未登录 Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence Lluch, Aina; Latorre, Jessica; Serena-Maione, Angela; Espadas, Isabel; Caballano-Infantes, Estefania; Moreno-Navarrete, Jose M.; Oliveras-Canellas, Nuria; Ricart, Wifredo; Malagon, Maria M.; Martin-Montalvo, Alejandro; Birchmeier, Walter; Szymanski, Witold; Graumann, Johannes; Gomez-Serrano, Maria; Sommariva, Elena; Fernandez-Real, Jose M.; Ortega, Francisco J. J. 分享 收藏
Negative feedback loop of Wnt signaling through upregulation of conductin/Axin2 in colorectal and liver tumors Lustig, B; Jerchow, B; Sachs, M; Weiler, S; Pietsch, T; Karsten, U; van de Wetering, M; Clevers, H; Schlag, PM; Birchmeier, W; Behrens, J 分享 收藏
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Concomitant deletion of Ptpn6 and Ptpn11 in T cells fails to improve anticancer responses Ventura, Pedro M. O.; Gakovic, Milica; Fischer, Berenice A.; Spinelli, Laura; Rota, Giorgia; Pathak, Shalini; Khameneh, Hanif J.; Zenobi, Alessandro; Thomson, Sarah; Birchmeier, Walter; Cantrell, Doreen A.; Guarda, Greta 分享 收藏
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MLL1 is required for maintenance of intestinal stem cells Goveas, Neha; Waskow, Claudia; Arndt, Kathrin; Heuberger, Julian A.; Zhang, Qinyu; Alexopoulou, Dimitra A.; Dahl, Andreas; Birchmeier, Walter A.; Anastassiadis, Konstantinos; Stewart, A. Francis A.; Kranz, Andrea 分享 收藏
Oxidized LDL-dependent pathway as new pathogenic trigger in arrhythmogenic cardiomyopathy Sommariva, Elena; Stadiotti, Ilaria; Casella, Michela; Catto, Valentina; Dello Russo, Antonio; Carbucicchio, Corrado; Arnaboldi, Lorenzo; De Metrio, Simona; Milano, Giuseppina; Scopece, Alessandro; Casaburo, Manuel; Andreini, Daniele; Mushtaq, Saima; Conte, Edoardo; Chiesa, Mattia; Birchmeier, Walter; Cogliati, Elisa; Paolin, Adolfo; Konig, Eva; Meraviglia, Viviana; De Musso, Monica; Volani, Chiara; Cattelan, Giada; Rauhe, Werner; Turnu, Linda; Porro, Benedetta; Pedrazzini, Matteo; Camera, Marina; Corsini, Alberto; Tondo, Claudio; Rossini, Alessandra; Pompilio, Giulio 分享 收藏
High Yap and Mll1 promote a persistent regenerative cell state induced by Notch signaling and loss of p53 Heuberger, Julian; Grinat, Johanna; Kosel, Frauke; Liu, Lichao; Kunz, Severine; Vidal, Ramon Oliveira; Keil, Marlen; Haybaeck, Johannes; Robine, Sylvie; Louvard, Daniel; Regenbrecht, Christian; Sporbert, Anje; Sauer, Sascha; von Eyss, Bjorn; Sigal, Michael; Birchmeier, Walter 分享 收藏
YAP and β-Catenin Cooperate to Drive Oncogenesis in Basal Breast Cancer Quinn, Hazel M.; Vogel, Regina; Popp, Oliver; Mertins, Philipp; Lan, Linxiang; Messerschmidt, Clemens; Landshammer, Alexandro; Lisek, Kamil; Chateau-Joubert, Sophie; Marangoni, Elisabetta; Koren, Elle; Fuchs, Yaron; Birchmeier, Walter 分享 收藏
The epigenetic regulator Mll1 is required for Wnt-driven intestinal tumorigenesis and cancer stemness Grinat, Johanna; Heuberger, Julian; Vidal, Ramon Oliveira; Goveas, Neha; Kosel, Frauke; Berenguer-Llergo, Antoni; Kranz, Andrea; Wulf-Goldenberg, Annika; Behrens, Diana; Melcher, Balint; Sauer, Sascha; Vieth, Michael; Batlle, Eduard; Stewart, A. Francis; Birchmeier, Walter 分享 收藏
