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T

Timothy A. Springer

Harvard University
H指数:165
被引数:11.0万

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A single-chain derivative of an integrin-activating antibody potentiates organoid growth in Matrigel and collagen hydrogels

一种整合素激活抗体的单链衍生物能够增强基质胶和胶原蛋白水凝胶中类器官的生长

Nature Biotechnology
IF41.7
2025-10-280
OAAI
Wim B. M. de Lau; Joost J. A. P. M. Wijnakker; Gijs J. F. van Son; Daniel Krueger; Daisong Wang; Matthijs S. Abendroth; Robin Schreurs; Claudia Y. Janda; Fenna L. H. van Rijt; Benjamin J. P. Chalopin; Emma Bokobza; Johan H. van Es; Timothy A. Springer; Arnoud Sonnenberg; Hans Clevers
De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties

从零设计调控整合素α5β1的蛋白质以增强生物材料性能

Advanced Materials
IF26.8
2025-06-090
OAAI
Xinru Wang; Jordi Guillem-Marti; Saurav Kumar; David S. Lee; Daniel Cabrerizo-Aguado; Rachel Werther; Kevin Alexander Estrada Alamo; Yan Ting Zhao; Adam Nguyen; Irina Kopyeva; Buwei Huang; Jing Li; Yuxin Hao; Xinting Li; Aritza Brizuela-Velasco; Analisa Murray; Stacey Gerben; Anindya Roy; Cole A. DeForest; Timothy Springer; Hannele Ruohola-Baker; Jonathan A. Cooper; Melody G. Campbell; Jose Maria Manero; Maria-Pau Ginebra; David Baker
De novo design of highly selective miniprotein inhibitors of integrins αvβ6 and αvβ8
NATURE COMMUNICATIONS
IF15.7
2023-09-137
OAAI
Roy, Anindya; Shi, Lei; Chang, Ashley; Dong, Xianchi; Fernandez, Andres; Kraft, John C.; Li, Jing; Le, Viet Q.; Winegar, Rebecca Viazzo; Cherf, Gerald Maxwell; Slocum, Dean; Poulson, P. Daniel; Casper, Garrett E.; Vallecillo-Zuniga, Mary L.; Valdoz, Jonard Corpuz; Miranda, Marcos C.; Bai, Hua; Kipnis, Yakov; Olshefsky, Audrey; Priya, Tanu; Carter, Lauren; Ravichandran, Rashmi; Chow, Cameron M.; Johnson, Max R.; Cheng, Suna; Smith, McKaela; Overed-Sayer, Catherine; Finch, Donna K.; Lowe, David; Bera, Asim K.; Matute-Bello, Gustavo; Birkland, Timothy P.; DiMaio, Frank; Raghu, Ganesh; Cochran, Jennifer R.; Stewart, Lance J.; Campbell, Melody G.; Van Ry, Pam M.; Springer, Timothy; Baker, David
Congenital X-linked neutropenia with myelodysplasia and somatic tetraploidy due to a germline mutation in SEPT6
AMERICAN JOURNAL OF HEMATOLOGY
IF9.9
2021-11-032
OA
Renella, Raffaele; Gagne, Katelyn; Beauchamp, Ellen; Fogel, Jonathan; Perlov, Aleksej; Sola, Mireia; Schlaeger, Thorsten; Hofmann, Inga; Shimamura, Akiko; Ebert, Benjamin L.; Schmitz-Abe, Klaus; Markianos, Kyriacos; Murphy, Kristi; Sun, Liang; Rockowitz, Shira; Sliz, Piotr; Campagna, Dean R.; Springer, Timothy A.; Bahl, Christopher; Agarwal, Suneet; Fleming, Mark D.; Williams, David A.

研究方向

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Chafen Lu
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Motomu Shimaoka
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Christopher V. Carman
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Junichi Takagi
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Azucena Salas
H 指数:57论文数:256被引数:1.0万
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Thomas Walz
H 指数:98论文数:411被引数:3.6万
X
Xianchi Dong
H 指数:22论文数:83被引数:2,289
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R. Alon
H 指数:109论文数:610被引数:5.7万
L
Li-Zhi Mi
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Jianghai Zhu
H 指数:17论文数:36被引数:3,239