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Chromatin activity of IκBα mediates the exit from naive pluripotency Palma, Luis G.; Alvarez-Villanueva, Daniel; Maqueda, Maria; Barrero, Mercedes; Iglesias, Arnau; Bertran, Joan; Alvarez, Damiana; Garcia-Prieto, Carlos A.; Ballare, Cecilia; Rodriguez-Cortez, Virginia; Bueno, Clara; Vidal, August; Villanueva, Alberto; Menendez, Pablo; Stik, Gregoire; Di Croce, Luciano; Payer, Bernhard; Esteller, Manel; Espinosa, Lluis; Bigas, Anna 分享 收藏
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CD22 CAR-T cells secreting CD19 T-cell engagers for improved control of B-cell acute lymphoblastic leukemia progression 分泌CD19 T细胞结合剂的CD22 CAR-T细胞，用于改善B细胞急性淋巴细胞白血病进展的控制 Arroyo-Rodenas, Javier; Falgas, Aida; Diez-Alonso, Laura; Martinez-Moreno, Alba; Roca-Ho, Heleia; Gil-Etayo, Francisco J.; Perez-Pons, Alba; Aguilar-Sopena, Oscar; Velasco-Sidro, Miriam; Gomez-Rosel, Marina; Jimenez-Matias, Beatriz; Munoz-Sanchez, Guillermo; Pacheco, Yedra; Bravo-Martin, Clara; Ramirez-Fernandez, Angel; Jimenez-Reinoso, Anais; Gonzalez-Navarro, Europa Azucena; Juan, Manel; Orfao, Alberto; Blanco, Belen; Roda-Navarro, Pedro; Bueno, Clara; Menendez, Pablo; Alvarez-Vallina, Luis 分享 收藏
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LILRB1-directed CAR-T cells for the treatment of hematological malignancies LILRB1靶向CAR-T细胞用于治疗血液系统恶性肿瘤 Marhelava, Katsiaryna; Fidyt, Klaudyna; Pepek, Monika; Krawczyk, Marta; Forcados, Christopher; Malinowska, Agata; Swiderska, Bianka; Fernandez-Fuentes, Narcis; Czerwik, Natalia; Baranowska, Iwona; Krzywdzinska, Agnieszka; Sedek, Lukasz; Slota, Lukasz; Perkowski, Bartosz; Villatoro, Alicia; Leray, Thibault; Lech-Maranda, Ewa; Menendez, Pablo; Inderberg, Else Marit; Walchli, Sebastien; Winiarska, Magdalena; Firczuk, Malgorzata 分享 收藏
Proteins of the cancer cell secretome induce the protumoral microenvironment of diffuse intrinsic pontine glioma 癌症细胞分泌蛋白诱导弥漫性内生性脑桥胶质瘤的促肿瘤微环境 Baulenas-Farres, Merce; Paco, Sonia; Marino, Federica; Mohr, Jacqueline; Panisello, Carla; Balaguer-Lluna, Leire; Aschero, Rosario; Cuadrado-Vilanova, Maria; Resa-Pares, Claudia; Rodriguez, Eva; Marquez, Jesus; Menendez, Pablo; Jou, Cristina; Benitez, Raul; Benitez-Ribas, Daniel; Lavarino, Cinzia; Mora, Jaume; Carcaboso, Angel M. 分享 收藏
A novel human pluripotent stem cell gene activation system identifies IGFBP2 as a mediator in the production of haematopoietic progenitors in vitro 一种新型的人类多能干细胞基因激活系统将IGFBP2鉴定为体外造血祖细胞产生的介体 Petazzi, Paolo; Ventura, Telma; Luongo, Francesca Paola; McClafferty, Heather; May, Alisha; Taylor, Helen Alice; Shipston, Michael J.; Romano, Nicola; Forrester, Lesley M.; Menendez, Pablo; Fidanza, Antonella 分享 收藏
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Integrative single-cell multi-omics of CD19-CARpos and CARneg T cells suggest drivers of immunotherapy response in B cell neoplasias CD19-CARpos和CARneg T细胞的整合单细胞多组学提示b细胞肿瘤中免疫治疗反应的驱动因素 Guerrero-Murillo, Mercedes; Rill-Hinarejos, Aina; Trincado, Juan L.; Bataller, Alex; Ortiz-Maldonado, Valentin; Benitez-Ribas, Daniel; Espanol-Rego, Marta; Gonzalez-Navarro, Eazucena; Martinez-Cibrian, Nuria; Marchese, Domenica; Martin-Martin, Lourdes; Garcia-Sancho, Alejandro Martin; Rives, Susana; Heyn, Holger; Juan, Manel; Urbano-Ispizua, Alvaro; Delgado, Julio; Orfao, Alberto; Mereu, Elisabetta; Bueno, Clara; Menendez, Pablo 分享 收藏
NSGS mice humanized with cord blood mononuclear cells show sustained and functional myeloid-lymphoid representation with limited graft-versus-host disease Panisello, Carla; Aschero, Rosario; Martinez-Moreno, Alba; Ho, Heleia Roca; Falgas, Aida; Gonzalez-Navarro, Europa Azucena; Carabelli, Julieta; Pradenas, Edwards; Lazaro-Diez, Maria; Prado, Julia G.; Blanco, Julia; Carrillo, Jorge; Juan, Manel; Carcaboso, Angel M.; Bueno, Clara; Menendez, Pablo 分享 收藏
