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收藏Synthesis, in vitro and in vivo biological evaluation of novel dual compounds targeting both acetylcholinesterase and serotonergic 5-HT4 receptors with potential interest in the treatment of Alzheimer's disease
Rochais, Christophe; Lecoutey, Cedric; Lalut, Julien; Davis, Audrey; Duval, Emilie; Gaven, Florence; Largilliere, Stacy; Nee, Gerald; Corvaisier, Sophie; Santos, Jana Sopkova de Oliveira; Since, Marc; Freret, Thomas; Legrand, Romain; Callizot, Noelle; Claeysen, Sylvie; Boulouard, Michel; Dallemagne, Patrick
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收藏A new 3-hit mouse model of schizophrenia built on genetic, early and late factors
Bouet, Valentine; Percelay, Solenn; Leroux, Elise; Diarra, Boubacar; Leger, Marianne; Delcroix, Nicolas; Andrieux, Annie; Dollfus, Sonia; Freret, Thomas; Boulouard, Michel
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收藏Pleiotropic prodrugs: Design of a dual butyrylcholinesterase inhibitor and 5-HT6 receptor antagonist with therapeutic interest in Alzheimer's disease
Toublet, Francois-Xavier; Lalut, Julien; Hatat, Berenice; Lecoutey, Cedric; Davis, Audrey; Since, Marc; Corvaisier, Sophie; Freret, Thomas; Santos, Jana Sopkova-de Oliveira; Claeysen, Sylvie; Boulouard, Michel; Dallemagne, Patrick; Rochais, Christophe
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收藏Donecopride, a Swiss army knife with potential against Alzheimer's disease
Rochais, Christophe; Lecoutey, Cedric; Hamidouche, Katia; Giannoni, Patrizia; Gaven, Florence; Cem, Eleazere; Mignani, Serge; Baranger, Kevin; Freret, Thomas; Bockaert, Joel; Rivera, Santiago; Boulouard, Michel; Dallemagne, Patrick; Claeysen, Sylvie
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收藏Inhibiting Acetylcholinesterase to Activate Pleiotropic Prodrugs with Therapeutic Interest in Alzheimer's Disease
Toublet, Francois-Xavier; Lecoutey, Cedric; Lalut, Julien; Hatat, Berenice; Davis, Audrey; Since, Marc; Corvaisier, Sophie; Freret, Thomas; Santos, Jana Sopkova de Oliveira; Claeysen, Sylvie; Boulouard, Michel; Dallemagne, Patrick; Rochais, Christophe
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收藏A Novel in vivo Anti-amnesic Agent, Specially Designed to Express Both Acetylcholinesterase (AChE) Inhibitory, Serotonergic Subtype 4 Receptor (5-HT4R) Agonist and Serotonergic Subtype 6 Receptor (5-HT6R) Inverse Agonist Activities, With a Potential Interest Against Alzheimer's Disease
Hatat, Berenice; Yahiaoui, Samir; Lecoutey, Cedric; Davis, Audrey; Freret, Thomas; Boulouard, Michel; Claeysen, Sylvie; Rochais, Christophe; Dallemagne, Patrick
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收藏Design, synthesis, and pharmacological evaluation of multitarget-directed ligands with both serotonergic subtype 4 receptor (5-HT4R) partial agonist and 5-HT6R antagonist activities, as potential treatment of Alzheimer's disease
Yahiaoui, Samir; Hamidouche, Katia; Ballandonne, Celine; Davis, Audrey; Santos, Jana Sopkova de Oliveira; Freret, Thomas; Boulouard, Michel; Rochais, Christophe; Dallemagne, Patrick
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收藏Novel Multitarget-Directed Ligands (MTDLs) with Acetylcholinesterase (AChE) Inhibitory and Serotonergic Subtype 4 Receptor (5-HT4R) Agonist Activities As Potential Agents against Alzheimer's Disease: The Design of Donecopride
Rochais, Christophe; Lecoutey, Cedric; Gaven, Florence; Giannoni, Patrizia; Hamidouche, Katia; Hedou, Damien; Dubost, Emmanuelle; Genest, David; Yahiaoui, Samir; Freret, Thomas; Bouet, Valentine; Dauphin, Francois; Santos, Jana Sopkova de Oliveira; Ballandonne, Celine; Corvaisier, Sophie; Malzert-Freon, Aurelie; Legay, Remi; Boulouard, Michel; Claeysen, Sylvie; Dallemagne, Patrick
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