Paul N. Barlow - Publications, H-index & Citations

Paul N. Barlow

University of Edinburgh

54H指数

264论文数

9.3K被引数

收录论文 112

发表时间

A supernumerary synthetic chromosome in Komagataella phaffii as a repository for extraneous genetic material Komagataella phaffii中的多余合成染色体作为外来遗传物质的储存库

MICROBIAL CELL FACTORIES

IF4.9

2023-12-16

OAAI

Abramczyk, Dariusz; del Carmen Sanchez Olmos, Maria; Rojas, Adan Andres Ramirez; Schindler, Daniel; Robertson, Daniel; McColm, Stephen; Marston, Adele L.; Barlow, Paul N.

An Evaluation of the Complement-Regulating Activities of Human Complement Factor H (FH) Variants Associated With Age-Related Macular Degeneration

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

IF4.7

2022-11-29

OAAI

Biggs, Robyn M.; Makou, Elisavet; Lauder, Scott; Herbert, Andrew P.; Barlow, Paul N.; Katti, Suresh K.

Editorial: Function and Dysfunction of Complement Factor H

FRONTIERS IN IMMUNOLOGY

IF5.9

2022-01-13

OAAI

Jozsi, Mihaly; Barlow, Paul Nigel; Meri, Seppo

Energetics of a protein disorder-order transition in small molecule recognition

CHEMICAL SCIENCE

IF7.4

2022-01-01

OAAI

Mendoza-Martinez, Cesar; Papadourakis, Michail; Llabres, Salome; Gupta, Arun A.; Barlow, Paul N.; Michel, Julien

Murine Factor H Co-Produced in Yeast With Protein Disulfide Isomerase Ameliorated C3 Dysregulation in Factor H-Deficient Mice

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-05-12

OAAI

Kerr, Heather; Herbert, Andrew P.; Makou, Elisavet; Abramczyk, Dariusz; Malik, Talat H.; Lomax-Browne, Hannah; Yang, Yi; Pappworth, Isabel Y.; Denton, Harriet; Richards, Anna; Marchbank, Kevin J.; Pickering, Matthew C.; Barlow, Paul N.

Functional Characterization of Rare Genetic Variants in the N-Terminus of Complement Factor H in aHUS, C3G, and AMD

FRONTIERS IN IMMUNOLOGY

IF5.9

2021-01-14

OAAI

Wong, Edwin K. S.; Hallam, Thomas M.; Brocklebank, Vicky; Walsh, Patrick R.; Smith-Jackson, Kate; Shuttleworth, Victoria G.; Cox, Thomas E.; Anderson, Holly E.; Barlow, Paul Nigel; Marchbank, Kevin James; Harris, Claire L.; Kavanagh, David

Complement inhibitor factor H expressed by breast cancer cells differentiates CD14+ human monocytes into immunosuppressive macrophages

ONCOIMMUNOLOGY

IF6.3

2020-03-06

OAAI

Smolag, Karolina I.; Mueni, Christine M.; Leandersson, Karin; Jirstrom, Karin; Hagerling, Catharina; Morgelin, Matthias; Barlow, Paul N.; Martin, Myriam; Blom, Anna M.

Dynamic design: manipulation of millisecond timescale motions on the energy landscape of cyclophilin A

CHEMICAL SCIENCE

IF7.4

2020-01-01

OAAI

Juarez-Jimenez, Jordi; Gupta, Arun A.; Karunanithy, Gogulan; Mey, Antonia S. J. S.; Georgiou, Charis; Ioannidis, Harris; De Simone, Alessio; Barlow, Paul N.; Hulme, Alison N.; Walkinshaw, Malcolm D.; Baldwin, Andrew J.; Michel, Julien

Combining SPR with atomic-force microscopy enables single-molecule insights into activation and suppression of the complement cascade

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2019-12-01

OAAI

Makou, Elisavet; Bailey, Richard G.; Johnston, Heather; Parkin, John D.; Hulme, Alison N.; Hahner, Georg; Barlow, Paul N.

