未登录 Functional analysis across model systems implicates ribosomal proteins in growth and proliferation defects associated with hypoplastic left heart syndrome 跨模型系统的功能分析表明，核糖体蛋白与左心室发育不全综合征相关的生长和增殖缺陷有关。 Nielsen, Tanja; Kervadec, Anais; Theis, Jeanne L.; Missinato, Maria A.; Marchant, James; Romero, Michaela; Marchetti, Katya; Lamba, Aashna; Zeng, Xin-Xin, I; Berenguer, Marie; Walls, Stanley M.; Schroeder, Analyne; Birker, Katja; Duester, Greg; Grossfeld, Paul; Nelson, Timothy J.; Olson, Timothy M.; Ocorr, Karen; Bodmer, Rolf; Vogler, Georg; Colas, Alexandre R. 分享 收藏
The nutrient sensor CRTC and Sarcalumenin/thinman represent an alternate pathway in cardiac hypertrophy Dondi, Cristiana; Vogler, Georg; Gupta, Anjali; Walls, Stanley M.; Kervadec, Anais; Marchant, James; Romero, Michaela R.; Diop, Soda; Goode, Jason; Thomas, John B.; Colas, Alex R.; Bodmer, Rolf; Montminy, Marc; Ocorr, Karen 分享 收藏
From promoter motif to cardiac function: a single DPE motif affects transcription regulation and organ function in vivo 从启动子基序到心脏功能: 单个DPE基序影响体内转录调控和器官功能 Sloutskin, Anna; Itzhak, Dekel; Vogler, Georg; Pozeilov, Hadar; Ideses, Diana; Alter, Hadar; Adato, Orit; Shachar, Hadar; Doniger, Tirza; Shohat-Ophir, Galit; Frasch, Manfred; Bodmer, Rolf; Duttke, Sascha H.; Juven-Gershon, Tamar 分享 收藏
Multiplatform modeling of atrial fibrillation identifies phospholamban as a central regulator of cardiac rhythm Kervadec, Anais; Kezos, James; Ni, Haibo; Yu, Michael; Marchant, James; Spiering, Sean; Kannan, Suraj; Kwon, Chulan; Andersen, Peter; Bodmer, Rolf; Grandi, Eleonora; Ocorr, Karen; Colas, Alexandre R. 分享 收藏
Mitochondrial MICOS complex genes, implicated in hypoplastic left heart syndrome, maintain cardiac contractility and actomyosin integrity Birker, Katja; Ge, Shuchao; Kirkland, Natalie J.; Theis, Jeanne L.; Marchant, James; Fogarty, Zachary C.; Missinato, Maria A.; Kalvakuri, Sreehari; Grossfeld, Paul; Engler, Adam J.; Ocorr, Karen; Nelson, Timothy J.; Colas, Alexandre R.; Olson, Timothy M.; Vogler, Georg; Bodmer, Rolf 分享 收藏
Age-dependent Lamin changes induce cardiac dysfunction via dysregulation of cardiac transcriptional programs Kirkland, Natalie J.; Skalak, Scott H.; Whitehead, Alexander J.; Hocker, James D.; Beri, Pranjali; Vogler, Geo; Hum, Bill; Wang, Mingyi; Lakatta, Edward G.; Ren, Bing; Bodmer, Rolf; Engler, Adam J. 分享 收藏
Genetic architecture of natural variation of cardiac performance from flies to humans 从苍蝇到人类的心脏性能自然变异的遗传结构 Saha, Saswati; Spinelli, Lionel; Mondragon, Jaime A. Castro; Kervadec, Anais; Lynott, Michaela; Kremmer, Laurent; Roder, Laurence; Krifa, Sallouha; Torres, Magali; Brun, Christine; Vogler, Georg; Bodmer, Rolf; Colas, Alexandre R.; Ocorr, Karen; Perrin, Laurent 分享 收藏
分享 收藏
