未登录 Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration (Vol 14, 2153, 2024) Ramaswami, Gokul; Yuva-Aydemir, Yeliz; Akerberg, Brynn; Matthews, Bryan; Williams, Jenna; Golczer, Gabriel; Huang, Jiaqi; Al Abdullatif, Ali; Huh, Dann; Burkly, Linda C.; Engle, Sandra J.; Grossman, Iris; Sehgal, Alfica; Sigova, Alla A.; Fremeau, Robert T., Jr.; Liu, Yuting; Bumcrot, David 分享 收藏
The Discovery of 7-Isopropoxy-2-(1-methyl-2-oxabicyclo[2.1.1]hexan-4-yl)-N-(6-methylpyrazolo[1,5-a]pyrimidin-3-yl)imidazo[1,2-a]pyrimidine-6-carboxamide (BIO-7488), a Potent, Selective, and CNS-Penetrant IRAK4 Inhibitor for the Treatment of Ischemic Stroke Evans, Ryan; Bolduc, Philippe N.; Pfaffenbach, Magnus; Gao, Fang; May-Dracka, Tricia; Fang, Terry; Hopkins, Brian T.; Chodaparambil, Jayanth, V; Henry, Kate L.; Li, Pei; Metrick, Claire; Nelson, Ashley; Trapa, Patrick; Thomas, Ankur; Burkly, Linda; Peterson, Emily A. 分享 收藏
Transcriptional characterization of iPSC-derived microglia as a model for therapeutic development in neurodegeneration Ramaswami, Gokul; Yuva-Aydemir, Yeliz; Akerberg, Brynn; Matthews, Bryan; Williams, Jenna; Golczer, Gabriel; Huang, Jiaqi; Al Abdullatif, Ali; Huh, Dann; Burkly, Linda C.; Engle, Sandra J.; Sehgal, Alfica; Sigova, Alla A.; Fremeau Jr, Robert T.; Liu, Yuting; Bumcrot, David 分享 收藏
分享 收藏
Multi-ancestry GWAS reveals excitotoxicity associated with outcome after ischaemic stroke Ibanez, Laura; Heitsch, Laura; Carrera, Caty; Farias, Fabiana H. G.; Del Aguila, Jorge L.; Dhar, Rajat; Budde, John; Bergmann, Kristy; Bradley, Joseph; Harari, Oscar; Phuah, Chia Ling; Lemmens, Robin; Viana Oliveira Souza, Alessandro A.; Moniche, Francisco; Cabezas-Juan, Antonio; Arenillas, Juan Francisco; Krupinksi, Jerzy; Cullell, Natalia; Torres-Aguila, Nuria; Muino, Elena; Carcel-Marquez, Jara; Marti-Fabregas, Joan; Delgado-Mederos, Raquel; Marin-Bueno, Rebeca; Hornick, Alejandro; Vives-Bauza, Cristofol; Navarro, Rosa Diaz; Tur, Silvia; Jimenez, Carmen; Obach, Victor; Segura, Tomas; Serrano-Heras, Gemma; Chung, Jong Won; Roquer, Jaume; Soriano-Tarraga, Carol; Giralt-Steinhauer, Eva; Mola-Caminal, Marina; Pera, Joanna; Lapicka-Bodzioch, Katarzyna; Derbisz, Justyna; Davalos, Antoni; Lopez-Cancio, Elena; Munoz, Lucia; Tatlisumak, Turgut; Molina, Carlos; Ribo, Marc; Bustamante, Alejandro; Sobrino, Tomas; Castillo-Sanchez, Jose; Campos, Francisco; Rodriguez-Castro, Emilio; Arias-Rivas, Susana; Rodriguez-Yanez, Manuel; Herbosa, Christina; Ford, Andria L.; Gutierrez-Romero, Alonso; Uribe-Pacheco, Rodrigo; Arauz, Antonio; Lopes-Cendes, Iscia; Lowenkopf, Theodore; Barboza, Miguel A.; Amini, Hajar; Stamova, Boryana; Ander, Bradley P.; Sharp, Frank R.; Kim, Gyeong Moon; Bang, Oh Young; Jimenez-Conde, Jordi; Slowik, Agnieszka; Stribian, Daniel; Tsai, Ellen A.; Burkly, Linda C.; Montaner, Joan; Fernandez-Cadenas, Israel; Lee, Jin Moo; Cruchaga, Carlos 分享 收藏
分享 收藏
Proteomic Characterization of the Dynamics of Ischemic Stroke in Mice Gu, Rong-Fang; Fang, Terry; Nelson, Ashley; Gyoneva, Stefka; Gao, Benbo; Hedde, Joe; Henry, Kate; Peterson, Emily; Burkly, Linda C.; Wei, Ru 分享 收藏
