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收藏Antigen-driven expansion of public clonal T-cell populations in inflammatory bowel diseases炎症性肠病中抗原驱动下的公共克隆T细胞群体扩增
Pesesky, Mitchell; Bharanikumar, Ramit; Le Bourhis, Lionel; ElAbd, Hesham; Rosati, Elisa; Carty, Cara L.; Singh, Namita; Bokemeyer, Bernd; Schreiber, Stefan; Goerg, Siegfried; Noceda, Marco Garcia; Chapfuwa, Paidamoyo; Gittelman, Rachel M.; May, Damon; Dines, Jennifer N.; Zhou, Wenyu; Kaplan, Ian M.; Snyder, Thomas M.; Jabran Zahid, Harus; Greissl, Julia; Chen-Harris, Haiyin; Howie, Bryan; Franke, Andre; Robins, Harlan S.; Allez, Matthieu 分享 收藏 分享 收藏 The role of epithelial STING in a genetic IBD Model of autophagy deficiency and its interplay with the Integrated stress responseSpringer, E.; Bornhaeuser, J.; Bakr, M.; van den Bossche, S.; Kakavand, N.; Yang, G.; Xiang, H.; Wu, Q.; Schreiber, S.; Welz, L.; Rosenstiel, P.; Aden, K. 分享 收藏 The microRNA Expression in Crypt-Top and Crypt-Bottom Colonic Epithelial Cell Populations Demonstrates Cell-Type Specificity and Correlates with Endoscopic Activity in Ulcerative ColitisInciuraite, Ruta; Ramonaite, Rima; Kupcinskas, Juozas; Dalgediene, Indre; Kulokiene, Ugne; Kiudelis, Vytautas; Varkalaite, Greta; Zvirbliene, Aurelija; Jonaitis, Laimas Virginijus; Kiudelis, Gediminas; Franke, Andre; Schreiber, Stefan; Juzenas, Simonas; Skieceviciene, Jurgita 分享 收藏 NF-κB/RelA controlled A20 limits TRAIL-induced apoptosis in pancreatic cancerGeismann, Claudia; Hauser, Charlotte; Grohmann, Frauke; Schneeweis, Christian; Boelter, Nico; Gundlach, Jan-Paul; Schneider, Gunter; Roecken, Christoph; Meinhardt, Christian; Schaefer, Heiner; Schreiber, Stefan; Arlt, Alexander 分享 收藏 The HSF1-CPT1a Pathway Is Differentially Regulated in NAFLD ProgressionBreternitz, Wiebke; Sandkuehler, Friedrich; Grohmann, Frauke; Hampe, Jochen; Brosch, Mario; Herrmann, Alexander; Schafmayer, Clemens; Meinhardt, Christian; Schreiber, Stefan; Arlt, Alexander; Geismann, Claudia 分享 收藏 DNA methyltransferase 3A controls intestinal epithelial barrier function and regeneration in the colonFazio, Antonella; Bordoni, Dora; Kuiper, Jan W. P.; Weber-Stiehl, Saskia; Stengel, Stephanie T.; Arnold, Philipp; Ellinghaus, David; Ito, Go; Tran, Florian; Messner, Berith; Henning, Anna; Bernardes, Joana P.; Haesler, Robert; Luzius, Anne; Imm, Simon; Hinrichsen, Finn; Franke, Andre; Huber, Samuel; Nikolaus, Susanna; Aden, Konrad; Schreiber, Stefan; Sommer, Felix; Natoli, Gioacchino; Mishra, Neha; Rosenstiel, Philip 分享 收藏 Autoantibodies targeting GPCRs and RAS-related molecules associate with COVID-19 severityCabral-Marques, Otavio; Halpert, Gilad; Schimke, Lena F.; Ostrinski, Yuri; Vojdani, Aristo; Baiocchi, Gabriela