未登录 Circulating T cell receptor repertoire analysis improves cancer early detection Li, Yilong; Nahas, Michelle; Stephens, Dennis; Froburg, Kate; Hintz, Emma; Champagne, Devin; Lochab, Amaneet; Brown, Markus; Abhyankar, Jesse; Braun, Jasper; Dinh, Michelle; Fortuno, Maria Antonia; Ocon, Maria-del-Mar; Pasquier, Andrea; Luque, Ines Maria; Seder, Christopher W.; Borgia, Jeffrey A.; Seijo, Luis Miguel; Montuenga, Luis M.; Yelensky, Roman 分享 收藏
Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim results 个体化异源黑猩猩腺病毒和自我扩增mRNA新抗原疫苗治疗晚期转移性实体瘤: 1期试验中期结果 Palmer, Christine D.; Rappaport, Amy R.; Davis, Matthew J.; Hart, Meghan G.; Scallan, Ciaran D.; Hong, Sue-Jean; Gitlin, Leonid; Kraemer, Lauren D.; Kounlavouth, Sonia; Yang, Aaron; Smith, Lindsey; Schenk, Desiree; Skoberne, Mojca; Taquechel, Kiara; Marrali, Martina; Jaroslavsky, Jason R.; Nganje, Charmaine N.; Maloney, Elizabeth; Zhou, Rita; Navarro-Gomez, Daniel; Greene, Adrienne C.; Grotenbreg, Gijsbert; Greer, Renee; Blair, Wade; Cao, Minh Duc; Chan, Shawn; Bae, Kyounghwa; Spira, Alexander I.; Roychowdhury, Sameek; Carbone, David P.; Henick, Brian S.; Drake, Charles G.; Solomon, Benjamin J.; Ahn, Daniel H.; Mahipal, Amit; Maron, Steve B.; Johnson, Benny; Rousseau, Raphael; Yelensky, Roman; Liao, Chih-Yi; Catenacci, Daniel V. T.; Allen, Andrew; Ferguson, Andrew R.; Jooss, Karin 分享 收藏
Identification of pre-existing neoantigen-specific T cells in patients receiving checkpoint inhibitor therapy using a deep learning antigen prediction model Palmer, Christine D.; Bulik, Brendan; Yang, Aaron; Hart, Meghan; Davis, Matthew; Francis, Joshua; Duke, Fujiko; Zhou, Rita; Busby, Jennifer; Murphy, Tyler; Clark, Andrew; Young, Lauren; Zhong, Mike; Caldwell, Kamilah; Abhyankar, Jesse; Cook, Alison; Boucher, Tommy; Rousseau, Raphael; Voong, Cynthia; Rizvi, Naiyer; Frattini, Mark; Yelensky, Roman; Jooss, Karin; Skoberne, Mojca 分享 收藏
MHC class II antigen identification for cancer immunotherapy by deep learning on tumor HLA peptides Boucher, Tommy; Davis, Matthew; Palmer, Christine; Murphy, Tyler; Clark, Andrew; Duke, Fujiko; Yang, Aaron; Young, Lauren; Jooss, Karin; Skoberne, Mojca; Francis, Josh; Yelensky, Roman; Sun, James; Busby, Jennifer 分享 收藏
Deep learning using tumor HLA peptide mass spectrometry datasets improves neoantigen identification Bulik-Sullivan, Brendan; Busby, Jennifer; Palmer, Christine D.; Davis, Matthew J.; Murphy, Tyler; Clark, Andrew; Busby, Michele; Duke, Fujiko; Yang, Aaron; Young, Lauren; Ojo, Noelle C.; Caldwell, Kamilah; Abhyankar, Jesse; Boucher, Thomas; Hart, Meghan G.; Makarov, Vladimir; De Montpreville, Vincent Thomas; Mercier, Olaf; Chan, Timothy A.; Scagliotti, Giorgio; Bironzo, Paolo; Novello, Silvia; Karachaliou, Niki; Rosell, Rafael; Anderson, Ian; Gabrail, Nashat; Hrom, John; Limvarapuss, Chainarong; Choquette, Karin; Spira, Alexander; Rousseau, Raphael; Voong, Cynthia; Rizvi, Naiyer A.; Fadel, Elie; Frattini, Mark; Jooss, Karin; Skoberne, Mojca; Francis, Joshua; Yelensky, Roman 分享 收藏
