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Protective autophagy elicited by RAF→MEK→ERK inhibition suggests a treatment strategy for RAS-driven cancers (vol 25, pg 620, 2019) RAF→MEK→ERK抑制所诱发的保护性自噬表明了一种针对RAS驱动型癌症的治疗策略(卷25,页620,2019) Kinsey, Conan G.; Camolotto, Soledad A.; Boespflug, Amelie M.; Guillen, Katrin P.; Foth, Mona; Truong, Amanda; Schuman, Sophia S.; Shea, Jill E.; Seipp, Michael T.; Yap, Jeffrey T.; Burrell, Lance D.; Lum, David H.; Whisenant, Jonathan R.; Gilcrease III, G. Weldon; Cavalieri, Courtney C.; Rehbein, Kaitrin M.; Cutler, Stephanie L.; Affolter, Kajsa E.; Welm, Alana L.; Welm, Bryan E.; Scaife, Courtney L.; Snyder, Eric L.; McMahon, Martin 分享 收藏
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Genetic Silencing of AKT Induces Melanoma Cell Death via mTOR Suppression Parkman, Gennie L.; Turapov, Tursun; Kircher, David A.; Burnett, William J.; Stehn, Christopher M.; O'Toole, Kayla; Culver, Katie M.; Chadwick, Ashley T.; Elmer, Riley C.; Flaherty, Ryan; Stanley, Karly A.; Foth, Mona; Lum, David H.; Judson-Torres, Robert L.; Friend, John E.; Van Brocklin, Matthew W.; McMahon, Martin; Holmen, Sheri L. 分享 收藏
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Activation of NFAT by HGF and IGF-1 via ARF6 and its effector ASAP1 promotes uveal melanoma metastasis (vol 42, pg 2629, 2023) Richards, Jackson R.; Shin, Donghan; Pryor, Rob; Sorensen, Lise K.; Sun, Zhonglou; So, Won Mi; Park, Garam; Wolff, Roger; Truong, Amanda; McMahon, Martin; Grossmann, Allie H.; Harbour, J. William; Zhu, Weiquan; Odelberg, Shannon J.; Yoo, Jae Hyuk 分享 收藏
Activation of NFAT by HGF and IGF-1 via ARF6 and its effector ASAP1 promotes uveal melanoma metastasis Richards, Jackson R.; Shin, Donghan; Pryor, Rob; Sorensen, Lise K.; Sun, Zhonglou; So, Won Mi; Park, Garam; Wolff, Roger; Truong, Amanda; McMahon, Martin; Grossmann, Allie H.; Harbour, J. William; Zhu, Weiquan; Odelberg, Shannon J.; Yoo, Jae Hyuk 分享 收藏
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Newer generation mTOR inhibition represents effective therapeutic strategy for BRAF-mutant melanoma Parkman, Gennie L.; Turapov, Tursun; Kircher, David; Burnett, William; Stehn, Christopher; O'Toole, Kayla; Culver, Katie; Chadwick, Ashley; Elmer, Riley; Flaherty, Ryan; Foth, Mona; Stanley, Karly; Andtbacka, Robert; Lum, David; Judson-Torres, Robert; McMahon, Martin; Holmen, Sheri 分享 收藏
c-MYC mediated resistance to trametinib plus hydroxychloroquine in pancreatic cancer is overcome by CDK4/6 and lysosomal inhibition Silvis, Mark; Silva, Dilru; Riley, Rohweder; Schuman, Sophia; Gudipaty, Swapna; Truong, Amanda; Yap, Jeffery; Affolter, Kajsa; McMahon, Martin; Kinsey, Conan 分享 收藏
Rapid phosphorylation of Ets-2 accompanies mitogen-activated protein kinase activation and the induction of heparin-binding epidermal growth factor gene expression by oncogenic Raf-1 McCarthy, SA; Chen, D; Yang, BS; Ramirez, JJG; Cherwinski, H; Chen, XR; Klagsbrun, M; Hauser, CA; Ostrowski, MC; McMahon, M 分享 收藏
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Persistent activation of mitogen-activated protein kinases p42 and p44 and ets-2 phosphorylation in response to colony-stimulating Factor 1/c-fms Signaling Fowles, LF; Martin, ML; Nelsen, L; Stacey, KJ; Redd, D; Clark, YM; Nagamine, Y; McMahon, M; Hume, DA; Ostrowski, MC 分享 收藏