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A novel, centrally acting mammalian aminosterol, ENT-03, induces weight loss in obese and lean rodents Barbut, Denise; Kinney, William A.; Chen, Hsiao-Huei; Stewart, Alexandre F. R.; Hecksher-Sorensen, Jacob; Zhang, Chen; Fleming, Alexander; Zemel, Michael; Zasloff, Michael 分享 收藏
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Early life interventions metformin and trodusquemine metabolically reprogram the developing mouse liver through transcriptomic alterations Ashiqueali, Sarah A.; Schneider, Augusto; Zhu, Xiang; Juszczyk, Ewelina; Mansoor, Mishfak A. M.; Zhu, Yun; Fang, Yimin; Zanini, Bianka M.; Garcia, Driele N.; Hayslip, Natalie; Medina, David; Mcfadden, Samuel; Stockwell, Robert; Yuan, Rong; Bartke, Andrzej; Zasloff, Michael; Siddiqi, Shadab; Masternak, Michal M. 分享 收藏
Squalamine reverses age-associated changes of firing patterns of myenteric sensory neurons and vagal fibres Neufeld, Karen-Anne McVey; Mao, Yu-Kang; West, Christine L.; Ahn, Matthew; Hameed, Hashim; Iwashita, Eiko; Stanisz, Andrew M.; Forsythe, Paul; Barbut, Denise; Zasloff, Michael; Kunze, Wolfgang A. 分享 收藏
Quantitative Attribution of the Protective Effects of Aminosterols against Protein Aggregates to Their Chemical Structures and Ability to Modulate Biological Membranes Errico, Silvia; Lucchesi, Giacomo; Odino, Davide; Osman, Enass Youssef; Cascella, Roberta; Neri, Lorenzo; Capitini, Claudia; Calamai, Martino; Bemporad, Francesco; Cecchi, Cristina; Kinney, William A.; Barbut, Denise; Relini, Annalisa; Canale, Claudio; Caminati, Gabriella; Limbocker, Ryan; Vendruscolo, Michele; Zasloff, Michael; Chiti, Fabrizio 分享 收藏
ENT-03, a Centrally Acting Endogenous Spermine Bile Acid with PTP1B Inhibitory Activity, Has Potent Effects on Metabolism and Weight in a Mouse Model of Diet-Induced Obesity (DIO) Barbut, Denise; Baur, Joseph A.; Titchenell, Paul M.; Davis, James G.; Zemel, Michael B.; Fleming, G. Alexander; Moses, Alan C.; Zasloff, Michael 分享 收藏
Reorganization of the outer layer of a model of the plasma membrane induced by a neuroprotective aminosterol Barletti, Beatrice; Lucchesi, Giacomo; Muscat, Stefano; Errico, Silvia; Barbut, Denise; Danani, Andrea; Zasloff, Michael; Grasso, Gianvito; Chiti, Fabrizio; Caminati, Gabriella 分享 收藏
Oral ENT-01 Targets Enteric Neurons to Treat Constipation in Parkinson Disease: A Randomized Controlled Trial Camilleri, Michael; Subramanian, Thyagarajan; Pagan, Fernando; Isaacson, Stuart; Gil, Ramon; Hauser, Robert A.; Feldman, Mary; Goldstein, Mark; Kumar, Rajeev; Truong, Daniel; Chhabria, Nisha; Walter, Benjamin L.; Eskenazi, Jonathan; Riesenberg, Robert; Burdick, Daniel; Tse, Winona; Molho, Eric; Robottom, Bradley; Bhatia, Perminder; Kadimi, Srinath; Klos, Kevin; Shprecher, David; Marquez-Mendoza, Otto; Hidalgo, Gonzalo; Grill, Stephen; Li, George; Mandell, Howard; Hughes, Mary; Stephenson, Sharisse; Vandersluis, Joel; Pfeffer, Michael; Duker, Andrew; Shivkumar, Vikram; Kinney, William; MacDougall, James; Zasloff, Michael; Barbut, Denise 分享 收藏
Studying the trafficking of labeled trodusquemine and its application as nerve marker for light-sheet and expansion microscopy Capitini, Claudia; Pesce, Luca; Fani, Giulia; Mazzamuto, Giacomo; Genovese, Massimo; Franceschini, Alessandra; Paoli, Paolo; Pieraccini, Giuseppe; Zasloff, Michael; Chiti, Fabrizio; Pavone, Francesco S.; Calamai, Martino 分享 收藏
The Microbiome and Metabolomic Profile of the Transplanted Intestine with Long-Term Function Girlanda, Raffaelle; Liggett, Jedson R.; Jayatilake, Meth; Kroemer, Alexander; Guerra, Juan Francisco; Hawksworth, Jason Solomon; Radkani, Pejman; Matsumoto, Cal S.; Zasloff, Michael; Fishbein, Thomas M. 分享 收藏
A Brain-Permeable Aminosterol Regulates Cell Membranes toMitigate the Toxicity of Diverse Pore-Forming Agents Kreiser, Ryan P.; Wright, Aidan K.; Sasser, Liam R.; Rinauro, Dillon J.; Gabriel, Justus M.; Hsu, Claire M.; Hurtado, Jorge A.; McKenzie, Tristan L.; Errico, Silvia; Albright, J. Alex; Richardson, Lance; Jaffett, Victor A.; Riegner, Dawn E.; Nguyen, Lam T.; LeForte, Kathleen; Zasloff, Michael; Hollows, Jared E.; Chiti, Fabrizio; Vendruscolo, Michele; Limbocker, Ryan 分享 收藏
Alpha synuclein, the culprit in Parkinson disease, is required for normal immune function Alam, Md Masud; Yang, De; Li, Xiao-Qing; Liu, Jia; Back, Timothy Carrel; Trivett, Anna; Karim, Baktiar; Barbut, Denise; Zasloff, Michael; Oppenheim, Joost J. 分享 收藏
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Quantitative Measurement of the Affinity of Toxic and Nontoxic Misfolded Protein Oligomers for Lipid Bilayers and of its Modulation by Lipid Composition and Trodusquemine Errico, Silvia; Ramshini, Hassan; Capitini, Claudia; Canale, Claudio; Spaziano, Martina; Barbut, Denise; Calamai, Martino; Zasloff, Michael; Oropesa-Nunez, Reinier; Vendruscolo, Michele; Chiti, Fabrizio 分享 收藏
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