未登录Two distinct fetal-type signatures characterize juvenile myelomonocytic leukemia两种不同的胎儿型特征谱可表征幼年型髓单核细胞白血病
Strullu, Marion; Arfeuille, Chloe; Caye-Eude, Aurelie; Maillard, Loic; Lainey, Elodie; Piques, Florian; Cassinat, Bruno; Guimiot, Fabien; Dalle, Jean-Hugues; Baruchel, Andre; Chomienne, Christine; Bonnet, Dominique; Souyri, Michele; Cave, Helene .png)
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收藏Comprehensive analysis of mesenchymal cells reveals a dysregulated TGF-β/WNT/ HOXB7 axis in patients with myelofibrosisGanesan, Saravanan; Awan-Toor, Sarah; Guidez, Fabien; Maslah, Nabih; Rahimy, Rifkath; Aoun, Celine; Gou, Panhong; Guiguen, Chloe; Soret, Juliette; Ravdan, Odonchimeg; Bisio, Valeria; Dulphy, Nicolas; Lobry, Camille; Schlageter, Marie-Helene; Souyri, Michele; Giraudier, Stephane; Kiladjian, Jean-Jacques; Chomienne, Christine; Cassinat, Bruno 分享 收藏 Immunotherapy with pVAX14 Nucleic Acid in Combination with All-Trans Retinoic Acid (ATRA) in an Acute Promyelocytic Leukemia (APL) Mouse Model Activates Cytotoxic T-Cells and Enhances Immune Responses: A Strategy for Turning Cold Tumors HotpVAX14核酸免疫疗法联合全反式维甲酸（ATRA）在急性早幼粒细胞白血病（APL）小鼠模型中激活细胞毒性T细胞并增强免疫应答：一种将冷肿瘤转变为热肿瘤的策略Padua, Rose Ann; Patel, Satyananda; Smith, James; Omidvar, Dr; Tekin, Nilgun; Guidez, Fabien; Chiquet, Mathieu; Setterblad, Niclas; Mills, Ken, I; Pla, Marika; Krief, Patricia; Huet, Thierry; Chomienne, Christine; Fenaux, Pierre 分享 收藏 Engaging European society at the forefront of cancer research and care How discussions at the 5th Gago Conference on European Science policy led to the Heidelberg Manifesto让欧洲社会参与癌症研究和护理的最前沿第五届加戈欧洲科学政策会议的讨论如何导致海德堡宣言Baumann, Michael; Celis, Julio; Ringborg, Ulrik; Heitor, Manuel; Berns, Anton; Albreht, Tit; Arabadjiev, Jeliazko; Boutros, Michael; Brandenburg, Mario; Canhao, Helena; Carneiro, Fatima; Chomienne, Christine; De Lorenzo, Francesco; Eggermont, Alexander M. M.; Font, Angel; Garralda, Elena; Goulart, Margarida; Henrique, Rui; Lawler, Mark; Maier-Hein, Lena; Meunier, Francoise; Oberst, Simon; Oliveira, Pedro; Papatriantafyllou, Maria; Schuez, Joachim; Solary, Eric; Valencia, Alfonso; Vargas, Rosalia; Weiderpass, Elisabete; Wilking, Nils 分享 收藏 New Role for Granulocyte Colony-Stimulating Factor-Induced Extracellular Signal-Regulated Kinase 1/2 in Histone Modification and Retinoic Acid Receptor α Recruitment to Gene Promoters: Relevance to Acute Promyelocytic Leukemia Cell DifferentiationCassinat, B.; Zassadowski, F.; Ferry, C.; Llopis, L.; Bruck, N.; Lainey, E.; Duong, V.; Cras, A.; Despouy, G.; Chourbagi, O.; Beinse, G.; Fenaux, P.; Egly, C. Rochette; Chomienne, C. 