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Comparability of Gastrointestinal Microbiome and Bile Acid Profiles in Patients With First or Multiply Recurrent Clostridioides difficile Infection 首次或多次复发性*Clostridioides difficile*感染患者胃肠道微生物组与胆汁酸谱的可比性 Bryant, Jessica A.; Straub, Timothy J.; Pardi, Darrell S.; Litcofsky, Kevin D.; Kelly, Colleen R.; Chafee, Meghan E.; Cohen, Stuart H.; Khanna, Sahil; Berenson, Charles S.; Wortman, Jennifer; Sims, Matthew; Ford, Christopher B.; Lombardo, Mary-Jane; Mcgovern, Barbara H.; von Moltke, Lisa; Kraft, Colleen S.; Henn, Matthew R.; Hasson, Brooke R. 分享 收藏
Randomized placebo-controlled, biomarker-stratified phase 1b microbiome modulation trial for metastatic melanoma demonstrates impact of antibiotic pre-conditioning regimen on the microbiome and immunity Oliva, Isabella C. Glitza; Seo, Yongwoo David; Spencer, Christine N.; Wortman, Jennifer R.; Burton, Elizabeth M.; Alayli, Farah A.; Loo, Christopher; Gautam, Shikha; Damania, Ashish V.; Densmore, Julie; Fairchild, Justin; Cabanski, Christopher; Wong, Matthew C.; Peterson, Christine B.; Weiner, Brian; Hicks, Nathan; Aunins, John; McChalicher, Christopher; Tetzlaff, Michael T.; Hamid, Omid; Ott, Patrick A.; Boland, Genevieve M.; Sullivan, Ryan J.; Grossmann, Kenneth F.; Ajami, Nadim J.; LaVallee, Theresa M.; Henn, Matthew R.; Tawbi, Hussein A.; Wargo, Jennifer A. 分享 收藏
Randomized Placebo-Controlled, Biomarker-Stratified Phase Ib Microbiome Modulation in Melanoma: Impact of Antibiotic Preconditioning on Microbiome and Immunity 黑色素瘤中随机安慰剂对照、生物标志物分层Ib期微生物组调节: 抗生素预处理对微生物组和免疫的影响 Glitza, Isabella C.; Seo, Yongwoo David; Spencer, Christine N.; Wortman, Jennifer R.; Burton, Elizabeth M.; Alayli, Farah A.; Loo, Christopher P.; Gautam, Shikha; Damania, Ashish; Densmore, Julie; Fairchild, Justin; Cabanski, Christopher R.; Wong, Matthew C.; Peterson, Christine B.; Weiner, Brian; Hicks, Nathan; Aunins, John; McChalicher, Christopher; Walsh, Emily; Tetzlaff, Michael T.; Hamid, Omid; Ott, Patrick A.; Boland, Genevieve M.; Sullivan, Ryan J.; Grossmann, Kenneth F.; Ajami, Nadim J.; LaVallee, Theresa; Henn, Matthew R.; Tawbi, Hussein A.; Wargo, Jennifer A. 分享 收藏
Impact of a Purified Microbiome Therapeutic on Abundance of Antimicrobial Resistance Genes in Patients With Recurrent Clostridioides difficile Infection Straub, Timothy J.; Lombardo, Mary-Jane; Bryant, Jessica A.; Diao, Liyang; Lodise, Thomas P.; Freedberg, Daniel E.; Wortman, Jennifer R.; Litcofsky, Kevin D.; Hasson, Brooke R.; Mcgovern, Barbara H.; Ford, Christopher B.; Henn, Matthew R. 分享 收藏
A Phase 1b Safety Study of SER-287, a Spore-Based Microbiome Therapeutic, for Active Mild to Moderate Ulcerative Colitis 基于孢子的微生物组疗法SER-287治疗活动性轻度至中度溃疡性结肠炎的1b期安全性研究 Henn, Matthew R.; O'Brien, Edward J.; Diao, Liyang; Feagan, Brian G.; Sandborn, William J.; Huttenhower, Curtis; Wortman, Jennifer R.; McGovern, Barbara H.; Wang-Weigand, Sherry; Lichter, David, I; Chafee, Meghan; Ford, Christopher B.; Bernardo, Patricia; Zhao, Peng; Simmons, Sheri; Tomlinson, Amelia D.; Cook, David N.; Pomerantz, Roger J.; Misra, Bharat K.; Aunins, John G.; Trucksis, Michele 分享 收藏
