未登录STEM-PD trial protocol: a multi-centre, single-arm, first-in-human, dose-escalation trial, investigating the safety and tolerability of intraputamenal transplantation of human embryonic stem cell-derived dopaminergic cells for Parkinson's diseaseSTEM-PD试验方案：一项多中心、单臂、首个人类、剂量递增试验，旨在研究向豆状核内移植人胚胎干细胞来源的多巴胺能细胞治疗帕金森病的安全性和耐受性。
Paul, Gesine; Bjartmarz, Hjalmar; Bjorklund, Anders; Cutting, Emma; Evans, Amy; Harry, Bronwen; Hansson, Oskar; Kayhanian, Saeed; Kirkeby, Agnete; Lao-Kim, Nicholas; Lindvall, Olle; Nelander, Jenny; Piccini, Paola; Smith, Ruben; Ullen, Susann; Van Vliet, Trinette; Widner, Hakan; Parmar, Malin; Barker, Roger A. .png)
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收藏Human cortical neurons rapidly generated by embryonic stem cell programming integrate into the stroke-injured rat cortex由胚胎干细胞编程快速生成的人皮质神经元整合到中风受损的鼠皮质中。Stem Cells 2025:sxaf049Martinez-Curiel, Raquel; Hajy, Mazin; Tsupykov, Oleg; Jansson, Linda; Avaliani, Natalia; Tampe, Juliane; Monni, Emanuela; Skibo, Galyna; Lindvall, Olle; Palma-Tortosa, Sara; Kokaia, Zaal 分享 收藏 The TransEuro open-label trial of human fetal ventral mesencephalic transplantation in patients with moderate Parkinson's diseaseTransEuro开放标签试验：人类胎儿腹侧中脑移植治疗中度帕金森病患者的临床研究Barker, Roger A.; Lao-Kaim, Nicholas P.; Guzman, Natalie Valle; Athauda, Dilan; Bjartmarz, Hjalmar; Bjoerklund, Anders; Church, Alistair; Cutting, Emma; Daft, Danielle; Dayal, Viswas; Dunnett, Stephen; Evans, Amy; Grealish, Shane; Hannaway, Naomi; He, Xiaoling; Hewitt, Sam; Kefalopoulou, Zinovia; Mahlknecht, Philipp; Martin-Bastida, Antonio; Farrell, Krista; Moore, Sarah; Bulstrode, Harry; Nakornchai, Tagore; Nelander-Wahlestedt, Jenny; Roupe, Linnea; Paul, Gesine; Peall, Kathryn; Rosser, Anne; Roca-Fernandez, Adriana; Rowlands, Sophie; Mcgorrian, Anne-Marie; Scherf, Caroline; Vinh, Ngoc Nga; Roberton, Victoria; Kelly, Claire; Lelos, Mariah; Torres, Eduardo; Shires, Kate; Hills, Rachel; Williams, Debbie; Roussakis, Andreas-Antonios; Sibley, Krista; Tyers, Pamela; Wijeyekoon, Ruwani; Williams-Gray, Caroline; Foltynie, Thomas; Piccini, Paola; Morris, Robert; Lazic, Stanley E.; Lindvall, Olle; Parmar, Malin; Widner, Hakan 分享 收藏 Preclinical quality, safety, and efficacy of a human embryonic stem cell-derived product for the treatment of Parkinson's disease, STEM-PDKirkeby, Agnete; Nelander, Jenny; Hoban, Deirdre B.; Rogelius, Nina; Bjartmarz, Hjalmar; Storm, Petter; Fiorenzano, Alessandro; Adler, Andrew F.; Vale, Shelby; Mudannayake, Janitha; Zhang, Yu; Cardoso, Tiago; Mattsson, Bengt; Landau, Anne M.; Glud, Andreas N.; Sorensen, Jens C.; Lillethorup, Thea P.; Lowdell, Mark; Carvalho, Carla; Bain, Owen; van Vliet, Trinette; Lindvall, Olle; Bjorklund, Anders; Harry, Bronwen; Cutting, Emma; Widner, Hakan; Paul, Gesine; Barker, Roger A.; Parmar, Malin 分享 收藏 Oligodendrocytes in human induced pluripotent stem cell-derived cortical