RNA sequestration in P-bodies sustains myeloid leukaemia P体中的RNA隔离维持了髓性白血病 Kodali, Srikanth; Proietti, Ludovica; Valcarcel, Gemma; Lopez-Rubio, Anna V.; Pessina, Patrizia; Eder, Thomas; Shi, Junchao; Jen, Annie; Lupion-Garcia, Nuria; Starner, Anne C.; Bartels, Mason D.; Cui, Yingzhi; Sands, Caroline M.; Planas-Riverola, Ainoa; Martinez, Alba; Velasco-Hernandez, Talia; Tomas-Daza, Laureano; Alber, Bernhard; Manhart, Gabriele; Mayer, Isabella Maria; Kollmann, Karoline; Fatica, Alessandro; Menendez, Pablo; Shishkova, Evgenia; Rau, Rachel E.; Javierre, Biola M.; Coon, Joshua; Chen, Qi; Van Nostrand, Eric L.; Sardina, Jose L.; Grebien, Florian; Di Stefano, Bruno 分享 收藏
Backtracking NOM1::ETV6 fusion to neonatal pathogenesis of t(7;12) (q36;p13) infant AML Bousquets-Munoz, Pablo; Molina, Oscar; Varela, Ignacio; Alvarez-Eguiluz, Angel; Fernandez-Mateos, Javier; Gomez, Ana; Sanchez, Elena G.; Balbin, Milagros; Ruano, David; Ramirez-Orellana, Manuel; Puente, Xose S.; Menendez, Pablo; Velasco-Hernandez, Talia 分享 收藏
Integrative single-cell expression and functional studies unravels a sensitization to cytarabine-based chemotherapy through HIF pathway inhibition in AML leukemia stem cells Velasco-Hernandez, Talia; Trincado, Juan L.; Vinyoles, Meritxell; Closa, Adria; Martinez-Moreno, Alba; Gutierrez-Aguera, Francisco; Molina, Oscar; Rodriguez-Cortez, Virginia C.; Ximeno-Parpal, Pau; Fernandez-Fuentes, Narcis; Petazzi, Paolo; Beneyto-Calabuig, Sergi; Velten, Lars; Romecin, Paola; Casquero, Raquel; Abollo-Jimenez, Fernando; de la Guardia, Rafael D.; Lorden, Patricia; Bataller, Alex; Lapillonne, Helene; Stam, Ronald W.; Vives, Susana; Torrebadell, Montserrat; Fuster, Jose L.; Bueno, Clara; Sarry, Jean-Emmanuel; Eyras, Eduardo; Heyn, Holger; Menendez, Pablo 分享 收藏
Engineered T cells secreting anti-BCMA T cell engagers control multiple myeloma and promote immune memory in vivo 分泌抗BCMA T细胞衔接剂的工程化T细胞控制多发性骨髓瘤并促进体内免疫记忆 Diez-Alonso, Laura; Falgas, Aida; Arroyo-Rodenas, Javier; Romencin, Paola A.; Martinez, Alba; Gomez-Rosel, Marina; Blanco, Belen; Jimenez-Reinoso, Anais; Mayado, Andrea; Perez-Pons, Alba; Aguilar-Sopena, Oscar; Ramirez-Fernandez, Angel; Segura-Tudela, Alejandro; Perez-Amill, Lorena; Tapia-Galisteo, Antonio; Dominguez-Alonso, Carmen; Rubio-Perez, Laura; Jara, Maria; Sole, Francesc; Hangiu, Oana; Almagro, Laura; Albitre, Angela; Penela, Petronila; Sanz, Laura; Anguita, Eduardo; Valeri, Antonio; Garcia-Ortiz, Almudena; Rio, Paula; Juan, Manel; Martinez-Lopez, Joaquin; Roda-Navarro, Pedro; Martin-Antonio, Beatriz; Orfao, Alberto; Menendez, Pablo; Bueno, Clara; alvarez-Vallina, Luis 分享 收藏
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Chromosomal instability in aneuploid acute lymphoblastic leukemia associates with disease progression 非整倍体急性淋巴细胞白血病的染色体不稳定性与疾病进展有关 Molina, Oscar; Ortega-Sabater, Carmen; Thampi, Namitha; Fernandez-Fuentes, Narcis; Guerrero-Murillo, Mercedes; Martinez-Moreno, Alba; Vinyoles, Meritxell; Velasco-Hernandez, Talia; Bueno, Clara; Trincado, Juan L.; Granada, Isabel; Campos, Diana; Gimenez, Carles; Boer, Judith M.; den Boer, Monique L.; Calvo, Gabriel F.; Camos, Mireia; Fuster, Jose-Luis; Velasco, Pablo; Ballerini, Paola; Locatelli, Franco; Mullighan, Charles G.; Spierings, Diana C. J.; Foijer, Floris; Perez-Garcia, Victor M.; Menendez, Pablo 分享 收藏
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