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李健 封面图

李健 (Jian Li)

Joslin Diabetes Center

34H指数
211论文数
3.3K被引数
收录论文 50
发表时间
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Loss of function of ALDH3B2 transdifferentiates human pancreatic duct cells into β-like cellsALDH3B2功能丧失将人胰腺导管细胞转分化为β样细胞
errScience Translational Medicine
IF14.6
err2026-09-02
err0
PREAI
errJian Li; Kevin Bode; Yu-chi Lee; Noelle Morrow; Andy Ma; Mulin He; Siying Wei; Jessica da Silva Pereira; Taylor Stewart; Alexander Lee-Papastavros; Jennifer Hollister-Lock; Brooke A. Sullivan; Hui Pan; Jonathan M. Dreyfuss; Susan Bonner-Weir; Peng Yi
err分享
err收藏
Downregulation of SNORD20 promotes ferroptosis in corpus cavernosum smooth muscle cells from diabetic rats through inducing the mitochondrial dysfunctionSNORD20的下调通过诱导线粒体功能障碍，促进糖尿病大鼠海绵体平滑肌细胞的铁死亡。
errNeuropharmacology
IF4.6
err2025-12-15
err0
PREAI
errYiyu Qin; Wenjie Huang; Yang Zhou; Yuping Chen; Jian Li; Zhiyue Wu
err分享
err收藏
Arabinoxylan confers protection against bile acid-induced growth and metabolic impairments in Bifidobacterium longum subsp. longum阿拉伯木聚糖为长双歧杆菌长亚种提供针对胆汁酸诱导的生长和代谢损伤的保护。
errFood Bioscience
IF5.9
err2025-08-26
err0
PREAI
errYujing Sun; Zhongmin Yang; Xin Liao; Chaoxiang Chen; Daren Wu; Jian Li; Jingwen Liu; Zhengxiao Zhang
err分享
err收藏
ZmPOD5 positively regulates drought tolerance by modulating ROS productionZmPOD5通过调控ROS产生正向调节抗旱性。
errPlant Science
IF4.1
err2025-08-06
err0
PREAI
errRui Li; Jian Li; Minghao Sun; Yang Qin; Yunling Peng; Yiru Wang; Jun Zheng
err分享
err收藏
RNA-seq reveals Lysyl oxidase as a potential biomarker of glomerular function in diabetic nephropathy in ratsRNA-seq揭示赖氨酰氧化酶是糖尿病肾病大鼠肾小球功能的一个潜在生物标志物
errGENE
IF2.4
err2025-04-01
err0
PREAI
errLiu, Jiaxuan; Bai, Sufen; Wu, Chenxi; Tian, Chunyu; Fu, Qianru; Gao, Xiujuan; Zhang, Biwei; Li, Ji'an; La, Xiaojin
err分享
err收藏
Pickled radish alleviates the progression of colitis in mice by reducing inflammation and repairing intestinal barrier
errJOURNAL OF FUNCTIONAL FOODS
IF4
err2024-12-01
err0
errOAAI
errZhang, Ling-Yu; Ma, Liuyan; Luo, Lian-zhong; Li, Jian
err分享
err收藏
Beta cells deficient for Renalase counteract autoimmunity by shaping natural killer cell activity
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2024-06-04
err1
errOAAI
errBode, Kevin; Wei, Siying; Gruber, Isabella; Li, Jian; Kissler, Stephan; Yi, Peng
err分享
err收藏
Association between obesity and the prevalence of dyslipidemia in middle-aged and older people: an observational study
errSCIENTIFIC REPORTS
IF3.9
err2024-05-25
err7
errOAAI
errZheng, Chuanlei; Liu, Yanhong; Xu, Cong; Zeng, Shaobo; Wang, Qi; Guo, Yixing; Li, Jian; Li, Sisi; Dong, Minghua; Luo, Xiaoting; Wu, Qingfeng
err分享
err收藏
IL-37 ameliorates myocardial fibrosis by regulating mtDNA-enriched vesicle release in diabetic cardiomyopathy mice
errJOURNAL OF TRANSLATIONAL MEDICINE
IF7.5
err2024-05-24
err1
errOAAI
errHuang, Qingyu; Chen, Tongqing; Li, Jian; Wang, Yiming; Shi, Huairui; Yu, Yifei; Ji, Qingwei; Shen, Xiaoyan; Sun, Tao; Shi, Haiming; Luo, Xinping; Jin, Bo; You, Yan; Wu, Bangwei
err分享
err收藏
Targeted characterization and guided isolation of chemical components in Scrophulariae Radix based on LC-MS
errJOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
IF3.1