grafts remyelinate adult rat and human cortical neuronsMartinez-Curiel, Raquel; Jansson, Linda; Tsupykov, Oleg; Avaliani, Natalia; Aretio-Medina, Constanza; Hidalgo, Isabel; Monni, Emanuela; Bengzon, Johan; Skibo, Galyna; Lindvall, Olle; Kokaja, Zaal; Palma-Tortosa, Sara 分享 收藏 The need for a standard for informed consent for collection of human fetal materialBarker, Roger A.; Boer, Gerard J.; Cattaneo, Elena; Charo, R. Alta; Lopes, Susana M. Chuva de Sousa; Cong, Yali; Fujita, Misao; Goldman, Steven; Hermeren, Goran; Hyun, Insoo; Lisgo, Steven; Rosser, Anne E.; Anthony, Eric; Lindvall, Olle 分享 收藏 Pericyte-derived fibrotic scarring is conserved across diverse central nervous system lesionsDias, David O.; Kalkitsas, Jannis; Kelahmetoglu, Yildiz; Estrada, Cynthia P.; Tatarishvili, Jemal; Holl, Daniel; Jansson, Linda; Banitalebi, Shervin; Amiry-Moghaddam, Mahmood; Ernst, Aurelie; Huttner, Hagen B.; Kokaia, Zaal; Lindvall, Olle; Brundin, Lou; Frisen, Jonas; Goritz, Christian 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Grafted human pluripotent stem cell-derived cortical neurons integrate into adult human cortical neural circuitryGronning Hansen, Marita; Laterza, Cecilia; Palma-Tortosa, Sara; Kvist, Giedre; Monni, Emanuela; Tsupykov, Oleg; Tornero, Daniel; Uoshima, Naomi; Soriano, Jordi; Bengzon, Johan; Martino, Gianvito; Skibo, Galyna; Lindvall, Olle; Kokaia, Zaal 分享 收藏 Activity in grafted human iPS cell-derived cortical neurons integrated in stroke-injured rat brain regulates motor behavior整合在中风损伤的大鼠大脑中的移植的人iPS细胞源性皮质神经元的活性调节运动行为Palma-Tortosa, Sara; Tornero, Daniel; Hansen, Marita Gronning; Monni, Emanuela; Hajy, Mazin; Kartsivadze, Sopiko; Aktay, Sibel; Tsupykov, Oleg; Parmar, Malin; Deisseroth, Karl; Skibo, Galyna; Lindvall, Olle; Kokaia, Zaal 分享 收藏 分享 收藏 Direct conversion of human fibroblasts to functional excitatory cortical neurons integrating into human neural networksMiskinyte, Giedre; Devaraju, Karthikeyan; Hansen, Marita Gronning; Monni, Emanuela; Tornero, Daniel; Woods, Niels Bjarne; Bengzon, Johan; Ahlenius, Henrik; Lindvall, Olle; Kokaia, Zaal 分享 收藏 分享 收藏 分享 收藏 分享 收藏 分享 收藏 Synaptic inputs from stroke-injured brain to grafted human stem cell-derived neurons activated by sensory stimuliTornero, Daniel; Tsupykov, Oleg; Granmo, Marcus; Rodriguez, Cristina; Gronning-Hansen, Marita; Thelin, Jonas; Smozhanik, Ekaterina; Laterza, Cecilia; Wattananit, Somsak; Ge, Ruimin; Tatarishvili, Jemal; Grealish, Shane; Bruestle, Oliver; Skibo, Galina; Parmar, Malin; Schouenborg, Jens; Lindvall, Olle; Kokaia, Zaal 分享 收藏 Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain在退化的帕金森氏症大脑中移植后24年，广泛的移植物衍生的多巴胺能神经支配得以维持Li, Wen; Englund, Elisabet; Widner, Hakan; Mattsson, Bengt; van Westen, Danielle; Latt, Jimmy; Rehncrona, Stig; Brundin, Patrik; Bjorklund, Anders; Lindvall, Olle; Li, Jia-Yi 分享 收藏 
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