未登录 Loss of PTEN as an Independent Poor Prognosis Indicator in Lung Adenocarcinoma, but Not in Squamous Cell Carcinoma, Is Associated with an Immunosuppressive Tumor Microenvironment and Distinct Co-Mutational Profiles PTEN缺失作为肺腺癌的独立不良预后指标，但在鳞状细胞癌中并非如此，这与免疫抑制性肿瘤微环境和独特的共突变谱相关 Houry, Maeva; Silva, Shannon J.; Artola, Maider; Behrens, Carmen; Politi, Katerina; Wistuba, Ignacio; Montuenga, Luis; Exposito, Francisco; Calvo, Alfonso 分享 收藏
Enhancing NSCLC recurrence prediction with PET/CT habitat imaging, ctDNA, and integrative radiogenomics-blood insights 通过PET/CT栖息地成像，ctDNA和综合放射基因组学增强NSCLC复发预测-血液见解 Sujit, Sheeba J.; Aminu, Muhammad; Karpinets, Tatiana V.; Chen, Pingjun; Saad, Maliazurina B.; Salehjahromi, Morteza; Boom, John D.; Qayati, Mohamed; George, James M.; Allen, Haley; Antonoff, Mara B.; Hong, Lingzhi; Hu, Xin; Heeke, Simon; Tran, Hai T.; Le, Xiuning; Elamin, Yasir Y.; Altan, Mehmet; Vokes, Natalie I.; Sheshadri, Ajay; Lin, Julie; Zhang, Jianhua; Lu, Yang; Behrens, Carmen; Godoy, Myrna C. B.; Wu, Carol C.; Chang, Joe Y.; Chung, Caroline; Jaffray, David A.; Wistuba, Ignacio I.; Lee, J. Jack; Vaporciyan, Ara A.; Gibbons, Don L.; Heymach, John; Zhang, Jianjun; Cascone, Tina; Wu, Jia 分享 收藏
Synthetic PET from CT improves diagnosis and prognosis for lung cancer: Proof of concept CT合成PET改善肺癌的诊断和预后: 概念验证 Salehjahromi, Morteza; Karpinets, Tatiana, V; Sujit, Sheeba J.; Qayati, Mohamed; Chen, Pingjun; Aminu, Muhammad; Saad, Maliazurina B.; Bandyopadhyay, Rukhmini; Hong, Lingzhi; Sheshadri, Ajay; Lin, Julie; Antonoff, Mara B.; Sepesi, Boris; Ostrin, Edwin J.; Toumazis, Iakovos; Huang, Peng; Cheng, Chao; Cascone, Tina; Vokes, Natalie I.; Behrens, Carmen; Siewerdsen, Jeffrey H.; Hazle, John D.; Chang, Joe Y.; Zhang, Jianhua; Lu, Yang; Godoy, Myrna C. B.; Chung, Caroline; Jaffray, David; Wistuba, Ignacio; Lee, J. Jack; Vaporciyan, Ara A.; Gibbons, Don L.; Gladish, Gregory; Heymach, John, V; Wu, Carol C.; Zhang, Jianjun; Wu, Jia 分享 收藏
Deep LearningeBased H-Score Quantification of Immunohistochemistry-Stained Images 基于深度学习的免疫组化染色图像的H评分量化 Wen, Zhuoyu; Luo, Danni; Wang, Shidan; Rong, Ruichen; Evers, Bret M.; Jia, Liwei; Fang, Yisheng; Daoud, Elena, V; Yang, Shengjie; Gu, Zifan; Arnerc, Emily N.; Lewis, Cheryl M.; Soto, Luisa M. Solis; Fujimoto, Junya; Behrens, Carmen; Wistuba, Ignacio I.; Yang, Donghan M.; Brekken, Rolf A.; O'Donnell, Kathryn A.; Xie, Yang; Xiao, Guanghua 分享 收藏
Immune cellular patterns of distribution affect outcomes of patients with non-small cell lung cancer Parra, Edwin Roger; Zhang, Jiexin; Jiang, Mei; Tamegnon, Auriole; Pandurengan, Renganayaki Krishna; Behrens, Carmen; Solis, Luisa; Haymaker, Cara; Heymach, John Victor; Moran, Cesar; Lee, Jack J.; Gibbons, Don; Wistuba, Ignacio Ivan 分享 收藏
A circulating microRNA panel predicts recurrence and survival in early-stage lung adenocarcinoma Tai, Mei-Chee; Bantis, Leonidas E.; Parhy, Gargy; Kato, Taketo; Tanaka, Ichidai; Chow, Chi-Wan; Fujimoto, Junya; Behrens, Carmen; Hase, Tetsunari; Kawaguchi, Koji; Fahrmann, Johannes F.; Ostrin, Edwin; Yokoi, Kohei; Chen-Yoshikawa, Toyofumi F.; Hasegawa, Yoshinori; Hanash, Samir M.; Wistuba, Ignacio I.; Taguchi, Ayumu 分享 收藏
