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D

David Rouquié

bayer

19H指数
59论文数
2.1K被引数
收录论文 27
发表时间
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Cell Painting for cytotoxicity and mode-of-action analysis in primary human hepatocytes细胞 Painting 法用于原代人肝细胞的细胞毒性及作用机制分析
errCell Systems
IF7.7
err2026-03-27
err0
errOAAI
errJessica D. Ewald; Katherine L. Titterton; Alex Bäuerle; Alex Beatson; Daniil A. Boiko; Ángel A. Cabrera; Jaime Cheah; Beth A. Cimini; Bram L. Gorissen; Joshua Harrill; Thouis R. Jones; Konrad J. Karczewski; Christine E. Crute; David Rouquie; Srijit Seal; Erin Weisbart; Brandon White; Anne E. Carpenter; Shantanu Singh
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Building trust in the integration of artificial intelligence into chemical risk assessment: findings from the 2024 ECETOC workshop在人工智能融入化学风险评估中的信任构建：2024年ECETOC研讨会的发现
errArchives of Toxicology
IF6.9
err2026-02-17
err0
errOAAI
errTimothy W. Gant; Alistair Boxall; Daniel Burgwinkel; Maryam Zare Jeddi; Ivo Djidrovski; Steffi Friedrichs; Barry Hardy; Thomas Hartung; Daniela Holland; Andreas Karwath; Anne Kienhuis; Nicole Kleinstreuer; Zhoumeng Lin; Emma L. Marczylo; Antonino Marvuglia; Hua Qian; Bennard van Ravenzwaay; Paul Rees; Haralambos Sarimveis; Tewes Tralau; Lucy Wilmot; Adam Zalewski; David Rouquié
err分享
err收藏
The OASIS Consortium: integrating multi-omics technologies to transform chemical safety assessment
errTOXICOLOGICAL SCIENCES
IF4.1
err2025-10-01
err0
errOAAI
errRouquie, David; Bender, Andreas; Cheah, Jaime; Crute, Christine E.; Dalmas, Deidre; Ewald, Jessica; Fullerton, Aaron; Harrill, Joshua A.; Kadri, Sabah; Kleinstreuer, Nicole; Kramer, Nynke; LaRocca, Jessica; Mitchell, Constance A.; Seal, Srijit; Singh, Shantanu; Carpenter, Anne E.
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err收藏
Navigating complexity in modern toxicology: the role of omics in short-term in vivo studies现代毒理学中的复杂性导航：组学在短期体内研究中的作用
errTOXICOLOGICAL SCIENCES
IF4.1
err2025-09-01
err1
errOAAI
errMitchell, Constance A.; Wehmas, Leah; Rouquie, David; Caiment, Florian; Currie, Richard A.; Crute, Christine E.
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Cell morphology and gene expression: tracking changes and complementarity across time and cell lines细胞形态与基因表达：追踪不同时间和细胞系上的变化与互补性
errToxicology and Applied Pharmacology
IF3.4
err2025-08-20
err0
errOAAI
errVanille Lejal; David Rouquié; Olivier Taboureau
err分享
err收藏
Machine Learning for Toxicity Prediction Using Chemical Structures: Pillars for Success in the Real World基于化学结构的毒性预测机器学习：现实世界成功的基石
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2025-05-02
err0
errOAAI
errSeal, Srijit; Mahale, Manas; Garcia-Ortegon, Miguel; Joshi, Chaitanya K.; Hosseini-Gerami, Layla; Beatson, Alex; Greenig, Matthew; Shekhar, Mrinal; Patra, Arijit; Weis, Caroline; Mehrjou, Arash; Badre, Adrien; Paisley, Brianna; Lowe, Rhiannon; Singh, Shantanu; Shah, Falgun; Johannesson, Bjarki; Williams, Dominic; Rouquie, David; Clevert, Djork-Arne; Schwab, Patrick; Richmond, Nicola; Nicolaou, Christos A.; Gonzalez, Raymond J.; Naven, Russell; Schramm, Carolin; Vidler, Lewis R.; Mansouri, Kamel; Walters, W. Patrick; Wilk, Deidre Dalmas; Spjuth, Ola; Carpenter, Anne E.; Bender, Andreas
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Cell Painting and Chemical Structure Read-Across Can Complement Each Other for Rat Acute Oral Toxicity Prediction in Chemical Early Derisking
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2024-11-08
err1
PREAI
errCamilleri, Fabrice; Wenda, Joanna M.; Pecoraro-Mercier, Claire; Comet, Jean-Paul; Rouquie, David
err分享
err收藏
Assessment of Drug-Induced Liver Injury through Cell Morphology and Gene Expression Analysis
errCHEMICAL RESEARCH IN TOXICOLOGY
IF3.8
err2023-08-31
err10
errOAAI
errLejal, Vanille; Cerisier, Natacha; Rouquie, David; Taboureau, Olivier
err分享
err收藏
Applying genomics in regulatory toxicology: a report of the ECETOC workshop on omics threshold on non-adversity
errARCHIVES OF TOXICOLOGY
IF6.9
err2023-06-09
err5
errOAAI
