J. Paul Taylor - Publications, H-index & Citations

J. Paul Taylor

st jude childrens research hospital

93H指数

289论文数

6.0W被引数

收录论文 100

发表时间

Shared burden of ultra-rare genetic variants across a spectrum of motor neuron diseases 超罕见遗传变异在一系列运动神经元疾病中的共享负担

Translational Neurodegeneration

IF15.2

2025-10-29

OAAI

Gang Wu; Wenan Chen; Joanne Wuu; Angita Jain; Jason Myers; Isabell Cordts; Evadnie Rampersaud; Jeannine M. Heckmann; Melissa Nel; Volkan Granit; Jeffrey Statland; Andrea Swenson; John Ravits; Corey T. McMillan; Lauren Elman; James Caress; Ted M. Burns; Erik P. Pioro; Jaya Trivedi; Jonathan Katz; Carlayne Jackson; Samuel Maiser; David Walk; Yuen So; Jacob L. McCauley; Matthew C. Baker; J. Paul Taylor; Stephan Zuchner; Rosa Rademakers; Marka van Blitterswijk; Michael Benatar

ASPL couples the assembly of stress granules with their VCP-mediated disassembly ASPL将应力颗粒的组装与其VCP介导的解组装偶联起来。

Science Advances

IF12.5

2025-10-08

PREAI

Gautam Pareek; Dongfang Li; Bo Wang; Jinjun Wu; Brian D. Freibaum; Joseph L. Basalla; Tharun Selvam Mahendran; Anurag Singh; Amanda Nourse; Honghu Quan; Ravi Kalathur; Mitra S. Rana; Brian Maxwell; Yong-Dong Wang; James Messing; Yonghui Ni; Stanley Pounds; Rachayata Dharmat; Jingjun Lu; Xiujie Li-Harms; Alexandre F. Carisey; Shondra M. Pruett-Miller; J. Paul Taylor; Priya Banerjee; Hong Joo Kim; Mondira Kundu

Genetic Associations With an Amyotrophic Lateral Sclerosis Reversal Phenotype

NEUROLOGY

IF8.5

2024-08-27

OAAI

Crayle, Jesse I.; Rampersaud, Evadnie; Myers, Jason R.; Wuu, Joanne; Taylor, J. Paul; Wu, Gang; Benatar, Michael; Bedlack, Richard S.

Cancer-associated DDX3X mutations drive stress granule assembly and impair global translation ( vol 6 , , 2016)

SCIENTIFIC REPORTS

IF3.9

2024-06-06

OAAI

Valentin-Vega, Yasmine A.; Wang, Yong-Dong; Parker, Matthew; Patmore, Deanna M.; Kanagaraj, Anderson; Moore, Jennifer; Rusch, Michael; Finkelstein, David; Ellison, David W.; Gilbertson, Richard J.; Zhang, Jinghui; Kim, Hong Joo; Taylor, J. Paul

Interaction between host G3BP and viral nucleocapsid protein regulates SARS-CoV-2 replication and pathogenicity

CELL REPORTS

IF6.9

2024-03-01

OAAI

Yang, Zemin; Johnson, Bryan A.; Meliopoulos, Victoria A.; Ju, Xiaohui; Zhang, Peipei; Hughes, Michael P.; Wu, Jinjun; Koreski, Kaitlin P.; Clary, Jemma E.; Chang, Ti-Cheng; Wu, Gang; Hixon, Jeff; Duffner, Jay; Wong, Kathy; Lemieux, Rene; Lokugamage, Kumari G.; Alvarado, R. Elias; Crocquet-Valdes, Patricia A.; Walker, David H.; Plante, Kenneth S.; Plante, Jessica A.; Weaver, Scott C.; Kim, Hong Joo; Meyers, Rachel; Schultz-Cherry, Stacey; Ding, Qiang; Menachery, Vineet D.; Taylor, J. Paul

Identification of small molecule inhibitors of G3BP-driven stress granule formation G3BP-driven应力颗粒形成小分子抑制剂的鉴定

JOURNAL OF CELL BIOLOGY

IF6.4

2024-01-29

OAAI

Freibaum, Brian D.; Messing, James; Nakamura, Haruko; Yurtsever, Ugur; Wu, Jinjun; Kim, Hong Joo; Hixon, Jeff; Lemieux, Rene Marc; Duffner, Jay; Huynh, Walter; Wong, Kathy; White, Michael; Lee, Christina; Meyers, Rachel E.; Parker, Roy; Taylor, J. Paul

