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收藏Determination of tumor PSMA expression in prostate cancer from blood using a novel epigenomic liquid biopsy platform使用一种新型表观基因组液体活检平台对血液中前列腺癌的肿瘤PSMA表达进行测定
Ravi, P.; D'Ippolito, A.; Wurster, J.; Savignano, H.; Stoltenberg, H. A.; Trowbridge, R.; Borges, N.; Tamakloe, T.; Kieft, S.; Tran, V.; Guess, J.; Obrien, C.; Coyne, M.; Gorthi, A.; Painter, C.; Freedman, M.; Eaton, M.; Barrett, J. C.; Jacene, H.; Berchuck, J. E. 分享 收藏 分享 收藏 Novel liquid biopsy based determination of lung cancer histology using a comprehensive epigenomic platform reveals enhancer activity as a key determinant for accurate classificationGuess, Jamey; Gorthi, Aparna; D'ippolity, Anthony; Beagan, Jonathan; Clark, Travis; Coyne, Michael; Tamakloe, Tyrone; Tran, Baovy; Jeong, Hyun-Hwan; Cibulskis, Kristian; Sawaengsri, Hathairat; Chmielecki, Juliann; Painter, Corrie A.; Barrett, J. Carl; Eaton, Matthew 分享 收藏 Enhanced patient selection for anti-PD-L1 treatment in metastatic NSCLC with quantitative continuous scoring of PD-L1Lesniak, Jan Martin; Schick, Markus; Kunzke, Thomas; Pollastri, Federico; Vigueras-Guillen, Juan Pedro; Hessel, Harald; Haneder, Susanne; Sontakke, Pallavi; DaCosta, Karma; Alleze, Regina; Sade, Hadassah; Barrett, J. Carl; Schmidt, Gunter; Stewart, Ross 分享 收藏 A novel epigenomic profiling assay reveals disease biology and therapeutic targets in gastro-esophageal cancer from 1 ml of plasmaBeagan, Jonathan; Gorthi, Aparna; D'Ippolito, Anthony; Clark, Travis; Coyne, Michael; Tamakloe, Tyrone; Donahue, Amy; Baovy Tran; Jeong, Hyun-Hwan; Cibulskis, Kristian; Sawaengsri, Hathairat; Painter, Corrie A.; Chmielecki, Juliann; Barrett, J. Carl; Afreen, Mosammat Faria; Pandey, Aditya; Schechter, Ilexa Ashley; Taylor, Martin S.; Strickland, Matthew R.; Eaton, Matthew; Klempner, Samuel J. 分享 收藏 Comprehensive epigenomic profiling from plasma to inform therapy selection: A proof-of-concept study in cancerClark, Travis; Seo, Ji-Heui; D'Ippolito, Anthony; Gorthi, Aparna; Beagan, Jonathan; Guess, Jamey; Donahue, Amy; Greene, Mandy; Lau, Alyssa; Ramirez, Fernando; Cibulskis, Kristian; Jeong, Hyun-Hwan; Davidsohn, Matthew; Lakshminarayanam, Gitanjali; Coyne, Michael; Tran, Baovy; Tamakloe, Tyrone; Sawaengsri, Hathairat; Eid, Marc; Semaan, Karl; Fortunato, Brad; Painter, Corrie A.; Chmielecki, Juliann; Choueiri, Toni K.; Barrett, J. Carl; Otto, Geoff; Freedman, Matthew L.; Eaton, Matthew L.; Baca, Sylvan C. 分享 收藏 The ATR inhibitor ceralasertib potentiates cancer checkpoint immunotherapy by regulating the tumor microenvironmentATR抑制剂ceralasertib通过调节肿瘤微环境来增强癌症检查点免疫治疗Hardaker, Elizabeth L.; Sanseviero, Emilio; Karmokar, Ankur; Taylor, Devon; Milo, Marta; Michaloglou, Chrysis; Hughes, Adina; Mai, Mimi; King, Matthew; Solanki, Anisha; Magiera, Lukasz; Miragaia, Ricardo; Kar, Gozde; Standifer, Nathan; Surace, Michael; Gill, Shaan; Peter, Alison; Talbot, Sara; Tohumeken, Sehmus; Fryer, Henderson; Mostafa, Ali; Mulgrew, Kathy; Lam, Carolyn; Hoffmann, Scott; Sutton, Daniel; Carnevalli, Larissa; Calero-Nieto, Fernando