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Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis 肝细胞TLR4触发肝细胞间Jagged1/Notch信号以确定NASH诱导的纤维化 Yu, Junjie; Zhu, Changyu; Wang, Xiaobo; Kim, KyeongJin; Bartolome, Alberto; Dongiovanni, Paola; Yates, Katherine P.; Valenti, Luca; Carrer, Michele; Sadowski, Thorsten; Qiang, Li; Tabas, Ira; Lavine, Joel E.; Pajvani, Utpal B. 分享 收藏
Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice Hohl, Mathias; Mayr, Manuel; Lang, Lisa; Nickel, Alexander G.; Barallobre-Barreiro, Javier; Yin, Xiaoke; Speer, Thimoteus; Selejan, Simina-Ramona; Goettsch, Claudia; Erb, Katharina; Fecher-Trost, Claudia; Reil, Jan-Christian; Linz, Benedikt; Ruf, Sven; Huebschle, Thomas; Maack, Christoph; Boehm, Michael; Sadowski, Thorsten; Linz, Dominik 分享 收藏
ADA Presidents' Select Abstract: Pyruvate Kinase M2 Overexpression in Podocytes Ameliorates Nephropathy in Diabetic Mice Shinjo, Takanori; St-Louis, Ronald; Fu, Jialin; Park, Kyoungmin; Li, Qian; Yokomizo, Hisashi; Yu, Marc Gregory; Wang, Haiyan; Kannt, Aimo; Sadowski, Thorsten; King, George L. 分享 收藏
Characterization of Glycolytic Enzymes and Pyruvate Kinase M2 in Type 1 and 2 Diabetic Nephropathy Gordin, Daniel; Shah, Hetal; Shinjo, Takanori; St-Louis, Ronald; Qi, Weier; Park, Kyoungmin; Paniagua, Samantha M.; Pober, David M.; Wu, I-Hsien; Bahnam, Vanessa; Brissett, Megan J.; Tinsley, Liane J.; Dreyfuss, Jonathan M.; Pan, Hui; Dong, Yutong; Niewczas, Monika A.; Amenta, Peter; Sadowski, Thorsten; Kannt, Aimo; Keenan, Hillary A.; King, George L. 分享 收藏
Activation of PKM2 Protects against Diabetic Kidney Disease from Mice to Men Gordin, Daniel; Shinjo, Takanori; St-Louis, Ronald; Qi, Weier; Tinsley, Liane J.; Pober, David M.; Brissett, Megan J.; Niewczas, Monika; Dreyfuss, Jonathan; Pan, Hui; Sadowski, Thorsten; Kannt, Aimo; Shah, Hetal; Keenan, Hillary A.; Krolewski, Andrzej; King, George L. 分享 收藏
Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction Qi, Weier; Keenan, Hillary A.; Li, Qian; Ishikado, Atsushi; Kannt, Aimo; Sadowski, Thorsten; Yorek, Mark A.; Wu, I-Hsien; Lockhart, Samuel; Coppey, Lawrence J.; Pfenninger, Anja; Liew, Chong Wee; Qiang, Guifen; Burkart, Alison M.; Hastings, Stephanie; Pober, David; Cahill, Christopher; Niewczas, Monika A.; Israelsen, William J.; Tinsley, Liane; Stillman, Isaac E.; Amenta, Peter S.; Feener, Edward P.; Heiden, Matthew G. Vander; Stanton, Robert C.; King, George L. 分享 收藏
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Cathepsin A inhibition attenuates myocardial infarction-induced heart failure on the functional and proteomic levels Petrera, Agnese; Gassenhuber, Johann; Ruf, Sven; Gunasekaran, Deepika; Esser, Jennifer; Shahinian, Jasmin Hasmik; Huebschle, Thomas; Ruetten, Hartmut; Sadowski, Thorsten; Schilling, Oliver 分享 收藏
Long-term severe diabetes only leads to mild cardiac diastolic dysfunction in Zucker diabetic fatty rats Daniels, Anneleen; Linz, Dominik; van Bilsen, Marc; Ruetten, Hartmut; Sadowski, Thorsten; Ruf, Sven; Juretschke, Hans-Paul; Neumann-Haefelin, Claudia; Munts, Chantal; van der Vusse, Ger J.; van Nieuwenhoven, Frans A. 分享 收藏
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Novel β-Amino Acid Derivatives as Inhibitors of Cathepsin A Ruf, Sven; Buning, Christian; Schreuder, Herman; Horstick, Georg; Linz, Wolfgang; Olpp, Thomas; Pernerstorfer, Josef; Hiss, Katrin; Kroll, Katja; Kannt, Aimo; Kohlmann, Markus; Linz, Dominik; Huebschle, Thomas; Ruetten, Hartmut; Wirth, Klaus; Schmidt, Thorsten; Sadowski, Thorsten 分享 收藏
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Cellular cholesterol depletion triggers shedding of the human interleukin-6 receptor by ADAM10 and ADAM17 (TACE) Matthews, V; Schuster, B; Schütze, S; Bussmeyer, I; Ludwig, A; Hundhausen, C; Sadowski, T; Saftig, P; Hartmann, D; Kallen, KJ; Rose-John, S 分享 收藏
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