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NOTCH1 reverses immune suppression in small cell lung cancer through reactivation of STING NOTCH1通过重新激活STING逆转小细胞肺癌中的免疫抑制 Kim, Yoo Sun; Nabet, Barzin Y.; Cortez, Briana N.; Sun, Nai-Yun; Sebastian, Robin; Redon, Christophe E.; Ray, Anagh; Liu, Liang; Ishola, Afeez A.; Loew, Sarah; Dhall, Anjali; Sindiri, Sivasish; Gayevskiy, Velimir; Lee, Min-Jung; Rastogi, Shraddha; Sato, Nahoko; Kedei, Noemi; Andresson, Thorkell; Das, Sudipto; Kumar, Suresh; Bers, Alan E.; Zhang, Hongliang; Chiappori, Alberto; Gopal, Priyanka; Abazeed, Mohamed E.; Chen, Haobin; Aladjem, Mirit I.; Pommier, Yves; Velez, Moises J.; Shames, David S.; Roper, Nitin 分享 收藏
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Transfer RNA acetylation regulates in vivo mammalian stress signaling 转运RNA乙酰化调控活体内哺乳动物应激信号传导 Gamage, Supuni Thalalla; Khoogar, Roxane; Manage, Shereen Howpay; Daros, Judey T.; Crawford, McKenna C.; Georgeson, Joe; Polevoda, Bogdan V.; Sanders, Chelsea; Lee, Kendall A.; Nance, Kellie D.; Iyer, Vinithra; Kustanovich, Anatoly; Perez, Minervo; Thu, Chu T.; Nance, Sam R.; Amin, Ruhul; Miller, Christine N.; Holewinski, Ronald J.; Das, Sudipto; Meyer, Thomas J.; Koparde, Vishal; Yang, Acong; Jailwala, Parthav; Nguyen, Joe T.; Andresson, Thorkell; Gu, Shuo; Mock, Beverly A.; Edmondson, Elijah F.; Difilippantonio, Simone; Schwartz, Schraga; O'Connell, Mitchell R.; Meier, Jordan L. 分享 收藏
Metabolic dependency mapping identifies Peroxiredoxin 1 as a driver of resistance to ATM inhibition 代谢依赖性分析确定了Peroxiredoxin 1是ATM抑制的驱动因素。 Li, Haojian; Furusawa, Takashi; Cavero, Renzo; Xiao, Yunjie; Chari, Raj; Wu, Xiaolin; Sun, David; Hartmann, Oliver; Dhall, Anjali; Holewinski, Ronald; Andresson, Thorkell; Karim, Baktiar; Villamor-Paya, Marina; Gallardo, Devorah; Day, Chi-Ping; Pal, Lipika R.; Nair, Nishanth Ulhas; Ruppin, Eytan; Aladjem, Mirit I.; Pommier, Yves; Villamor-Paya, Marina; Diefenbacher, Markus E.; Lim, Jung Mi; Levine, Rodney L.; Stracker, Travis H. 分享 收藏
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Chemical tools to define and manipulate interferon-inducible Ubl protease USP18 化学工具用于定义和操纵干扰素诱导的泛素样蛋白酶USP18 Davis, Griffin J.; Omole, Anthony O.; Jung, Yejin; Rut, Wioletta; Holewinski, Ronald; Suazo, Kiall F.; Kim, Hong-Rae; Yang, Mo; Andresson, Thorkell; Drag, Marcin; Yoo, Euna 分享 收藏
TARGETING MITOCHONDRIAL PROTEASE IN DIFFUSE GLIOMAS Kim, Olga; Sergi, Zach; Yu, Guangyang; Li, Qi; Lu, Peng; Hsia, Ru-Ching; Robey, Robert; Chari, Raj; Wang, Herui; Tran, Bao; Andresson, Thorkell; Gottesman, Michael; Liu, Zhenggang; Graves, Lee; Iwanowicz, Edwin; Wu, Jing 分享 收藏
Multiplatform metabolomic interlaboratory study of a whole human stool candidate reference material from omnivore and vegan donors Cruz, Abraham Kuri; Alves, Marina Amaral; Andresson, Thorkell; Bayless, Amanda L.; Bloodsworth, Kent J.; Bowden, John A.; Bullock, Kevin; Burnet, Meagan C.; Carnevale Neto, Fausto; Choy, Angelina; Clish, Clary B.; Couvillion, Sneha P.; Cumeras, Raquel; Dailey, Lucas; Dallmann, Guido; Davis, W. Clay; Deik, Amy A.; Dickens, Alex M.; Djukovic, Danijel; Dorrestein, Pieter C.; Eder, Josie G.; Fiehn, Oliver; Flores, Roberto; Gika, Helen; Hagiwara, Kehau A.; Pham, Tuan Hai; Harynuk, James J.; Aristizabal-Henao, Juan J.; Hoyt, David W.; Jean-Francois, Focant; Krakstrom, Matilda; Kumar, Amit; Kyle, Jennifer E.; Lamichhane, Santosh; Li, Yuan; Nam, Seo Lin; Mandal, Rupasri; de la Mata, A. Paulina; Meehan, Michael J.; Meikopoulos, Thomas; Metz, Thomas O.; Mouskeftara, Thomai; Munoz, Nathalie; Gowda, G. A. Nagana; Oresic, Matej; Panitchpakdi, Morgan; Pierre-Hugues, Stefanuto; Raftery, Daniel; Rushing, Blake; Schock, Tracey; Seifried, Harold; Servetas, Stephanie; Shen, Tong; Sumner, Susan; Carrillo, Kieran S. Tarazona; Thibaut, Dejong; Trejo, Jesse B.; Van Meulebroek, Lieven; Vanhaecke, Lynn; Virgiliou, Christina; Weldon, Kelly C.; Wishart, David S.; Zhang, Lu; Zheng, Jiamin; Da Silva, Sandra 分享 收藏
