Michael R. Knowles - Publications, H-index & Citations

Michael R. Knowles

University of North Carolina School of Medicine

99H指数

517论文数

3.6W被引数

收录论文 122

发表时间

Cells 2025, Vol. 14, Page 1460

IF5.2

2025-09-20

OAAI

Marie-Hélène Bourassa; Guillaume Sillon; Shuizi Ding; Maurizio Chioccioli; Monkol Lek; Kaiyue Ma; Alejandro Mejia-Garcia; Simon Gravel; Donald C. Vinh; Michael R. Knowles; Margaret W. Leigh; Stephanie D. Davis; Thomas Ferkol; Kenneth N. Olivier; Elizabeth N. Schecterman; Weining Yin; Patrick R. Sears; Martina Gentzsch; Susan E. Boyles; William D. Bennett; Kirby L. Zeman; Lawrence E. Ostrowski; Maimoona A. Zariwala; Adam J. Shapiro

Airway Disease Progression on Chest Computed Tomography in Children With Primary Ciliary Dyskinesia 儿童原发性纤毛运动障碍患者胸部计算机断层扫描中的气道病变进展

Pediatric Pulmonology

IF2.3

2025-09-18

PREAI

BreAnna Kinghorn; Federico Mollica; Daan Caudri; Stephanie D. Davis; Sharon Dell; Thomas W. Ferkol; Robert Andrew Gardner; Michael R. Knowles; Carlos Milla; Jessica E. Pittman; Margaret Rosenfeld; Scott D. Sagel; Adam J. Shapiro; Erin Sullivan; Kelli M. Sullivan; Harm A. W. M. Tiddens; Maimoona A. Zariwala; Margaret W. Leigh; for the Genetic Disorders of Mucociliary Clearance Consortium

Overlapping Clinical Phenotypes in Patients with Primary Ciliary Dyskinesia or Activated Phosphoinositide 3-Kinase Delta Syndrome

JOURNAL OF PEDIATRICS

IF3.5

2025-05-01

PREAI

Shapiro, Adam J.; Wu, Eveline Y.; Morris-Rosendahl, Deborah J.; Olivier, Kenneth N.; Dell, Sharon D.; Sagel, Scott D.; Dutmer, Cullen M.; Mosquera, Ricardo A.; Rose, Markus; O'Connor, Michael G.; Ma, Chi A.; Uzel, Gulbu; Vece, Timothy J.; Zariwala, Maimoona A.; Knowles, Michael R.; Leigh, Margaret W.; Davis, Stephanie D.; Ferkol, Thomas W.

Long G4-rich enhancers target promoters via a G4 DNA-based mechanism

NUCLEIC ACIDS RESEARCH

IF13.1

2024-12-10

OAAI

Demeis, Jeffrey D.; Roberts, Justin T.; Delcher, Haley A.; Godang, Noel L.; Coley, Alexander B.; Brown, Cana L.; Shaw, Michael H.; Naaz, Sayema; Dahal, Ayush; Alqudah, Shahem Y.; Nguyen, Kevin N.; Nguyen, Anita D.; Paudel, Sunita S.; Shell, John E.; Patil, Suhas S.; Dang, Hong; O'Neal, Wanda K.; Knowles, Michael R.; Houserova, Dominika; Gillespie, Mark N.; Borchert, Glen M.

