Kristin A. Eckert - Publications, H-index & Citations

Kristin A. Eckert

Pennsylvania State University

39H指数

99论文数

4.4K被引数

收录论文 42

发表时间

Replicative DNA polymerase epsilon and delta holoenzymes show wide-ranging inhibition at G-quadruplexes in the human genome 复制型DNA聚合酶ε和δ全酶在人类基因组中的G-四链体结构处表现出广泛的抑制。

NUCLEIC ACIDS RESEARCH

IF13.1

2025-04-29

OAAI

Hile, Suzanne E.; Weissensteiner, Matthias H.; Pytko, Kara G.; Dahl, Joseph; Kejnovsky, Eduard; Kejnovska, Iva; Hedglin, Mark; Georgakopoulos-Soares, Ilias; Makova, Kateryna D.; Eckert, Kristin A.

DNA polymerase zeta can efficiently replicate structures formed by AT/TA repeat sequences and prevent their deletion DNA聚合酶zeta可以有效复制由AT/TA重复序列形成的结构并防止其缺失

NUCLEIC ACIDS RESEARCH

IF13.1

2024-12-27

OAAI

Das, Mili; Hile, Suzanne E.; Brewster, Jennifer; Boer, Jan Leendert; Bezalel-Buch, Rachel; Guo, Qiong; Yang, Wei; Burgers, Peter M.; Eckert, Kristin A.; Freudenreich, Catherine H.

Accurate sequencing of DNA motifs able to form alternative (non-B) structures

GENOME RESEARCH

IF5.5

2023-07-11

OAAI

Weissensteiner, Matthias H.; Cremona, Marzia A.; Guiblet, Wilfried M.; Stoler, Nicholas; Harris, Robert S.; Cechova, Monika; Eckert, Kristin A.; Chiaromonte, Francesca; Huang, Yi-Fei; Makova, Kateryna D.

Variation in G-quadruplex sequence and topology differentially impacts human DNA polymerase fidelity

DNA REPAIR

IF2.7

2022-11-01

OAAI

Stein, MaryElizabeth; Hile, Suzanne E.; Weissensteiner, Matthias H.; Lee, Marietta; Zhang, Sufang; Kejnovsky, Eduard; Kejnovska, Iva; Makova, Kateryna D.; Eckert, Kristin A.

Selection and thermostability suggest G-quadruplexes are novel functional elements of the human genome

GENOME RESEARCH

IF5.5

2021-06-29

OAAI

Guiblet, Wilfried M.; DeGiorgio, Michael; Cheng, Xiaoheng; Chiaromonte, Francesca; Eckert, Kristin A.; Huang, Yi-Fei; Makova, Kateryna D.

Non-B DNA: a major contributor to small- and large-scale variation in nucleotide substitution frequencies across the genome

NUCLEIC ACIDS RESEARCH

IF13.1

2021-01-15

OAAI

Guiblet, Wilfried M.; Cremona, Marzia A.; Harris, Robert S.; Chen, Di; Eckert, Kristin A.; Chiaromonte, Francesca; Huang, Yi-Fei; Makova, Kateryna D.

Sequence and Nuclease Requirements for Breakage and Healing of a Structure-Forming (AT)n Sequence within Fragile Site FRA16D

CELL REPORTS

IF6.9

2019-04-01

OAAI

Kaushal, Simran; Wollmuth, Charles E.; Das, Kohal; Hile, Suzanne E.; Regan, Samantha B.; Barnes, Ryan P.; Haouzi, Alice; Lee, Soo Mi; House, Nealia C. M.; Guyumdzhyan, Michael; Eckert, Kristin A.; Freudenreich, Catherine H.

DNA Polymerase Eta Prevents Tumor Cell-Cycle Arrest and Cell Death during Recovery from Replication Stress

CANCER RESEARCH

IF16.6

2018-12-03

OAAI

Barnes, Ryan P.; Tsao, Wei-Chung; Moldovan, George-Lucian; Eckert, Kristin A.

Long-read sequencing technology indicates genome-wide effects of non-B DNA on polymerization speed and error rate

GENOME RESEARCH

IF5.5

2018-11-06

OAAI

Guiblet, Wilfried M.; Cremona, Marzia A.; Cechova, Monika; Harris, Robert S.; Kejnovska, Iva; Kejnovsky, Eduard; Eckert, Kristin; Chiaromonte, Francesca; Makova, Kateryna D.

