P. John Hart - Publications, H-index & Citations

P. John Hart

university at buffalo

51H指数

212论文数

8.0K被引数

收录论文 71

发表时间

Factors Governing the Cross-Species Virulence of Shiga Toxin-Producing Escherichia coli 影响产志贺毒素大肠杆菌种间毒力的因素

Pathogens

IF3.3

2026-04-05

OAAI

Paul Hart; Alexander Bowitch; Alexander Mellmann; Denise M. Ferkey; Gerald B. Koudelka

Activation of human RNA lariat debranching enzyme Dbr1 by binding protein TTDN1 occurs though an intrinsically disordered C-terminal domain

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2023-09-01

OAAI

Clark, Nathaniel E.; Katolik, Adam; Gallant, Pascal; Welch, Anastasia; Murphy, Eileen; Buerer, Luke; Schorl, Christoph; Naik, Nandita; Naik, Mandar T.; Holloway, Stephen P.; Cano, Kristin; Weintraub, Susan T.; Howard, Katherine M.; Hart, P. John; Jogl, Gerwald; Damha, Masad J.; Fairbrother, William G.

Why does oxamniquine kill Schistosoma mansoni and not S. haematobium and S. japonicum?

INTERNATIONAL JOURNAL FOR PARASITOLOGY-DRUGS AND DRUG RESISTANCE

IF3.4

2020-08-01

OAAI

Rugel, Anastasia R.; Guzman, Meghan A.; Taylor, Alexander B.; Chevalier, Frederic D.; Tarpley, Reid S.; McHardy, Stanton F.; Cao, Xiaohang; Holloway, Stephen P.; Anderson, Timothy J. C.; Hart, P. John; LoVerde, Philip T.

A pH Switch Controls Zinc Binding in Tomato Copper-Zinc Superoxide Dismutase

FASEB JOURNAL

IF4.2

2020-04-20

PREAI

Galaleldeen, Ahmad; Taylor, Alexander; Hart, P.

Oxamniquine resistance alleles are widespread in Old World Schistosoma mansoni and predate drug deployment

PLOS PATHOGENS

IF4.9

2019-10-25

OAAI

Chevalier, Frederic D.; Le Clec'h, Winka; McDew-White, Marina; Menon, Vinay; Guzman, Meghan A.; Holloway, Stephen P.; Cao, Xiaohang; Taylor, Alexander B.; Kinung'hi, Safari; Gouvras, Anouk N.; Webster, Bonnie L.; Webster, Joanne P.; Emery, Aidan M.; Rollinson, David; Garba Djirmay, Amadou; Al Mashikhi, Khalid M.; Al Yafae, Salem; Idris, Mohamed A.; Mone, Helene; Mouahid, Gabriel; Hart, P. John; LoVerde, Philip T.; Anderson, Timothy J. C.

Localized Induction of Wild-Type and Mutant Alpha-Synuclein Aggregation Reveals Propagation along Neuroanatomical Tracts

JOURNAL OF VIROLOGY

IF3.8

2018-09-15

OAAI

Ayers, Jacob I.; Riffe, Cara J.; Sorrentino, Zachary A.; Diamond, Jeffrey; Fagerli, Eric; Brooks, Mieu; Galaleldeen, Ahmad; Hart, P. John; Giasson, Benoit I.

Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents

ACS MEDICINAL CHEMISTRY LETTERS

IF4

2018-09-14

OAAI

Rugel, Anastasia; Tarpley, Reid S.; Lopez, Ambrosio; Menard, Travis; Guzman, Meghan A.; Taylor, Alexander B.; Cao, Xiaohang; Kovalskyy, Dmytro; Chevalier, Frederic D.; Anderson, Timothy J. C.; Hart, P. John; LoVerde, Philip T.; McHardy, Stanton F.

A polymeric immunoglobulin-antigen fusion protein strategy for enhancing vaccine immunogenicity

PLANT BIOTECHNOLOGY JOURNAL

IF10.5

2018-07-21

OAAI

Webster, Gina R.; van Dolleweerd, Craig; Guerra, Thais; Stelter, Szymon; Hofmann, Sven; Kim, Mi-Young; Teh, Audrey Y-H.; Diogo, Gil Reynolds; Copland, Alastair; Paul, Mathew J.; Hart, Peter; Reljic, Rajko; Ma, Julian K-C.

Mycoplasma pneumoniae Community-Acquired Respiratory Distress Syndrome Toxin Uses a Novel KELED Sequence for Retrograde Transport and Subsequent Cytotoxicity

MBIO

IF4.7

2018-03-07

OAAI

Ramasamy, Kumaraguruparan; Balasubramanian, Sowmya; Manickam, Krishnan; Pandranki, Lavanya; Taylor, Alexander B.; Hart, P. John; Baseman, Joel B.; Kannan, T. R.