Developmental synaptic regulator, TWEAK/Fn14 signaling, is a determinant of synaptic function in models of stroke and neurodegeneration 发育突触调节因子TWEAK/Fn14信号是中风和神经变性模型中突触功能的决定因素 Nagy, David; Ennis, Katelin A.; Wei, Ru; Su, Susan C.; Hinckley, Christopher A.; Gu, Rong-Fang; Gao, Benbo; Massol, Ramiro H.; Ehrenfels, Chris; Jandreski, Luke; Thomas, Ankur M.; Nelson, Ashley; Gyoneva, Stefka; Hajos, Mihaly; Burkly, Linda C. 分享 收藏
分享 收藏
Cx3cr1-deficient microglia exhibit a premature aging transcriptome Cx3cr1-deficient小胶质细胞表现出过早衰老的转录组 Gyoneva, Stefka; Hosur, Raghavendra; Gosselin, David; Zhang, Baohong; Ouyang, Zhengyu; Cotleur, Anne C.; Peterson, Michael; Allaire, Norm; Challa, Ravi; Cullen, Patrick; Roberts, Chris; Miao, Kelly; Reynolds, Taylor L.; Glass, Christopher K.; Burkly, Linda; Ransohoff, Richard M. 分享 收藏
分享 收藏
Visual Experience-Dependent Expression of Fn14 Is Required for Retinogeniculate Refinement Cheadle, Lucas; Tzeng, Christopher P.; Kalish, Brian T.; Harmin, David A.; Rivera, Samuel; Ling, Emi; Nagy, M. Aurel; Hrvatin, Sinisa; Hu, Linda; Stroud, Hume; Burkly, Linda C.; Chen, Chinfei; Greenberg, Michael E. 分享 收藏
分享 收藏
Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing Vollmann, Elisabeth H.; Cao, Lizhi; Amatucci, Aldo; Reynolds, Taylor; Hamann, Stefan; Dalkilic-Liddle, Isin; Cameron, Thomas O.; Hossbach, Markus; Kauffman, Kevin J.; Mir, Faryal F.; Anderson, Daniel G.; Novobrantseva, Tatiana; Koteliansky, Victor; Kisseleva, Tatiana; Brenner, David; Duffield, Jeremy; Burkly, Linda C. 分享 收藏
分享 收藏
Disruption of the TWEAK/Fn14 pathway prevents 5-fluorouracil-induced diarrhea in mice Sezaki, Takuhito; Hirata, Yuki; Hagiwara, Teruki; Kawamura, Yuki I.; Okamura, Tadashi; Takanashi, Rieko; Nakano, Kenta; Tamura-Nakano, Miwa; Burkly, Linda C.; Dohi, Taeko 分享 收藏
分享 收藏
Interaction of TWEAK with Fn14 leads to the progression of fibrotic liver disease by directly modulating hepatic stellate cell proliferation Wilhelm, Annika; Shepherd, Emma L.; Amatucci, Aldo; Munir, Mamoona; Reynolds, Gary; Humphreys, Elizabeth; Resheq, Yazid; Adams, David H.; Huebscher, Stefan; Burkly, Linda C.; Weston, Christopher J.; Afford, Simon C. 分享 收藏
TWEAK/Fn14 Signaling Involvement in the Pathogenesis of Cutaneous Disease in the MRL/lpr Model of Spontaneous Lupus Doerner, Jessica L.; Wen, Jing; Xia, Yumin; Paz, Karin Blecher; Schairer, David; Wu, Lan; Chalmers, Samantha A.; Izmirly, Peter; Michaelson, Jennifer S.; Burkly, Linda C.; Friedman, Adam J.; Putterman, Chaim 分享 收藏
TNF-like weak inducer of apoptosis promotes blood brain barrier disruption and increases neuronal cell death in MRL/lpr mice Wen, Jing; Doerner, Jessica; Weidenheim, Karen; Xia, Yumin; Stock, Ariel; Michaelson, Jennifer S.; Baruch, Kuti; Deczkowska, Aleksandra; Gulinello, Maria; Schwartz, Michal; Burkly, Linda C.; Putterman, Chaim 分享 收藏
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
