未登录 SAFETY AND EFFICACY OF BRAF INHIBITOR PLIXORAFENIB (FORE8394; PLX8394) IN CHILDREN AND ADULTS WITH RECURRENT, BRAF-ALTERED PRIMARY CENTRAL NERVOUS SYSTEM TUMORS (PCNST) de la Fuente, Macarena; Butowski, Nicholas A.; Taylor, Jennie; Yaeger, Rona; Tsai, Frank Y-C; Janku, Filip; Allen, Carl E.; Ammakkanavar, Natraj; Michelson, Glenn; Jiang, Ping; Samara, Emil; Paz, Michael; Tussay-Lindenberg, Alexia; Wang, Kongming; Shepherd, Stacie P.; Kline, Irina; Sherman, Eric; Rodon, Jordi 分享 收藏
MRT-6160, A VAV1-DIRECTED MOLECULAR GLUE DEGRADER, REDUCES JOINT INFLAMMATION, CYTOKINE PRODUCTION, AND AUTOANTIBODY LEVELS IN A COLLAGEN-INDUCED ARTHRITIS DISEASE MODEL MRT-6160，一种VAV1定向分子胶降解剂，可降低胶原诱导性关节炎疾病模型中的关节炎症、细胞因子产生和自身抗体水平。 Cartwright, A.; Desai, F.; Vora, S.; Gyger, L.; Roditi, L.; Nguyen, S.; Trouilloud, A.; Lam, D.; Trenh, P.; Lucas, X.; Zlotosch, M.; Liardo, E.; Wible, D.; Oleinikovas, V.; Lamberto, I.; Demarco, B.; King, C.; Bonenfant, D.; Krishnan, E.; De Beukelaer, S.; Townson, S.; Wallace, O.; Janku, F.; Mcallister, L.; Paterson, A.; Peluso, M. 分享 收藏
Liquid Biopsy Response Evaluation Criteria in Solid Tumors (LB-RECIST) 实体瘤的液体活检反应评估标准 (lb-recist) Gouda, M. A.; Janku, F.; Wahida, A.; Buschhorn, L.; Schneeweiss, A.; Karim, N. Abdel; Perez, D. De Miguel; Del Re, M.; Russo, A.; Curigliano, G.; Rolfo, C.; Subbiah, V. 分享 收藏
First-in-human study of naporafenib (LXH254) with or without spartalizumab in adult patients with advanced solid tumors harboring MAPK signaling pathway alterations naporafenib (LXH254) 联合或不联合spartalizumab在患有MAPK信号通路改变的晚期实体瘤成年患者中的首次人体研究 Janku, Filip; Kim, Tae Min; Iyer, Gopakumar; Spreafico, Anna; Elez, Elena; de Jonge, Maja; Yamamoto, Noboru; van der Wekken, Anthonie J.; Ascierto, Paolo Antonio; Maur, Michela; Marme, Frederik; Kiladjian, Jean-Jacques; Basu, Sumit; Baffert, Fabienne; Buigues, Amparo; Chen, Chi; Cook, Vesselina; Giorgetti, Elisa; Kim, Jaeyeon; McCarthy, Fiona; Moschetta, Michele; Dummer, Reinhard 分享 收藏
Concordance between tumor tissue and plasma genotyping in NCI-MATCH Trial (EAY131) Gouda, Mohamed A.; Janku, Filip; Yuan, Ying; Drusbosky, Leylah; Chen, Alice P.; Patel, Keyur; Hamilton, Stanley R.; Routbort, Mark; Williams, P. Mickey; Iafrate, John; Sklar, Jeffrey; Coffey, Brent; Little, Richard F.; Arteaga, Carlos L.; Abrams, Jeffrey S.; O'Dwyer, Peter J.; Flaherty, Keith T.; Harris, Lyndsay N.; Meric-Bernstam, Funda 分享 收藏
分享 收藏
Development of MRT-2359, an orally bioavailable GSPT1 molecular glue degrader, for the treatment of lung cancers with MYC-induced translational addiction Gavory, Gerald; Ghandi, Mahmoud; d'Alessandro, Anne-Cecile; Bonenfant, Debora; Cabanski, Maciej; Cantagallo, Lisa; Chicas, Agustin; Chen, Qian; Diesslin, Anna; King, Christopher; Massafra, Vittoria; Narayan, Rajiv; Osmont, Arnaud; Peck, Dave; Ortiz, Carolina Perdomo; Schillo, Martin; Singh, Ambika; Tiedt, Ralph; Tortoioli, Simone; Buonamici, Silvia; Janku, Filip; Wallace, Owen; Fasching, Bernhard 分享 收藏