Crispim; Freire, Paula Paccielli; Filgueiras, Igor Salerno; Zyskind, Israel; Lattin, Miriam T.; Tran, Florian; Schreiber, Stefan; Marques, Alexandre H. C.; Placa, Desiree Rodrigues; Fonseca, Dennyson Leandro M.; Humrich, Jens Y.; Mueller, Antje; Giil, Lasse M.; Grasshoff, Hanna; Schumann, Anja; Hackel, Alexander; Junker, Juliane; Meyer, Carlotta; Ochs, Hans D.; Lavi, Yael Bublil; Scheibenbogen, Carmen; Dechend, Ralf; Jurisica, Igor; Schulze-Forster, Kai; Silverberg, Jonathan, I; Amital, Howard; Zimmerman, Jason; Heidecke, Harry; Rosenberg, Avi Z.; Riemekasten, Gabriela; Shoenfeld, Yehuda 分享 收藏 Cross-tissue transcriptome-wide association studies identify susceptibility genes shared between schizophrenia and inflammatory bowel diseaseUellendahl-Werth, Florian; Maj, Carlo; Borisov, Oleg; Juzenas, Simonas; Wacker, Eike Matthias; Jorgensen, Isabella Friis; Steiert, Tim Alexander; Bej, Saptarshi; Krawitz, Peter; Hoffmann, Per; Schramm, Christoph; Wolkenhauer, Olaf; Banasik, Karina; Brunak, Soren; Schreiber, Stefan; Karlsen, Tom Hemming; Degenhardt, Franziska; Noethen, Markus; Franke, Andre; Folseraas, Trine; Ellinghaus, David 分享 收藏 Epithelial X-Box Binding Protein 1 Coordinates Tumor Protein p53-Driven DNA Damage Responses and Suppression of Intestinal CarcinogenesisWelz, Lina; Kakavand, Nassim; Hang, Xiang; Laue, Georg; Ito, Go; Silva, Miguel Gomes; Plattner, Christina; Mishra, Neha; Tengen, Felicitas; Ogris, Christoph; Jesinghaus, Moritz; Wottawa, Felix; Arnold, Philipp; Kaikkonen, Leena; Stengel, Stefanie; Tran, Florian; Das, Saumya; Kaser, Arthur; Trajanoski, Zlatko; Blumberg, Richard; Roecken, Christoph; Saur, Dieter; Tschurtschenthaler, Markus; Schreiber, Stefan; Rosenstiel, Philip; Aden, Konrad 分享 收藏 Genome-wide study of a Neolithic Wartberg grave community reveals distinct HLA variation and hunter-gatherer ancestry新石器时代的Wartberg坟墓社区的全基因组研究揭示了独特的HLA变异和狩猎采集者血统Immel, Alexander; Pierini, Federica; Rinne, Christoph; Meadows, John; Barquera, Rodrigo; Szolek, Andras; Susat, Julian; Boehme, Lisa; Dose, Janina; Bonczarowska, Joanna; Drummer, Clara; Fuchs, Katharina; Ellinghaus, David; Kaessens, Jan Christian; Furholt, Martin; Kohlbacher, Oliver; Schade-Lindig, Sabine; Franke, Andre; Schreiber, Stefan; Krause, Johannes; Mueller, Johannes; Lenz, Tobias L.; Nebel, Almut; Krause-Kyora, Ben 分享 收藏 Exome-Wide Association Study Identifies FN3KRP and PGP as New Candidate Longevity GenesTorres, Guillermo G.; Nygaard, Marianne; Caliebe, Amke; Blanche, Helene; Chantalat, Sophie; Galan, Pilar; Lieb, Wolfgang; Christiansen, Lene; Deleuze, Jean-Francois; Christensen, Kaare; Strauch, Konstantin; Mueller-Nurasyid, Martina; Peters, Annette; Noethen, Markus