Andrew R. Marks - Publications, H-index & Citations

Andrew R. Marks

columbia university irving medical center

98H指数

352论文数

3.5W被引数

收录论文 149

发表时间

Structural identification of the RY12 domain of RyR1 as an ADP sensor and the target of the malignant hyperthermia therapeutic dantrolene ryanodine受体1的RY12结构域作为ADP传感器的结构鉴定及其作为恶性高热症治疗药物丹曲洛林的靶点

Nature Communications

IF15.7

2026-09-04

OAAI

Kookjoo Kim; Huan Li; Qi Yuan; Zephan Melville; Ran Zalk; Amédée des Georges; Joachim Frank; Wayne A. Hendrickson; Andrew R. Marks; Oliver B. Clarke

Structural basis for rosuvastatin-induced activation of skeletal muscle ryanodine receptor 1 罗苏伐他汀诱导骨骼肌ryanodine受体1活化的结构基础

Nature Communications

IF15.7

2026-09-03

OAAI

Gunnar Weninger; Steven Reiken; Qi Yuan; Marco C. Miotto; Alexander Chang; Yang Liu; Anetta Wronska; Haikel Dridi; Andrew R. Marks

Structural basis for simvastatin-induced skeletal muscle weakness associated with type 1 ryanodine receptor T4709M mutation simvastatin诱导的与型1 Ryanodine受体T4709M突变相关的骨骼肌无力结构基础

Journal of Clinical Investigation

IF13.6

2025-12-15

PREAI

Weninger, Gunnar; Dridi, Haikel; Reiken, Steven; Yuan, Qi; Zhao, Nan; Groom, Linda; Leigh, Jennifer; Liu, Yang; Tchagou, Carl; Kang, Jiayi; Chang, Alexander; Luna-Figueroa, Estefania; Miotto, Marco C.; Wronska, Anetta; Dirksen, Robert T.; Marks, Andrew R.

Feeding the cosmos: tackling personalized space nutrition and the leaky gut challenge 喂养宇宙：应对个性化太空营养和肠道渗漏挑战

npj Microgravity

IF4.1

2025-07-18

OAAI

B. Barbero Barcenilla; R. Rivero; A. Lynch; W. Cromer; J. Gong; B. Harandi; M. Stegmann; H. Le; D. Lundine; M. Chung; J. Puig; K. Mikhailova; H. Coker; A. Marks; R. Gilbert; R. Scott; R. Barker; P. Glowe; Eliah G. Overbey; C. E. Mason

Structural basis for ryanodine receptor type 2 leak in heart failure and arrhythmogenic disorders

NATURE COMMUNICATIONS

IF15.7

2024-09-15

OAAI

Miotto, Marco C.; Reiken, Steven; Wronska, Anetta; Yuan, Qi; Dridi, Haikel; Liu, Yang; Weninger, Gunnar; Tchagou, Carl; Marks, Andrew R.

Structural insights into the regulation of RyR1 by S100A1

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2024-06-25

OAAI

Weninger, Gunnar; Miotto, Marco C.; Tchagou, Carl; Reiken, Steven; Dridi, Haikel; Brandenburg, Soeren; Riedemann, Gabriel C.; Yuan, Qi; Liu, Yang; Chang, Alexander; Wronska, Anetta; Lehnart, Stephan E.; Marks, Andrew R.

Rycal S48168 (ARM210) for RYR1-related myopathies: a phase one, open-label, dose-escalation trial

ECLINICALMEDICINE

IF10

2024-02-01

OAAI

Todd, Joshua J.; Lawal, Tokunbor A.; Chrismer, Irene C.; Kokkinis, Angela; Grunseich, Christopher; Jain, Minal S.; Waite, Melissa R.; Biancavilla, Victoria; Pocock, Shavonne; Brooks, Kia; Mendoza, Christopher J.; Norato, Gina; Cheung, Ken; Riekhof, Willa; Varma, Pooja; Colina-Prisco, Claudia; Emile-Backer, Magalie; Meilleur, Katherine G.; Marks, Andrew R.; Webb, Yael; Marcantonio, Eugene E.; Foley, A. Reghan; Boennemann, Carsten G.; Mohassel, Payam

Aberrant mitochondrial dynamics contributes to diaphragmatic weakness induced by mechanical ventilation

PNAS NEXUS

IF3.8

2023-11-07

OAAI

Dridi, Haikel; Yehya, Marc; Barsotti, Robert; Liu, Yang; Reiken, Steven; Azria, Lan; Yuan, Qi; Bahlouli, Laith; Soni, Rajesh Kumar; Marks, Andrew R.; Lacampagne, Alain; Matecki, Stefan

Personalized medicine in the dish to prevent calcium leak associated with short-coupled polymorphic ventricular tachycardia in patient-derived cardiomyocytes

STEM CELL RESEARCH & THERAPY

IF7.3

2023-09-23

OAAI

Sleiman, Yvonne; Reiken, Steven; Charrabi, Azzouz; Jaffre, Fabrice; Sittenfeld, Leah R.; Pasquie, Jean-Luc; Colombani, Sarah; Lerman, Bruce B.; Chen, Shuibing; Marks, Andrew R.; Cheung, Jim W.; Evans, Todd; Lacampagne, Alain; Meli, Albano C.