SER-109, an Investigational Microbiome Drug to Reduce Recurrence After Clostridioides difficile Infection: Lessons Learned From a Phase 2 Trial McGovern, Barbara H.; Ford, Christopher B.; Henn, Matthew R.; Pardi, Darrell S.; Khanna, Sahil; Hohmann, Elizabeth L.; O'Brien, Edward J.; Desjardins, Christopher A.; Bernardo, Patricia; Wortman, Jennifer R.; Lombardo, Mary-Jane; Litcofsky, Kevin D.; Winkler, Jonathan A.; McChalicher, Christopher W. J.; Li, Sunny S.; Tomlinson, Amelia D.; Nandakumar, Madhumitha; Cook, David N.; Pomerantz, Roger J.; Aunins, John G.; Trucksis, Michele 分享 收藏
Leveraging gut microbiota networks to impact tumor immunotherapy Sceneay, Jaclyn; Srinivasan, Srimathi; Halley, Keith; Marnellos, George; Wortman, Jennifer; Henn, Matthew; Fink, Elura; Litcofsky, Kevin; Cook, David; Jayaraman, Lata 分享 收藏
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Revitalization of a Forward Genetic Screen Identifies Three New Regulators of Fungal Secondary Metabolism in the Genus Aspergillus Pfannenstiel, Brandon T.; Zhao, Xixi; Wortman, Jennifer; Wiemann, Philipp; Throckmorton, Kurt; Spraker, Joseph E.; Soukup, Alexandra A.; Luo, Xingyu; Lindner, Daniel L.; Lim, Fang Yun; Knox, Benjamin P.; Haas, Brian; Fischer, Gregory J.; Choera, Tsokyi; Butchko, Robert A. E.; Bok, Jin-Woo; Affeldt, Katharyn J.; Keller, Nancy P.; Palmer, Jonathan M. 分享 收藏
Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus 比较基因组学揭示了在工业和医学上重要的真菌曲霉属中的高度生物多样性和特定适应性 de Vries, Ronald P.; Riley, Robert; Wiebenga, Ad; Aguilar-Osorio, Guillermo; Amillis, Sotiris; Uchima, Cristiane Akemi; Anderluh, Gregor; Asadollahi, Mojtaba; Askin, Marion; Barry, Kerrie; Battaglia, Evy; Bayram, Ozgur; Benocci, Tiziano; Braus-Stromeyer, Susanna A.; Caldana, Camila; Canovas, David; Cerqueira, Gustavo C.; Chen, Fusheng; Chen, Wanping; Choi, Cindy; Clum, Alicia; Correa dos Santos, Renato Augusto; de Lima Damasio, Andre Ricardo; Diallinas, George; Emri, Tamas; Fekete, Erzsebet; Flipphi, Michel; Freyberg, Susanne; Gallo, Antonia; Gournas, Christos; Habgood, Rob; Hainaut, Matthieu; Laura Harispe, Maria; Henrissat, Bernard; Hilden, Kristiina S.; Hope, Ryan; Hossain, Abeer; Karabika, Eugenia; Karaffa, Levente; Karanyi, Zsolt; Krasevec, Nada; Kuo, Alan; Kusch, Harald; LaButti, Kurt; Lagendijk, Ellen L.; Lapidus, Alla; Levasseur, Anthony; Lindquist, Erika; Lipzen, Anna; Logrieco, Antonio F.; MacCabe, Andrew; Makela, Miia R.; Malavazi, Iran; Melin, Petter; Meyer, Vera; Mielnichuk, Natalia; Miskei, Marton; Molnar, Akos P.; Mule, Giuseppina; Ngan, Chew Yee; Orejas, Margarita; Orosz, Erzsebet; Ouedraogo, Jean Paul; Overkamp, Karin M.; Park, Hee-Soo; Perrone, Giancarlo; Piumi, Francois; Punt, Peter J.; Ram, Arthur F. J.; Ramon, Ana; Rauscher, Stefan; Record, Eric; Riano-Pachon, Diego Mauricio; Robert, Vincent; Roehrig, Julian; Ruller, Roberto; Salamov, Asaf; Salih, Nadhira