J.; Jones, Gemma N.; Pierce, Andrew J.; Wilson, Zena; Campbell, David; Nyoni, Lynet; Martins, Carla P.; Baker, Tamara; de Almeida, Gilberto Serrano; Ramlaoui, Zainab; Bidar, Abdel; Phillips, Benjamin; Boland, Joseph; Iyer, Sonia; Barrett, J. Carl; Loembe, Arsene-Bienvenu; Fuchs, Serge Y.; Duvvuri, Umamaheswar; Lou, Pei-Jen; Nance, Melonie A.; Gomez Roca, Carlos Alberto; Cadogan, Elaine; Critichlow, Susan E.; Fawell, Steven; Cobbold, Mark; Dean, Emma; Valge-Archer, Viia; Lau, Alan; Gabrilovich, Dmitry I.; Barry, Simon T. 分享 收藏 Biomarker-directed targeted therapy plus durvalumab in advanced non-small-cell lung cancer: a phase 2 umbrella trial生物标志物定向靶向治疗联合durvalumab治疗晚期非小细胞肺癌: 2期伞形试验Besse, Benjamin; Pons-Tostivint, Elvire; Park, Keunchil; Hartl, Sylvia; Forde, Patrick M.; Hochmair, Maximilian J.; Awad, Mark M.; Thomas, Michael; Goss, Glenwood; Wheatley-Price, Paul; Shepherd, Frances A.; Florescu, Marie; Cheema, Parneet; Chu, Quincy S. C.; Kim, Sang-We; Morgensztern, Daniel; Johnson, Melissa L.; Cousin, Sophie; Kim, Dong-Wan; Moskovitz, Mor T.; Vicente, David; Aronson, Boaz; Hobson, Rosalind; Ambrose, Helen J.; Khosla, Sajan; Reddy, Avinash; Russell, Deanna L.; Keddar, Mohamed Reda; Conway, James P.; Barrett, J. Carl; Dean, Emma; Kumar, Rakesh; Dressman, Marlene; Jewsbury, Philip J.; Iyer, Sonia; Barry, Simon T.; Cosaert, Jan; Heymach, John V. 分享 收藏 Aligning tumor mutational burden (TMB) quantification across diagnostic platforms: phase II of the Friends of Cancer Research TMB Harmonization Project (vol 32, pg 1626, 2021)Vega, D. M.; Yee, L. M.; McShane, L. M.; Williams, P. M.; Chen, L.; Vilimas, T.; Fabrizio, D.; Funari, V.; Newberg, J.; Bruce, L. K.; Chen, S-J; Baden, J.; Barrett, J. Carl; Beer, P.; Butler, M.; Cheng, J-H; Conroy, J.; Cyanam, D.; Eyring, K.; Garcia, E.; Green, G.; Gregersen, V. R.; Hellmann, M. D.; Keefer, L. A.; Lasiter, L.; Lazar, A. J.; Li, M. -C; MacConaill, L. E.; Meier, K.; Mellert, H.; Pabla, S.; Pallavajjalla, A.; Pestano, G.; Salgado, R.; Samara, R.; Sokol, E. S.; Stafford, P.; Budczies, J.; Stenzinger, A.; Tom, W.; Valkenburg, K. C.; Wang, X. Z.; Weigman, V.; Xie, M.; Xie, Q.; Zehir, A.; Zhao, C.; Zhao, Y.; Stewart, M. D.; Allen, J. 分享 收藏 Pan-Tumor Analytical Validation and Osimertinib Clinical Validation in EGFR Mutant Non-Small-Cell Lung Cancer, Supporting the First Next-Generation Sequencing Liquid Biopsy in Vitro DiagnosticGray, Jhanelle E.; Han, Ji-Youn; Telaranta-Keerie, Aino; Huang, Xiangning; Kohlmann, Alexander; Hodge, Rachel; Rukazenkov, Yuri; Chmielecki, Juliann; Espenschied, Carin R.; Lefterova, Martina; Wu, Yi-Long; Ramalingam, Suresh S.; Barrett, J. Carl; Odegaard, Justin I. 分享 收藏 Longitudinal Circulating Tumor DNA Modeling to Predict Disease Progression in First-Line Mutant Epidermal Growth Factor Receptor Non-Small Cell Lung CancerJohnson, Martin; Traynor, Carlos Serra; Vishwanathan, Karthick; Overend, Philip; Hartmaier, Ryan; Markovets, Aleksandra; Chmielecki, Juliann; Mugundu, Ganesh M.; Barrett, J. Carl; Tomkinson, Helen; Ramalingam, Suresh S. 