Defective cerebellar ryanodine receptor type 1 and endoplasmic reticulum calcium 'leak' in tremor pathophysiology

ACTA NEUROPATHOLOGICA

IF9.3

2023-06-19

OAAI

Martuscello, Regina T. T.; Chen, Meng-Ling; Reiken, Steven; Sittenfeld, Leah R. R.; Ruff, David S. S.; Ni, Chun-Lun; Lin, Chih-Chun; Pan, Ming-Kai; Louis, Elan D. D.; Marks, Andrew R. R.; Kuo, Sheng-Han; Faust, Phyllis L. L.

T cells deficient in inositol 1,4,5-trisphosphate receptor are resistant to apoptosis

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-29

257

OAAI

Jayaraman, T; Marks, AR

Targeting ryanodine receptors to treat human diseases

JOURNAL OF CLINICAL INVESTIGATION

IF13.6

2023-01-17

OAAI

Marks, Andrew R.

Modeling and drug screening of inherited short-coupled polymorphic ventricular tachycardia using patient derived tissue

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

IF4.7

2022-12-01

PREAI

Sleiman, Yvonne; Reiken, Steven; Charrabi, Azzouz; Jaffre, Fabrice; Sittenfeld, Leah R.; Pasquie, Jean-Luc; Lerman, Bruce B.; Chen, Shuibing; Marks, Andrew R.; Cheung, Jim W.; Evans, Todd; Lacampagne, Alain; Meli, Albano

Characterization of N-terminal RYR2 variants outside CPVT1 hotspot regions using patient iPSCs reveal pathogenesis and therapeutic potential

STEM CELL REPORTS

IF5.1

2022-09-01

OAAI

Stutzman, Marissa J.; Kim, C. S. John; J. Tester, David; Hamrick, Samantha K.; Dotzler, Steven M.; R. Giudessi, John; Miotto, Marco C.; Gc, Jeevan B.; Frank, Joachim; Marks, Andrew R.; Ackerman, Michael J.

Catching the next wave of recombinant RyR2 cryo-EM structures. Commentary on Molecular basis for gating of cardiac ryanodine receptor explains the mechanisms for gain- and loss-of function mutations

CELL CALCIUM

IF4

2022-07-01

PREAI

Miotto, Marco C.; Marks, Andrew R.

Alzheimer's-like signaling in brains of COVID-19 patients

ALZHEIMERS & DEMENTIA

IF11.1

2022-02-03

111

OAAI

Reiken, Steve; Sittenfeld, Leah; Dridi, Haikel; Liu, Yang; Liu, Xiaoping; Marks, Andrew R.

Acute RyR1 Ca2+ leak enhances NADH-linked mitochondrial respiratory capacity

NATURE COMMUNICATIONS

IF15.7

2021-12-10

OAAI

Zanou, Nadege; Dridi, Haikel; Reiken, Steven; de Lima, Tanes Imamura; Donnelly, Chris; De Marchi, Umberto; Ferrini, Manuele; Vidal, Jeremy; Sittenfeld, Leah; Feige, Jerome N.; Garcia-Roves, Pablo M.; Lopez-Mejia, Isabel C.; Marks, Andrew R.; Auwerx, Johan; Kayser, Bengt; Place, Nicolas

ACTA NEUROPATHOLOGICA COMMUNICATIONS

IF5.7

2021-11-22

OAAI

Yuan, Qi; Dridi, Haikel; Clarke, Oliver B.; Reiken, Steven; Melville, Zephan; Wronska, Anetta; Kushnir, Alexander; Zalk, Ran; Sittenfeld, Leah; Marks, Andrew R.

Attenuating persistent sodium current- induced atrial myopathy and fibrillation by preventing mitochondrial oxidative stress

JCI INSIGHT

IF6.1

2021-10-28

OAAI

Avula, Uma Mahesh R.; Dridi, Haikel; Chen, Bi-Xing; Yuan, Qi; Katchman, Alexander N.; Reiken, Steven R.; Desai, Amar D.; Parsons, Samantha; Baksh, Haajra; Ma, Elaine; Dasrat, Parmanand; Ji, Ruiping; Lin, Yejun; Sison, Christine; Lederer, W. Jonathan; Joca, Humberto C.; Ward, Christopher W.; Greiser, Maura; Marks, Andrew R.; Marx, Steven O.; Wan, Elaine Y.

Ryanodine receptor remodeling in cardiomyopathy and muscular dystrophy caused by lamin A/C gene mutation

HUMAN MOLECULAR GENETICS

IF3.2

2021-01-04

OAAI

Dridi, Haikel; Wu, Wei; Reiken, Steven R.; Ofer, Rachel M.; Liu, Yang; Yuan, Qi; Sittenfeld, Leah; Kushner, Jared; Muchir, Antoine; Worman, Howard J.; Marks, Andrew R.

研究方向