S.; Samson, Rob A.; Sandor, Erzsebet; Sanguinetti, Manuel; Schutze, Tabea; Sepcic, Kristina; Shelest, Ekaterina; Sherlock, Gavin; Sophianopoulou, Vicky; Squina, FabioM.; Sun, Hui; Susca, Antonia; Todd, Richard B.; Tsang, Adrian; Unkles, Shiela E.; van de Wiele, Nathalie; van Rossen-Uffink, Diana; de Castro Oliveira, Juliana Velasco; Vesth, Tammi C.; Visser, Jaap; Yu, Jae-Hyuk; Zhou, Miaomiao; Andersen, Mikael R.; Archer, David B.; Baker, Scott E.; Benoit, Isabelle; Brakhage, Axel A.; Braus, Gerhard H.; Fischer, Reinhard; Frisvad, Jens C.; Goldman, Gustavo H.; Houbraken, Jos; Oakley, Berl; Pocsi, Istvan; Scazzocchio, Claudio; Seiboth, Bernhard; vanKuyk, Patricia A.; Wortman, Jennifer; Dyer, Paul S.; Grigoriev, Igor V. 分享 收藏
Multi-institute analysis of carbapenem resistance reveals remarkable diversity, unexplained mechanisms, and limited clonal outbreaks Cerqueira, Gustavo C.; Earl, Ashlee M.; Ernst, Christoph M.; Grad, Yonatan H.; Dekker, John P.; Feldgarden, Michael; Chapman, Sinead B.; Reis-Cunha, Joao L.; Shea, Terrance P.; Young, Sarah; Zeng, Qiandong; Delaney, Mary L.; Kim, Diane; Peterson, Ellena M.; O'Brien, Thomas F.; Ferraro, Mary Jane; Hooper, David C.; Huang, Susan S.; Kirby, James E.; Onderdonk, Andrew B.; Birren, Bruce W.; Hung, Deborah T.; Cosimi, Lisa A.; Wortman, Jennifer R.; Murphy, Cheryl I.; Hanage, William P. 分享 收藏
Structure of the germline genome of Tetrahymena thermophila and relationship to the massively rearranged somatic genome Hamilton, Eileen P.; Kapusta, Aurelie; Huvos, Piroska E.; Bidwell, Shelby L.; Zafar, Nikhat; Tang, Haibao; Hadjithomas, Michalis; Krishnakumar, Vivek; Badger, Jonathan H.; Caler, Elisabet V.; Russ, Carsten; Zeng, Qiandong; Fan, Lin; Levin, Joshua Z.; Shea, Terrance; Young, Sarah K.; Hegarty, Ryan; Daza, Riza; Gujja, Sharvari; Wortman, Jennifer R.; Birren, Bruce W.; Nusbaum, Chad; Thomas, Jainy; Carey, Clayton M.; Pritham, Ellen J.; Feschotte, Cedric; Noto, Tomoko; Mochizuki, Kazufumi; Papazyan, Romeo; Taverna, Sean D.; Dear, Paul H.; Cassidy-Hanley, Donna M.; Xiong, Jie; Miao, Wei; Orias, Eduardo; Coyne, Robert S. 分享 收藏
Genomic and functional analyses of Mycobacterium tuberculosis strains implicate ald in D-cycloserine resistance Desjardins, Christopher A.; Cohen, Keira A.; Munsamy, Vanisha; Abeel, Thomas; Maharaj, Kashmeel; Walker, Bruce J.; Shea, Terrance P.; Almeida, Deepak V.; Manson, Abigail L.; Salazar, Alex; Padayatchi, Nesri; O'Donnell, Max R.; Mlisana, Koleka P.; Wortman, Jennifer; Birren, Bruce W.; Grosset, Jacques; Earl, Ashlee M.; Pym, Alexander S. 分享 收藏