Targeted sulfur(VI) fluoride exchange-mediated covalent modification of a tyrosine residue in the catalytic pocket of tyrosyl-DNA phosphodiesterase 1 酪氨酰-DNA磷酸二酯酶1催化袋中酪氨酸残基的靶向硫 (VI) 氟交换介导的共价修饰 Zhao, Xue Zhi; Barakat, Idris A.; Lountos, George T.; Wang, Wenjie; Agama, Keli; Al Mahmud, Md Rasel; Suazo, Kiall F.; Andresson, Thorkell; Pommier, Yves; Burke Jr, Terrence R. 分享 收藏
A patient-derived cell model for malignant transformation in IDH-mutant glioma Kim, Olga; Sergi, Zach; Yu, Guangyang; Yamamoto, Kazutoshi; Quezado, Martha; Abdullaev, Zied; Crooks, Danel R.; Kishimoto, Shun; Li, Qi; Lu, Peng; Blackman, Burchelle; Andresson, Thorkell; Wu, Xiaolin; Tran, Bao; Wei, Jun S.; Zhang, Wei; Zhang, Meili; Song, Hua; Khan, Javed; Krishna, Murali C.; Brender, Jeffrey R.; Wu, Jing 分享 收藏
Tyrosine phosphorylation of both STAT5A and STAT5B is necessary for maximal IL-2 signaling and T cell proliferation Lin, Jian-Xin; Ge, Meili; Liu, Cheng-yu; Holewinski, Ronald; Andresson, Thorkell; Yu, Zu-Xi; Gebregiorgis, Tesfay; Spolski, Rosanne; Li, Peng; Leonard, Warren J. 分享 收藏
Genome-scale exon perturbation screens uncover exons critical for cell fitness Xiao, Mei-Sheng; Damodaran, Arun Prasath; Kumari, Bandana; Dickson, Ethan; Xing, Kun; On, Tyler A.; Parab, Nikhil; King, Helen E.; Perez, Alexendar R.; Guiblet, Wilfried M.; Duncan, Gerard; Che, Anney; Chari, Raj; Andresson, Thorkell; Vidigal, Joana A.; Weatheritt, Robert J.; Aregger, Michael; Gonatopoulos-Pournatzis, Thomas 分享 收藏
Sphingolipid biosynthesis is essential for metabolic rewiring during TH17 cell differentiation Abimannan, Thiruvaimozhi; Parthibane, Velayoudame; Le, Si-Hung; Vijaykrishna, Nagampalli; Fox, Stephen D.; Karim, Baktiar; Kunduri, Govind; Blankenberg, Daniel; Andresson, Thorkell; Bamba, Takeshi; Acharya, Usha; Acharya, Jairaj K. 分享 收藏
Discovery of a Tunable Heterocyclic Electrophile 4-Chloro-pyrazolopyridine That Defines a Unique Subset of Ligandable Cysteines Kim, Hong-Rae; Byun, David P.; Thakur, Kalyani; Ritchie, Jennifer; Xie, Yixin; Holewinski, Ronald; Suazo, Kiall F.; Stevens, Mckayla; Liechty, Hope; Tagirasa, Ravichandra; Jing, Yihang; Andresson, Thorkell; Johnson, Steven M.; Yoo, Euna 分享 收藏
Integrated multi-omics revealed the involvement of MYC and mTOR pathways in radiation resistance of adrenocortical cancer Ramamoorthy, Bhavishya; Mishra, Prachi; Boufraqech, Myriem; Michael, Nicholas; Cam, Margaret; Finney, Richard; Meyer, Thomas; Holewinski, Ronald; Andresson, Thorkell; Wong, Madeline; Shema, Steven; Tillo, Desiree; Nilubol, Naris 分享 收藏
A structure-based designed small molecule depletes hRpn13Pru and a select group of KEN box proteins Lu, Xiuxiu; Chandravanshi, Monika; Sabbasani, Venkata R.; Gaikwad, Snehal; Hughitt, V. Keith; Gyabaah-Kessie, Nana; Scroggins, Bradley T.; Das, Sudipto; Myint, Wazo; Clapp, Michelle E.; Schwieters, Charles D.; Dyba, Marzena A.; Bolhuis, Derek L.; Koscielniak, Janusz W.; Andresson, Thorkell; Emanuele, Michael J.; Brown, Nicholas G.; Matsuo, Hiroshi; Chari, Raj; Citrin, Deborah E.; Mock, Beverly A.; Swenson, Rolf E.; Walters, Kylie J. 分享 收藏
Metabolism-focused CRISPR screen unveils mitochondrial pyruvate carrier 1 as a critical driver for PARP inhibitor resistance in lung cancer Furusawa, Takashi; Cavero, Renzo; Liu, Yue; Li, Haojian; Xu, Xia; Andresson, Thorkell; Reinhold, William; White, Olivia; Boufraqech, Myriem; Meyer, Thomas J.; Hartmann, Oliver; Diefenbacher, Markus E.; Pommier, Yves; Weyemi, Urbain 分享 收藏
Rewiring of RNA methylation by the oncometabolite fumarate in renal cell carcinoma Fitzsimmons, Christina M.; Mandler, Mariana D.; Lunger, Judith C.; Chan, Dalen; Maligireddy, Siddhardha S.; Schmiechen, Alexandra C.; Gamage, Supuni Thalalla; Link, Courtney; Jenkins, Lisa M.; Chan, King; Andresson, Thorkell; Crooks, Daniel R.; Meier, Jordan L.; Linehan, W. Marston; Batista, Pedro J. 分享 收藏
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