未登录HER2 alterations across solid tumors: implications for comprehensive testingHER2变异在实体瘤中的分布：全面检测的意义
Ismail, Ahmed; Jani, Chimay; Jahan, Nusrat; Midhun, Malla; Basu, Arnab; Gupta, Garima; El-Rayes, Bassel; Bae, Sejong; Mattox, Tyler; Hawkins, Cyntanna; Arend, Rebecca C.; Akce, Mehmet; Boumber, Yanis; Desai, Aakash .png)
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收藏分享 收藏 HER2 expression across solid tumors and real-world implications for use of fam-trastuzumab deruxtecan-nxki (T-Dxd)HER2在实体瘤中的表达及其对fam-trastuzumab deruxtecan-nxki（T-Dxd）临床应用的实际影响Ismail, A.; Modi, M.; Kleckley, A.; Midhun, M.; Basu, A.; Jahan, N.; Gupta, G.; El-Rayes, B.; Mattox, T.; Hawkins, C.; Bae, S.; Akce, M.; Arend, R.; Boumber, Y.; Desai, A. 分享 收藏 Opposing roles of SPOP mutations in human prostate and endometrial cancersCavalcante, Ludimila; Desmukh, Sachin K.; Carneiro, Benedito A.; Angara, Kartik; Mattox, Tyler E.; Wu, Sharon; Xiu, Joanne; Walker, Philip; Oberley, Matthew; Nabhan, Chadi; Antonarakis, Emmanuel S. 分享 收藏 Oncogenic KRAS inhibition with ADT-007 primes T cell responses in pancreatic ductal adenocarcinomaFoote, Jeremy B.; Mattox, Tyler E.; Keeton, Adam B.; Purnachandra, Ganji N.; Maxuitenko, Yulia; Chen, Xi; Valiyaveettil, Jacob; Buchsbaum, Donald J.; Piazza, Gary A.; El-Rayes, Bassel F. 分享 收藏 ADT-007 binds RAS and inhibits RAS signalingKeeton, Adam B.; Chen, Xi; Valiyaveettil, Jacob; Huang, Chung-Hui; Mattox, Tyler E.; Fadlalla, Khalda; Foote, Jeremy B.; Buchsbaum, Donald J.; Berry, Kristy L.; Nurmemmedov, Elmar; Babic, Ivan; Gaponenko, Vadim; Gorman, Gregory; Coward, Lori; Maxuitenko, Yulia Y.; Smith, Forrest T.; Piazza, Gary A. 分享 收藏 A novel PDE10/β-catenin pathway inhibitor, MCI-030, for the treatment of colorectal cancerWard, Antonio B.; Chen, Xi; Valiyaveettil, Jacob; Lee, Kevin; Chang, Wen-Chi L.; Maxuitenko, Yulia; Ramirez-Alcantara, Veronica; Berry, Kristy; da Silva, Luciana Madeira; Zhu, Bing; Mattox, Tyler; Boyd, Michael R.; Keeton, Adam B.; Clapper, Margie L.; Cooper, Harry S.; Piazza, Gary A. 分享 收藏 Targeting RAS and downstream signaling in high-grade serous ovarian carcinoma with novel RAS inhibitorsMattox, Tyler E.; Norton, Tiffany S.; Keeton, Adam B.; Ward, Antonio B.; Maxuitenko, Yulia Y.; Berry, Kristy L.; Zhu, Bing; Musiyenko, Alla; Gavin, Elaine; Ramirez-Alcantara, Veronica; Chen, Xi; Valiyaveettil, Jacob; Scalici, Jennifer; Rocconi, Rodney P.; Piazza, Gary A.; da Silva, Luciana Madeira 分享 收藏 Novel RAS inhibitor, MCI-062, potently and selectively inhibits the growth of KRAS mutant pancreatic tumor cells by blocking GTP loading of RASMattox, Tyler E.; Chen, Xi; Valiyaveettil, Jacob; Maxuitenko, Yulia; Zhu, Bing; Ward, Antonio; Ramirez-Alcantara, Veronica; Berry, Kristy; Boyd, Michael; Keeton, Adam; Piazza, Gary A. 分享 收藏 A novel RAS inhibitor, MCI-062, inhibits colon tumor growth in vivo and activates antitumor immunityKeeton, Adam B.; Ward, Antonio; Chen, Xi; Valiyaveettil, Jacob; Zhu, Bing; Ramirez-Alcantara, Veronica; Maxuitenko, Yulia; Berry, Kristy; Mattox, Tyler E.; Boyd, Michael R.; Piazza, Gary A. 分享 收藏 Inhibition of a novel cancer target, PDE10, suppresses Wnt/β-catenin signaling and colon tumorigenesis: Benefits from combining with ornithine decarboxylase inhibitorsPiazza, Gary A.; Neese, Ashleigh; Lee, Kevin; Keeton, Adam; Maxuitenko, Yulia; Alcantara, Veronica Ramirez; Berry, Kristy; Valiyaveettil, Jacob; Ward, Antonio; da Silva, Luciana Madeira; Scalici, Jennifer; Zhu, Bing; Mattox, Tyler; Chen, Xi; Clapper, Margie; Cooper, Harry; Chang, Wen-Chi 分享 收藏 Novel RAS inhibitors DC070-547 and ADT-006 potently and selectively inhibit the growth of pancreatic tumor cells harboring constitutively activated RAS by blocking RAS-effector binding and signalingMattox, Tyler E.; Lee, Kevin J.; Chen, Xi; Valiyaveettil, Jacob; da Silva, Luciana Madeira; Lindsey, Ashley S.; Keeton, Adam B.; Zhu, Bing; Boyd, Michael; Piazza, Gary A. 分享 收藏 Sensitivity of melanoma cells to a novel class of Ras inhibitorsSaville, Kate M.; Lee, Kevin; Mattox, Tyler E.; Chen, Xi; Valiyaveettil, Jacob; Berry, Kristy; Ramirez-Alcantara, Veronica; Zhu, Bing; Keeton, Adam; Boyd, Michael; Piazza, Gary; Lindsey, Ashley S. 分享 收藏 Characterization of a novel class of RAS inhibitory compounds with potent anti-tumor activityWard, Antonio; Chen, Xi; Valiyaveettil, Jacob; Zhu, Bing; Ramirez-Alcantara, Veronica; Lee, Kevin J.; Lindsey, Ashley; Berry, Kristy; Mattox, Tyler E.; McConnell, Kate; Boyd, Michael R.; Piazza, Gary A.; Keeton, Adam B. 分享 收藏 Discovery and in vitro and in vivo characterization of a novel, small-molecule Ras inhibitor classKeeton, Adam B.; Zhu, Bing; Lee, Kevin J.; Canzoneri, Joshua C.; Sigler, Sara C.; Lindsey, Ashley S.; Ramirez-Alcantara, Veronica; Barnes, Luciana; Mattox, Tyler E.; McConnell, Kate; Berry, Kristy L.; Valiyaveettil, Jacob; Chen, Xi; Boyd, Michael R.; Piazza, Gary A. 分享 收藏 
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