Selective modulation of the androgen receptor AF2 domain rescues degeneration in spinal bulbar muscular atrophy (vol 24, pg 427, 2018)

NATURE MEDICINE

IF50

2024-01-08

OAAI

Badders, Nisha M.; Korff, Ane; Miranda, Helen C.; Vuppala, Pradeep K.; Smith, Rebecca B.; Winborn, Brett J.; Quemin, Emmanuelle R.; Sopher, Bryce L.; Dearman, Jennifer; Messing, James; Kim, Nam Chul; Moore, Jennifer; Freibaum, Brian D.; Kanagaraj, Anderson P.; Fan, Baochang; Tillman, Heather; Chen, Ping-Chung; Wang, Yingzhe; Freeman III, Burgess B.; Li, Yimei; Kim, Hong Joo; La Spada, Albert R.; Taylor, J. Paul

Using the structural diversity of RNA: protein interfaces to selectively target RNA with small molecules in cells: methods and perspectives 利用RNA的结构多样性: 蛋白质界面选择性靶向RNA与细胞中的小分子: 方法和观点

FRONTIERS IN MOLECULAR BIOSCIENCES

IF4

2023-11-16

OAAI

Li, Aixiao; Bouhss, Ahmed; Clement, Marie-Jeanne; Bauvais, Cyril; Taylor, J. Paul; Bollot, Guillaume; Pastre, David

Senataxin helicase, the causal gene defect in ALS4, is a significant modifier of C9orf72 ALS G4C2 and arginine-containing dipeptide repeat toxicity

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2023-10-17

OAAI

Bennett, Craig L.; Dastidar, Somasish; Arnold, Frederick J.; McKinstry, Spencer U.; Stockford, Cameron; Freibaum, Brian D.; Sopher, Bryce L.; Wu, Meilin; Seidner, Glen; Joiner, William; Taylor, J. Paul; West, Ryan J. H.; La Spada, Albert R.

Analysis of Structural Variants Previously Associated With ALS in Europeans Highlights Genomic Architectural Differences in Africans

NEUROLOGY-GENETICS

IF3.7

2023-08-01

OAAI

Monnakgotla, Nomakhosazana R.; Mahungu, Amokelani C.; Heckmann, Jeannine M.; Botha, Gerrit; Mulder, Nicola J.; Wu, Gang; Rampersaud, Evadnie; Myers, Jason; Van Blitterswijk, Marka; Rademakers, Rosa; Taylor, J. Paul; Wuu, Joanne; Benatar, Michael; Nel, Melissa

A murine model of hnRNPH2-related neurodevelopmental disorder reveals a mechanism for genetic compensation by Hnrnph1

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2023-07-17

OAAI

Korff, Ane; Yang, Xiaojing; O'Donovan, Kevin; Gonzalez, Abner; Teubner, Brett J. W.; Nakamura, Haruko; Messing, James; Yang, Fen; Carisey, Alexandre F.; Wang, Yong-Dong; Patni, Tushar; Sheppard, Heather; Zakharenko, Stanislav S.; Chook, Yuh Min; Taylor, J. Paul; Kim, Hong Joo

MAP4K3 inhibits Sirtuin-1 to repress the LKB1-AMPK pathway to promote amino acid-dependent activation of the mTORC1 complex

LIFE SCIENCE ALLIANCE

IF2.9

2023-05-23

OAAI

Branch, Mary Rose; Hsu, Cynthia L.; Ohnishi, Kohta; Shen, Wen-Chuan; Lee, Elian; Meisenhelder, Jill; Winborn, Brett; Sopher, Bryce L.; Taylor, J. Paul; Hunter, Tony; La Spada, Albert R.

Selective Accumulation of Aggregation-Prone Proteasome Substrates in Response to Proteotoxic Stress 对蛋白毒性应激的选择性积累易于聚集的蛋白酶体底物

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

OAAI

Salomons, Florian A.; Menendez-Benito, Victoria; Bottcher, Claudia; McCray, Brett A.; Taylor, J. Paul; Dantuma, Nico P.

Effects of Mutations on the Aggregation Propensity of the Human Prion-Like Protein hnRNPA2B1

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-17

OAAI

Paul, Kacy R.; Molliex, Amandine; Cascarina, Sean; Boncella, Amy E.; Taylor, J. Paul; Ross, Eric D.

