未登录 A novel application tunnel in combination with medical training reduces stress induced by frequent intraperitoneal injections and blood draws in mice 一种新型应用隧道与医学训练相结合可减少小鼠因频繁腹腔注射和采血引起的应激反应 Schlutt, Anne; Riesner, Katarina; Kochan, Merle; Mess, Ann-Kathrin; Jahn, Denise; Lurje, Isabella; Werner, Wiebke; Heymann, Felix; Kershaw, Olivia; Tacke, Frank; Hiebl, Bernhard; Hammerich, Linda 分享 收藏
The Role of Glycocalyx Diversity and Thickness for Nanoparticle Internalization in M1-/M2-like Macrophages 糖萼多样性和厚度对M1-/M2-like巨噬细胞中纳米颗粒内化的作用 Liu, Yu; He, Yubei; Xu, Han; Remmo, Amani; Wiekhorst, Frank; Heymann, Felix; Liu, Hanyang; Schellenberger, Eyk; Haeckel, Akvile; Hauptmann, Ralf; Taupitz, Matthias; Shen, Yu; Yilmaz, Emine Yaren; Mueller, Dominik N.; Heidemann, Luisa; Schmidt, Robin; Savic, Lynn Jeanette 分享 收藏
Dissecting Acute Drug-Induced Hepatotoxicity and Therapeutic Responses of Steatotic Liver Disease Using Primary Mouse Liver and Blood Cells in a Liver-On-A-Chip Model Liu, Hanyang; Yin, Guo; Kohlhepp, Marlene Sophia; Schumacher, Fabian; Hundertmark, Jana; Hassan, Mohamed I. Abdelwahab; Heymann, Felix; Puengel, Tobias; Kleuser, Burkhard; Mosig, Alexander Sandy; Tacke, Frank; Guillot, Adrien 分享 收藏
C-C chemokine receptor type 7 (CCR7) regulates hepatic CD8+ T cell homeostasis and response to acute liver injury Niemietz, Patricia; Peiseler, Moritz; Kohlhepp, Marlene; Horn, Paul; Matchett, Kylie; Wang, Yuting; Haas, Leon; Zhang, Tianjiao; Bruneau, Alix; Guillot, Adrien; Berger, Hilmar; Liepelt, Anke; Warzecha, Klaudia; Demske, Catharina; Moeckel, Diana; Lammers, Twan; Henderson, Neil; Heymann, Felix; Tacke, Frank 分享 收藏
M cell maturation and cDC activation determine the onset of adaptive immune priming in the neonatal Peyer's patch M细胞成熟和cDC激活决定了新生儿Peyer补丁中适应性免疫启动的开始 Torow, Natalia; Li, Ronghui; Hitch, Thomas Charles Adrian; Mingels, Clemens; Al Bounny, Shahed; van Best, Niels; Stange, Eva-Lena; Simons, Britta; Maie, Tiago; Ruettger, Lennart; Gubbi, Narasimha Murthy Keshava Prasad; Abbott, Darryl Adelaide; Benabid, Adam; Gadermayr, Michael; Runge, Solveig; Treichel, Nicole; Merhof, Dorit; Rosshart, Stephan Patrick; Jehmlich, Nico; Hand, Timothy Wesley; von Bergen, Martin; Heymann, Felix; Pabst, Oliver; Clavel, Thomas; Tacke, Frank; Lelouard, Hugues; Costa, Ivan Gesteira; Hornef, Mathias Walter 分享 收藏
Establishment of gastrointestinal assembloids to study the interplay between epithelial crypts and their mesenchymal niche Lin, Manqiang; Hartl, Kimberly; Heuberger, Julian; Beccaceci, Giulia; Berger, Hilmar; Li, Hao; Liu, Lichao; Muellerke, Stefanie; Conrad, Thomas; Heymann, Felix; Woehler, Andrew; Tacke, Frank; Rajewsky, Nikolaus; Sigal, Michael 分享 收藏
Hepatic C-X-C chemokine receptor type 6-expressing innate lymphocytes limit detrimental myeloid hyperactivation in acute liver injury Heymann, Felix; Mossanen, Jana C.; Peiseler, Moritz; Niemietz, Patricia M.; David, Bruna Araujo; Krenkel, Oliver; Liepelt, Anke; Carneiro, Matheus Batista; Kohlhepp, Marlene S.; Kubes, Paul; Tacke, Frank 分享 收藏
Mapping the hepatic immune landscape identifies monocytic macrophages as key drivers of steatohepatitis and cholangiopathy progression Guillot, Adrien; Winkler, Marc; Silva Afonso, Milessa; Aggarwal, Abhishek; Lopez, David; Berger, Hilmar; Kohlhepp, Marlene S.; Liu, Hanyang; Ozdirik, Burcin; Eschrich, Johannes; Ma, Jing; Peiseler, Moritz; Heymann, Felix; Pendem, Swetha; Mahadevan, Sangeetha; Gao, Bin; Diehl, Lauri; Gupta, Ruchi; Tacke, Frank 分享 收藏
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Telomere Shortening in Peripheral Leukocytes Is Associated With Poor Survival in Cancer Patients Treated With Immune Checkpoint Inhibitor Therapy Rolles, Benjamin; Gorgulho, Joao; Tometten, Mareike; Roderburg, Christoph; Vieri, Margherita; Abels, Anne; Vucur, Mihael; Heymann, Felix; Tacke, Frank; Bruemmendorf, Tim H.; Luedde, Tom; Beier, Fabian; Loosen, Sven H. 分享 收藏