From Pyrazolones to Azaindoles: Evolution of Active-Site SHP2 Inhibitors Based on Scaffold Hopping and Bioisosteric Replacement Mostinski, Yelena; Heynen, Guus J. J. E.; Lopez-Alberca, Maria Pascual; Paul, Jerome; Miksche, Sandra; Radetzki, Silke; Schaller, David; Shanina, Elena; Seyffarth, Carola; Kolomeets, Yuliya; Ziebart, Nandor; de Schryver, Judith; Oestreich, Sylvia; Neuenschwander, Martin; Roske, Yvette; Heinemann, Udo; Rademacher, Christoph; Volkamer, Andrea; von Kries, Jens Peter; Birchmeier, Walter; Nazare, Marc 分享 收藏
Tracing tumorigenesis in a solid tumor model at single-cell resolution Praktiknjo, Samantha D.; Obermayer, Benedikt; Zhu, Qionghua; Fang, Liang; Liu, Haiyue; Quinn, Hazel; Stoeckius, Marlon; Kocks, Christine; Birchmeier, Walter; Rajewsky, Nikolaus 分享 收藏
Inhibiting WNT and NOTCH in renal cancer stem cells and the implications for human patients Fendler, Annika; Bauer, Daniel; Busch, Jonas; Jung, Klaus; Wulf-Goldenberg, Annika; Kunz, Severine; Song, Kun; Myszczyszyn, Adam; Elezkurtaj, Sefer; Erguen, Bettina; Jung, Simone; Chen, Wei; Birchmeier, Walter 分享 收藏
Decreased microglial Wnt/β-catenin signalling drives microglial pro-inflammatory activation in the developing brain 小胶质细胞Wnt/β-catenin信号传导降低驱动发育中的大脑中小胶质细胞促炎激活 Van Steenwinckel, Juliette; Schang, Anne-Laure; Krishnan, Michelle L.; Degos, Vincent; Delahaye-Duriez, Andree; Bokobza, Cindy; Csaba, Zsolt; Verdonk, Franck; Montane, Amelie; Sigaut, Stephanie; Hennebert, Olivier; Lebon, Sophie; Schwendimann, Leslie; Le Charpentier, Tifenn; Hassan-Abdi, Rahma; Ball, Gareth; Aljabar, Paul; Saxena, Alka; Holloway, Rebecca K.; Birchmeier, Walter; Baud, Olivier; Rowitch, David; Miron, Veronique; Chretien, Fabrice; Leconte, Claire; Besson, Valerie C.; Petretto, Enrico G.; Edwards, A. David; Hagberg, Henrik; Soussi-Yanicostas, Nadia; Fleiss, Bobbi; Gressens, Pierre 分享 收藏
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Spatially Restricted Stromal Wnt Signaling Restrains Prostate Epithelial Progenitor Growth through Direct and Indirect Mechanisms Wei, Xing; Zhang, Li; Zhou, Zhicheng; Kwon, Oh-Joon; Zhang, Yiqun; Hoang Nguyen; Dumpit, Ruth; True, Lawrence; Nelson, Peter; Dong, Baijun; Xue, Wei; Birchmeier, Walter; Taketo, Makoto M.; Xu, Feng; Creighton, Chad J.; Ittmann, Michael M.; Xin, Li 分享 收藏
Shp-2 is critical for ERK and metabolic engagement downstream of IL-15 receptor in NK cells Shp-2对NK细胞中ERK和IL-15受体下游的代谢参与至关重要 Niogret, Charlene; Miah, S. M. Shahjahan; Rota, Giorgia; Fonta, Nicolas P.; Wang, Haiping; Held, Werner; Birchmeier, Walter; Sexl, Veronica; Yang, Wentian; Vivier, Eric; Ho, Ping-Chih; Brossay, Laurent; Guarda, Greta 分享 收藏
The Wnt-Driven Mll1 Epigenome Regulates Salivary Gland and Head and Neck Cancer Zhu, Qionghua; Fang, Liang; Heuberger, Julian; Kranz, Andrea; Schipper, Joerg; Scheckenbach, Kathrin; Vidal, Ramon Oliveira; Sunaga-Franze, Daniele Yumi; Mueller, Marion; Wulf-Goldenberg, Annika; Sauer, Sascha; Birchmeier, Walter 分享 收藏
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