Spatial profiling of immune biomarkers in resected treatment-naive early stage lung adenocarcinoma Hernandez, Sharia D.; Lu, Wei; Serrano, Alejandra G.; Arrechedera, Claudio J.; Sanchez-Espiridion, Beatriz; Ozirmak, Nejla; Molina, Max; Kostousov, Larisa; Barnes, Sean; Khan, Khaja; Tang, Ximing; Fujimoto, Junya; Parra, Edwin R.; Raso, Gabriela; Schmidt, Stephanie T.; Behrens, Carmen; Heymach, John; Zhang, Jianjun; Chen, Ken; Sepesi, Boris; Cascone, Tina; Gibbons, Don; Wistuba, Ignacio I.; Haymaker, Cara; Solis, Luisa M. 分享 收藏
Features of tumor-microenvironment images predict targeted therapy survival benefit in patients with EGFR-mutant lung cancer Wang, Shidan; Rong, Ruichen; Yang, Donghan M.; Fujimoto, Junya; Bishop, Justin A.; Yan, Shirley; Cai, Ling; Behrens, Carmen; Berry, Lynne D.; Wilhelm, Clare; Aisner, Dara; Sholl, Lynette; Johnson, Bruce E.; Kwiatkowski, David J.; Wistuba, Ignacio I.; Bunn, Paul A.; Minna, John; Xiao, Guanghu; Kris, Mark G.; Xie, Yang 分享 收藏
Analysis of Immune Intratumor Heterogeneity Highlights Immunoregulatory and Coinhibitory Lymphocytes as Hallmarks of Recurrence in Stage I Non-Small Cell Lung Cancer Francisco-Cruz, Alejandro; Rocha, Pedro; Reuben, Alexandre; Krishnan, Santhoshi N.; Das, Priyam; Chen, Runzhe; Quek, Kelly; Li, Jun; Parra, Edwin R.; Solis, Luisa M.; Barua, Souptik; Jiang, Mei; Lazcano, Rossana; Chow, Chi-Wan; Behrens, Carmen; Gumb, Curtis; Little, Latasha; Fukuoka, Junya; Kalhor, Neda; Weissferdt, Annikka; Kadara, Humam; Heymach, John V.; Swisher, Stephen; Sepesi, Boris; Rao, Arvind; Moran, Cesar; Zhang, Jianhua; Lee, J. Jack; Fujimoto, Junya; Futreal, P. Andrew; Wistuba, Ignacio I.; Peterson, Christine B.; Zhang, Jianjun 分享 收藏
Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer (vol 13, 4327, 2022) Bartolacci, Caterina; Andreani, Cristina; Vale, Goncalo; Berto, Stefano; Melegari, Margherita; Crouch, Anna Colleen; Baluya, Dodge L.; Kemble, George; Hodges, Kurt; Starrett, Jacqueline; Politi, Katerina; Starnes, Sandra L.; Lorenzini, Daniele; Raso, Maria Gabriela; Solis Soto, Luisa M.; Behrens, Carmen; Kadara, Humam; Gao, Boning; Wistuba, Ignacio I.; Minna, John D.; McDonald, Jeffrey G.; Scaglioni, Pier Paolo 分享 收藏
Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer 靶向从头脂肪生成和Lands循环在KRAS突变型肺癌中诱导铁死亡 Bartolacci, Caterina; Andreani, Cristina; Vale, Goncalo; Berto, Stefano; Melegari, Margherita; Crouch, Anna Colleen; Baluya, Dodge L.; Kemble, George; Hodges, Kurt; Starrett, Jacqueline; Politi, Katerina; Starnes, Sandra L.; Lorenzini, Daniele; Raso, Maria Gabriela; Soto, Luisa M. Solis; Behrens, Carmen; Kadara, Humam; Gao, Boning; Wistuba, Ignacio I.; Minna, John D.; McDonald, Jeffrey G.; Scaglioni, Pier Paolo 分享 收藏