Conserved Role of the Large Conductance Calcium-Activated Potassium Channel, KCa1.1, in Sinus Node Function and Arrhythmia Risk Pineda, Santiago; Nikolova-Krstevski, Vesna; Leimena, Christiana; Atkinson, Andrew J.; Altekoester, Ann-Kristin; Cox, Charles D.; Jacoby, Arie; Huttner, Inken G.; Ju, Yue-Kun; Soka, Magdalena; Ohanian, Monique; Trivedi, Gunjan; Kalvakuri, Sreehari; Birker, Katja; Johnson, Renee; Molenaar, Peter; Kuchar, Dennis; Allen, David G.; van Helden, Dirk F.; Harvey, Richard P.; Hill, Adam P.; Bodmer, Rolf; Vogler, Georg; Dobrzynski, Halina; Ocorr, Karen; Fatkin, Diane 分享 收藏
Identification of MYOM2 as a candidate gene in hypertrophic cardiomyopathy and Tetralogy of Fallot, and its functional evaluation in the Drosophila heart Auxerre-Plantie, Emilie; Nielsen, Tanja; Grunert, Marcel; Olejniczak, Olga; Perrot, Andreas; Ozcelik, Cemil; Harries, Dennis; Matinmehr, Faramarz; Remedios, Cristobal Dos; Muhlfeld, Christian; Kraft, Theresia; Bodmer, Rolf; Vogler, Georg; Sperling, Silke R. 分享 收藏
Prolonged Exposure to Microgravity Reduces Cardiac Contractility and Initiates Remodeling in Drosophila Walls, Stanley; Diop, Soda; Birse, Ryan; Elmen, Lisa; Gan, Zhuohui; Kalvakuri, Sreehari; Pineda, Santiago; Reddy, Curran; Taylor, Erika; Trinh, Bosco; Vogler, Georg; Zarndt, Rachel; McCulloch, Andrew; Lee, Peter; Bhattacharya, Sharmila; Bodmer, Rolf; Ocorr, Karen 分享 收藏
Patient-specific genomics and cross-species functional analysis implicate LRP2 in hypoplastic left heart syndrome Theis, Jeanne L.; Vogler, Georg; Missinato, Maria A.; Li, Xing; Nielsen, Tanja; Zeng, Xin-Xin I.; Martinez-Fernandez, Almudena; Walls, Stanley M.; Kervadec, Anais; Kezos, James N.; Birker, Katja; Evans, Jared M.; O'Byrne, Megan M.; Fogarty, Zachary C.; Terzic, Andre; Grossfeld, Paul; Ocorr, Karen; Nelson, Timothy J.; Olson, Timothy M.; Colas, Alexandre R.; Bodmer, Rolf 分享 收藏
Silencing of CCR4-NOT complex subunits affects heart structure and function Elmen, Lisa; Volpato, Claudia B.; Kervadec, Anais; Pineda, Santiago; Kalvakuri, Sreehari; Alyari, Nakissa N.; Foco, Luisa; Pramstaller, Peter P.; Ocorr, Karen; Rossini, Alessandra; Cammarato, Anthony; Colas, Alexandre R.; Hicks, Andrew A.; Bodmer, Rolf 分享 收藏
De Novo Variants in CNOT1, a Central Component of the CCR4-NOT Complex Involved in Gene Expression and RNA and Protein Stability, Cause Neurodevelopmental Delay Vissers, Lisenka E. L. M.; Kalvakuri, Sreehari; de Boer, Elke; Geuer, Sinje; Oud, Machteld; van Outersterp, Inge; Kwint, Michael; Witmond, Melde; Kersten, Simone; Polla, Daniel L.; Weijers, Dilys; Begtrup, Amber; McWalter, Kirsty; Ruiz, Anna; Gabau, Elisabeth; Morton, Jenny E., V; Griffith, Christopher; Weiss, Karin; Gamble, Candace; Bartley, James; Vernon, Hilary J.; Brunet, Kendra; Ruivenkamp, Claudia; Kant, Sarina