分享 收藏 New Role for Granulocyte Colony-Stimulating Factor-Induced Extracellular Signal-Regulated Kinase 1/2 in Histone Modification and Retinoic Acid Receptor α Recruitment to Gene Promoters: Relevance to Acute Promyelocytic Leukemia Cell Differentiation (vol 31, pg 1409, 2011)Cassinat, B.; Zassadowski, F.; Ferry, C.; Llopis, L.; Bruck, N.; Lainey, E.; Duong, V.; Cras, A.; Despouy, G.; Chourbagi, O.; Beinse, G.; Fenaux, P.; Egly, C. Rochette; Chomienne, C. 分享 收藏 The Benzene Hematotoxic and Reactive Metabolite 1,4-Benzoquinone Impairs the Activity of the Histone Methyltransferase SET Domain Containing 2 (SETD2) and Causes Aberrant Histone H3 Lysine 36 Trimethylation (H3K36me3)Berthelet, Jeremy; Michail, Christina; Bui, Linh-Chi; Le Coadou, Louise; Sirri, Valentina; Wang, Li; Dulphy, Nicolas; Dupret, Jean-Marie; Chomienne, Christine; Guidez, Fabien; Rodrigues-Lima, Fernando 分享 收藏 PLZF Acetylation Levels Regulate NKT Cell DifferentiationKlibi, Jihene; Joseph, Claudine; Delord, Marc; Teissandier, Aurelie; Lucas, Bruno; Chomienne, Christine; Toubert, Antoine; Bourc'his, Deborah; Guidez, Fabien; Benlagha, Kamel 分享 收藏 Anemia and hemodilution: analysis of a single center cohort based on 2,858 red cell mass measurementsDrevon, Louis; Maslah, Nabih; Soret-Dulphy, Juliette; Dosquet, Christine; Ravdan, Odno; Vercellino, Laetitia; Belkhodja, Ceprimelia; Parquet, Nathalie; Brignier, Anne C.; Schlageter, Marie-Helene; Cassinat, Bruno; Kiladjian, Jean-Jacques; Chomienne, Christine; Giraudier, Stephane 分享 收藏 Human CREBBP acetyltransferase is impaired by etoposide quinone, an oxidative and leukemogenic metabolite of the anticancer drug etoposide through modification of redox-sensitive zinc-finger cysteine residues人CREBBP乙酰转移酶受到依托泊苷醌的损害，依托泊苷醌是抗癌药物依托泊苷的氧化和白血病代谢产物，通过修饰氧化还原敏感的锌指半胱氨酸残基Zhang, Wenchao; Berthelet, Jeremy; Michail, Christina; Bui, Linh-Chi; Gou, Panhong; Liu, Rongxing; Duval, Romain; Renault, Justine; Dupret, Jean-Marie; Guidez, Fabien; Chomienne, Christine; Lima, Fernando Rodrigues 分享 收藏 分享 收藏 分享 收藏 Despite mutation acquisition in hematopoietic stem cells, JMML-propagating cells are not always restricted to this compartment (vol 32, pg 798, 2020)Caye, Aurelie; Rouault-Pierre, Kevin; Strullu, Marion; Lainey, Elodie; Abarrategi, Ander; Fenneteau, Odile; Arfeuille, Chloe; Osman, Jennifer; Cassinat, Bruno; Pereira, Sabrina; Anjos-Afonso, Fernando; Currie, Erin; Ariza-McNaughton, Linda; Barlogis, Vincent; Dalle, Jean-Hugues; Baruchel, Andre; Chomienne, Christine; Cave, Helene; Bonnet, Dominique 分享 收藏 Feasibility of high-throughput sequencing in clinical routine cancer care: lessons from the cancer pilot project of the France Genomic Medicine 2025 