Philippe Kastner - Publications, H-index & Citations

Philippe Kastner

institut national de la sante et de la recherche medicale (inserm)

67H指数

125论文数

2.6W被引数

收录论文 33

发表时间

Ikaros is a principal regulator of Aire+ mTEC homeostasis, thymic mimetic cell diversity, and central tolerance

SCIENCE IMMUNOLOGY

IF16.3

2023-10-27

PREAI

Sin, Jun Hyung; Sucharov, Juliana; Kashyap, Sujit; Wang, Yi; Proekt, Irina; Liu, Xian; Parent, Audrey, V; Gupta, Alexander; Kastner, Philippe; Chan, Susan; Gardner, James M.; Ntranos, Vasilis; Miller, Corey N.; Anderson, Mark S.; Schjerven, Hilde; Waterfield, Michael R.

Ikaros Represses the Transcriptional Response to Notch Signaling in T-Cell Development

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

OAAI

Kleinmann, Eva; Le Lay, Anne-Solen Geimer; Sellars, MacLean; Kastner, Philippe; Chan, Susan

Notch activation is an early and critical event during T-cell leukemogenesis in Ikaros-deficient mice

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

156

OAAI

Dumortier, A; Jeannet, R; Kirstetter, P; Kleinmann, E; Sellars, M; dos Santos, NR; Thibault, C; Barths, J; Ghysdael, J; Punt, JA; Kastner, P; Chan, S

Ikaros deficiency is associated with aggressive BCR-ABL1 B-cell precursor acute lymphoblastic leukemia independent of the lineage and developmental origin

HAEMATOLOGICA

IF7.9

2021-09-30

OAAI

Simand, Celestine; Keime, Celine; Caye, Aurelie; Arfeuille, Chloe; Passet, Marie; Kim, Rathana; Cave, Helene; Clappier, Emmanuelle; Kastner, Philippe; Chan, Susan; Heizmann, Beate

Helios represses megakaryocyte priming in hematopoietic stem and progenitor cells

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2021-08-30

OAAI

Cova, Giovanni; Taroni, Chiara; Deau, Marie-Celin; Cai, Qi; Mittelheisser, Vincent; Philipps, Muriel; Jung, Matthieu; Cerciat, Marie; Le Gras, Stephanie; Thibault-Carpentier, Christelle; Jost, Bernard; Carlsson, Leif; Thornton, M. Angela; Shevach, M. Ethan; Kirstetter, Peggy; Kastner, Philippe; Chan, Susan

CD4+ T cells require Ikaros to inhibit their differentiation toward a pathogenic cell fate

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2021-04-23

OAAI

Bernardi, Chiara; Maurer, Gaetan; Ye, Tao; Marchal, Patricia; Jost, Bernard; Wissler, Manuela; Maurer, Ulrich; Kastner, Philippe; Chan, Susan; Charvet, Celine

The Ikaros family in lymphocyte development

CURRENT OPINION IN IMMUNOLOGY

IF5.8

2018-04-01

PREAI

Heizmann, Beate; Kastner, Philippe; Chan, Susan

Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons

DEVELOPMENT

IF3.6

2017-04-15

OAAI

Martin-Ibanez, Raquel; Pardo, Monica; Giralt, Albert; Miguez, Andres; Guardia, Ines; Marion-Poll, Lucile; Herranz, Cristina; Esgleas, Miriam; Garcia-Diaz Barriga, Gerardo; Edel, Michael J.; Vicario-Abejon, Carlos; Alberch, Jordi; Girault, Jean-Antoine; Chan, Susan; Kastner, Philippe; Canals, Josep M.

Ikaros Inhibits Group 3 Innate Lymphoid Cell Development and Function by Suppressing the Aryl Hydrocarbon Receptor Pathway

IMMUNITY

IF26.3

2016-07-01

OAAI

Li, Shiyang; Heller, Jennifer J.; Bostick, John W.; Lee, Aileen; Schjerven, Hilde; Kastner, Philippe; Chan, Susan; Chen, Zongming E.; Zhou, Liang

Ikaros Is a Negative Regulator of B1 Cell Development and Function

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2016-04-01

OAAI

Macias-Garcia, Alejandra; Heizmann, Beate; Sellars, MacLean; Marchal, Patricia; Dali, Hayet; Pasquali, Jean-Louis; Muller, Sylviane; Kastner, Philippe; Chan, Susan

Ikaros mediates gene silencing in T cells through Polycomb repressive complex 2

NATURE COMMUNICATIONS

IF15.7

2015-11-09

OAAI

Oravecz, Attila; Apostolov, Apostol; Polak, Katarzyna; Jost, Bernard; Le Gras, Stephanie; Chan, Susan; Kastner, Philippe

IKZF1 deletion is an independent prognostic marker in childhood B-cell precursor acute lymphoblastic leukemia, and distinguishes patients benefiting from pulses during maintenance therapy: results of the EORTC Children's Leukemia Group study 58951

LEUKEMIA

IF13.4

2015-06-08

PREAI

Clappier, E.; Grardel, N.; Bakkus, M.; Rapion, J.; De Moerloose, B.; Kastner, P.; Caye, A.; Vivent, J.; Costa, V.; Ferster, A.; Lutz, P.; Mazingue, F.; Millot, F.; Plantaz, D.; Plat, G.; Plouvier, E.; Poiree, M.; Sirvent, N.; Uyttebroeck, A.; Yakouben, K.; Girard, S.; Dastugue, N.; Suciu, S.; Benoit, Y.; Bertrand, Y.; Cave, H.

The Tumor Suppressor Ikaros Shapes the Repertoire of Notch Target Genes in T Cells

SCIENCE SIGNALING

IF6.6

2014-03-18

PREAI

Geimer Le Lay, Anne-Solen; Oravecz, Attila; Mastio, Jerome; Jung, Claudia; Marchal, Patricia; Ebel, Claudine; Dembele, Doulaye; Jost, Bernard; Le Gras, Stephanie; Thibault, Christelle; Borggrefe, Tilman; Kastner, Philippe; Chan, Susan

Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signals

JOURNAL OF EXPERIMENTAL MEDICINE

IF10.6

2013-12-02

OAAI

Heizmann, Beate; Kastner, Philippe; Chan, Susan

A multiply redundant genetic switch 'locks in' the transcriptional signature of regulatory T cells

NATURE IMMUNOLOGY

IF27.6

2012-09-09

253

OAAI

Fu, Wenxian; Ergun, Ayla; Lu, Ting; Hill, Jonathan A.; Haxhinasto, Sokol; Fassett, Marlys S.; Gazit, Roi; Adoro, Stanley; Glimcher, Laurie; Chan, Susan; Kastner, Philippe; Rossi, Derrick; Collins, James J.; Mathis, Diane; Benoist, Christophe

Biclonal and biallelic deletions occur in 20% of B-ALL cases with IKZF1 mutations

LEUKEMIA

IF13.4

2012-07-18

PREAI

Dupuis, A.; Gaub, M. P.; Legrain, M.; Drenou, B.; Mauvieux, L.; Lutz, P.; Herbrecht, R.; Chan, S.; Kastner, P.

Haploinsufficiency of the IKZF1 (IKAROS) tumor suppressor gene cooperates with BCR-ABL in a transgenic model of acute lymphoblastic leukemia

LEUKEMIA

IF13.4

2010-04-15

PREAI

Virely, C.; Moulin, S.; Cobaleda, C.; Lasgi, C.; Alberdi, A.; Soulier, J.; Sigaux, F.; Chan, S.; Kastner, P.; Ghysdael, J.