Late Breaking Abstract - Recessively inherited deficiency of secreted WFDC2 (HE4) causes nasal polyposis and bronchiectasis 晚期研究摘要-分泌型WFDC2 (HE4) 隐性遗传缺陷导致鼻息肉和支气管扩张

EUROPEAN RESPIRATORY JOURNAL

IF21

2024-10-30

PREAI

Dougherty, Gerard; Ostrowski, Lawrence E.; Noethe-Menchen, Tabea; Raidt, Johanna; Schramm, Andre; Olbrich, Heike; Yin, Weining; Sears, Patrick R.; Dang, Hong; Smith, Amanda J.; Beule, Achim G.; Hjeij, Rim; Rutjes, Niels; Haarman, Eric G.; Maas, Saskia M.; Ferkol, Thomas W.; Noone, Peadar G.; Olivier, Kenneth N.; Bracht, Diana C.; Barbry, Pascal; Zaragosi, Laure-Emmanuelle; Fierville, Morgane; Kliesch, Sabine; Wohlgemuth, Kai; Koenig, Julia; George, Sebastian; Loges, Niki; Ceppe, Agathe; Markovetz, Matthew R.; Luo, Hong; Guo, Ting; Rizk, Hoda; Eldesoky, Tarek; Dahlke, Katrin; Boldt, Karsten; Ueffing, Marius; Hill, David B.; Pang, Yuan-Ping; Knowles, Michael R.; Zariwala, Maimoona A.; Omran, Heymut

Genetic modifiers of body mass index in individuals with cystic fibrosis

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2024-10-01

PREAI

Ling, Hua; Raraigh, Karen S.; Pugh, Elizabeth W.; Aksit, Melis A.; Zhang, Peng; Pace, Rhonda G.; Faino, Anna, V; Bamshad, Michael J.; Gibson, Ronald L.; O'Neal, Wanda; Knowles, Michael R.; Blackman, Scott M.; Cutting, Garry R.

The clinical utility of sequencing the entirety of CFTR

JOURNAL OF CYSTIC FIBROSIS

IF6

2024-07-01

PREAI

Sheridan, Molly B.; Aksit, Melis A.; Pagel, Kymberleigh; Hetrick, Kurt; Shultz-Lutwyche, Hannah; Myers, Ben; Buckingham, Kati J.; Pace, Rhonda G.; Ling, Hua; Pugh, Elizabeth; O'Neal, Wanda K.; Bamshad, Michael J.; Gibson, Ronald L.; Knowles, Michael R.; Blackman, Scott M.; Cutting, Garry R.; Raraigh, Karen S.

Situs Ambiguus Is Associated With Adverse Clinical Outcomes in Children With Primary Ciliary Dyskinesia Situs歧义与原发性睫状运动障碍儿童的不良临床结局相关

CHEST

IF8.6

2024-05-01

PREAI

Kaspy, Kimberley R.; Dell, Sharon D.; Davis, Stephanie D.; Ferkol, Thomas W.; Rosenfeld, Margaret; Sagel, Scott D.; Milla, Carlos; Olivier, Kenneth N.; Barber, Andrew T.; Wee, Wallace; Lin, Feng-Chang; Li, Lang; Rampakakis, Emmanouil; Zariwala, Maimoona A.; Knowles, Michael R.; Leigh, Margaret W.; Shapiro, Adam J.

MagicalRsq-X: A cross-cohort transferable genotype imputation quality metric Magicalrsq-x: 一种跨队列可转移基因型归约质量指标

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2024-05-01

PREAI

Sun, Quan; Yang, Yingxi; Rosen, Jonathan D.; Chen, Jiawen; Li, Xihao; Guan, Wyliena; Jiang, Min-Zhi; Wen, Jia; Pace, Rhonda G.; Blackman, Scott M.; Bamshad, Michael J.; Gibson, Ronald L.; Cutting, Garry R.; O'Neal, Wanda K.; Knowles, Michael R.; Kooperberg, Charles; Reiner, Alexander P.; Raffield, Laura M.; Carson, April P.; Rich, Stephen S.; Rotter, Jerome I.; Loos, Ruth J. F.; Kenny, Eimear; Jaeger, Byron C.; Min, Yuan -, I; Fuchsberger, Christian; Li, Yun

Recessively Inherited Deficiency of Secreted WFDC2 (HE4) Causes Nasal Polyposis and Bronchiectasis