Heterozygous frameshift variants in HNRNPA2B1 cause early-onset oculopharyngeal muscular dystrophy

NATURE COMMUNICATIONS

IF15.7

2022-04-28

OAAI

Kim, Hong Joo; Mohassel, Payam; Donkervoort, Sandra; Guo, Lin; O'Donovan, Kevin; Coughlin, Maura; Lornage, Xaviere; Foulds, Nicola; Hammans, Simon R.; Foley, A. Reghan; Fare, Charlotte M.; Ford, Alice F.; Ogasawara, Masashi; Sato, Aki; Iida, Aritoshi; Munot, Pinki; Ambegaonkar, Gautam; Phadke, Rahul; O'Donovan, Dominic G.; Buchert, Rebecca; Grimmel, Mona; Topf, Ana; Zaharieva, Irina T.; Brady, Lauren; Hu, Ying; Lloyd, Thomas E.; Klein, Andrea; Steinlin, Maja; Kuster, Alice; Mercier, Sandra; Marcorelles, Pascale; Pereon, Yann; Fleurence, Emmanuelle; Manzur, Adnan; Ennis, Sarah; Upstill-Goddard, Rosanna; Bello, Luca; Bertolin, Cinzia; Pegoraro, Elena; Salviati, Leonardo; French, Courtney E.; Shatillo, Andriy; Raymond, F. Lucy; Haack, Tobias; Quijano-Roy, Susana; Bohm, Johann; Nelson, Isabelle; Stojkovic, Tanya; Evangelista, Teresinha; Straub, Volker; Romero, Norma B.; Laporte, Jocelyn; Muntoni, Francesco; Nishino, Ichizo; Tarnopolsky, Mark A.; Shorter, James; Bonnemann, Carsten G.; Taylor, J. Paul

Revealing the Mutational Spectrum in Southern Africans With Amyotrophic Lateral Sclerosis

NEUROLOGY-GENETICS

IF3.7

2022-02-01

OAAI

Nel, Melissa; Mahungu, Amokelani C.; Monnakgotla, Nomakhosazana; Botha, Gerrit R.; Mulder, Nicola J.; Wu, Gang; Rampersaud, Evadnie; van Blitterswijk, Marka; Wuu, Joanne; Cooley, Anne; Myers, Jason; Rademakers, Rosa; Taylor, J. Paul; Benatar, Michael; Heckmann, Jeannine M.

Pathological phase transitions in ALS-FTD impair dynamic RNA-protein granules ALS-FTD的病理相变损害动态RNA-蛋白质颗粒

RNA

IF5

2021-10-27

OAAI

Nedelsky, Natalia B.; Taylor, J. Paul

Characterization of HNRNPA1 mutations defines diversity in pathogenic mechanisms and clinical presentation

JCI INSIGHT

IF6.1

2021-07-22

OAAI

Beijer, Danique; Kim, Hong Joo; Guo, Lin; O'Donovan, Kevin; Mademan, Ines; Deconinck, Tine; Van Schil, Kristof; Fare, Charlotte M.; Drake, Lauren E.; Ford, Alice F.; Kochanski, Andrzej; Kabzinska, Dagmara; Dubuisson, Nicolas; Van den Bergh, Peter; Voermans, Nicol C.; Lemmers, Richard J. L. F.; van der Maarel, Silvere M.; Bonner, Devon; Sampson, Jacinda B.; Wheeler, Matthew T.; Mehrabyan, Anahit; Palmer, Steven; De Jonghe, Peter; Shorter, James; Taylor, J. Paul; Baets, Jonathan

TDP-43 and PINK1 mediate CHCHD10S59L mutation-induced defects in Drosophila and in vitro (vol 12, 1924, 2021)

NATURE COMMUNICATIONS

IF15.7

2021-05-20

OAAI

Baek, Minwoo; Choe, Yun-Jeong; Bannwarth, Sylvie; Kim, JiHye; Maitra, Swati; Dorn, Gerald W., II; Taylor, J. Paul; Paquis-Flucklinger, Veronique; Kim, Nam Chul

Rare Inherited forms of Paget's Disease and Related Syndromes (vol 104, pg 501, 2019)

CALCIFIED TISSUE INTERNATIONAL

IF3.2

2021-04-19

OAAI

Ralston, Stuart H.; Taylor, J. Paul

研究方向