Not Just Ionic Mimicry: Biophysics of Toxic Metal Ion Interactions with Peripheral Membrane Targets

BIOPHYSICAL JOURNAL

IF3.1

2018-02-01

OAAI

Igumenova, Tatyana I.; Cole, Taylor R.; Katti, Sachin; Morales, Krystal A.; Erickson, Samuel G.; Sung, Min Woo; Nyenhuis, Sarah B.; Taylor, Alexander B.; Hart, P. John; Holzenburg, Andreas; Cafiso, David S.

Structural and Kinetic Characterization of High-Affinity Lead(II)-Synaptotagmin I Interactions

BIOPHYSICAL JOURNAL

IF3.1

2018-02-01

OAAI

Katti, Sachin; Her, Bin; Srivastava, Atul; Taylor, Alexander B.; Hart, P. John; Lockless, Steve; Igumenova, Tatyana

Murine IL-4Δ2 splice variant down-regulates IL-4 activities independently of IL-4Rα binding and STAT-6 phosphorylation

CYTOKINE

IF3.7

2017-11-01

PREAI

Diogo, Gil R.; Sparrow, Adam; Paul, Matthew J.; Copland, Alastair; Hart, Peter J.; Stelter, Szymon; van Dolleweerd, Craig; Drake, Pascal M. W.; Macallan, Derek C.; Reljic, Rajko

Unveiling a Drift Resistant Cryptotope within Marburgvirus Nucleoprotein Recognized by Llama Single-Domain Antibodies

FRONTIERS IN IMMUNOLOGY

IF5.9

2017-10-02

OAAI

Garza, John Anthony; Taylor, Alexander Bryan; Sherwood, Laura Jo; Hart, Peter John; Hayhurst, Andrew

Structural and enzymatic insights into species-specific resistance to schistosome parasite drug therapy

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-07-01

OAAI

Taylor, Alexander B.; Roberts, Kenneth M.; Cao, Xiaohang; Clark, Nathaniel E.; Holloway, Stephen P.; Donati, Enrica; Polcaro, Chiara M.; Pica-Mattoccia, Livia; Tarpley, Reid S.; McHardy, Stanton F.; Cioli, Donato; LoVerde, Philip T.; Fitzpatrick, Paul F.; Hart, P. John

Copper-zinc superoxide dismutase is activated through a sulfenic acid intermediate at a copper ion entry site

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-07-01

OAAI

Fetherolf, Morgan M.; Boyd, Stefanie D.; Taylor, Alexander B.; Kim, Hee Jong; Wohlschlegel, James A.; Blackburn, Ninian J.; Hart, P. John; Winge, Dennis R.; Winkler, Duane D.

Structure-Based Design and Synthesis of Potent and Selective Matrix Metalloproteinase 13 Inhibitors

JOURNAL OF MEDICINAL CHEMISTRY

IF6.8

2017-06-27

OAAI

Choi, Jun Yong; Fuerst, Rita; Knapinska, Anna M.; Taylor, Alexander B.; Smith, Lyndsay; Cao, Xiaohang; Hart, P. John; Fields, Gregg B.; Roush, William R.

An engineered transforming growth factor β (TGF-β) monomer that functions as a dominant negative to block TGF-β signaling 一种工程转化生长因子 β (tgf-β) 单体，其功能是阻断tgf-β 信号传导的显性负性

JOURNAL OF BIOLOGICAL CHEMISTRY

IF3.9

2017-04-01

OAAI

Kim, Sun Kyung; Barron, Lindsey; Hinck, Cynthia S.; Petrunak, Elyse M.; Cano, Kristin E.; Thangirala, Avinash; Iskra, Brian; Brothers, Molly; Vonberg, Machell; Leal, Belinda; Richter, Blair; Kodali, Ravindra; Taylor, Alexander B.; Du, Shoucheng; Barnes, Christopher O.; Sulea, Traian; Calero, Guillermo; Hart, P. John; Hart, Matthew J.; Demeler, Borries; Hinck, Andrew P.

Fluorescent Branched RNAs for High-Throughput Analysis of Dbr1 Enzyme Kinetics and Inhibition

ACS CHEMICAL BIOLOGY

IF3.8

2017-01-18

PREAI

Katolik, Adam; Clark, Nathaniel E.; Tago, Nobuhiro; Montemayor, Eric J.; Hart, P. John; Damha, Masad J.

Metal dependence and branched RNA cocrystal structures of the RNA lariat debranching enzyme Dbr1

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2016-12-06

OAAI

Clark, Nathaniel E.; Katolik, Adam; Roberts, Kenneth M.; Taylor, Alexander B.; Holloway, Stephen P.; Schuermann, Jonathan P.; Montemayor, Eric J.; Stevens, Scott W.; Fitzpatrick, Paul F.; Damha, Masad J.; Hart, P. John

Distinct conformers of transmissible misfolded SOD1 distinguish human SOD1-FALS from other forms of familial and sporadic ALS

ACTA NEUROPATHOLOGICA

IF9.3

2016-10-04

OAAI

Ayers, Jacob I.; Diamond, Jeffrey; Sari, Adriana; Fromholt, Susan; Galaleldeen, Ahmad; Ostrow, Lyle W.; Glass, Jonathan D.; Hart, P. John; Borchelt, David R.

研究方向