M.; Hoffmann, Per; Flachsbart, Friederike; Schreiber, Stefan; Ellinghaus, David; Franke, Andre; Dose, Janina; Nebel, Almut 分享 收藏 Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19纵向多组学分析确定巨核细胞，红系细胞和浆母细胞的反应是严重新型冠状病毒肺炎的标志Bernardes, Joana P.; Mishra, Neha; Tran, Florian; Bahmer, Thomas; Best, Lena; Blase, Johanna, I; Bordoni, Dora; Franzenburg, Jeanette; Geisen, Ulf; Josephs-Spaulding, Jonathan; Koehler, Philipp; Kuenstner, Axel; Rosati, Elisa; Aschenbrenner, Anna C.; Bacher, Petra; Baran, Nathan; Boysen, Teide; Brandt, Burkhard; Bruse, Niklas; Doerr, Jonathan; Draeger, Andreas; Elke, Gunnar; Ellinghaus, David; Fischer, Julia; Forster, Michael; Franke, Andre; Franzenburg, Soeren; Frey, Norbert; Friedrichs, Anette; Fuss, Janina; Glueck, Andreas; Hamm, Jacob; Hinrichsen, Finn; Hoeppner, Marc P.; Imm, Simon; Junker, Ralf; Kaiser, Sina; Kan, Ying H.; Knoll, Rainer; Lange, Christoph; Laue, Georg; Lier, Clemens; Lindner, Matthias; Marinos, Georgios; Markewitz, Robert; Nattermann, Jacob; Noth, Rainer; Pickkers, Peter; Rabe, Klaus F.; Renz, Alina; Roecken, Christoph; Rupp, Jan; Schaffarzyk, Annika; Scheffold, Alexander; Schulte-Schrepping, Jonas; Schunk, Domagoj; Skowasch, Dirk; Ulas, Thomas; Wandinger, Klaus-Peter; Wittig, Michael; Zimmermann, Johannes; Busch, Hauke; Hoyer, Bimba F.; Kaleta, Christoph; Heyckendorf, Jan; Kox, Matthijs; Rybniker, Jan; Schreiber, Stefan; Schultze, Joachim L.; Rosenstiel, Philip 分享 收藏 Shared Genetics of Multiple System Atrophy and Inflammatory Bowel Disease多系统萎缩和炎症性肠病的共享遗传学Shadrin, Alexey A.; Mucha, Soren; Ellinghaus, David; Makarious, Mary B.; Blauwendraat, Cornelis; Sreelatha, Ashwin A. K.; Heras-Garvin, Antonio; Ding, Jinhui; Hammer, Monia; Foubert-Samier, Alexandra; Meissner, Wassilios G.; Rascol, Olivier; Pavy-Le Traon, Anne; Frei, Oleksandr; O'Connell, Kevin S.; Bahrami, Shahram; Schreiber, Stefan; Lieb, Wolfgang; Muller-Nurasyid, Martina; Schminke, Ulf; Homuth, Georg; Schmidt, Carsten O.; Nothen, Markus M.; Hoffmann, Per; Gieger, Christian; Wenning, Gregor; Gibbs, J. Raphael; Franke, Andre; Hardy, John; Stefanova, Nadia; Gasser, Thomas; Singleton, Andrew; Houlden, Henry; Scholz, Sonja W.; Andreassen, Ole A.; Sharma, Manu 分享 收藏 Protein-coding variants contribute to the risk of atopic dermatitis and skin-specific gene expressionMucha, Soren; Baurecht, Hansjorg; Novak, Natalija; Rodriguez, Elke; Bej, Saptarshi; Mayr, Gabriele; Emmert, Hila; Stoelzl, Dora; Gerdes, Sascha; Jung, Eun Suk; Degenhardt, Frauke; Huebenthal, Matthias; Ellinghaus, Eva; Kaessens, Jan Christian; Wienbrandt, Lars; Lieb, Wolfgang; Mueller-Nurasyid, Martina; Hotze, Melanie; Dand, Nick; Grosche, Sarah; Marenholz, Ingo; Arnold, Andreas; Homuth, Georg; Schmidt, Carsten