Genomic insights into the Ixodes scapularis tick vector of Lyme disease 莱姆病的肩胛骨蜱媒介的基因组洞察 Gulia-Nuss, Monika; Nuss, Andrew B.; Meyer, Jason M.; Sonenshine, Daniel E.; Roe, R. Michael; Waterhouse, Robert M.; Sattelle, David B.; de la Fuente, Jose; Ribeiro, Jose M.; Megy, Karine; Thimmapuram, Jyothi; Miller, Jason R.; Walenz, Brian P.; Koren, Sergey; Hostetler, Jessica B.; Thiagarajan, Mathangi; Joardar, Vinita S.; Hannick, Linda I.; Bidwell, Shelby; Hammond, Martin P.; Young, Sarah; Zeng, Qiandong; Abrudan, Jenica L.; Almeida, Francisca C.; Ayllon, Nieves; Bhide, Ketaki; Bissinger, Brooke W.; Bonzon-Kulichenko, Elena; Buckingham, Steven D.; Caffrey, Daniel R.; Caimano, Melissa J.; Croset, Vincent; Driscoll, Timothy; Gilbert, Don; Gillespie, Joseph J.; Giraldo-Calderon, Gloria I.; Grabowski, Jeffrey M.; Jiang, David; Khalil, Sayed M. S.; Kim, Donghun; Kocan, Katherine M.; Koci, Juraj; Kuhn, Richard J.; Kurtti, Timothy J.; Lees, Kristin; Lang, Emma G.; Kennedy, Ryan C.; Kwon, Hyeogsun; Perera, Rushika; Qi, Yumin; Radolf, Justin D.; Sakamoto, Joyce M.; Sanchez-Gracia, Alejandro; Severo, Maiara S.; Silverman, Neal; Simo, Ladislav; Tojo, Marta; Tornador, Cristian; Van Zee, Janice P.; Vazquez, Jesus; Vieira, Filipe G.; Villar, Margarita; Wespiser, Adam R.; Yang, Yunlong; Zhu, Jiwei; Arensburger, Peter; Pietrantonio, Patricia V.; Barker, Stephen C.; Shao, Renfu; Zdobnov, Evgeny M.; Hauser, Frank; Grimmelikhuijzen, Cornelis J. P.; Park, Yoonseong; Rozas, Julio; Benton, Richard; Pedra, Joao H. F.; Nelson, David R.; Unger, Maria F.; Tubio, Jose M. C.; Tu, Zhijian; Robertson, Hugh M.; Shumway, Martin; Sutton, Granger; Wortman, Jennifer R.; Lawson, Daniel; Wikel, Stephen K.; Nene, Vishvanath M.; Fraser, Claire M.; Collins, Frank H.; Birren, Bruce; Nelson, Karen E.; Caler, Elisabet; Hill, Catherine A. 分享 收藏
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The Genomic Diversification of the Whole Acinetobacter Genus: Origins, Mechanisms, and Consequences Touchon, Marie; Cury, Jean; Yoon, Eun-Jeong; Krizova, Lenka; Cerqueira, Gustavo C.; Murphy, Cheryl; Feldgarden, Michael; Wortman, Jennifer; Clermont, Dominique; Lambert, Thierry; Grillot-Courvalin, Catherine; Nemec, Alexandr; Courvalin, Patrice; Rocha, Eduardo P. C. 分享 收藏
Identification of 50 Class D β-Lactamases and 65 Acinetobacter-Derived Cephalosporinases in Acinetobacter spp. Perichon, Bruno; Goussard, Sylvie; Walewski, Violaine; Krizova, Lenka; Cerqueira, Gustavo; Murphy, Cheryl; Feldgarden, Michael; Wortman, Jennifer; Clermont, Dominique; Nemec, Alexandr; Courvalin, Patrice 分享 收藏
The Aspergillus Genome Database: multispecies curation and incorporation of RNA-Seq data to improve structural gene annotations Cerqueira, Gustavo C.; Arnaud, Martha B.; Inglis, Diane O.; Skrzypek, Marek S.; Binkley, Gail; Simison, Matt; Miyasato, Stuart R.; Binkley, Jonathan; Orvis, Joshua; Shah, Prachi; Wymore, Farrell; Sherlock, Gavin; Wortman, Jennifer R. 分享 收藏
Emergence of Epidemic Multidrug-Resistant Enterococcus faecium from Animal and Commensal Strains Lebreton, Francois; van Schaik, Willem; McGuire, Abigail Manson; Godfrey, Paul; Griggs, Allison; Mazumdar, Varun; Corander, Jukka; Cheng, Lu; Saif, Sakina; Young, Sarah; Zeng, Qiandong; Wortman, Jennifer; Birren, Bruce; Willems, Rob J. L.; Earl, Ashlee M.; Gilmore, Michael S. 分享 收藏
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