G.; Kruszka, Paul; Larson, Austin; Afenjar, Alexandra; de Villemeur, Thierry Billette; Nugent, Kimberly; Raymond, F. Lucy; Venselaar, Hanka; Demurger, Florence; Soler-Alfonso, Claudia; Li, Dong; Bhoj, Elizabeth; Hayes, Ian; Hamilton, Nina Powell; Ahmad, Ayesha; Fisher, Rachel; van den Born, Myrthe; Willems, Marjolaine; Sorlin, Arthur; Delanne, Julian; Moutton, Sebastien; Christophe, Philippe; Mau-Them, Frederic Tran; Vitobello, Antonio; Goel, Himanshu; Massingham, Lauren; Phornphutkul, Chanika; Schwab, Jennifer; Keren, Boris; Charles, Perrine; Vreeburg, Maaike; De Simone, Lenika; Hoganson, George; Iascone, Maria; Milani, Donatella; Evenepoel, Lucie; Revencu, Nicole; Ward, D. Isum; Burns, Kaitlyn; Krantz, Ian; Raible, Sarah E.; Murrell, Jill R.; Wood, Kathleen; Cho, Megan T.; van Bokhoven, Hans; Muenke, Maximilian; Kleefstra, Tjitske; Bodmer, Rolf; de Brouwer, Arjan P. M. 分享 收藏
分享 收藏
TGFB-INHB/activin signaling regulates age-dependent autophagy and cardiac health through inhibition of MTORC2 Chang, Kai; Kang, Ping; Liu, Ying; Huang, Kerui; Miao, Ting; Sagona, Antonia P.; Nezis, Ioannis P.; Bodmer, Rolf; Ocorr, Karen; Bai, Hua 分享 收藏
Model system identification of novel congenital heart disease gene candidates: focus on RPL13 Schroeder, Analyne M.; Allahyari, Massoud; Vogler, Georg; Missinato, Maria A.; Nielsen, Tanja; Yu, Michael S.; Theis, Jeanne L.; Larsen, Lars A.; Goyal, Preeya; Rosenfeld, Jill A.; Nelson, Timothy J.; Olson, Timothy M.; Colas, Alexandre R.; Grossfeld, Paul; Bodmer, Rolf 分享 收藏
分享 收藏
SLP-2 interacts with Parkin in mitochondria and prevents mitochondrial dysfunction in Parkin-deficient human iPSC-derived neurons and Drosophila (vol 26, pg 2412, 2017) Zanon, Alessandra; Kalvakuri, Sreehari; Rakovic, Aleksandar; Foco, Luisa; Guida, Marianna; Schwienbacher, Christine; Serafin, Alice; Rudolph, Franziska; Trilck, Michaela; Gruenewald, Anne; Stanslowsky, Nancy; Wegner, Florian; Giorgio, Valentina; Lavdas, Alexandros A.; Bodmer, Rolf; Pramstaller, Peter P.; Klein, Christine; Hicks, Andrew A.; Pichler, Irene; Philip, Seibler 分享 收藏
A homozygous KAT2B variant modulates the clinical phenotype of ADD3 eficiency in humans and flies (vol 14, e1007386, 2018) Goncalves, Sara; Patat, Julie; Guida, Maria Clara; Lachaussee, Noelle; Arrondel, Christelle; Helmstadter, Martin; Boyer, Olivia; Gribouval, Olivier; Gubler, Marie-Claire; Mollet, Geraldine; Rio, Marlene; Charbit, Marina; Bole-Feysot, Christine; Nitschke, Patrick; Huber, Tobias B.; Wheeler, Patricia G.; Haynes, Devon; Juusola, Jane; de Villemeur, Thierry Billette; Nava, Caroline; Afenjar, Alexandra; Keren, Boris; Bodmer, Rolf; Antignac, Corinne; Simons, Matias 分享 收藏
.png){kind=icon}
未登录.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
.png){kind=icon}
