodi
H 指数:36论文数:231被引数:1.5万
M
Matthew D. Hellmann
H 指数:116论文数:837被引数:9.7万