Antigen identification for cancer immunotherapy by deep learning on tumor HLA peptides Bulik-Sullivan, Brendan; Busby, Jennifer; Davis, Matthew; Young, Lauren; Murphy, Tyler; Clark, Andrew; Duke, Fujiko; Busby, Michele; Derti, Adnan; Skoberne, Mojca; Jooss, Karin; Gustafson, Corinne E.; De Rienzo, Assunta; Richards, William G.; Dao, Nhien T.; Kim, Hyeong R.; Anderson, Jamie E.; Choi, Chang-Min; De Montpreville, Vincent; Jang, Se Jin; Mercier, Olaf; Bueno, Raphael; Fadel, Elie; Francis, Joshua; Yelensky, Roman 分享 收藏
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A computational approach to distinguish somatic vs. germline origin of genomic alterations from deep sequencing of cancer specimens without a matched normal Sun, James X.; He, Yuting; Sanford, Eric; Montesion, Meagan; Frampton, Garrett M.; Vignot, Phane; Soria, Jean-Charles; Ross, Jeffrey S.; Miller, Vincent A.; Stephens, Phil J.; Lipson, Doron; Yelensky, Roman 分享 收藏
Genomic profiling of ER+ breast cancers after short-term estrogen suppression reveals alterations associated with endocrine resistance Giltnane, Jennifer M.; Hutchinson, Katherine E.; Stricker, Thomas P.; Formisano, Luigi; Young, Christian D.; Estrada, Monica V.; Nixon, Mellissa J.; Du, Liping; Sanchez, Violeta; Ericsson, Paula Gonzalez; Kuba, Maria G.; Sanders, Melinda E.; Mu, Xinmeng J.; Van Allen, Eliezer M.; Wagle, Nikhil; Mayer, Ingrid A.; Abramson, Vandana; Gomez, Henry; Rizzo, Monica; Toy, Weiyi; Chandarlapaty, Sarat; Mayer, Erica L.; Christiansen, Jason; Murphy, Danielle; Fitzgerald, Kerry; Wang, Kai; Ross, Jeffrey S.; Miller, Vincent A.; Stephens, Phillip J.; Yelensky, Roman; Garraway, Levi; Shyr, Yu; Meszoely, Ingrid; Balko, Justin M.; Arteaga, Carlos L. 分享 收藏
An integrated genomic and proteomic analysis of human tumors reveals key factors in neoantigen identification and enables epitope prediction for cancer immunotherapy Bulik-Sullivan, Brendan; Busby, Jennifer; Davis, Matthew; Clark, Andrew; Murphy, Tyler; Busby, Michele; Duke, Fujiko; Smith, Jessica; Hudak, Jason; Derti, Adnan; Francis, Josh; Yelensky, Roman 分享 收藏
TP53 Alterations Correlate with Response to VEGF/VEGFR Inhibitors: Implications for Targeted Therapeutics Wheler, Jennifer J.; Janku, Filip; Naing, Aung; Li, Yali; Stephen, Bettzy; Zinner, Ralph; Subbiah, Vivek; Fu, Siqing; Karp, Daniel; Falchook, Gerald S.; Tsimberidou, Apostolia M.; Piha-Paul, Sarina; Anderson, Roosevelt; Ke, Danxia; Miller, Vincent; Yelensky, Roman; Lee, J. Jack; Hong, David; Kurzrock, Razelle 分享 收藏
Characterization of Clinical Cases of Collecting Duct Carcinoma of the Kidney Assessed by Comprehensive Genomic Profiling Pal, Sumanta K.; Choueiri, Toni K.; Wang, Kai; Khaira, Depinder; Karam, Jose A.; Van Allen, Eliezer; Palma, Norma A.; Stein, Mark N.; Johnson, Adrienne; Squillace, Rachel; Elvin, Julia A.; Chmielecki, Juliann; Yelensky, Roman; Yakirevich, Evgeny; Lipson, Doron; Lin, Douglas I.; Miller, Vincent A.; Stephens, Philip J.; Ali, Siraj M.; Ross, Jeffrey S. 分享 收藏