err2023-10-01
err0
PREAI
errXu, Siyi; Tan, Yajie; Xia, Yun; Tang, Haojun; Li, Jian; Tan, Ninghua
err分享
err收藏
Dedifferentiated fat cells: current applications and future directions in regenerative medicine
errSTEM CELL RESEARCH & THERAPY
IF7.3
err2023-08-21
err11
errOAAI
errLiang, Zhuokai; He, Yufei; Tang, Haojing; Li, Jian; Cai, Junrong; Liao, Yunjun
err分享
err收藏
Nucleophilic Radicals as Hydrogen Atom Abstractors in C(sp3)-H Functionalization Reactions
errCHINESE JOURNAL OF CHEMISTRY
IF5.5
err2023-01-09
err7
PREAI
errLi, Tao; Li, Jian; Huo, Haohua
err分享
err收藏
Mutations in the TBX15-ADAMTS2 pathway associate with a novel soft palate dysplasia
errHUMAN MUTATION
IF3.7
err2022-09-30
err1
errOAAI
errZhang, Yuying; Li, Jian; Ji, Yaoting; Cheng, Yibin; Fu, Xiazhou
err分享
err收藏
A rapid quantitative method by liquid chromatography-tandem mass spectrometry for the measurement of anthocyanins and their metabolic characteristics in Sprague-Dawley rats
errEUROPEAN FOOD RESEARCH AND TECHNOLOGY
IF3.2
err2022-05-14
err3
PREAI
errLian, Yueru; Niu, Liyun; Meng, Zhiyun; Zhu, Xiaoxia; Gu, Ruolan; Wu, Zhuona; Li, Jian; Han, Peng; Liu, Taoyun; Gan, Hui; Dou, Guifang
err分享
err收藏
BRD4 Inhibition Attenuates Inflammatory Pain by Ameliorating NLRP3 Inflammasome-Induced Pyroptosis
errFRONTIERS IN IMMUNOLOGY
IF5.9
err2022-01-26
err26
errOAAI
errHua, Tong; Wang, Haowei; Fan, Xiaoyi; An, Ni; Li, Jian; Song, Honghao; Kong, Erliang; Li, Yongchang; Yuan, Hongbin
err分享
err收藏
Blastocyst Transfer: A Risk Factor for Gestational Diabetes Mellitus in Women Undergoing In Vitro Fertilization
errJOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
IF5.1
err2021-08-20
err10
errOAAI
errChen, Huijun; Li, Jian; Cai, Sufen; Tang, Sha; Zeng, Suimin; Chu, Chang; Hocher, Carl-Friedrich; Rosing, Benjamin; Kramer, Bernhard K.; Hu, Liang; Lin, Ge; Gong, Fei; Hocher, Berthold
err分享
err收藏
Cardioprotective mechanism of SGLT2 inhibitor against myocardial infarction is through reduction of autosisSGLT2抑制剂对心肌梗死的心脏保护机制是通过减少自体
errPROTEIN & CELL
IF12.8
err2021-01-08
err103
errOAAI
errJiang, Kai; Xu, Yue; Wang, Dandan; Chen, Feng; Tu, Zizhuo; Qian, Jie; Xu, Sheng; Xu, Yixiang; Hwa, John; Li, Jian; Shang, Hongcai; Xiang, Yaozu
err分享
err收藏
Integrated HPLC fingerprinting and multivariate analysis differentiates between wild and cultivated Hedyotis diffusa Willd
errINDUSTRIAL CROPS AND PRODUCTS
IF6.2
err2020-06-01
err12
PREAI
errWang, Xin; Ma, Chuanjiang; Yang, Peimin; Wei, Yongli; Jia, Jing; Cao, Guangshang; Li, Jian; Xin, Yizhou
err分享
err收藏
Neuroprotective effect of diosgenin in a mouse model of diabetic peripheral neuropathy involves the Nrf2/HO-1 pathway薯蓣皂苷元在糖尿病周围神经病变小鼠模型中的神经保护作用涉及Nrf2/HO-1通路
errBMC COMPLEMENTARY MEDICINE AND THERAPIES
IF3.4
err2020-04-26
err37
errOAAI
errLeng, Jinhong; Li, Xiaohua; Tian, He; Liu, Chang; Guo, Yining; Zhang, Su; Chu, Yang; Li, Jian; Wang, Ying; Zhang, Ling
err分享
err收藏
ALDH7A1 inhibits the intracellular transport pathways during hypoxia and starvation to promote cellular energy homeostasis
errNATURE COMMUNICATIONS
IF15.7
err2019-09-06
err14
errOAAI
errYang, Jia-Shu; Hsu, Jia-Wei; Park, Seung-Yeol; Lee, Stella Y.; Li, Jian; Bai, Ming; Alves, Claudia; Tseng, William; Michelet, Xavier; Ho, I-Cheng; Hsu, Victor W.
err分享
err收藏

