Stephen L. Abrams - Publications, H-index & Citations

Effects of the Mutant TP53 Reactivator APR-246 on Therapeutic Sensitivity of Pancreatic Cancer Cells in the Presence and Absence of WT-TP53

IF5.2

2022-07-09

OAAI

McCubrey, James A.; Yang, Li, V; Abrams, Stephen L.; Steelman, Linda S.; Follo, Matilde Y.; Cocco, Lucio; Ratti, Stefano; Martelli, Alberto M.; Augello, Giuseppa; Cervello, Melchiorre

GSK-3β Can Regulate the Sensitivity of MIA-PaCa-2 Pancreatic and MCF-7 Breast Cancer Cells to Chemotherapeutic Drugs, Targeted Therapeutics and Nutraceuticals

IF5.2

2022-02-24

OAAI

Abrams, Stephen L.; Duda, Przemyslaw; Akula, Shaw M.; Steelman, Linda S.; Follo, Matilde L.; Cocco, Lucio; Ratti, Stefano; Martelli, Alberto M.; Montalto, Giuseppe; Emma, Maria Rita; Cervello, Melchiorre; Rakus, Dariusz; Gizak, Agnieszka; McCubrey, James A.

Influences of TP53 and the anti-aging DDR1 receptor in controlling Raf/MEK/ERK and PI3K/Akt expression and chemotherapeutic drug sensitivity in prostate cancer cell lines

IF5.2

2021-04-06

OAAI

Abrams, Stephen L.; Akula, Shaw M.; Meher, Akshaya K.; Steelman, Linda S.; Gizak, Agnieszka; Duda, Przemyslaw; Rakus, Dariusz; Martelli, Alberto M.; Ratti, Stefano; Cocco, Lucio; Montalto, Giuseppe; Cervello, Melchiorre; Ruvolo, Peter; Libra, Massimo; Falzone, Luca; Candido, Saverio; McCubrey, James A.

AGING-US

IF3.9

2020-06-03

OAAI

Chappell, William H.; Candido, Saverio; Abrams, Stephen L.; Akula, Shaw M.; Steelman, Linda S.; Martelli, Alberto M.; Ratti, Stefano; Cocco, Lucio; Cervello, Melchiorre; Montalto, Giuseppe; Nicoletti, Ferdinando; Libra, Massimo; McCubrey, James A.

Targeting GSK3 and Associated Signaling Pathways Involved in Cancer

New landscapes and horizons in hepatocellular carcinoma therapy

IF5.2

2020-04-30

173

OAAI

Duda, Przemyslaw; Akula, Shaw M.; Abrams, Stephen L.; Steelman, Linda S.; Martelli, Alberto M.; Cocco, Lucio; Ratti, Stefano; Candido, Saverio; Libra, Massimo; Montalto, Giuseppe; Cervello, Melchiorre; Gizak, Agnieszka; Rakus, Dariusz; McCubrey, James A.

AGING-US

IF3.9

2020-02-04

OAAI

Cervello, Melchiorre; Emma, Maria R.; Augello, Giuseppa; Cusimano, Antonella; Giannitrapani, Lydia; Soresi, Maurizio; Akula, Shaw M.; Abrams, Stephen L.; Steelman, Linda S.; Gulino, Alessandro; Belmonte, Beatrice; Montalto, Giuseppe; McCubrey, James A.

The therapeutic potential of mTOR inhibitors in breast cancer

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

IF3

2016-05-10

OAAI

Steelman, Linda S.; Martelli, Alberto M.; Cocco, Lucio; Libra, Massimo; Nicoletti, Ferdinando; Abrams, Stephen L.; McCubrey, James A.

p53 expression controls prostate cancer sensitivity to chemotherapy and the MDM2 inhibitor Nutlin-3

Dominant roles of the Raf/MEK/ERK pathway in cell cycle progression, prevention of apoptosis and sensitivity to chemotherapeutic drugs

IF3.4

2014-10-31

108

OAAI

Chappell, William H.; Lehmann, Brian D.; Terrian, David M.; Abrams, Stephen L.; Steelman, Linda S.; McCubrey, James A.

The Raf/MEK/ERK pathway can govern drug resistance, apoptosis and sensitivity to targeted therapy

IF3.4

2014-10-28

OAAI

Steelman, Linda S.; Abrams, Stephen L.; Shelton, John G.; Chappell, William H.; Baesecke, Joerg; Stivala, Franca; Donia, Marco; Nicoletti, Ferdinando; Libra, Massimo; Martelli, Alberto M.; McCubrey, James A.

Involvement of Akt and mTOR in chemotherapeutic and hormonal-based drug resistance and response to radiation in breast cancer cells

IF3.4

2014-10-28

123

OAAI

Abrams, Stephen L.; Steelman, Linda S.; Shelton, John G.; Wong, Ellis W. T.; Chappell, William H.; Baesecke, Joerg; Stivala, Franca; Donia, Marco; Nicoletti, Ferdinando; Libra, Massimo; Martelli, Alberto M.; McCubrey, James A.

