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Bevacizumab-based chemotherapy adaptive to pharmacokinetic of bevacizumab in first-line treatment of patients with unresectable metastatic colorectal cancer: A double-blind, multicenter, randomized phase III trial study (PHARBEVACOL trial) 基于贝伐珠单抗的化疗,根据贝伐珠单抗药代动力学适应性调整,用于不可切除性转移性结直肠癌患者的一线治疗:一项双盲、多中心、随机III期临床试验研究(PHARBEVACOL试验) Lecomtea, Thierry; Giraudeauc, Bruno; Phelipd, Jean-Marc; Tournigande, Christophe; Ducreuxf, Michel; Tougerong, David; Lepageh, Come; Mineuri, Laurent; Laplaigej, Philippe; Desgrippesk, Romain; Artrul, Pascal; Borgm, Christophe; Jaryn, Marine; Boucheo, Olivier; Metges, Jean-Philippe; Guimbaud, Rosine; Aparicio, Thomas; Foubert, Fanny; Hautefeuillet, Vincent; Muller, Marie; Bouhier-Leporrierv, Karine; Darriusw, Remi; Lobetb, Sarah; Monmousseaux, Fanny; Bejan-Angoulvanty, Theodora; Paintaud, Gilles; Ternant, David 分享 收藏
A Fab of trastuzumab to treat HER2 overexpressing breast cancer brain metastases 曲妥珠单抗治疗HER2过表达乳腺癌脑转移的Fab Angeli, Eurydice; Paris, Justine; Le Tilly, Olivier; Desvignes, Celine; Gapihan, Guillaume; Boquet, Didier; Pamoukdjian, Frederic; Hamdan, Diaddin; Rigal, Marthe; Poirier, Florence; Lutomski, Didier; Azibani, Feriel; Mebazaa, Alexandre; Herbet, Amaury; Mabondzo, Aloise; Falgarone, Geraldine; Janin, Anne; Paintaud, Gilles; Bousquet, Guilhem 分享 收藏
Eculizumab dose tapering should take into account the nonlinearity of its pharmacokinetics Tilly, Olivier Le; Gatault, Philippe; Semlali, Saida; Sberro-Soussan, Rebecca; Passot, Christophe; Bertrand, Dominique; Desvignes, Celine; Caillard, Sophie; Paintaud, Gilles; Halimi, Jean-Michel; Ternant, David 分享 收藏
Confounding mitigation for the exposure-response relationship of bevacizumab in colorectal cancer patients 结直肠癌患者贝伐单抗暴露-反应关系的混杂缓解 Lobet, Sarah; Caulet, Morgane; Paintaud, Gilles; Azzopardi, Nicolas; Desvignes, Celine; Chautard, Romain; Borg, Christophe; Capitain, Olivier; Ferru, Aurelie; Bouche, Olivier; Lecomte, Thierry; Ternant, David 分享 收藏
Efficacy and safety of intravenous bevacizumab on severe bleeding associated with hemorrhagic hereditary telangiectasia: A national, randomized multicenter trial Dupuis-Girod, Sophie; Riviere, Sophie; Lavigne, Christian; Fargeton, Anne-Emmanuelle; Gilbert-Dussardier, Brigitte; Grobost, Vincent; Leguy-Seguin, Vanessa; Maillard, Helene; Mohamed, Shirine; Decullier, Evelyne; Roux, Adeline; Bernard, Lorraine; Saurin, Jean-Christophe; Saroul, Nicolas; Faure, Frederic; Cartier, Cesar; Altwegg, Romain; Laccourreye, Laurent; Oberti, Frederic; Beaudoin, Marjolaine; Dhelens, Carole; Desvignes, Celine; Azzopardi, Nicolas; Paintaud, Gilles; Hermann, Ruben; Chinet, Thierry 分享 收藏
Low to undetectable Omicron BQ.1.1 neutralization by patient's sera a month after initiation of AZD7442 600 mg Touret, Franck; Martin-Blondel, Guillaume; de Lamballerie, Xavier; Dupont, Axelle; Izopet, Jacques; Mentre, France; Kamar, Nassim; Autran, Brigitte; Paintaud, Gilles; Caillard, Sophie; Richez, Christophe; Couzi, Lionel; Xhaard, Alienor; Marjanovic, Zora; Avouac, Jerome; Jacquet, Caroline; Anglicheau, Dany; Cheminant, Morgane; Yazdanpanah, Yazdan; N'Guyen, Stephanie; Terrier, Benjamin; Gottenberg, Jacques Eric; Besson, Caroline; Letrou, Sophie; Kali, Sabrina; Angoulvant, Denis; Barthelemy, Karine; Priet, Stephane; Nurtop, Elif; Sanchez, Ventzislava Petrov; Tardivon, Coralie; Blancho, Gilles; Le Bourgeois, Amandine; Levy, Vincent 分享 收藏
