Takamitsu Sasaki - Publications, H-index & Citations

Takamitsu Sasaki

department of mechanical engineering and science

46H指数

426论文数

8.6K被引数

收录论文 85

发表时间

Multi-material level set-based topology optimization of compliant mechanisms using moving wide spline curves with constrained ends

Structural and Multidisciplinary Optimization

IF4

2026-07-30

OAAI

Kozo Furuta; Hayate Nakayama; Takamitsu Sasaki; Sei Mineno; Rixin Wang; Benliang Zhu; Kazuhiro Izui; Shinji Nishiwaki

Creatine Kinase Blockade Disrupts Energy Metabolism and Redox Homeostasis to Suppress Osteosarcoma Progression 肌酸激酶阻断破坏能量代谢和氧化还原稳态以抑制骨肉瘤进展

International Journal of Molecular Sciences 2025, Vol. 26, Page 11555

IF4.9

2025-11-28

OAAI

Shingo Kishi; Rika Sasaki; Rina Fujiwara-Tani; Hitoshi Ohmori; Yi Luo; Kiyomu Fujii; Takamitsu Sasaki; Kei Goto; Yoshihiro Miyagawa; Isao Kawahara; Ryoichi Nishida; Shota Nukaga; Yukiko Nishiguchi; Ruiko Ogata; Kanya Honoki; Hiroki Kuniyasu

Data-driven topology optimization of all-solid-state batteries considering conductive additive material informed by microstructure analysis 基于微观结构分析的数据驱动全固态电池拓扑优化，考虑导电添加剂材料

Structural and Multidisciplinary Optimization

IF4

2025-08-25

OAAI

Naoyuki Ishida; Kozo Furuta; Masashi Kishimoto; Takamitsu Sasaki; Hiroshi Iwai; Kazuhiro Izui; Shinji Nishiwaki

Association between drug-induced heart failure and CYP1A1, CYP1B1, and CYP3A4 inhibition: Utility of cytochrome P450 inhibition assay for evaluating cardiotoxicity of drug candidates 药物诱导性心力衰竭与CYP1A1、CYP1B1和CYP3A4抑制之间的关联：细胞色素P450抑制测定法在评估药物候选物心脏毒性中的效用

Toxicology in Vitro

IF2.7

2025-05-30

PREAI

Shunnosuke Kaito; Kiyomi Sato; Takamitsu Sasaki; Takuomi Hosaka; Ryota Shizu; Jun-ichi Takeshita; Kouichi Yoshinari

Caprylic Acid Restores Branched-Chain Amino Acid Metabolism in a Mouse Cachexia Model 辛酸恢复小鼠恶病质模型中的支链氨基酸代谢

CURRENT ISSUES IN MOLECULAR BIOLOGY

IF3

2025-05-01

OAAI

Kawahara, Isao; Fujiwara-Tani, Rina; Mori, Takuya; Nukaga, Shota; Nishida, Ryoichi; Miyagawa, Yoshihiro; Goto, Kei; Ohmori, Hitoshi; Fujii, Kiyomu; Luo, Yi; Sasaki, Takamitsu; Nakashima, Chie; Ogata, Ruiko; Kuniyasu, Hiroki

Anti-Cancer and Pro-Immune Effects of Lauric Acid on Colorectal Cancer Cells 月桂酸对结直肠癌细胞抗癌和促免疫效应

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2025-02-24

OAAI

Mori, Shiori; Fujiwara-Tani, Rina; Ogata, Ruiko; Ohmori, Hitoshi; Fujii, Kiyomu; Luo, Yi; Sasaki, Takamitsu; Nishiguchi, Yukiko; Bhawal, Ujjal Kumar; Kishi, Shingo; Kuniyasu, Hiroki

Oxidative High Mobility Group Box-1 Accelerates Mitochondrial Transfer from Mesenchymal Stem Cells to Colorectal Cancer Cells Providing Cancer Cell Stemness 氧化性高迁移率族蛋白1加速间充质干细胞向结直肠癌细胞转移线粒体，赋予癌细胞干性

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2025-01-30

OAAI

Sasaki, Rika; Luo, Yi; Kishi, Shingo; Ogata, Ruiko; Nishiguchi, Yukiko; Sasaki, Takamitsu; Ohmori, Hitoshi; Fujiwara-Tani, Rina; Kuniyasu, Hiroki

Significance of Malic Enzyme 1 in Cancer: A Review 苹果酸酶1在癌症中的意义：综述

CURRENT ISSUES IN MOLECULAR BIOLOGY

IF3

2025-01-29

OAAI

Fujiwara-Tani, Rina; Nakashima, Chie; Ohmori, Hitoshi; Fujii, Kiyomu; Luo, Yi; Sasaki, Takamitsu; Ogata, Ruiko; Kuniyasu, Hiroki

Energy Metabolism and Stemness and the Role of Lauric Acid in Reversing 5-Fluorouracil Resistance in Colorectal Cancer Cells 能量代谢与干细胞特性及月桂酸在逆转结直肠癌细胞5-氟尿嘧啶耐药性中的作用

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

IF4.9

2025-01-14

OAAI

Fujiwara-Tani, Rina; Luo, Yi; Ogata, Ruiko; Fujii, Kiyomu; Sasaki, Takamitsu; Sasaki, Rika; Nishiguchi, Yukiko; Mori, Shiori; Ohmori, Hitoshi