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2024-04-16

OAAI

Dougherty, Gerard W.; Ostrowski, Lawrence E.; Noethe-Menchen, Tabea; Raidt, Johanna; Schramm, Andre; Olbrich, Heike; Yin, Weining; Sears, Patrick R.; Dang, Hong; Smith, Amanda J.; Beule, Achim G.; Hjeij, Rim; Rutjes, Niels; Haarman, Eric G.; Maas, Saskia M.; Ferkol, Thomas W.; Noone, Peadar G.; Olivier, Kenneth N.; Bracht, Diana C.; Barbry, Pascal; Zaragosi, Laure-Emmanuelle; Fierville, Morgane; Kliesch, Sabine; Wohlgemuth, Kai; Koenig, Julia; George, Sebastian; Loges, Niki T.; Ceppe, Agathe; Markovetz, Matthew R.; Luo, Hong; Guo, Ting; Rizk, Hoda; Eldesoky, Tarek; Dahlke, Katrin; Boldt, Karsten; Ueffing, Marius; Hill, David B.; Pang, Yuan-Ping; Knowles, Michael R.; Zariwala, Maimoona A.; Omran, Heymut

Genetic variation in severe cystic fibrosis liver disease is associated with novel mechanisms for disease pathogenesis

HEPATOLOGY

IF15.8

2024-03-27

PREAI

Stonebraker, Jaclyn; Pace, Rhonda; Gallins, Paul; Dang, Hong; Aksit, Melis; Faino, Anna; Gordon, William; Macparland, Sonya; Bamshad, Michael; Gibson, Ronald; Cutting, Garry; Durie, Peter; Wright, Fred; Zhou, Yi-Hui; Blackman, Scott; O'Neal, Wanda; Ling, Simon; Knowles, Michael

Safety and efficacy of the epithelial sodium channel blocker idrevloride in people with primary ciliary dyskinesia (CLEAN-PCD): a multinational, phase 2, randomised, double- blind, placebo-controlled crossover trial

LANCET RESPIRATORY MEDICINE

IF32.8

2024-01-01

PREAI

Ringshausen, Felix C.; Shapiro, Adam J.; Nielsen, Kim G.; Mazurek, Henryk; Pifferi, Massimo; Donn, Karl H.; van der Eerden, Menno M.; Loebinger, Michael R.; Zariwala, Maimoona A.; Leigh, Margaret W.; Knowles, Michael R.; Ferkol, Thomas W.

RCT Abstract - Safety and efficacy of idrevloride in people with primary ciliary dyskinesia: a double-blind, randomized, placebo-controlled crossover trial (CLEAN-PCD)

EUROPEAN RESPIRATORY JOURNAL

IF21

2023-10-27

PREAI

Ringshausen, Felix C.; Shapiro, Adam J.; Nielsen, Kim G.; Mazurek, Henryk; Pifferi, Massimo; Donn, Karl H.; Van Der Eerden, Menno M.; Loebinger, Michael R.; Zariwala, Maimoona A.; Leigh, Margaret W.; Knowles, Michael R.; Ferkol, Thomas W.

Genetic Modifiers of Cystic Fibrosis Lung Disease Severity 囊性纤维化肺疾病严重程度的遗传调节剂

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

IF19.4

2023-05-15

PREAI

Zhou, Yi-Hui; Gallins, Paul J.; Pace, Rhonda G.; Dang, Hong; Aksit, Melis A.; Blue, Elizabeth E.; Buckingham, Kati J.; Collaco, Joseph M.; Faino, Anna V.; Gordon, William W.; Hetrick, Kurt N.; Ling, Hua; Liu, Weifang; Onchiri, Frankline M.; Pagel, Kymberleigh; Pugh, Elizabeth W.; Raraigh, Karen S.; Rosenfeld, Margaret; Sun, Quan; Wen, Jia; Li, Yun; Corvol, Harriet; Strug, Lisa J.; Bamshad, Michael J.; Blackman, Scott M.; Cutting, Garry R.; Gibson, Ronald L.; O'Neal, Wanda K.; Wright, Fred A.; Knowles, Michael R.