O.; Wehkamp, Ulrike; Nothen, Markus M.; Hoffmann, Per; Paternoster, Lavinia; Standl, Marie; Bonnelykke, Klaus; Ahluwalia, Tarunveer S.; Bisgaard, Hans; Peters, Annette; Gieger, Christian; Waldenberger, Melanie; Schulz, Holger; Strauch, Konstantin; Werfel, Thomas; Lee, Young-Ae; Wolfien, Markus; Rosenstiel, Philip; Wolkenhauer, Olaf; Schreiber, Stefan; Franke, Andre; Weidinger, Stephan; Ellinghaus, David 分享 收藏 Epithelial RNase H2 Maintains Genome Integrity and Prevents Intestinal Tumorigenesis in MiceAden, Konrad; Bartsch, Kareen; Dahl, Joseph; Reijns, Martin A. M.; Esser, Daniela; Sheibani-Tezerji, Raheleh; Sinha, Anupam; Wottawa, Felix; Ito, Go; Mishra, Neha; Knittler, Katharina; Burkholder, Adam; Welz, Lina; van Es, Johan; Tran, Florian; Lipinski, Simone; Kakavand, Nassim; Boeger, Christine; Lucius, Ralph; von Schoenfels, Witigo; Schafmayer, Clemens; Lenk, Lennart; Chalaris, Athena; Clevers, Hans; Roecken, Christoph; Kaleta, Christoph; Rose-John, Stefan; Schreiber, Stefan; Kunkel, Thomas; Rabe, Bjoern; Rosenstiel, Philip 分享 收藏 ATG16L1 orchestrates interleukin-22 signaling in the intestinal epithelium via cGAS-STINGAden, Konrad; Tran, Florian; Ito, Go; Sheibani-Tezerji, Raheleh; Lipinski, Simone; Kuiper, Jan W.; Tschurtschenthaler, Markus; Saveljeva, Svetlana; Bhattacharyya, Joya; Haesler, Robert; Bartsch, Kareen; Luzius, Anne; Jentzsch, Marlene; Falk-Paulsen, Maren; Stengel, Stephanie T.; Welz, Lina; Schwarzer, Robin; Rabe, Bjoern; Barchet, Winfried; Krautwald, Stefan; Hartmann, Gunther; Pasparakis, Manolis; Blumberg, Richard S.; Schreiber, Stefan; Kaser, Arthur; Rosenstiel, Philip 分享 收藏 Neolithic and medieval virus genomes reveal complex evolution of hepatitis B新石器时代和中世纪病毒基因组揭示了乙型肝炎的复杂进化Krause-Kyora, Ben; Susat, Julian; Key, Felix M.; Kuehnert, Denise; Bosse, Esther; Immel, Alexander; Rinne, Christoph; Kornell, Sabin-Christin; Yepes, Diego; Franzenburg, Soeren; Heyne, Henrike O.; Meier, Thomas; Loesch, Sandra; Meller, Harald; Friederich, Susanne; Nicklisch, Nicole; Alt, Kurt W.; Schreiber, Stefan; Tholey, Andreas; Herbig, Alexander; Nebel, Almut; Krause, Johannes 分享 收藏 Ancient DNA study reveals HLA susceptibility locus for leprosy in medieval Europeans古代DNA研究揭示了中世纪欧洲人麻风病的HLA易感位点Krause-Kyora, Ben; Nutsua, Marcel; Boehme, Lisa; Pierini, Federica; Pedersen, Dorthe Dangvard; Kornell, Sabin-Christin; Drichel, Dmitriy; Bonazzi, Marion; Moebus, Lena; Tarp, Peter; Susat, Julian; Bosse, Esther; Willburger, Beatrix; Schmidt, Alexander H.; Sauter, Juergen; Franke, Andre; Wittig, Michael; Caliebe, Amke; Nothnagel, Michael; Schreiber, Stefan; Boldsen, Jesper L.; Lenz, Tobias L.; Nebel, Almut 分享 收藏 
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