Serum levels of soluble B and T lymphocyte attenuator predict overall survival in patients undergoing immune checkpoint inhibitor therapy for solid malignancies Gorgulho, Joao; Roderburg, Christoph; Heymann, Felix; Schulze-Hagen, Maximilian; Beier, Fabian; Vucur, Mihael; Kather, Jakob N.; Laleh, Narmin Ghaffari; Tacke, Frank; Bruemmendorf, Tim H.; Luedde, Tom; Loosen, Sven H. 分享 收藏
MAdCAM-1/α4β7 Integrin-Mediated Lymphocyte/Endothelium Interactions Exacerbate Acute Immune-Mediated Hepatitis in Mice Schippers, Angela; Huebel, Jessica; Heymann, Felix; Clahsen, Thomas; Eswaran, Sreepradha; Schlepuetz, Sarah; Pullen, Robin; Gassler, Nikolaus; Tenbrock, Klaus; Tacke, Frank; Wagner, Norbert 分享 收藏
Differential effects of selective- and pan-PPAR agonists on experimental steatohepatitis and hepatic macrophages Lefere, Sander; Puengel, Tobias; Hundertmark, Jana; Penners, Christian; Frank, Anna Katharina; Guillot, Adrien; de Muynck, Kevin; Heymann, Felix; Adarbes, Vanessa; Defrene, Evelyne; Estivalet, Celine; Geerts, Anja; Devisscher, Lindsey; Wettstein, Guillaume; Tacke, Frank 分享 收藏
CX3CR1 Mediates the Development of Monocyte-Derived Dendritic Cells during Hepatic Inflammation Sutti, Salvatore; Bruzzi, Stefania; Heymann, Felix; Liepelt, Anke; Krenkel, Oliver; Toscani, Alberto; Ramavath, Naresh Naik; Cotella, Diego; Albano, Emanuele; Tacke, Frank 分享 收藏
Novel 3D analysis using optical tissue clearing documents the evolution of murine rapidly progressive glomerulonephritis Puelles, Victor G.; Fleck, David; Ortz, Lena; Papadouri, Stella; Strieder, Thiago; Boehner, Alexander M. C.; van der Wolde, James W.; Vogt, Michael; Saritas, Turgay; Kuppe, Christoph; Fuss, Astrid; Menzel, Sylvia; Klinkhammer, Barbara M.; Mueller-Newen, Gerhard; Heymann, Felix; Decker, Leon; Braun, Fabian; Kretz, Oliver; Huber, Tobias B.; Susaki, Etsuo A.; Ueda, Hiroki R.; Boor, Peter; Floege, Juergen; Kramann, Rafael; Kurts, Christian; Bertram, John F.; Spehr, Marc; Nikolic-Paterson, David J.; Moeller, Marcus J. 分享 收藏
Liver fibrosis affects the targeting properties of drug delivery systems to macrophage subsets in vivo Ergen, Can; Niemietz, Patricia Maria; Heymann, Felix; Baues, Maike; Gremse, Felix; Pola, Robert; van Bloois, Louis; Storm, Gert; Kiessling, Fabian; Trautwein, Christian; Luedde, Tom; Lammers, Twan; Tacke, Frank 分享 收藏
CXCR6 Inhibits Hepatocarcinogenesis by Promoting Natural Killer T- and CD4+ T-Cell-Dependent Control of Senescence CXCR6通过促进自然杀伤T和CD4 T细胞依赖性衰老控制来抑制肝癌发生 Mossanen, Jana C.; Kohlhepp, Marlene; Wehr, Alexander; Krenkel, Oliver; Liepelt, Anke; Roeth, Anjali A.; Moeckel, Diana; Heymann, Felix; Lammers, Twan; Gassler, Nikolaus; Hermann, Juliane; Jankowski, Joachim; Neumann, Ulf P.; Luedde, Tom; Trautwein, Christian; Tacke, Frank 分享 收藏
Polypropylene mesh implantation for hernia repair causes myeloid cell-driven persistent inflammation Heymann, Felix; von Trotha, Klaus-Thilo; Preisinger, Christian; Lynen-Jansen, Petra; Roeth, Anjali A.; Geiger, Melanie; Geisler, Lukas Jonathan; Frank, Lanna Katharina; Conze, Joachim; Luedde, Tom; Trautwein, Christian; Binneboesel, Marcel; Neumann, Ulf P.; Tacke, Frank 分享 收藏
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Regardless of etiology, progressive renal disease causes ultrastructural and functional alterations of peritubular capillaries Babickova, Janka; Klinkhammer, Barbara M.; Buhl, Eva M.; Djudjaj, Sonja; Hoss, Mareike; Heymann, Felix; Tacke, Frank; Floege, Juergen; Becker, Jan U.; Boor, Peter 分享 收藏
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