planAuzanneau, Celine; Bacq, Delphine; Bellera, Carine; Blons, Helene; Boland, Anne; Boucheix, Marlene; Bourdon, Aurelien; Chollet, Emmanuelle; Chomienne, Christine; Deleuze, Jean-Francois; Delmas, Christelle; Dinart, Derek; Esperou, Helene; Geillon, Flore; Geneste, Damien; Italiano, Antoine; Jean, Delphine; Khalifa, Emmanuel; Laizet, Yec'han; Laurent-Puig, Pierre; Lethimonnier, Franck; Levy-Marchal, Claire; Lucchesi, Carlo; Malle, Carine; Mancini, Pierre; Mathoulin-Pelissier, Simone; Meyer, Vincent; Marie-Ange, Palomares; Perkins, Geraldine; Sellan-Albert, Sabrina; Soubeyran, Isabelle; Wallet, Cedric 分享 收藏 Despite mutation acquisition in hematopoietic stem cells, JMML-propagating cells are not always restricted to this compartmentCaye, Aurelie; Rouault-Pierre, Kevin; Strullu, Marion; Lainey, Elodie; Abarrategi, Ander; Fenneteau, Odile; Arfeuille, Chloe; Osman, Jennifer; Cassinat, Bruno; Pereira, Sabrina; Anjos-Afonso, Fernando; Currie, Erin; Ariza-McNaughton, Linda; Barlogis, Vincent; Dalle, Jean-Hugues; Baruchel, Andre; Chomienne, Christine; Cave, Helene; Bonnet, Dominique 分享 收藏 Masked polycythemia vera: analysis of a single center cohort of 2480 red cell massesMaslah, Nabih; Soret, Juliette; Dosquet, Christine; Vercellino, Laetitia; Belkhodja, Celia; Schlageter, Marie-Helene; Cassinat, Bruno; Kiladjian, Jean-Jacques; Chomienne, Christine; Giraudier, Stephane 分享 收藏 T-Cell Protein Tyrosine Phosphatase Is Irreversibly Inhibited by Etoposide-Quinone, a Reactive Metabolite of the Chemotherapy Drug EtoposideNian, Qing; Berthelet, Jeremy; Zhang, Wenchao; Bui, Linh-Chi; Liu, Rongxing; Xu, Ximing; Duval, Romain; Ganesan, Saravanan; Leger, Thibaut; Chomienne, Christine; Busi, Florent; Guidez, Fabien; Dupret, Jean-Marie; Lima, Fernando Rodrigues 分享 收藏 Benzoquinone, a leukemogenic metabolite of benzene, catalytically inhibits the protein tyrosine phosphatase PTPN2 and alters STAT1 signalingDuval, Romain; Bui, Linh-Chi; Mathieu, Cecile; Nian, Qing; Berthelet, Jeremy; Xu, Ximing; Haddad, Iman; Vinh, Joelle; Duprey, Jean-Marie; Busi, Florent; Guidez, Fabien; Chomienne, Christine; Rodrigues-Lima, Fernando 分享 收藏 CD117hi expression identifies a human fetal hematopoietic stem cell population with high proliferation and self-renewal potentialMaillard, Loic; Sanfilippo, Sandra; Domenech, Carine; Kasmi, Nassima; Petit, Laurence; Jacques, Sebastien; Delezoide, Anne-Lise; Guimiot, Fabien; Eladak, Soria; Moison, Delphine; Nicolas, Nour; Rouiller-Fabre, Virginie; Pozzi-Godin, Stephanie; Mennesson, Benoit; Brival, Marie-Laure; Letourneur, Franck; Jaffredo, Thierry; Chomienne, Christine; Souyri, Michele 分享 收藏 Ropeginterferon alpha-2b targets JAK2V617F-positive polycythemia vera cells in vitro and in vivoVerger, Emmanuelle; Soret-Dulphy, Juliette; Maslah, Nabih; Roy, Lydia; Rey, Jerome; Ghrieb, Zineb; Kralovics, Robert; Gisslinger, Heinz; Grohmann-Izay, Barbara; Klade, Christoph; Chomienne, Christine; Giraudier, Stephane; Cassinat, Bruno; Kiladjian, Jean-Jacques 分享 收藏 
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