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J

James J. Collins

broad institute
H指数:162
被引数:11.2万

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Deep learning–enabled discovery of antibiotics effective against Neisseria gonorrhoeae

深度学习赋能的针对淋病奈瑟菌的抗生素发现

Science Translational Medicine
IF14.6
2026-06-170
PRE
Melis N. Anahtar; Jacqueline A. Valeri; Seyed Majed Modaresi; Aarti Krishnan; Nina M. Donghia; Samantha G. Palace; Erica J. Zheng; Aakanksha Gulati; Alicia Jorgenson; Abidemi Junaid; Parijat Bandyopadhyay; Andreas Luttens; Krishna Suresh; Paige Edwards; Felix Wong; Yu Zhang; Danilo Ritz; Margaux Gaborieau; Edmund Loh; Massimiliano Gaetani; Marie-Stephanie Aschtgen; Amir Ata Saei; Yonatan H. Grad; Donald E. Ingber; James J. Collins
Active learning framework leveraging transcriptomics identifies modulators of disease phenotypes

利用转录组学进行主动学习框架识别疾病表型调节因子

Science
IF45.8
2025-10-230
PRE
Benjamin DeMeo; Charlotte Nesbitt; Samuel A. Miller; Daniel B. Burkhardt; Inna Lipchina; Doris Fu; Peter Holderrieth; David Kim; Sergey Kolchenko; Artur Szalata; Ishan Gupta; Christine Kerr; Thomas Pfefer; Raziel Rojas-Rodriguez; Sunil Kuppassani; Laurens Kruidenier; Parul B. Doshi; Mahdi Zamanighomi; James J. Collins; Alex K. Shalek; Fabian J. Theis; Mauricio Cortes
Optogenetics-enabled discovery of integrated stress response modulators

光遗传学赋能的整合应激反应调节剂的发现

Cell
IF42.5
2025-07-110
PRE
Felix Wong; Alicia Li; Satotaka Omori; Ryan S. Lach; Jose Nunez; Yunke Ren; Sean P. Brown; Vipul Singhal; Brent R. Lyda; Taivan Batjargal; Ethan Dickson; Jose Roberto Rodrigues Reyes; Juan Manual Uruena Vargas; Shalaka Wahane; Hahn Kim; James J. Collins; Maxwell Z. Wilson
Rapid discovery and evolution of nanosensors containing fluorogenic amino acids

含有荧光氨基酸的纳米传感器的快速发现和进化

NATURE COMMUNICATIONS
IF15.7
2024-09-050
OAAI
Kuru, Erkin; Rittichier, Jonathan; de Puig, Helena; Flores, Allison; Rout, Subhrajit; Han, Isaac; Reese, Abigail E.; Bartlett, Thomas M.; De Moliner, Fabio; Bernier, Sylvie G.; Galpin, Jason D.; Marchand, Jorge; Bedell, William; Robinson-McCarthy, Lindsey; Ahern, Christopher A.; Bernhardt, Thomas G.; Rudner, David Z.; Collins, James J.; Vendrell, Marc; Church, George M.
Rapid, multiplexed, and enzyme-free nucleic acid detection using programmable aptamer-based RNA switches

使用可编程的基于适体的RNA开关进行快速，多路和无酶的核酸检测

CHEM
IF19.6
2024-07-012
PRE
Yan, Zhaoqing; Eshed, Amit; Tang, Anli A.; Arevalos, Nery R.; Ticktin, Zachary M.; Chaudhary, Soma; Ma, Duo; Mccutcheon, Griffin; Li, Yudan; Wu, Kaiyue; Saha, Sanchari; Alcantar-Fernandez, Jonathan; Moreno-Camacho, Jose L.; Campos-Romero, Abraham; Collins, James J.; Yin, Peng; Green, Alexander A.
Discovery of a structural class of antibiotics with explainable deep learning

通过可解释的深度学习发现抗生素的结构类

Nature
IF48.5
2023-12-200
PRE
Felix Wong; Erica J. Zheng; Jacqueline A. Valeri; Nina M. Donghia; Melis N. Anahtar; Satotaka Omori; Alicia Li; Andres Cubillos-Ruiz; Aarti Krishnan; Wengong Jin; Abigail L. Manson; Jens Friedrichs; Ralf Helbig; Behnoush Hajian; Dawid K. Fiejtek; Florence F. Wagner; Holly H. Soutter; Ashlee M. Earl; Jonathan M. Stokes; Lars D. Renner; James J. Collins

研究方向

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H
Hu Li
H 指数:62论文数:526被引数:1.9万
G
George Q. Daley
H 指数:128论文数:641被引数:7.8万
F
Felix Wong
H 指数:26论文数:48被引数:2,808
P
Peter Q. Nguyen
H 指数:28论文数:53被引数:5,544
Y
Yuin‐Han Loh
H 指数:41论文数:114被引数:1.8万
M
Michael A. Kohanski
H 指数:31论文数:192被引数:1.1万
D
Daniel J. Dwyer
H 指数:19论文数:35被引数:1.0万
A
Ahmad S. Khalil
H 指数:41论文数:157被引数:8,748
N
Nina M. Donghia
H 指数:20论文数:34被引数:1.0万
G
Graham C. Walker
H 指数:101论文数:642被引数:4.4万