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The efficacy of combination treatment with elotuzumab and lenalidomide is dependent on crosstalk between natural killer cells, monocytes and myeloma cells Richardson, Kelden; Keam, Simon P.; Zhu, Joe Jiang; Meyran, Deborah; D'Souza, Criselle; Macdonald, Sean; Campbell, Kerry; Robbins, Michael; Bezman, Natalie A.; Todd, Kirsten; Quach, Hang; Ritchie, David S.; Harrison, Simon J.; Prince, H. Miles; Trapani, Joseph A.; Jenkins, Misty R.; Beavis, Paul A.; Darcy, Phillip K.; Neeson, Paul J. 分享 收藏
Myeloma natural killer cells are exhausted and have impaired regulation of activation D'Souza, Criselle; Keam, Simon P.; Yeang, Han Xian Aw; Neeson, Michael; Richardson, Kelden; Hsu, Andy K.; Canfield, Rachael; Bezman, Natalie; Robbins, Michael; Quach, Hang; Ritchie, David S.; Harrison, Simon J.; Trapani, Joseph A.; Prince, H. Miles; Beavis, Paul A.; Darcy, Phillip K.; Neeson, Paul J. 分享 收藏
Elotuzumab plus Pomalidomide and Dexamethasone for Multiple Myeloma Dimopoulos, Meletios A.; Dytfeld, Dominik; Grosicki, Sebastian; Moreau, Philippe; Takezako, Naoki; Hori, Mitsuo; Leleu, Xavier; LeBlanc, Richard; Suzuki, Kenshi; Raab, Marc S.; Richardson, Paul G.; McKiver, Mihaela Popa; Jou, Ying-Ming; Shelat, Suresh G.; Robbins, Michael; Rafferty, Brian; San-Miguel, Jesus 分享 收藏
Antibody-Dependent Cellular Phagocytosis by Macrophages is a Novel Mechanism of Action of Elotuzumab Kurdi, Ahmed T.; Glavey, Siobhan V.; Bezman, Natalie A.; Jhatakia, Amy; Guerriero, Jennifer L.; Manier, Salomon; Moschetta, Michele; Mishima, Yuji; Roccaro, Aldo; Detappe, Alexandre; Liu, Chia-Jen; Sacco, Antonio; Huynh, Daisy; Tai, Yu-Tzu; Robbins, Michael D.; Azzi, Jamil; Ghobrial, Irene M. 分享 收藏
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The anti-SLAMF7 antibody elotuzumab mediates NK cell activation through both CD16-dependent and -independent mechanisms Pazina, Tatiana; James, Ashley M.; MacFarlane, Alexander W.; Bezman, Natalie A.; Henning, Karla A.; Bee, Christine; Graziano, Robert F.; Robbins, Michael D.; Cohen, Adam D.; Campbell, Kerry S. 分享 收藏
PD-1 blockade enhances elotuzumab efficacy in mouse tumor models Bezman, Natalie A.; Jhatakia, Amy; Kearney, Alper Y.; Brender, Ty; Maurer, Mark; Henning, Karla; Jenkins, Misty R.; Rogers, Amy J.; Neeson, Paul J.; Korman, Alan J.; Robbins, Michael D.; Graziano, Robert F. 分享 收藏
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Copy Number Variation Plays an Important Role in Clinical Epilepsy Olson, Heather; Shen, Yiping; Avallone, Jennifer; Sheidley, Beth R.; Pinsky, Rebecca; Bergin, Ann M.; Berry, Gerard T.; Duffy, Frank H.; Eksioglu, Yaman; Harris, David J.; Hisama, Fuki M.; Ho, Eugenia; Irons, Mira; Jacobsen, Christina M.; James, Philip; Kothare, Sanjeev; Khwaja, Omar; Lipton, Jonathan; Loddenkemper, Tobias; Markowitz, Jennifer; Maski, Kiran; Megerian, J. Thomas; Neilan, Edward; Raffalli, Peter C.; Robbins, Michael; Roberts, Amy; Roe, Eugene; Rollins, Caitlin; Sahin, Mustafa; Sarco, Dean; Schonwald, Alison; Smith, Sharon E.; Soul, Janet; Stoler, Joan M.; Takeoka, Masanori; Tan, Wen-Han; Torres, Alcy R.; Tsai, Peter; Urion, David K.; Weissman, Laura; Wolff, Robert; Wu, Bai-Lin; Miller, David T.; Poduri, Annapurna 分享 收藏
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Discovery of PF-04449913, a Potent and Orally Bioavailable Inhibitor of Smoothened Munchhof, Michael J.; Li, Qifang; Shavnya, Andrei; Borzillo, Gary V.; Boyden, Tracey L.; Jones, Christopher S.; LaGreca, Susan D.; Martinez-Alsina, Luis; Patel, Nandini; Pelletier, Kathleen; Reiter, Larry A.; Robbins, Michael D.; Tkalcevic, George T. 分享 收藏
PF-04449913, a small molecule inhibitor of Hedgehog signaling, is effective in inhibiting tumor growth in preclinical models Jackson-Fisher, Amy J.; McMahon, Melissa J.; Lam, Justine; Li, Chunze; Engstrom, Lars D.; Tsaparikos, Konstantinos; Shieldsi, David J.; Fang, Douglas D.; Lira, Maruja E.; Zhu, Zhou; Robbins, Michael D.; Schwab, Richard; Munchhof, Michael J.; VanArsdale, Todd 分享 收藏
Clinical Genetic Testing for Patients With Autism Spectrum Disorders Shen, Yiping; Dies, Kira A.; Holm, Ingrid A.; Bridgemohan, Carolyn; Sobeih, Magdi M.; Caronna, Elizabeth B.; Miller, Karen J.; Frazier, Jean A.; Silverstein, Iris; Picker, Jonathan; Weissman, Laura; Raffalli, Peter; Jeste, Shafali; Demmer, Laurie A.; Peters, Heather K.; Brewster, Stephanie J.; Kowalczyk, Sara J.; Rosen-Sheidley, Beth; McGowan, Caroline; Duda, Andrew W., III; Lincoln, Sharyn A.; Lowe, Kathryn R.; Schonwald, Alison; Robbins, Michael; Hisama, Fuki; Wolff, Robert; Becker, Ronald; Nasir, Ramzi; Urion, David K.; Milunsky, Jeff M.; Rappaport, Leonard; Gusella, James F.; Walsh, Christopher A.; Wu, Bai-Lin; Miller, David T. 分享 收藏
Pharmacologic inhibition of site 1 protease activity inhibits sterol regulatory element-binding protein processing and reduces lipogenic enzyme gene expression and lipid synthesis in cultured cells and experimental animals Hawkins, Julie L.; Robbins, Michael D.; Warren, Laurie C.; Xia, Donghui; Petras, Stephen F.; Valentine, James J.; Varghese, Alison H.; Wang, Ing-Kae; Subashi, Timothy A.; Shelly, Lorraine D.; Hay, Bruce A.; Landschulz, Katherine T.; Geoghegan, Kieran F.; Harwood, H. James, Jr. 分享 收藏
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