Eva‐Maria Mandelkow - Publications, H-index & Citations

Eva‐Maria Mandelkow

Helmholtz Association

98H指数

323论文数

3.8W被引数

收录论文 94

发表时间

Unbiased proteomic profiling reveals the IP3R modulator AHCYL1/IRBIT as a novel interactor of microtubule-associated protein tau

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2022-04-01

OAAI

Wischhof, Lena; Adhikari, Aasha; Mondal, Mrityunjoy; Marsal-Cots, Anaies; Biernat, Jacek; Mandelkow, Eva Maria; Mandelkow, Eckhard; Ehninger, Dan; Nicotera, Pierluigi; Bano, Daniele

RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer's disease

CELL DEATH & DISEASE

IF9.6

2021-06-15

OAAI

Perez-Sisques, Leticia; Sancho-Balsells, Anna; Solana-Balaguer, Julia; Campoy-Campos, Genis; Vives-Isern, Marcel; Soler-Palazon, Ferran; Anglada-Huguet, Marta; Lopez-Toledano, Miguel-Angel; Mandelkow, Eva-Maria; Alberch, Jordi; Giralt, Albert; Malagelada, Cristina

Inhibition of Tau aggregation with BSc3094 reduces Tau and decreases cognitive deficits in rTg4510 mice

ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS

IF6.8

2021-06-01

OAAI

Anglada-Huguet, Marta; Rodrigues, Sara; Hochgrafe, Katja; Mandelkow, Eckhard; Mandelkow, Eva-Maria

A combinatorial native MS and LC-MS/MS approach reveals high intrinsic phosphorylation of human Tau but minimal levels of other key modifications

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2020-12-01

OAAI

Drepper, Friedel; Biernat, Jacek; Kaniyappan, Senthilvelrajan; Meyer, Helmut E.; Mandelkow, Eva Maria; Warscheid, Bettina; Mandelkow, Eckhard

Novel antibody against low-n oligomers of tau protein promotes clearance of tau in cells via lysosomes

ALZHEIMERS & DEMENTIA-TRANSLATIONAL RESEARCH & CLINICAL INTERVENTIONS

IF6.8

2020-10-28

OAAI

Chandupatla, Ram Reddy; Flatley, Andrew; Feederle, Regina; Mandelkow, Eva-Maria; Kaniyappan, Senthilvelrajan

FRET-based Tau seeding assay does not represent prion-like templated assembly of Tau filaments

MOLECULAR NEURODEGENERATION

IF17.5

2020-07-16

OAAI

Kaniyappan, Senthilvelrajan; Tepper, Katharina; Biernat, Jacek; Chandupatla, Ram Reddy; Huebschmann, Sabrina; Irsen, Stephan; Bicher, Sandra; Klatt, Christoph; Mandelkow, Eva-Maria; Mandelkow, Eckhard

Functional networks are impaired by elevated tau-protein but reversible in a regulatable Alzheimer's disease mouse model

MOLECULAR NEURODEGENERATION

IF17.5

2019-03-27

OAAI

Green, Claudia; Sydow, Astrid; Vogel, Stefanie; Anglada-Huguet, Marta; Wiedermann, Dirk; Mandelkow, Eckhard; Mandelkow, Eva-Maria; Hoehn, Mathias

Tau/MAPT disease-associated variant A152T alters tau function and toxicity via impaired retrograde axonal transport

HUMAN MOLECULAR GENETICS

IF3.2

2018-12-26

OAAI

Butler, Victoria J.; Salazar, Dominique A.; Soriano-Castell, David; Alves-Ferreira, Miguel; Dennissen, Frank J. A.; Vohra, Mihir; Oses-Prieto, Juan A.; Li, Kathy H.; Wang, Austin L.; Jing, Beibei; Li, Biao; Groisman, Alex; Gutierrez, Edgar; Mooney, Sean; Burlingame, Alma L.; Ashrafi, Kaveh; Mandelkow, Eva-Maria; Encalada, Sandra E.; Kao, Aimee W.

Reversible Cation-Selective Attachment and Self-Assembly of Human Tau on Supported Brain Lipid Membranes

NANO LETTERS

IF9.1

2018-04-12

OAAI

Mari, Stefania A.; Wegmann, Susanne; Tepper, Katharina; Hyman, Bradley T.; Mandelkow, Eva-Maria; Mandelkow, Eckhard; Mueller, Daniel J.

What is the evidence that tau pathology spreads through prion-like propagation?