Broad analysis of recurrent somatic mutations in cancer reveals a common novel non-coding mutation in the promoter of PMS2 associated with greatly increased tumor mutation load Chalmers, Zachary R.; Huang, Franklin W.; Gay, Laurie M.; Ali, Siraj M.; Yelensky, Roman; Chmielecki, Juliann; Ross, Jeffery S.; Miller, Vincent A.; Stephens, Philip J.; Garraway, Levi A.; Frampton, Garrett M. 分享 收藏
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Comprehensive genomic profiling of anal squamous cell carcinoma reveals distinct genomically defined classes Chung, J. H.; Sanford, E.; Johnson, A.; Klempner, S. J.; Schrock, A. B.; Palma, N. A.; Erlich, R. L.; Frampton, G. M.; Chalmers, Z. R.; Vergilio, J.; Rubinson, D. A.; Sun, J. X.; Chmielecki, J.; Yelensky, R.; Suh, J. H.; Lipson, D.; George, T. J., Jr.; Elvin, J. A.; Stephens, P. J.; Miller, V. A.; Ross, J. S.; Ali, S. M. 分享 收藏
Cancer Therapy Directed by Comprehensive Genomic Profiling: A Single Center Study Wheler, Jennifer J.; Janku, Filip; Naing, Aung; Li, Yali; Stephen, Bettzy; Zinner, Ralph; Subbiah, Vivek; Fu, Siqing; Karp, Daniel; Falchook, Gerald S.; Tsimberidou, Apostolia M.; Piha-Paul, Sarina; Anderson, Roosevelt; Ke, Danxia; Miller, Vincent; Yelensky, Roman; Lee, J. Jack; Hong, David S.; Kurzrock, Razelle 分享 收藏
Patient-derived xenotransplants can recapitulate the genetic driver landscape of acute leukemias Wang, K.; Sanchez-Martin, M.; Wang, X.; Knapp, K. M.; Koche, R.; Vu, L.; Nahas, M. K.; He, J.; Hadler, M.; Stein, E. M.; Tallman, M. S.; Donahue, A. L.; Frampton, G. M.; Lipson, D.; Roels, S.; Stephens, P. J.; Sanford, E. M.; Brennan, T.; Otto, G. A.; Yelensky, R.; Miller, V. A.; Kharas, M. G.; Levine, R. L.; Ferrando, A.; Armstrong, S. A.; Krivtsov, A. V. 分享 收藏
Nonamplification ERBB2 genomic alterations in 5605 cases of recurrent and metastatic breast cancer: An emerging opportunity for anti-HER2 targeted therapies Ross, Jeffrey S.; Gay, Laurie M.; Wang, Kai; Ali, Siraj M.; Chumsri, Saranya; Elvin, Julia A.; Bose, Ron; Vergilio, Jo-Anne; Suh, James; Yelensky, Roman; Lipson, Doron; Chmielecki, Juliann; Waintraub, Stanley; Leyland-Jones, Brian; Miller, Vincent A.; Stephens, Philip J. 分享 收藏
Triple-negative breast cancers with amplification of JAK2 at the 9p24 locus demonstrate JAK2-specific dependence Balko, Justin M.; Schwarz, Luis J.; Luo, Na; Estrada, Monica V.; Giltnane, Jennifer M.; Davila-Gonzalez, Daniel; Wang, Kai; Sanchez, Violeta; Dean, Phillip T.; Combs, Susan E.; Hicks, Donna; Pinto, Joseph A.; Landis, Melissa D.; Doimi, Franco D.; Yelensky, Roman; Miller, Vincent A.; Stephens, Phillip J.; Rimm, David L.; Gomez, Henry; Chang, Jenny C.; Sanders, Melinda E.; Cook, Rebecca S.; Arteaga, Carlos L. 分享 收藏
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