Shared Nearest Neighbors Approach and Interactive Browser for Network Analysis of a Comprehensive Non-Small-Cell Lung Cancer Data Set Schmidt, Stephanie T.; Akhave, Neal; Knightly, Ryan E.; Reuben, Alexandre; Vokes, Natalie; Zhang, Jianhua; Li, Jun; Fujimoto, Junya; Byers, Lauren A.; Sanchez-Espiridion, Beatriz; Diao, Lixia; Wang, Jing; Federico, Lorenzo; Forget, Marie-Andree; McGrail, Daniel J.; Weissferdt, Annikka; Lin, Shiaw-Yih; Lee, Younghee; Suzuki, Erika; Kovacs, Jeffrey J.; Behrens, Carmen; Wistuba, Ignacio I.; Futreal, Andrew; Vaporciyan, Ara; Sepesi, Boris; Heymach, John V.; Bernatchez, Chantale; Haymaker, Cara; Cascone, Tina; Zhang, Jianjun; Bristow, Christopher A.; Heffernan, Timothy P.; Negrao, Marcelo V.; Gibbons, Don L. 分享 收藏
Immunogenomic intertumor heterogeneity across primary and metastatic sites in a patient with lung adenocarcinoma Chen, Runzhe; Li, Jun; Fujimoto, Junya; Hong, Lingzhi; Hu, Xin; Quek, Kelly; Tang, Ming; Mitra, Akash; Behrens, Carmen; Chow, Chi-Wan; Jiang, Peixin; Little, Latasha D.; Gumbs, Curtis; Song, Xingzhi; Zhang, Jianhua; Tan, Dongfeng; Heymach, John, V; Wistuba, Ignacio; Futreal, P. Andrew; Gibbons, Don L.; Byers, Lauren A.; Zhang, Jianjun; Reuben, Alexandre 分享 收藏
MTAP deficiency creates an exploitable target for antifolate therapy in 9p21-loss cancers Alhalabi, Omar; Chen, Jianfeng; Zhang, Yuxue; Lu, Yang; Wang, Qi; Ramachandran, Sumankalai; Tidwell, Rebecca Slack; Han, Guangchun; Yan, Xinmiao; Meng, Jieru; Wang, Ruiping; Hoang, Anh G.; Wang, Wei-Lien; Song, Jian; Lopez, Lidia; Andreev-Drakhlin, Alex; Siefker-Radtke, Arlene; Zhang, Xinqiao; Benedict, William F.; Shah, Amishi Y.; Wang, Jennifer; Msaouel, Pavlos; Zhang, Miao; Guo, Charles C.; Czerniak, Bogdan; Behrens, Carmen; Soto, Luisa; Papadimitrakopoulou, Vassiliki; Lewis, Jeff; Rinsurongkawong, Waree; Rinsurongkawong, Vadeerat; Lee, Jack; Roth, Jack; Swisher, Stephen; Wistuba, Ignacio; Heymach, John; Wang, Jing; Campbell, Matthew T.; Efstathiou, Eleni; Titus, Mark; Logothetis, Christopher J.; Ho, Thai H.; Zhang, Jianjun; Wang, Linghua; Gao, Jianjun 分享 收藏
AXL targeting restores PD-1 blockade sensitivity of STK11/LKB1 mutant NSCLC through expansion of TCF1+ CD8 T cells Li, Huiyu; Liu, Zhida; Liu, Longchao; Zhang, Hongyi; Han, Chuanhui; Girard, Luc; Park, Hyunsil; Zhang, Anli; Dong, Chunbo; Ye, Jianfeng; Rayford, Austin; Peyton, Michael; Li, Xiaoguang; Avila, Kimberley; Cao, Xuezhi; Hu, Shuiqing; Alam, Md Maksudul; Akbay, Esra A.; Solis, Luisa M.; Behrens, Carmen; Hernandez-Ruiz, Sharia; Lu, Wei; Wistuba, Ignacio; Heymach, John, V; Chisamore, Michael; Micklem, David; Gabra, Hani; Gausdal, Gro; Lorens, James B.; Li, Bo; Fu, Yang-Xin; Minna, John D.; Brekken, Rolf A. 分享 收藏
The histologic phenotype of lung cancers is associated with transcriptomic features rather than genomic characteristics Tang, Ming; Abbas, Hussein A.; Negrao, Marcelo V.; Ramineni, Maheshwari; Hu, Xin; Hubert, Shawna Marie; Fujimoto, Junya; Reuben, Alexandre; Varghese, Susan; Zhang, Jianhua; Li, Jun; Chow, Chi-Wan; Mao, Xizeng; Song, Xingzhi; Lee, Won-Chul; Wu, Jia; Little, Latasha; Gumbs, Curtis; Behrens, Carmen; Moran, Cesar; Weissferdt, Annikka; Lee, J. Jack; Sepesi, Boris; Swisher, Stephen; Cheng, Chao; Kurie, Jonathan; Gibbons, Don; Heymach, John V.; Wistuba, Ignacio I.; Futreal, P. Andrew; Kalhor, Neda; Zhang, Jianjun 分享 收藏
