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Stephen B. Howell

University of California San Diego

83H指数
536论文数
2.3W被引数
收录论文 113
发表时间
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The AKT inhibitor AZD5363 elicits synthetic lethality in ARID1A-deficient gastric cancer cells via induction of pyroptosis
errBRITISH JOURNAL OF CANCER
IF6.8
err2024-07-13
err1
PREAI
errFang, Menghan; Lin, Youfen; Xue, Chaorong; Sheng, Kaiqin; Guo, Zegeng; Han, Yuting; Lin, Hanbin; Wu, Yuecheng; Sang, Yuchao; Chen, Xintan; Howell, Stephen B.; Lin, Xu; Lin, Xinjian
err分享
err收藏
Targeting ARID1A-mutated gastric cancer cells with synthetic lethal approaches
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errFang, Menghan; Lin, Youfen; Xue, Chaorong; Sheng, Kaiqin; Guo, Zegeng; Han, Yuting; Lin, Hanbin; Wu, Yuecheng; Howell, Stephen B.; Lin, Xu; Lin, Xinjian
err分享
err收藏
Therapeutic targeting of LGR5-positive cancer stem cells
errCANCER RESEARCH
IF16.6
err2024-03-22
err0
PREAI
errMulero, Maria Carmen; Rice, Catherine; Jahdav, Sukshala A.; Pi, Willie; Lin, Alexander; Mindy Nguyen; Tai, Owen; Howell, Stephen B.
err分享
err收藏
Exploiting the Receptor-Binding Domains of R-Spondin 1 to Target Leucine-Rich Repeat-Containin G-Coupled Protein Receptor 5-Expressing Stem Cells in Ovarian Cancer S
errJOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
IF3.8
err2023-05-01
err3
errOAAI
errWong, Clara; Mulero, Maria Carmen; Barth, Erika I.; Wang, Katherine; Shang, Xiying; Tikle, Sanika; Rice, Catherine; Gately, Dennis; Howell, Stephen B.
err分享
err收藏
Single-cell characterization of step-wise acquisition of carboplatin resistance in ovarian cancer
errNPJ SYSTEMS BIOLOGY AND APPLICATIONS
IF3.5
err2022-06-17
err3
errOAAI
errWenzel, Alexander T.; Champa, Devora; Venkatesh, Hrishi; Sun, Si; Tsai, Cheng-Yu; Mesirov, Jill P.; Bui, Jack D.; Howell, Stephen B.; Harismendy, Olivier
err分享
err收藏
Luxeptinib (CG-806) Targets FLT3 and Clusters of Kinases Operative in Acute Myeloid Leukemia
errMOLECULAR CANCER THERAPEUTICS
IF5.5
err2022-05-02
err5
errOAAI
errRice, William G.; Howell, Stephen B.; Zhang, Hongying; Rastgoo, Nasrin; Local, Andrea; Kurtz, Stephen E.; Lo, Pierrette; Bottomly, Daniel; Wilmot, Beth; McWeeney, Shannon K.; Druker, Brian J.; Tyner, Jeffrey W.
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Luxeptinib disables NLRP3 inflammasome-mediated IL-1β release and pathways required for secretion of inflammatory cytokines IL-6 and TNFα
errBIOCHEMICAL PHARMACOLOGY
IF5.6
err2022-01-01
err6
errOAAI
errSonowal, Himangshu; Zhang, Hongying; Rice, William; Howell, Stephen B.
err分享
err收藏
Therapeutic Targeting of Tumor Cells Rich in LGR Stem Cell Receptors
errBIOCONJUGATE CHEMISTRY
IF3.9
err2021-01-25
err11
PREAI
errYu, Songman; Mulero, Maria Carmen; Chen, Wannan; Shang, Xiying; Tian, Songyu; Watanabe, Joji; Watanabe, Arisa; Vorberg, Tim; Wong, Clara; Gately, Dennis; Howell, Stephen B.
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err收藏
CG-806, a first-in-class FLT3/BTK inhibitor, and venetoclax synergize to inhibit cell proliferation and to induce apoptosis in aggressive B-cell lymphomas
errCANCER RESEARCH
IF16.6
err2020-08-15
err2
PREAI
errRastgoo, Nasrin; Thayer, Matthew; Benbatoul, Khalid; Howell, Stephen; Rice, William; Zhang, Hongying
err分享
err收藏
A gene set enrichment analysis approach in single-cells along pseudotime trajectories reveals the dynamic activity of oncogenic pathways
errCANCER RESEARCH
IF16.6
err2020-08-15
err0
PREAI
errWenzel, Alexander T.; Champa, Devora; Howell, Stephen B.; Mesirov, Jill P.; Harismendy, Olivier
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err收藏
Neoadjuvant rituximab modulates the tumor immune environment in patients with high risk prostate cancer
errJOURNAL OF TRANSLATIONAL MEDICINE
IF7.5