Enhancing therapeutic efficacy by targeting non-oncogene addicted cells with combinations of signal transduction inhibitors and chemotherapy

IF3.4

2014-10-28

OAAI

Steelman, Linda S.; Navolanic, Patrick; Chappell, William H.; Abrams, Stephen L.; Wong, Ellis W. T.; Martelli, Alberto M.; Cocco, Lucio; Stivala, Franca; Libra, Massimo; Nicoletti, Ferdinando; Drobot, Lyudmyla B.; Franklin, Richard A.; McCubrey, James A.

Ectopic NGAL expression can alter sensitivity of breast cancer cells to EGFR, Bcl-2, CaM-K inhibitors and the natural plant product berberine

IF3.4

2014-10-28

OAAI

Abrams, Stephen L.; Steelman, Linda S.; Shelton, John G.; Chappell, William; Baesecke, Joerg; Stivala, Franca; Donia, Marco; Nicoletti, Ferdinando; Libra, Massimo; Martelli, Alberto M.; McCubrey, James A.

Inhibition of GSK-3β activity can result in drug and hormonal resistance and alter sensitivity to targeted therapy in MCF-7 breast cancer cells

IF3.4

2014-10-28

OAAI

Chappell, William H.; Abrams, Stephen L.; Franklin, Richard A.; LaHair, Michelle M.; Montalto, Giuseppe; Cervello, Melchiorre; Martelli, Alberto M.; Nicoletti, Ferdinando; Candido, Saverio; Libra, Massimo; Polesel, Jerry; Talamini, Renato; Milella, Michele; Tafuri, Agostino; Steelman, Linda S.; McCubrey, James A.

Multifaceted roles of GSK-3 and Wnt/β-catenin in hematopoiesis and leukemogenesis: opportunities for therapeutic intervention

IF3.4

2014-01-09

OAAI

Sokolosky, Melissa; Chappell, William H.; Stadelman, Kristin; Abrams, Stephen L.; Davis, Nicole M.; Steelman, Linda S.; McCubrey, James A.

Roles of the Ras/Raf/MEK/ERK pathway in leukemia therapy

IF13.4

2013-06-19

229

OAAI

McCubrey, J. A.; Steelman, L. S.; Bertrand, F. E.; Davis, N. M.; Abrams, S. L.; Montalto, G.; D'Assoro, A. B.; Libra, M.; Nicoletti, F.; Maestro, R.; Basecke, J.; Cocco, L.; Cervello, M.; Martelli, A. M.

Targeting the translational apparatus to improve leukemia therapy: roles of the PI3K/PTEN/Akt/mTOR pathway

IF13.4

2011-04-15

252

PREAI

Steelman, L. S.; Franklin, R. A.; Abrams, S. L.; Chappell, W.; Kempf, C. R.; Baesecke, J.; Stivala, F.; Donia, M.; Fagone, P.; Nicoletti, F.; Libra, M.; Ruvolo, P.; Ruvolo, V.; Evangelisti, C.; Martelli, A. M.; McCubrey, J. A.

Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging Raf/MEK/ERK和PI3K/PTEN/Akt/mTOR通路在控制生长和治疗敏感性中的作用-对癌症和衰老的影响

IF13.4

2011-03-25

188

PREAI

Martelli, A. M.; Evangelisti, C.; Chappell, W.; Abrams, S. L.; Baesecke, J.; Stivala, F.; Donia, M.; Fagone, P.; Nicoletti, F.; Libra, M.; Ruvolo, V.; Ruvolo, P.; Kempf, C. R.; Steelman, L. S.; McCubrey, J. A.

AGING-US

IF3.9

2011-03-10

585

OAAI

Steelman, Linda S.; Chappell, William H.; Abrams, Stephen L.; Kempf, C. Ruth; Long, Jacquelyn; Laidler, Piotr; Mijatovic, Sanja; Maksimovic-Ivanic, Danijela; Stivala, Franca; Mazzarino, Maria C.; Donia, Marco; Fagone, Paolo; Malaponte, Graziella; Nicoletti, Ferdinando; Libra, Massimo; Milella, Michele; Tafuri, Agostino; Bonati, Antonio; Baesecke, Joerg; Cocco, Lucio; Evangelisti, Camilla; Martelli, Alberto M.; Montalto, Giuseppe; Cervello, Melchiorre; McCubrey, James A.

Involvement of p53 and Raf/MEK/ERK pathways in hematopoietic drug resistance

Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia

IF13.4

2008-08-07

PREAI

McCubrey, J. A.; Abrams, S. L.; Ligresti, G.; Misaghian, N.; Wong, E. W. T.; Steelman, L. S.; Baesecke, J.; Troppmair, J.; Libra, M.; Nicoletti, F.; Molton, S.; McMahon, M.; Evangelisti, C.; Martelli, A. M.