A shared nearest neighbors approach for integrated, multi-platform networks and its application to the exploration of multiomics data from early-stage non-small cell lung cancers Schmidt, Stephanie T.; Akhave, Neal; Reuben, Alexandre; Cascone, Tina; Zhang, Jianhua; Li, Jun; Fujimoto, Junya; Byers, Lauren A.; Sanchez-Espiridion, Beatriz; Diao, Lixia; Wang, Jing; Federico, Lorenzo; Forget, Marie-Andree; McGrail, Daniel J.; Weissferdt, Annikka; Lin, Shiaw-Yih; Lee, Younghee; Vokes, Natalie; Behrens, Carmen; Wistuba, Ignacio I.; Futreal, Andrew; Vaporciyan, Ara; Sepesi, Boris; Heymach, John V.; Bernatchez, Chantale; Haymaker, Cara; Zhang, Jianjun; Bristow, Christopher A.; Heffernan, Timothy P.; Negrao, Marcelo V.; Gibbons, Don L. 分享 收藏
Distinct immune gene programs associated with host tumor immunity, neoadjuvant chemotherapy and chemoimmunotherapy in resectable NSCLC Rocha, P.; Zhang, J.; Laza-Briviesca, R.; Cruz-Bermudez, A.; Yoshimura, K.; Behrens, C.; Pataer, A.; Parra, E. R.; Haymaker, C.; Fujimoto, J.; Swisher, S. G.; Heymach, J. V.; Gibbons, D. L.; Lee, J. J.; Sepesi, B.; Cascone, T.; Solis, L. M.; Provencio, M.; Kadara, H.; Wistuba, I. I. 分享 收藏
Cold and heterogeneous T cell repertoire is associated with copy number aberrations and loss of immune genes in small-cell lung cancer Chen, Ming; Chen, Runzhe; Jin, Ying; Li, Jun; Hu, Xin; Zhang, Jiexin; Fujimoto, Junya; Hubert, Shawna M.; Gay, Carl M.; Zhu, Bo; Tian, Yanhua; McGranahan, Nicholas; Lee, Won-Chul; George, Julie; Hu, Xiao; Chen, Yamei; Wu, Meijuan; Behrens, Carmen; Chow, Chi-Wan; Pham, Hoa H. N.; Fukuoka, Junya; Wu, Jia; Parra, Edwin Roger; Little, Latasha D.; Gumbs, Curtis; Song, Xingzhi; Wu, Chang-Jiun; Diao, Lixia; Wang, Qi; Cardnell, Robert; Zhang, Jianhua; Wang, Jing; Le, Xiuning; Gibbons, Don L.; Heymach, John, V; Lee, J. Jack; William, William N., Jr.; Cheng, Chao; Glisson, Bonnie; Wistuba, Ignacio; Futreal, P. Andrew; Thomas, Roman K.; Reuben, Alexandre; Byers, Lauren A.; Zhang, Jianjun 分享 收藏
SRGN-Triggered Aggressive and Immunosuppressive Phenotype in a Subset of TTF-1-Negative Lung Adenocarcinomas Tanaka, Ichidai; Dayde, Delphine; Tai, Mei Chee; Mori, Haruki; Solis, Luisa M.; Tripathi, Satyendra C.; Fahrmann, Johannes F.; Unver, Nese; Parhy, Gargy; Jain, Rekha; Parra, Edwin R.; Murakami, Yoshiko; Aguilar-Bonavides, Clemente; Mino, Barbara; Celiktas, Muge; Dhillon, Dilsher; Casabar, Julian Phillip; Nakatochi, Masahiro; Stingo, Francesco; Baladandayuthapani, Veera; Wang, Hong; Katayama, Hiroyuki; Dennison, Jennifer B.; Lorenzi, Philip L.; Do, Kim-Anh; Fujimoto, Junya; Behrens, Carmen; Ostrin, Edwin J.; Rodriguez-Canales, Jaime; Hase, Tetsunari; Fukui, Takayuki; Kajino, Taisuke; Kato, Seiichi; Yatabe, Yasushi; Hosoda, Waki; Kawaguchi, Koji; Yokoi, Kohei; Chen-Yoshikawa, Toyofumi F.; Hasegawa, Yoshinori; Gazdar, Adi F.; Wistuba, Ignacio I.; Hanash, Samir; Taguchi, Ayumu 分享 收藏
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