Topology optimization for 3D fluid diode design considering wall-connected structures 考虑壁连接结构的3D流体二极管设计的拓扑优化

STRUCTURAL AND MULTIDISCIPLINARY OPTIMIZATION

IF4

2024-12-09

OAAI

Sasaki, Takamitsu; Furuta, Kozo; Ishida, Naoyuki; Li, Hao; Kondoh, Tsuguo; Izui, Kazuhiro; Nishiwaki, Shinji

Comprehensive analysis of the toxicity-related findings from repeated-dose subacute toxicity studies of industrial chemicals in male rats

CRITICAL REVIEWS IN TOXICOLOGY

IF4.1

2024-12-05

OAAI

Takeshita, Jun-ichi; Goto, Yoshitaka; Yamamoto, Shinji; Sasaki, Takamitsu; Yoshinari, Kouichi

Machine Learning-Based In Silico Prediction of the Inhibitory Activity of Chemical Substances Against Rat and Human Cytochrome P450s

CHEMICAL RESEARCH IN TOXICOLOGY

IF3.8

2024-10-20

OAAI

Ambe, Kaori; Nakamori, Mizuki; Tohno, Riku; Suzuki, Kotaro; Sasaki, Takamitsu; Tohkin, Masahiro; Yoshinari, Kouichi

Differential Effects of Three Medium-Chain Fatty Acids on Mitochondrial Quality Control and Skeletal Muscle Maturation

ANTIOXIDANTS

IF6.6

2024-07-09

OAAI

Nishida, Ryoichi; Nukaga, Shota; Kawahara, Isao; Miyagawa, Yoshihiro; Goto, Kei; Nakashima, Chie; Luo, Yi; Sasaki, Takamitsu; Fujii, Kiyomu; Ohmori, Hitoshi; Ogata, Ruiko; Mori, Shiori; Fujiwara-Tani, Rina; Kuniyasu, Hiroki

Interaction with YAP underlies the species differences between humans and rodents in CAR-dependent hepatocyte proliferation

TOXICOLOGICAL SCIENCES

IF4.1

2023-12-21

PREAI

Shizu, Ryota; Makida, Natsuki; Sobe, Keiichiro; Ishimura, Mai; Takeshita, Aki; Hosaka, Takuomi; Kanno, Yuichiro; Sasaki, Takamitsu; Yoshinari, Kouichi

Multiscale topological design of coated structures with layer-wise bi-material lattice infill for minimum dynamic compliance

COMPOSITE STRUCTURES

IF7.1

2023-11-01

PREAI

Hu, Tiannan; Wang, Yaguang; Zhang, Heng; Li, Hao; Ishida, Naoyuki; Sasaki, Takamitsu; Furuta, Kozo; Izui, Kazuhiro; Nishiwaki, Shinji

Development of a strategy to identify and evaluate direct and indirect activators of constitutive androstane receptor in rats

FOOD AND CHEMICAL TOXICOLOGY

IF3.5

2022-12-01

PREAI

Sato, Takumi; Shizu, Ryota; Miura, Yoshie; Hosaka, Takuomi; Kanno, Yuichiro; Sasaki, Takamitsu; Yoshinari, Kouichi

PXR Suppresses PPARα-Dependent HMGCS2 Gene Transcription by Inhibiting the Interaction between PPARα and PGC1α

CELLS

IF5.2

2021-12-16

OAAI

Shizu, Ryota; Ezaki, Kanako; Sato, Takumi; Sugawara, Ayaka; Hosaka, Takuomi; Sasaki, Takamitsu; Yoshinari, Kouichi

Helix 12 stabilization contributes to basal transcriptional activity of PXR

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2021-09-01

OAAI

Shizu, Ryota; Nishiguchi, Hikaru; Tashiro, Sarii; Sato, Takumi; Sugawara, Ayaka; Kanno, Yuichiro; Hosaka, Takuomi; Sasaki, Takamitsu; Yoshinari, Kouichi

HGCSG1901: A retrospective cohort study evaluating the safety and efficacy of S-1 and irinotecan plus bevacizumab in patients with metastatic colorectal cancer: Analysis of first-line treatment

ANNALS OF ONCOLOGY

IF65.4

2021-07-01

OAAI

Ito, K.; Yuki, S.; Nakano, S.; Yagisawa, M.; Sawada, K.; Ishiguro, A.; Muto, O.; Hatanaka, K.; Okuda, H.; Sato, A.; Sasaki, Y.; Nakamura, M.; Sasaki, T.; Kobayashi, T.; Dazai, M.; Nakatsumi, H.; Ueda, A.; Tateyama, M.; Sogabe, S.; Matsumoto, R.; Sakata, Y.; Komatsu, Y.

HGCSG1901: A retrospective cohort study evaluating the safety and efficacy of S-1 and irinotecan plus bevacizumab in patients with metastatic colorectal cancer: Analysis of second-line treatment after anti-EGFR antibody

ANNALS OF ONCOLOGY

IF65.4

2021-07-01

PREAI

Yoshikawa, A.; Ito, K.; Yuki, S.; Kawamoto, Y.; Saito, R.; Yamamura, T.; Yagisawa, M.; Ishiguro, A.; Muto, O.; Hatanaka, K.; Okuda, H.; Sato, A.; Sasaki, Y.; Nakamura, M.; Sasaki, T.; Kobayashi, T.; Dazai, M.; Nakatsumi, H.; Ueda, A.; Sakata, Y.; Komatsu, Y.

研究方向