Airway Disease in Children with Primary Ciliary Dyskinesia Impact of Ciliary Ultrastructure Defect and Genotype

ANNALS OF THE AMERICAN THORACIC SOCIETY

IF5.4

2023-04-01

PREAI

Kinghorn, BreAnna; Rosenfeld, Margaret; Sullivan, Erin; Onchiri, Frankline; Ferkol, Thomas W.; Sagel, Scott D.; Dell, Sharon D.; Milla, Carlos; Shapiro, Adam J.; Sullivan, Kelli M.; Zariwala, Maimoona A.; Pittman, Jessica E.; Mollica, Federico; Tiddens, Harm A. W. M.; Kemner-van De Corput, Mariette; Knowles, Michael R.; Davis, Stephanie D.; Leigh, Margaret W.

The inequitable exposure of socially vulnerable groups to water shortages across the United States 社会弱势群体对美国水资源短缺的不公平暴露

ENVIRONMENTAL RESEARCH LETTERS

IF5.6

2023-03-31

OAAI

Sanchez, Leslie; Warziniack, Travis; Knowles, Michael

Laterality Defects in Primary Ciliary Dyskinesia Relationship to Ultrastructural Defect or Genotype

ANNALS OF THE AMERICAN THORACIC SOCIETY

IF5.4

2023-03-01

OAAI

Barber, Andrew T.; Shapiro, Adam J.; Davis, Stephanie D.; Ferkol, Thomas W.; Atkinson, Jeffrey J.; Sagel, Scott D.; Dell, Sharon D.; Olivier, Kenneth N.; Milla, Carlos E.; Rosenfeld, Margaret; Li, Lang; Lin, Feng-Chang; Sullivan, Kelli M.; Capps, Nicole A.; Zariwala, Maimoona A.; Knowles, Michael R.; Leigh, Margaret W.

Airway Inflammation in Children with Primary Ciliary Dyskinesia

ANNALS OF THE AMERICAN THORACIC SOCIETY

IF5.4

2023-01-01

OAAI

Sagel, Scott D.; Kupfer, Oren; Wagner, Brandie D.; Davis, Stephanie D.; Dell, Sharon D.; Ferkol, Thomas W.; Hoppe, Jordana E.; Rosenfeld, Margaret; Sullivan, Kelli M.; Tiddens, Harm A. W. M.; Knowles, Michael R.; Leigh, Margaret W.

MagicalRsq: Machine-learning-based genotype imputation quality calibration MagicalRsq: 基于机器学习的基因型归因质量校准

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2022-11-01

OAAI

Sun, Quan; Yang, Yingxi; Rosen, Jonathan D.; Jiang, Min-Zhi; Chen, Jiawen; Liu, Weifang; Wen, Jia; Raffield, Laura M.; Pace, Rhonda G.; Zhou, Yi-Hui; Wright, Fred A.; Blackman, Scott M.; Bamshad, Michael J.; Gibson, Ronald L.; Cutting, Garry R.; Knowles, Michael R.; Schrider, Daniel R.; Fuchsberger, Christian; Li, Yun

Association of Neonatal Hospital Length of Stay with Lung Function in Primary Ciliary Dyskinesia

ANNALS OF THE AMERICAN THORACIC SOCIETY

IF5.4

2022-11-01

OAAI

Wee, Wallace B.; Leigh, Margaret W.; Davis, Stephanie D.; Rosenfeld, Margaret; Sullivan, Kelli M.; Sawras, Michael G.; Ferkol, Thomas W.; Knowles, Michael R.; Milla, Carlos; Sagel, Scott D.; Zariwala, Maimoona A.; Pullenayegum, Eleanor; Dell, Sharon D.

研究方向