errGant, Timothy W.; Auerbach, Scott S.; Von Bergen, Martin; Bouhifd, Mounir; Botham, Philip A.; Caiment, Florian; Currie, Richard A.; Harrill, Joshua; Johnson, Kamin; Li, Dongying; Rouquie, David; van Ravenzwaay, Ben; Sistare, Frank; Tralau, Tewes; Viant, Mark R.; van de Laan, Jan Willem; Yauk, Carole
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Cell morphology-guided de novo hit design by conditioning GANs on phenotypic image features
errDIGITAL DISCOVERY
IF5.6
err2023-01-01
err12
errOAAI
errZapata, Paula A. Marin; Mendez-Lucio, Oscar; Le, Tuan; Beese, Carsten Joern; Wichard, Joerg; Rouquie, David; Clevert, Djork-Arne
err分享
err收藏
'All In': a pragmatic framework for COVID-19 testing and action on a global scale
errEMBO MOLECULAR MEDICINE
IF8.3
err2020-05-27
err26
errOAAI
errPettit, Syril D.; Jerome, Keith R.; Rouquie, David; Mari, Bernard; Barbry, Pascal; Kanda, Yasunari; Matsumoto, Mineo; Hester, Susan; Wehmas, Leah; Botten, Jason W.; Bruce, Emily A.
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Exploring the Use of Compound-Induced Transcriptomic Data Generated From Cell Lines to Predict Compound Activity Toward Molecular Targets
errFRONTIERS IN CHEMISTRY
IF4.2
err2020-04-23
err17
errOAAI
errBaillif, Benoit; Wichard, Joerg; Mendez-Lucio, Oscar; Rouquie, David
err分享
err收藏
De novo generation of hit-like molecules from gene expression signatures using artificial intelligence使用人工智能从基因表达签名中从头生成hit样分子
errNATURE COMMUNICATIONS
IF15.7
err2020-01-03
err179
errOAAI
errMendez-Lucio, Oscar; Baillif, Benoit; Clevert, Djork-Arne; Rouquie, David; Wichard, Joerg
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Stacked Generalization with Applicability Domain Outperforms Simple QSAR on in Vitro Toxicological Data
errJOURNAL OF CHEMICAL INFORMATION AND MODELING
IF5.3
err2019-02-08
err21
PREAI
errGrenet, Ingrid; Merlo, Kevin; Comet, Jean-Paul; Tertiaux, Romain; Rouquie, David; Dayan, Frederic
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Low dose evaluation of the antiandrogen flutamide following a Mode of Action approach按照作用方式对抗雄激素氟他胺进行低剂量评估
errTOXICOLOGY AND APPLIED PHARMACOLOGY
IF3.4
err2015-12-01
err10
PREAI
errSarrabay, A.; Hilmi, C.; Tinwell, H.; Schorsch, F.; Pallardy, M.; Bars, R.; Rouquie, D.
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Contribution of new technologies to characterization and prediction of adverse effects
errCRITICAL REVIEWS IN TOXICOLOGY
IF4.1
err2015-01-23
err29
PREAI
errRouquie, David; Heneweer, Marjoke; Botham, Jane; Ketelslegers, Hans; Markell, Lauren; Pfister, Thomas; Steiling, Winfried; Strauss, Volker; Hennes, Christa
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Liver tumor formation in female rat induced by fluopyram is mediated by CAR/PXR nuclear receptor activation
errREGULATORY TOXICOLOGY AND PHARMACOLOGY
IF3.5
err2014-12-01
err31
PREAI
errTinwell, H.; Rouquie, D.; Schorsch, F.; Geter, D.; Wason, S.; Bars, R.
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err收藏
Thyroid tumor formation in the male mouse induced by fluopyram is mediated by activation of hepatic CAR/PXR nuclear receptors
errREGULATORY TOXICOLOGY AND PHARMACOLOGY
IF3.5
err2014-12-01
err29
PREAI
errRouquie, D.; Tinwell, H.; Blanck, O.; Schorsch, F.; Geter, D.; Wason, S.; Bars, R.
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A Molecular and Phenotypic Integrative Approach to Identify a No-Effect Dose Level for Antiandrogen-Induced Testicular Toxicity
errTOXICOLOGICAL SCIENCES
IF4.1
err2011-04-27
err19
errOAAI
errLudwig, Sophie; Tinwell, Helen; Schorsch, Frederic; Cavaille, Christel; Pallardy, Marc; Rouquie, David; Bars, Remi
err分享
err收藏
Investigation of endogenous soybean food allergens by using a 2-dimensional gel electrophoresis approach
errREGULATORY TOXICOLOGY AND PHARMACOLOGY
IF3.5
err2010-12-01
err32
PREAI
errRouquie, David; Capt, Annabelle; Eby, William H.; Sekar, Vaithilingam; Herouet-Guicheney, Corinne
err分享
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研究方向

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