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收藏BTK regulates microglial function and neuroinflammation in human stem cell models and mouse models of multiple sclerosis
Gruber, Ross C.; Wirak, Gregory S.; Blazier, Anna S.; Lee, Lan; Dufault, Michael R.; Hagan, Nellwyn; Chretien, Nathalie; LaMorte, Michael; Hammond, Timothy R.; Cheong, Agnes; Ryan, Sean K.; Macklin, Andrew; Zhang, Mindy; Pande, Nilesh; Havari, Evis; Turner, Timothy J.; Chomyk, Anthony; Christie, Emilie; Trapp, Bruce D.; Ofengeim, Dimitry
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收藏Transcript Profiles of Microglia/Macrophage Cells at the Borders of Chronic Active and Subpial Gray Matter Lesions in Multiple Sclerosis
Chomyk, Anthony; Kucinski, Rikki; Kim, Jihye; Christie, Emilie; Cyncynatus, Kaitlyn; Gossman, Zachary; Chen, Zhihong; Richardson, Brian; Cameron, Mark; Turner, Tim; Dutta, Ranjan; Trapp, Bruce
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收藏p38γ MAPK delays myelination and remyelination and is abundant in multiple sclerosis lesions
Marziali, Leandro N.; Hwang, Yoonchan; Palmisano, Marilena; Cuenda, Ana; Sim, Fraser J.; Gonzalez, Alberto; Volsko, Christina; Dutta, Ranjan; Trapp, Bruce D.; Wrabetz, Lawrence; Feltri, Maria L.
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收藏Neuroprotection by Preconditioning in Mice is Dependent on MyD88-Mediated CXCL10 Expression in Endothelial Cells
Chen, Zhihong; Hu, Weiwei; Mendez, Mynor J.; Gossman, Zachary C.; Chomyk, Anthony; Boylan, Brendan T.; Kidd, Grahame J.; Phares, Timothy W.; Bergmann, Cornelia C.; Trapp, Bruce D.
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收藏Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis
Licht-Mayer, Simon; Campbell, Graham R.; Mehta, Arpan R.; McGill, Katie; Symonds, Alex; Al-Azki, Sarah; Pryce, Gareth; Zandee, Stephanie; Zhao, Chao; Kipp, Markus; Smith, Kenneth J.; Baker, David; Altmann, Daniel; Anderton, Stephen M.; Kap, Yolanda S.; Laman, Jon D.; Bert, A.; Rodriguez, Moses; Franklin, Robin J. M.; Chandran, Siddharthan; Lassmann, Hans; Trapp, Bruce D.; Mahad, Don J.
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收藏Single-Nucleus RNA-seq of Normal-Appearing Brain Regions in Relapsing-Remitting vs. Secondary Progressive Multiple Sclerosis: Implications for the Efficacy of Fingolimod
Kihara, Yasuyuki; Zhu, Yunjiao; Jonnalagadda, Deepa; Romanow, William; Palmer, Carter; Siddoway, Benjamin; Rivera, Richard; Dutta, Ranjan; Trapp, Bruce D.; Chun, Jerold
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收藏Inflammation-dependent oxidative stress metabolites as a hallmark of amyotrophic lateral sclerosis
Xiong, Luyang; McCoy, Michael; Komuro, Hitoshi; West, Xiaoxia Z.; Yakubenko, Valentin; Gao, Detao; Dudiki, Tejasvi; Milo, Amanda; Chen, Jacqueline; Podrez, Eugene A.; Trapp, Bruce; Byzova, Tatiana, V
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收藏Juxtacortical susceptibility changes in progressive multifocal leukoencephalopathy at the gray-white matter junction correlates with iron-enriched macrophages
Mahajan, Kedar R.; Amin, Moein; Poturalski, Matthew; Lee, Jonathan; Herman, Danielle; Zheng, Yufan; Androjna, Caroline; Howell, Mark; Fox, Robert J.; Trapp, Bruce D.; Jones, Stephen E.; Nakamura, Kunio; Ontaneda, Daniel
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收藏Microglial Displacement of GABAergic Synapses Is a Protective Event during Complex Febrile SeizuresGaba能突触的小胶质细胞移位是复杂高热惊厥期间的保护性事件
Wan, Yushan; Feng, Bo; You, Yi; Yu, Jie; Xu, Cenglin; Dai, Haibin; Trapp, Bruce D.; Shi, Peng; Chen, Zhong; Hu, Weiwei
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收藏Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis
Licht-Mayer, Simon; Campbell, Graham R.; Canizares, Marco; Mehta, Arpan R.; Gane, Angus B.; McGill, Katie; Ghosh, Aniket; Fullerton, Alexander; Menezes, Niels; Dean, Jasmine; Dunham, Jordon; Al-Azki, Sarah; Pryce, Gareth; Zandee, Stephanie; Zhao, Chao; Kipp, Markus; Smith, Kenneth J.; Baker, David; Altmann, Daniel; Anderton, Stephen M.; Kap, Yolanda S.; Laman, Jon D.; 't Hart, Bert A.; Rodriguez, Moses; Watzlawick, Ralf; Schwab, Jan M.; Carter, Roderick; Morton, Nicholas; Zagnoni, Michele; Franklin, Robin J. M.; Mitchell, Rory; Fleetwood-Walker, Sue; Lyons, David A.; Chandran, Siddharthan; Lassmann, Hans; Trapp, Bruce D.; Mahad, Don J.
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