A phase 1/2a safety, pharmacokinetics, and efficacy study of the novel nucleoside analog FF-10502-01 for the treatment of advanced solid tumors Janku, Filip; Javle, Milind M.; Sen, Shiraj; Pant, Shubham; Bramwell, Lindsay G.; Subbiah, Vivek; Way, Tracey; Wages, David S.; Wheeler, Catherine A.; Suzuki, Takeaki; Saeki, Kazunori; Subach, Ruth Ann; Madden, Timothy; Maier, Gary; Johansen, Mary J.; Cheung, Kin; Falchook, Gerald S. 分享 收藏
BRAF v600E-mutant cancers treated with vemurafenib alone or in combination with everolimus, sorafenib, or crizotinib or with paclitaxel and carboplatin (VEM-PLUS) study 单独使用维罗非尼或与依维莫司，索拉非尼或克唑替尼或紫杉醇和卡铂联合治疗的BRAF v600E-mutant癌症 (vem-plus) 研究 Nelson, Blessie Elizabeth; Roszik, Jason; Janku, Filip; Hong, David S.; Kato, Shumei; Naing, Aung; Piha-Paul, Sarina; Fu, Siqing; Tsimberidou, Apostolia; Cabanillas, Maria; Busaidy, Naifa Lamki; Javle, Milind; Byers, Lauren Averett; Heymach, John V.; Meric-Bernstam, Funda; Subbiah, Vivek 分享 收藏
Challenges and opportunities associated with the MD Anderson IMPACT2 randomized study in precision oncology 与MD Anderson IMPACT2精准肿瘤学随机研究相关的挑战和机遇 Vo, Henry Hiep; Fu, Siqing; Hong, David S.; Karp, Daniel D.; Piha-Paul, Sarina; Subbiah, Vivek; Janku, Filip; Naing, Aung; Yap, Timothy A.; Rodon, Jordi; Ajani, Jaffer A.; Cartwright, Carrie; Johnson, Amber; Song, I-Wen; Beck, Jennifer; Kahle, Michael; Nogueras-Gonzalez, Graciela M.; Miller, Vincent; Chao, Calvin; Vining, David J.; Berry, Donald A.; Meric-Bernstam, Funda; Tsimberidou, Apostolia-Maria 分享 收藏
Patient-reported symptom burden in patients with rare cancers receiving pembrolizumab in a phase II Clinical Trial 在II期临床试验中接受pembrolizumab治疗的罕见癌症患者的患者报告症状负担 Mendoza, Tito R.; Hong, David S.; Peterson, Christine B.; Stephen, Bettzy; Dumbrava, Ecaterina; Pant, Shubbam; Tsimberidou, Apostolia Maria; Yap, Timothy Anthony; Sheshadri, Ajay; Altan, Mehmet; George, Goldy; Castillo, Lilibeth; Rodriguez, Enedelia; Gong, Jing; Subbiah, Vivek; Janku, Filip; Fu, Siqing; Piha-Paul, Sarina A.; Ahnert, Jordi Rodon; Karp, Daniel D.; Cleeland, Charles; Meric-Bernstam, Funda; Naing, Aung 分享 收藏
Efficacy and safety of ripretinib in patients with KIT-altered metastatic melanoma Janku, F.; Bauer, S.; Shoumariyeh, K.; Jones, R. L.; Spreafico, A.; Jennings, J.; Psoinos, C.; Meade, J.; Ruiz-Soto, R.; Chi, P. 分享 收藏
First-in-human study of IM156, a novel potent biguanide oxidative phosphorylation (OXPHOS) inhibitor, in patients with advanced solid tumors Janku, Filip; Beom, Seung-Hoon; Moon, Yong Wha; Kim, Tae Won; Shin, Young G.; Yim, Dong-Seok; Kim, Gun Min; Kim, Hyo Song; Kim, Sun Young; Cheong, Jae-Ho; Lee, Young Woo; Geiger, Barb; Yoo, Sanghee; Thurston, Archie; Welsch, Dean; Rudoltz, Marc S.; Rha, Sun Young 分享 收藏