分享 收藏 GUIDE.MRD: A Consortium guiding multi-modal therapies against minimal residual disease (MRD) by liquid biopsy to assess implementation of circulating tumor DNA (ctDNA) in clinical practice to improve patient outcomesPantel, K.; Andersen, C. Lindbjerg; Schuuring, E.; Malats, N.; Heitzer, E.; Vat, L.; Kiernan, E.; Chin, E.; Barrett, C.; Kapp, R.; Thomas, M.; Gerling, M.; Reck, M.; Lohr, M.; Hofman, P.; Hiltermann, N.; Alix-Panabieres, C.; Smit, J.; Bolisetty, M.; Karasarides, M. 分享 收藏 分享 收藏 Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancer (14, 1070, 2023)Chmielecki, Juliann; Gray, Jhanelle E.; Cheng, Ying; Ohe, Yuichiro; Imamura, Fumio; Cho, Byoung Chul; Lin, Meng-Chih; Majem, Margarita; Shah, Riyaz; Rukazenkov, Yuri; Todd, Alexander; Markovets, Aleksandra; Barrett, J. Carl; Hartmaier, Ryan J.; Ramalingam, Suresh S. 分享 收藏 Immunomodulatory effects of ceralasertib in combination with durvalumab in patients with NSCLC and progression on anti-PD-(L)1 treatment (HUDSON, NCT03334617)Iyer, Sonia; Conway, James; Russell, Deanna; Reddy, Avinash; Cosaert, Jan; Barry, Simon; Dressman, Marlene; Mensi, Ilhem; Aronson, Boaz; Peters, Jane; Ambrose, Helen; Park, Keunchil; Forde, Patrick; Besse, Benjamin; Heymach, John V.; Barrett, J. Carl 分享 收藏 A unified computational pathology method to quantify HER2 expression from raw IHC and IF images in breast cancerBrieu, Nicolas; Drago, Joshua Z.; Kapil, Ansh; Hassan, Zonera; Shumilov, Anatoliy; Myers, Claire; Derakhshan, Fatemeh; Pareja, Fresia; Ratzon, Fanni; Ross, Dana; Reis-Filho, Jorge; Padel, Thomas; Spitzmuller, Andreas; Sachs, Christian C.; Fegerer, Felix; Khelifa, Sihem; Barrett, J. Carl; Schmidt, Gunter; Sade, Hadassah; Gustavson, Mark; Chandarlapaty, Sarat 分享 收藏 Background variability in plasma ctDNA levels in patients with advanced lung cancer in the absence of treatmentVega, Diana M.; Markovets, Aleksandra; Abbosh, Christopher; Quinn, Katie; Chang, Kyle; Wienke, Sara; Hartmaier, Ryan; Hellmann, Matthew; Barrett, J. Carl; Hodgson, Darren 分享 收藏 Misclassification of clonal hematopoietic mutations as tumor-derived confound accurate ctDNA-response assessment in patients with metastatic non-small-cell lung cancer: analyses from the phase 3 MYSTIC trialAbbosh, Chris; Kuziora, Michael; Stetson, Daniel; Lai, Zhongwu; Shrestha, Yashaswi; Labrousse, Paul; Shi, Xiaojin; Mann, Helen; Vega, Diana Merino; Hellmann, Matthew D.; Peters, Solange; Barrett, J. Carl; Hodgson, Darren 分享 收藏 Candidate mechanisms of acquired resistance to first-line osimertinib in EGFR-mutated advanced non-small cell lung cancerEGFR突变的晚期非小细胞肺癌对一线奥希替尼获得性耐药的候选机制Chmielecki, Juliann; Gray, Jhanelle E.; Cheng, Ying; Ohe, Yuichiro; Imamura, Fumio; Cho, Byoung Chul; Lin, Meng-Chih; Majem, Margarita; Shah, Riyaz; Rukazenkov, Yuri; Todd, Alexander; Markovets, Aleksandra; Barrett, J. Carl; Hartmaier, Ryan J.; Ramalingam, Suresh S. 分享 收藏 
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