Genome-wide Identification of Structure-Forming Repeats as Principal Sites of Fork Collapse upon ATR Inhibition

MOLECULAR CELL

IF16.6

2018-10-01

OAAI

Shastri, Nishita; Tsai, Yu-Chen; Hile, Suzanne; Jordan, Deondre; Powell, Barrett; Chen, Jessica; Maloney, Dillon; Dose, Marei; Lo, Yancy; Anastassiadis, Theonie; Rivera, Osvaldo; Kim, Taehyong; Shah, Sharvin; Borole, Piyush; Asija, Kanika; Wang, Xiang; Smith, Kevin D.; Finn, Darren; Schug, Jonathan; Casellas, Rafael; Yatsunyk, Liliya A.; Eckert, Kristin A.; Brown, Eric J.

DNA polymerases eta and kappa exchange with the polymerase delta holoenzyme to complete common fragile site synthesis

DNA REPAIR

IF2.7

2017-09-01

OAAI

Barnes, Ryan P.; Hile, Suzanne E.; Lee, Marietta Y.; Eckert, Kristin A.

A genome-wide analysis of common fragile sites: What features determine chromosomal instability in the human genome? (vol 22, pg 993, 2012)

GENOME RESEARCH

IF5.5

2016-10-03

OAAI

Fungtammasan, Arkarachai; Walsh, Erin; Chiaromonte, Francesca; Eckert, Kristin A.; Makova, Kateryna D.

Reverse Transcription Errors and RNA-DNA Differences at Short Tandem Repeats

MOLECULAR BIOLOGY AND EVOLUTION

IF5.3

2016-07-12

OAAI

Fungtammasan, Arkarachai; Tomaszkiewicz, Marta; Campos-Sanchez, Rebeca; Eckert, Kristin A.; DeGiorgio, Michael; Makova, Kateryna D.

Genetic evidence that both dNTP-stabilized and strand slippage mechanisms may dictate DNA polymerase errors within mononucleotide microsatellites

DNA REPAIR

IF2.7

2015-05-01

OAAI

Baptiste, Beverly A.; Jacob, Kimberly D.; Eckert, Kristin A.

Accurate typing of short tandem repeats from genome-wide sequencing data and its applications

GENOME RESEARCH

IF5.5

2015-03-30

OAAI

Fungtammasan, Arkarachai; Ananda, Guruprasad; Hile, Suzanne E.; Su, Marcia Shu-Wei; Sun, Chen; Harris, Robert; Medvedev, Paul; Eckert, Kristin; Makova, Kateryna D.

Human PrimPol is a highly error-prone polymerase regulated by single-stranded DNA binding proteins

NUCLEIC ACIDS RESEARCH

IF13.1

2014-12-29

OAAI

Guilliam, Thomas A.; Jozwiakowski, Stanislaw K.; Ehlinger, Aaron; Barnes, Ryan P.; Rudd, Sean G.; Bailey, Laura J.; Skehel, J. Mark; Eckert, Kristin A.; Chazin, Walter J.; Doherty, Aidan J.

Microsatellite Interruptions Stabilize Primate Genomes and Exist as Population-Specific Single Nucleotide Polymorphisms within Individual Human Genomes

PLOS GENETICS

IF3.7

2014-07-17

OAAI

Ananda, Guruprasad; Hile, Suzanne E.; Breski, Amanda; Wang, Yanli; Kelkar, Yogeshwar; Makova, Kateryna D.; Eckert, Kristin A.

Interplay between DNA repair and inflammation, and the link to cancer DNA修复和炎症之间的相互作用，以及与癌症的联系

CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

IF6.4

2014-01-13

155

OAAI

Kidane, Dawit; Chae, Wook Jin; Czochor, Jennifer; Eckert, Kristin A.; Glazer, Peter M.; Bothwell, Alfred L. M.; Sweasy, Joann B.

DNA synthesis by Pol η promotes fragile site stability by preventing under-replicated DNA in mitosis

JOURNAL OF CELL BIOLOGY

IF6.4

2013-04-22

171

OAAI

Bergoglio, Valerie; Boyer, Anne-Sophie; Walsh, Erin; Naim, Valeria; Legube, Gaelle; Lee, Marietta Y. W. T.; Rey, Laurie; Rosselli, Filippo; Cazaux, Christophe; Eckert, Kristin A.; Hoffmann, Jean-Sebastien

Distinct Mutational Behaviors Differentiate Short Tandem Repeats from Microsatellites in the Human Genome

GENOME BIOLOGY AND EVOLUTION

IF2.8

2012-12-13

OAAI

Ananda, Guruprasad; Walsh, Erin; Jacob, Kimberly D.; Krasilnikova, Maria; Eckert, Kristin A.; Chiaromonte, Francesca; Makova, Kateryna D.

研究方向