err2020-05-28
err22
errOAAI
errRyan, Stephen T.; Zhang, Jing; Burner, Danielle N.; Liss, Michael; Pittman, Emily; Muldong, Michelle; Shabaik, Ahmed; Woo, Jason; Basler, Nicole; Cunha, Jonathan; Shalapour, Shabnam; Estrada, Monica, V; Karin, Michael; Messer, Karen; Howell, Stephen; Kane, Christopher J.; Jamieson, Christina A. M.
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err收藏
Securing the Payload, Finding the Cell, and Avoiding the Endosome: Peptide-Targeted, Fusogenic Porous Silicon Nanoparticles for Delivery of siRNA确保有效载荷，找到细胞并避免内体: 用于递送siRNA的肽靶向融合多孔硅纳米颗粒
errADVANCED MATERIALS
IF26.8
err2019-07-03
err89
errOAAI
errKim, Byungji; Sun, Si; Varner, Judith A.; Howell, Stephen B.; Ruoslahti, Erkki; Sailor, Michael J.
err分享
err收藏
CG-806, a pan-FLT3 / pan-BTK inhibitor, demonstrates superior potency against cells from IDH-1 mutant and other non-favorable risk groups of AML patients
errCANCER RESEARCH
IF16.6
err2019-07-01
err0
PREAI
errZhang, Hongying; Local, Andrea; Tyner, Jeffrey W.; Kurtz, Stephen E.; Wilmot, Beth; Mcweeney, Shannon; Druker, Brian J.; Howell, Stephen B.; Rice, William G.
err分享
err收藏
Resistance to APTO-253 caused by internal deletion and alternate promoter usage of the MYC gene in malignant B cells
errCANCER RESEARCH
IF16.6
err2019-07-01
err0
PREAI
errLocal, Andrea; Tsai, Cheng-Yu; Zhang, Hongying; Sheng, Susan; Benbatoul, Khalid; Howell, Stephen B.; Rice, William G.
err分享
err收藏
Tumor-Targeting, MicroRNA-Silencing Porous Silicon Nanoparticles for Ovarian Cancer Therapy肿瘤靶向、微小rna沉默多孔硅纳米颗粒治疗卵巢癌
errACS APPLIED MATERIALS & INTERFACES
IF8.2
err2019-06-17
err65
errOAAI
errBertucci, Alessandro; Kim, Kang-Hoon; Kang, Jinyoung; Zuidema, Jonathan M.; Lee, Seo Hyeon; Kwon, Ester J.; Kim, Dokyoung; Howell, Stephen B.; Ricci, Francesco; Ruoslahti, Erkki; Jang, Hyeung-Jin; Sailor, Michael J.
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Tumor Retention of Enzyme-Responsive Pt(II) Drug-Loaded Nanoparticles Imaged by Nanoscale Secondary Ion Mass Spectrometry and Fluorescence Microscopy
errACS CENTRAL SCIENCE
IF10.4
err2018-10-23
err43
errOAAI
errProetto, Maria T.; Callmann, Cassandra E.; Cliff, John; Szymanski, Craig J.; Hu, Dehong; Howell, Stephen B.; Evans, James E.; Orr, Galya; Gianneschi, Nathan C.
err分享
err收藏
Evolution and characterization of carboplatin resistance at single-cell resolution
errCANCER RESEARCH
IF16.6
err2018-07-01
err0
PREAI
errChampa, Devora; Sun, Si; Tsai, Cheng-Yu; Howell, Stephen; Harismendy, Olivier
err分享
err收藏
APTO-253 is a new addition to the repertoire of drugs that can exploit DNA BRCA1/2 deficiency
errCANCER RESEARCH
IF16.6
err2018-07-01
err0
PREAI
errTsai, Cheng-Yu; Sun, Si; Zhang, Hongying; Local, Andrea; Rice, William; Howell, Stephen B.
err分享
err收藏
CG'806, a first-in-class pan-FLT3/pan-BTK inhibitor, demonstrates superiority to other FLT3 and BTK inhibitors against primary patient samples
errCANCER RESEARCH
IF16.6
err2018-07-01
err1
PREAI
errKurtz, Stephen E.; Watanabe-Smith, Kevin; Bottomly, Dan; Wilmot, Beth; Mcweeney, Shannon; Local, Andrea; Zhang, Hongying; Howell, Stephen; Rice, William; Druker, Brian J.; Tyner, Jeffrey W.
err分享
err收藏
CG′806, a first-in-class pan-FLT3/pan-BTK inhibitor, targets multiple pathways to kill diverse subtypes of acute myeloid leukemia and B-cell malignancy in vitro
errCANCER RESEARCH
IF16.6
err2018-07-01
err3
PREAI
errZhang, Hongying; Local, Andrea; Benbatoul, Khalid; Folger, Peter; Sheng, Susan; Tsai, Cheng-Yu; Howell, Stephen B.; Rice, William G.
err分享
err收藏

研究方向

暂时未获取到该数据
合作学者
合作期刊
M
Michael Karin
H 指数: 254 · 论文数: 904
D
David Mooney
H 指数: 172 · 论文数: 1.7K
E
Erkki Ruoslahti
H 指数: 166 · 论文数: 819
B
Brian Druker
H 指数: 135 · 论文数: 2.6K
J
J. Andrew McCammon
H 指数: 134 · 论文数: 1.1K
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