研究方向

食品营养、天然活性物质、食品生物技术等生物与医药老菜脯特征酚类物质形成分子机制及调控海洋食源性护肤活性物质绿色开发与高效利用棘胸蛙的种质资源的保护与高值化利用福建省高校产学合作重点项目抗高原缺氧功能性产品研制及产业化示范西藏自治区科技计划技术创新引导计划项目肉苁蓉功能食品加工关键技术研发及应用示范福建省科技厅对外合作项目高端滋补营养品产业化关键技术研究 厦门市科技计划项目棘胸蛙粉片剂的营养解析及生产工艺研究 泉州市科技重点项目海洋食源性危害物快速检测技术平台建设 福建省财政厅项目茶色素的提取制备及产业化关键技术开发 横向项目海洋益生功能生物制剂关键技术研究及产业化 横向项目依托科技小院的农业硕士培养模式构建与实践福建省本科高校教育教学研究项目（重大项目）柑橘皮生物活性化合物鉴定降尿酸活性评价抗氧化多肽制备分子模拟余甘子抗菌酚类衍生物构效关系研究余甘子脱苦及生物活性膳食与肠道健康, 239-251lipid compositionQuasipaa spinosa oilRana catesbeiana oillipid accumulationCaenorhabditis elegans膳食木脂素雌激素效应安全性评价木脂素吸收代谢膳食磷脂缓解饮食诱导小鼠肥胖金线莲黄酮类化合物鉴定及其对代谢综合征相关酶的体外抑制, 5916-5926微生物源抑菌物质人乳脂质中链和长链甘油三酯健康影响天然植物化学物质泡菜萝卜纯化与表征下一代植物纳米药物细胞衍生纳米囊泡用于天然产物递送环脂肽提取与表征抗真菌活性抗氧化活性腌萝卜酚类物质的黄嘌呤氧化酶抑制活性及分子模拟研究螺旋藻α-葡聚糖的分离、纯化、表征及免疫调节活性分析抑制α-葡萄糖苷酶活性多肽抑制血管紧张素转化酶活性的棘胸蛙多肽及其制备方法和应用没食子酸在植物病害防治中的应用柯里拉京提取方法与应用从余甘子中提取的1-O-没食子酸酰基-β-D-葡萄糖苷在植物病害防治中的应用棘胸蛙冻干粉的全流程生产工艺螺旋藻丁香酸制备其他代表性成果农业农村部福建德化棘胸蛙科技小院，项目负责人，2022年
合作学者
合作期刊
R
Robert R. Recker
H 指数: 108 · 论文数: 634
K
Khalid Iqbal
H 指数: 108 · 论文数: 522
S
Susan Bonner‐Weir
H 指数: 106 · 论文数: 382
王
王颖 (Ying Wang)
H 指数: 105 · 论文数: 1.5K
Z
Zhenhua Wu
H 指数: 89 · 论文数: 1.9K
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