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Efficacy and safety of larotrectinib in patients with TRK fusion gastrointestinal cancer 拉罗替尼在TRK融合胃肠道癌症患者中的有效性与安全性 Qi, Changsong; Shen, Lin; Andre, Thierry; Chung, Hyun Cheol; Cannon, Timothy L.; Garralda, Elena; Italiano, Antoine; Rieke, Damian T.; Liu, Tianshu; Burcoveanu, Domnita-Ileana; Neu, Natascha; Mussi, Chiara E.; Xu, Rui-Hua; Hong, David S.; Drilon, Alexander; Berlin, Jordan 分享 收藏
Executive Summary of the American Radium Society on Appropriate Use Criteria for Nonoperative Management of Rectal Adenocarcinoma: Systematic Review and Guidelines Anker, Christopher J.; Tchelebi, Leila T.; Selfridge, J. Eva; Jabbour, Salma K.; Akselrod, Dmitriy; Cataldo, Peter; Abood, Gerard; Berlin, Jordan; Hallemeier, Christopher L.; Jethwa, Krishan R.; Kim, Ed; Kennedy, Timothy; Lee, Percy; Sharma, Navesh; Small, William; Williams, Vonetta M.; Russo, Suzanne 分享 收藏
Omission of 5-Fluorouracil Bolus From Multidrug Regimens for Advanced Gastrointestinal Cancers: A Multicenter Cohort Study 从多药方案中省略5-Fluorouracil Bolus用于晚期胃肠道癌症：一项多中心队列研究 Peng, Chengwei; Saffo, Saad; Oberstein, Paul E.; Shusterman, Michael; Thomas, Charlene; Becker, Daniel J.; Berlin, Jordan D.; Leichman, Lawrence P.; Boursi, Ben; Nagar, Anil B.; Yu, Shun 分享 收藏
Safety, PK, immune activation, and clinical outcomes with RBS2418 treatment, an oral ENPP1 inhibitor, alone or in combination with pembrolizumab in advanced solid tumors 安全性、PK（药代动力学）、免疫激活及临床结局：RBS2418（一种口服ENPP1抑制剂）单药或联合pembrolizumab治疗晚期实体瘤的疗效观察 Marron, T.; Segar, J.; Berlin, J. D.; Boccia, R.; Spira, A. I.; Powderly, J.; Chen, C.; Wainberg, Z. A.; Schanzer, J. M.; Glenn, J.; Klumpp, K.; Csiki, I.; Misleh, J. G. 分享 收藏
Preliminary safety and clinical activity of ASP3082, a first-in-class, KRAS G12D selective protein degrader in adults with advanced pancreatic (PC), colorectal (CRC), and non-small cell lung cancer (NSCLC) 一流的KRAS G12D选择性蛋白降解剂ASP3082在成人晚期胰腺癌 (PC)，结直肠癌 (CRC) 和非小细胞肺癌 (NSCLC) 中的初步安全性和临床活性 Park, W.; Kasi, A.; Spira, A. I.; Berlin, J. D.; Wang, J. S.; Herzberg, B.; Kuboki, Y.; Kitano, S.; Pelster, M.; Goldman, J. W.; Morgensztern, D.; Kondo, S.; Janne, P. A.; Fujii, H.; Lee, H-J.; Gill, S.; Saci, A.; Lorusso, P.; Tolcher, A. W. 分享 收藏
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Circulating microRNAs in association with pancreatic cancer risk within 5 years Wang, Cong; Cai, Hui; Cai, Qiuyin; Wu, Jie; Stolzenberg-Solomon, Rachael; Guo, Xingyi; Zhu, Claire; Gao, Yu-Tang; Berlin, Jordan; Ye, Fei; Zheng, Wei; Setiawan, Veronica Wendy; Shu, Xiao-Ou 分享 收藏
A Phase I/IIa clinical trial (TranStar101) to evaluate the safety, tolerability and pharmacokinetics of OSEMITAMAB administered as monotherapy or in combination with nivolumab or standard of care in patients with locally advanced or metastatic solid tumors Janjigian, Yelena; Tolcher, Anthony; Mehta, Rutika; Cecchini, Michael; Van Tine, Brian; Kundranda, Madappa; Olatunji, Alese; Patel, Manish R.; Berlin, Jordan; Rocha-Lima, Caio Max Sao Pedro; Monga, Dulabh; Ben George; Scott, Aaron; Xia, Zhenzhong; Elsafy, Mohamed; Jones, Erikca; Yao, Zhenling; Qi, Chuan; Germa, Caroline; Gabrail, Nash 分享 收藏