Hyperfunctional complement C3 promotes C5-dependent atypical hemolytic uremic syndrome in mice

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2019-02-04

OAAI

Smith-Jackson, Kate; Yang, Yi; Denton, Harriet; Pappworth, Isabel, V; Cooke, Katie; Barlow, Paul N.; Atkinson, John P.; Liszewski, M. Kathryn; Pickering, Matthew C.; Kavanagh, David; Cook, H. Terence; Marchbank, Kevin J.

A computationally designed binding mode flip leads to a novel class of potent tri-vector cyclophilin inhibitors

CHEMICAL SCIENCE

IF7.4

2019-01-01

OAAI

De Simone, Alessio; Georgiou, Charis; Ioannidis, Harris; Gupta, Arun A.; Juarez-Jimenez, Jordi; Doughty-Shenton, Dahlia; Blackburn, Elizabeth A.; Wear, Martin A.; Richards, Jonathan P.; Barlow, Paul N.; Carragher, Neil; Walkinshaw, Malcolm D.; Hulme, Alison N.; Michel, Julien

Monitor complement activation in serum by quantitative cross-linking/mass spectrometry

MOLECULAR IMMUNOLOGY

IF3

2018-10-01

PREAI

Chen, Zhuo; Barlow, Paul; Rappsilber, Juri

Genome-Wide Association Studies Identify Disease Mechanisms in Age-Related Macular Degeneration

OPHTHALMOLOGY

IF9.5

2018-07-01

OAAI

Wright, Alan F.; Barlow, Paul N.

Grasping the nettle: A bacterial invasin that targets immunoglobulin variable domains

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2018-06-01

OAAI

Barlow, Paul

Disease-linked mutations in factor H reveal pivotal role of cofactor activity in self-surface-selective regulation of complement activation

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-08-01

OAAI

Kerr, Heather; Wong, Edwin; Makou, Elisavet; Yang, Yi; Marchbank, Kevin; Kavanagh, David; Richards, Anna; Herbert, Andrew P.; Barlow, Paul N.

Structure of Complement C3(H2O) Revealed By Quantitative Cross-Linking/Mass Spectrometry And Modeling

MOLECULAR & CELLULAR PROTEOMICS

IF5.5

2016-08-01

OAAI

Chen, Zhuo A.; Pellarin, Riccardo; Fischer, Lutz; Sali, Andrej; Nilges, Michael; Barlow, Paul N.; Rappsilber, Juri

Comparative Analysis of Novel Complement-Targeted Inhibitors, MiniFH, and the Natural Regulators Factor H and Factor H-like Protein 1 Reveal Functional Determinants of Complement Regulation

JOURNAL OF IMMUNOLOGY

IF3.4

2016-01-15

OAAI

Harder, Markus J.; Anliker, Markus; Hoechsmann, Britta; Simmet, Thomas; Huber-Lang, Markus; Schrezenmeier, Hubert; Ricklin, Daniel; Lambris, John D.; Barlow, Paul N.; Schmidt, Christoph Q.

Complement Evasion Mediated by Enhancement of Captured Factor H: Implications for Protection of Self-Surfaces from Complement

JOURNAL OF IMMUNOLOGY

IF3.4

2015-11-15

OAAI

Herbert, Andrew P.; Makou, Elisavet; Chen, Zhuo A.; Kerr, Heather; Richards, Anna; Rappsilber, Juri; Barlow, Paul N.

Creating functional sophistication from simple protein building blocks, exemplified by factor H and the regulators of complement activation

BIOCHEMICAL SOCIETY TRANSACTIONS

IF4.3

2015-10-09

PREAI

Makou, Elisavet; Herbert, Andrew P.; Barlow, Paul N.

Revealing the Sequence and Resulting Cellular Morphology of Receptor-Ligand Interactions during Plasmodium falciparum Invasion of Erythrocytes 揭示恶性疟原虫入侵红细胞过程中受体-配体相互作用的序列和产生的细胞形态

PLOS PATHOGENS

IF4.9

2015-02-27

245

OAAI

Weiss, Greta E.; Gilson, Paul R.; Taechalertpaisarn, Tana; Tham, Wai-Hong; de Jong, Nienke W. M.; Harvey, Katherine L.; Fowkes, Freya J. I.; Barlow, Paul N.; Rayner, Julian C.; Wright, Gavin J.; Cowman, Alan F.; Crabb, Brendan S.

研究方向