Infliximab Efficacy May Be Linked to Full TNF-α Blockade in Peripheral Compartment-A Double Central-Peripheral Target-Mediated Drug Disposition (TMDD) Model Ternant, David; Le Tilly, Olivier; Picon, Laurence; Moussata, Driffa; Passot, Christophe; Bejan-Angoulvant, Theodora; Desvignes, Celine; Mulleman, Denis; Goupille, Philippe; Paintaud, Gilles 分享 收藏
A phase II randomised study of preoperative trastuzumab alone or combined with everolimus in patients with early HER2-positive breast cancer and predictive biomarkers (RADHER trial) Campone, Mario; Bachelot, Thomas; Treilleux, Isabelle; Pistilli, Barbara; Salleron, Julia; Seegers, Valerie; Arnedos, Monica; Loussouarn, Delphine; Wang, Qing; Vanlemmens, Laurence; Jimenez, Marta; Rios, Maria; Dieras, Veronique; Leroux, Agnes; Paintaud, Gilles; Rezai, Keyvan; Andre, Fabrice; Lion, Maeva; Merlin, Jean-Louis 分享 收藏
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Cetuximab could be administered once every two weeks instead of once weekly Lobet, S.; Paintaud, G.; Azzopardi, N.; Passot, C.; Caulet, M.; Chautard, R.; Vignault-Desvignes, C.; Capitain, O.; Tougeron, D.; Boisdron-Celle, M.; Ternant, D.; Lecomte, T. 分享 收藏
Antigen Mass May Influence Trastuzumab Concentrations in Cerebrospinal Fluid After Intrathecal Administration Le Tilly, Olivier; Azzopardi, Nicolas; Bonneau, Claire; Desvignes, Celine; Oberkampf, Florence; Ezzalfani, Monia; Ternant, David; Turbiez, Isabelle; Gutierrez, Maya; Paintaud, Gilles 分享 收藏
Feasibility and safety of tailored dosing schedule for eculizumab based on therapeutic drug monitoring: Lessons from a prospective multicentric study 基于治疗药物监测的依库珠单抗定制给药方案的可行性和安全性: 一项前瞻性多中心研究的经验教训 Passot, Christophe; Sberro-Soussan, Rebecca; Bertrand, Dominique; Caillard, Sophie; Schvartz, Betoul; Domenger, Camille; Contin-Bordes, Cecile; Paintaud, Gilles; Halimi, Jean-Michel; Ternant, David; Gatault, Philippe 分享 收藏
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Skin inflammatory response and efficacy of anti-epidermal growth factor receptor therapy in metastatic colorectal cancer (CUTACETUX) Tougeron, David; Emambux, Sheik; Favot, Laure; Lecomte, Thierry; Wierzbicka-Hainaut, Ewa; Samimi, Mahtab; Frouin, Eric; Azzopardi, Nicolas; Chevrier, Jocelyn; Serres, Laura; Godet, Julie; Levillain, Pierre; Paintaud, Gilles; Ferru, Aurelie; Rouleau, Laetitia; Delwail, Adriana; Silvain, Christine; Tasu, Jean-Pierre; Morel, Franck; Ragot, Stephanie; Lecron, Jean-Claude 分享 收藏
Long-term outcomes in patients with PET-predicted poor-responsive HER2-positive breast cancer treated with neoadjuvant bevacizumab added to trastuzumab and docetaxel: 5-year follow-up of the randomised Avataxher study Coudert, Bruno; Pierga, Jean-Yves; Mouret-Reynier, Marie-Ange; Kerrou, Kaldoun; Ferrero, Jean-Marc; Petit, Thierry; Le Du, Fanny; Dupre, Pierre-Francois; Bachelot, Thomas; Gabelle, Philippe; Chauvet, Marie-Pierre; Coeffic, David; Barbe, Catherine; Prevost, Jean-Briac; Paintaud, Gilles; Thibault, Gilles; Ferhat, Abdennour; Dupin, Julien; Berriolo-Riedinger, Alina; Arnould, Laurent 分享 收藏
Kinetic modelling of myocardial necrosis biomarkers offers an easier, reliable and more acceptable assessment of infarct size Chadet, Stephanie; Ternant, David; Roubille, Francois; Bejan-Angoulvant, Theodora; Prunier, Fabrice; Mewton, Nathan; Paintaud, Gilles; Ovize, Michel; Dupuy, Anne Marie; Angoulvant, Denis; Ivanes, Fabrice 分享 收藏
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Intra-tracheal amikacin spray delivery in healthy mechanically ventilated piglets Guillon, Antoine; Darrouzain, Francois; Heuze-Voure'h, Nathalie; Petitcollin, Antoine; Barc, Celine; Vecellio, Laurent; Cormier, Benedicte; Lanotte, Philippe; Sarradin, Pierre; Dequin, Pierre-Francois; Paintaud, Gilles; Ehrmann, Stephan 分享 收藏