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2017-12-19

279

OAAI

Mudher, Amrit; Colin, Morvane; Dujardin, Simon; Medina, Miguel; Dewachter, Ilse; Naini, Seyedeh Maryam Alavi; Mandelkow, Eva-Maria; Mandelkow, Eckhard; Buee, Luc; Goedert, Michel; Brion, Jean-Pierre

Anti-aggregant tau mutant promotes neurogenesis 抗聚集性tau突变体促进神经发生

MOLECULAR NEURODEGENERATION

IF17.5

2017-12-04

OAAI

Joseph, Maria; Anglada-Huguet, Marta; Paesler, Katharina; Mandelkow, Eckhard; Mandelkow, Eva-Maria

Atypical, non-standard functions of the microtubule associated Tau protein

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2017-11-29

155

OAAI

Sotiropoulos, Ioannis; Galas, Marie-Christine; Silva, Joana M.; Skoulakis, Efthimios; Wegmann, Susanne; Maina, Mahmoud Bukar; Blum, David; Sayas, Carmen Laura; Mandelkow, Eva-Maria; Mandelkow, Eckhard; Spillantini, Maria Grazia; Sousa, Nuno; Avila, Jesus; Medina, Miguel; Mudher, Amrit; Buee, Luc

Interplay of pathogenic forms of human tau with different autophagic pathways

AGING CELL

IF7.1

2017-10-12

153

OAAI

Caballero, Benjamin; Wang, Yipeng; Diaz, Antonio; Tasset, Inmaculada; Juste, Yves Robert; Stiller, Barbara; Mandelkow, Eva-Maria; Mandelkow, Eckhard; Cuervo, Ana Maria

Time course of Tau toxicity and pharmacologic prevention in a cell model of Tauopathy

NEUROBIOLOGY OF AGING

IF3.5

2017-09-01

PREAI

Pickhardt, Marcus; Biernat, Jacek; Huebschmann, Sabrina; Dennissen, Frank J. A.; Timm, Thomas; Aho, Annukka; Mandelkow, Eva-Maria; Mandelkow, Eckhard

Axodendritic sorting and pathological missorting of Tau are isoform-specific and determined by axon initial segment architecture

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-07-01

OAAI

Zempel, Hans; Dennissen, Frank J. A.; Kumar, Yatender; Luedtke, Julia; Biernat, Jacek; Mandelkow, Eva-Maria; Mandelkow, Eckhard

Extracellular low-n oligomers of tau cause selective synaptotoxicity without affecting cell viability

ALZHEIMERS & DEMENTIA

IF11.1

2017-05-18

PREAI

Kaniyappan, Senthilvelrajan; Chandupatla, Ram Reddy; Mandelkow, Eva-Maria; Mandelkow, Eckhard

The release and trans-synaptic transmission of Tau via exosomes

MOLECULAR NEURODEGENERATION

IF17.5

2017-01-13

545

OAAI

Wang, Yipeng; Balaji, Varun; Kaniyappan, Senthilvelrajan; Krueger, Lars; Irsen, Stephan; Tepper, Katharina; Chandupatla, RamReddy; Maetzler, Walter; Schneider, Anja; Mandelkow, Eckhard; Mandelkow, Eva-Maria

Prevention of tau increase in cerebrospinal fluid of APP transgenic mice suggests downstream effect of BACE1 inhibition

ALZHEIMERS & DEMENTIA

IF11.1

2016-10-14

PREAI

Schelle, Juliane; Haesler, Lisa M.; Goepfert, Jens C.; Joos, Thomas O.; Vanderstichele, Hugo; Stoops, Erik; Mandelkow, Eva-Maria; Neumann, Ulf; Shimshek, Derya R.; Staufenbiel, Matthias; Jucker, Mathias; Kaeser, Stephan A.

Adenosine A1 receptor antagonist rolofylline alleviates axonopathy caused by human Tau ΔK280

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-09-26

OAAI

Dennissen, Frank J. A.; Anglada-Huguet, Marta; Sydow, Astrid; Mandelkow, Eckhard; Mandelkow, Eva-Maria

MMP-9 and MMP-2 Contribute to Neuronal Cell Death in iPSC Models of Frontotemporal Dementia with MAPT Mutations

STEM CELL REPORTS

IF5.1

2016-09-01

OAAI

Biswas, Md Helal U.; Almeida, Sandra; Lopez-Gonzalez, Rodrigo; Mao, Wenjie; Zhang, Zhijun; Karydas, Anna; Geschwind, Michael D.; Biernat, Jacek; Mandelkow, Eva-Maria; Futai, Kensuke; Miller, Bruce L.; Gao, Fen-Biao

研究方向