Clinical characteristics and outcomes of phase I cancer patients with CCNE1 amplification: MD Anderson experiences Yao, Shuyang; Meric-Bernstam, Funda; Hong, David; Janku, Filip; Naing, Aung; Piha-Paul, Sarina Anne; Tsimberidou, Apostolia Maria; Karp, Daniel; Subbiah, Vivek; Yap, Timothy Anthony; Ahnert, Jordi Rodon; Pant, Shubham; Dumbrava, Ecaterina E. Ileana; Wathoo, Chetna; Campbell, Erick; Yu, Lihou; Yamamura, Yuko; Fu, Siqing 分享 收藏
分享 收藏
Ultrasensitive detection of BRAF mutations in circulating tumor DNA of non-metastatic melanoma 超灵敏检测非转移性黑色素瘤循环肿瘤DNA中BRAF突变 Gouda, M. A.; Polivka, J.; Huang, H. J.; Treskova, I; Pivovarcikova, K.; Fikrle, T.; Woznica, V; Dustin, D. J.; Call, S. G.; Meric-Bernstam, F.; Pesta, M.; Janku, F. 分享 收藏
Selinexor in combination with standard chemotherapy in patients with advanced or metastatic solid tumors Thein, Kyaw Z.; Piha-Paul, Sarina A.; Tsimberidou, Apostolia; Karp, Daniel D.; Janku, Filip; Fu, Siqing; Subbiah, Vivek; Hong, David S.; Yap, Timothy A.; Shah, Jatin; Milton, Denai R.; McQuinn, Lacey; Gong, Jing; Tran, Yanyan; Carter, Brett W.; Colen, Rivka; Meric-Bernstam, Funda; Naing, Aung 分享 收藏
Hormonal modulation of ESR1 mutant metastasis (vol 40, pg 997, 2021) Gu, Guowei; Tian, Lin; Herzog, Sarah K.; Rechoum, Yassine; Gelsomino, Luca; Gao, Meng; Du, Lili; Kim, Jin-Ah; Dustin, Derek; Lo, Hin Ching; Beyer, Amanda R.; Edwards, David G.; Gonzalez, Thomas; Tsimelzon, Anna; Huang, Helen J.; Fernandez, Natalie M.; Grimm, Sandra L.; Hilsenbeck, Susan G.; Liu, Dan; Xu, Jun; Alaniz, Alyssa; Li, Shunqiang; Mills, Gordon B.; Janku, Filip; Kittler, Ralf; Zhang, Xiang H. -F.; Coarfa, Cristian; Foulds, Charles E.; Symmans, W. Fraser; Ando, Sebastiano; Fuqua, Suzanne A. W. 分享 收藏
PRELIMINARY EFFICACY OF THE IL-15 SUPERAGONIST SO-C101 IN COMBINATION WITH PEMBROLIZUMAB IN PATIENTS WITH ADVANCED/METASTATIC SOLID TUMORS Garralda, Elena; Galvao, Vladimir; Champiat, Stephane; LoRusso, Patricia; Grell, Peter; Naing, Aung; Janku, Filip; Sachse, Richard; Bechard, David; Kiemle-Kallee, Joachim; Marabelle, Aurelien; Garralda, Elena 分享 收藏
Selinexor in combination with carboplatin and paclitaxel in patients with advanced solid tumors: results of a single-center, multi-arm phase Ib study (Sep, 10.1007/s10637-021-01188-1, 2021) Thein, Kyaw Z.; Karp, Daniel D.; Tsimberidou, Apostolia; Gong, Jing; Sulovic, Selma; Shah, Jatin; Milton, Denai R.; Hong, David S.; Janku, Filip; McQuinn, Lacey; Stephen, Bettzy A.; Colen, Rivka; Carter, Brett W.; Yap, Timothy A.; Piha-Paul, Sarina A.; Fu, Siqing; Meric-Bernstam, Funda; Naing, Aung 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