A phase I study to evaluate the safety, pharmacokinetics, and pharmacodynamics of PF-06939999 (PRMT5 inhibitor) in patients with selected advanced or metastatic tumors with high incidence of splicing factor gene mutations Rodon, J.; Rodriguez, E.; Maitland, M. L.; Tsai, F. y. -c.; Socinski, M. A.; Berlin, J. D.; Thomas, J. S.; Al Baghdadi, T.; Wang, I. -m.; Guo, C.; Golmakani, M.; Clark, L. N.; Gazdoiu, M.; Li, M.; Tolcher, A. W. 分享 收藏
Associations of circulating miRNAs with pancreatic cancer risk differ by years between blood collection & and cancer diagnosis Cai, Hui; Setiawan, Veronica Wendy; Guo, Xingyi; Wu, Jie; Stolzenberg-Solomon, Rachael Z.; Zhu, Claire; Gao, Yu-Tang; Berlin, Jordan; Ye, Fei; Cai, Qiuyin; Zheng, Wei; Shu, Xiao-Ou 分享 收藏
A phase I study of ATR inhibitor gartisertib (M4344) as a single agent and in combination with carboplatin in patients with advanced solid tumours Burris, Howard A.; Berlin, Jordan; Arkenau, Tobias; Cote, Gregory M.; Lolkema, Martijn P.; Ferrer-Playan, Jordi; Kalapur, Anup; Bolleddula, Jayaprakasam; Locatelli, Giuseppe; Goddemeier, Thomas; Gounaris, Ioannis; de Bono, Johann 分享 收藏
NUC-3373 in combination with irinotecan (NUFIRI) or oxaliplatin (NUFOX) and bevacizumab for second-line treatment of patients with advanced colorectal cancer (NuTide:302) Khan, Khurum; Mukherjee, Uma; Schlechter, Benjamin L.; Ciombor, Kristen K.; Skolariki, Aglaia; Coveler, Andrew L.; Graham, Janet S.; Peters, Mary Linton; Cohen, Stacey A.; Mettu, Niharika; Marijon, Helene; Cosgrove, David; McKissock, Fiona G.; Oelmann, Elisabeth; Bloss, Jeffrey D.; Blagden, Sarah P.; de Gramont, Aimery; Berlin, Jordan; Evans, T. R. Jeffry 分享 收藏
Phase II study of NUC-3373, leucovorin, irinotecan (NUFIRI) plus bevacizumab vs FOLFIRI plus bevacizumab for the second-line treatment of patients with advanced/metastatic colorectal cancer (NuTide:323) Wilson, Richard H.; Ciombor, Kristen K.; Coveler, Andrew L.; Graham, Janet S.; Schlechter, Benjamin L.; George, Thomas J.; Elez, Elena; Evans, T. R. Jeffry; Berlin, Jordan; de Gramont, Aimery; McKissock, Fiona G.; Oelmann, Elisabeth; Bloss, Jeffrey D.; Martini, Giulia; Bennouna, Jaafar; Modest, Dominik P.; Taieb, Julien; Tabernero, Josep 分享 收藏
Ibrutinib combination therapy for advanced gastrointestinal and genitourinary tumours: results from a phase 1b/2 study Oh, Do-Youn; Maqueda, Maria Alsina; Quinn, David I.; O'Dwyer, Peter J.; Chau, Ian; Kim, Sun Young; Duran, Ignacio; Castellano, Daniel; Berlin, Jordan; Mellado, Begona; Williamson, Stephen K.; Lee, Keun-Wook; Marti, Francisca; Mathew, Paul; Saif, Muhammad Wasif; Wang, Ding; Chong, Elizabeth; Hilger-Rolfe, Jacqueline; Dean, James P.; Arkenau, Hendrik-Tobias 分享 收藏
Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance 提高早期剂量发现临床试验的报告质量和影响: CONSORT剂量发现扩展 (CONSORT-DEFINE) 指南 Yap, Christina; Solovyeva, Olga; de Bono, Johann; Rekowski, Jan; Patel, Dhrusti; Jaki, Thomas; Mander, Adrian; Evans, Thomas R. Jeffry; Peck, Richard; Hayward, Kathryn S.; Hopewell, Sally; Ursino, Moreno; Rantell, Khadija Rerhou; Calvert, Melanie; Lee, Shing; Kightley, Andrew; Ashby, Deborah; Chan, An-Wen; Garrett-Mayer, Elizabeth; Isaacs, John; Golub, Robert; Kholmanskikh, Olga; Richards, Dawn; Boix, Oliver; Matcham, James; Seymour, Lesley; Ivy, S. Percy; Marshall, Lynley, V; Hommais, Antoine; Liu, Rong; Tanaka, Yoshiya; Berlin, Jordan; Espinasse, Aude; Dimairo, Munyaradzi; Weir, Christopher J. 分享 收藏
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