Jeffery L. Kutok - Publications, H-index & Citations

Jeffery L. Kutok

university of california irvine

91H指数

410论文数

3.1W被引数

收录论文 69

发表时间

EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes

CANCER RESEARCH

IF16.6

2023-09-25

OAAI

Huang, Yeying; Durall, R. Taylor; Luong, Nhi M.; Hertzler, Hans J.; Huang, Julianna; Gokhale, Prafulla C.; Leeper, Brittaney A.; Persky, Nicole S.; Root, David E.; Anekal, Praju V.; Montero Llopis, Paula D. L. M.; David, Clement N.; Kutok, Jeffery L.; Raimondi, Alejandra; Saluja, Karan; Luo, Jia; Zahnow, Cynthia A.; Adane, Biniam; Stegmaier, Kimberly; Hawkins, Catherine E.; Ponne, Christopher; Le, Quan; Shapiro, Geoffrey I.; Lemieux, Madeleine E.; Eagen, Kyle P.; French, Christopher A.

Duvelisib eliminates CLL B Cells, impairs CLL-supporting cells, and overcomes ibrutinib resistance in a patient-derived xenograft model

CANCER RESEARCH

IF16.6

2023-04-04

PREAI

Chen, Shih-Shih; Barrientos, Jacqueline C.; Ferrer, Gerardo; Ravichandran, Priyadarshini; Ibrahim, Michael; Kieso, Yasmine; Kutok, Jeffery L.; Peluso, Marisa; Sharma, Sujata; Weaver, David T.; Pachter, Jonathan A.; Rai, Kanti R.; Chiorazzi, Nicholas

Socs-1 inhibits TEL-JAK2-mediated transformation of hematopoietic cells through inhibition of JAK2 kinase activity and induction of proteasome-mediated degradation

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-28

160

OAAI

Frantsve, J; Schwaller, J; Sternberg, DW; Kutok, J; Gilliland, DG

BAL1 and BBAP are regulated by a gamma interferon-responsive bidirectional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrate

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

118

OAAI

Juszczynski, Przemyslaw; Kutok, Jeffery L.; Li, Cheng; Mitra, Joydeep; Aguiar, Ricardo C. T.; Shipp, Margaret A.

Emi1 Maintains Genomic Integrity during Zebrafish Embryogenesis and Cooperates with p53 in Tumor Suppression Emi1在斑马鱼胚胎发生过程中维持基因组完整性，并与p53协同抑制肿瘤

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-21

OAAI

Rhodes, Jennifer; Amsterdam, Adam; Sanda, Takaomi; Moreau, Lisa A.; McKenna, Keith; Heinrichs, Stefan; Ganem, Neil J.; Ho, Karen W.; Neuberg, Donna S.; Johnston, Adam; Ahn, Yebin; Kutok, Jeffery L.; Hromas, Robert; Wray, Justin; Lee, Charles; Murphy, Carly; Radtke, Ina; Downing, James R.; Fleming, Mark D.; MacConaill, Laura E.; Amatruda, James F.; Gutierrez, Alejandro; Galinsky, Ilene; Stone, Richard M.; Ross, Eric A.; Pellman, David S.; Kanki, John P.; Look, A. Thomas

Inhibition of de novo lipogenesis targets androgen receptor signaling in castration-resistant prostate cancer 抑制去势抵抗性前列腺癌的从头脂肪生成靶向雄激素受体信号传导

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2018-12-21

209

OAAI

Zadra, Giorgia; Ribeiro, Caroline F.; Chetta, Paolo; Ho, Yeung; Cacciatore, Stefano; Gao, Xueliang; Syamala, Sudeepa; Bango, Clyde; Photopoulos, Cornelia; Huang, Ying; Tyekucheva, Svitlana; Bastos, Debora C.; Tchaicha, Jeremy; Lawney, Brian; Uo, Takuma; D'Anello, Laura; Csibi, Alfredo; Kalekar, Radha; Larimer, Benjamin; Ellis, Leigh; Butler, Lisa M.; Morrissey, Colm; McGovern, Karen; Palombella, Vito J.; Kutok, Jeffery L.; Mahmood, Umar; Bosari, Silvano; Adams, Julian; Peluso, Stephane; Dehm, Scott M.; Plymate, Stephen R.; Loda, Massimo

The selective Phosphoinoside-3-Kinase p110d inhibitor IPI-3063 Potently suppresses B cell survival, Proliferation, and Differentiation

FRONTIERS IN IMMUNOLOGY

IF5.9

2017-06-30

OAAI

Chiu, Honyin; Mallya, Sharmila; Phuongthao Nguyen; Mai, Annie; Jackson, Leandra V.; Winkler, David G.; DiNitto, Jonathan P.; Brophy, Erin E.; McGovern, Karen; Kutok, Jeffery L.; Fruman, David A.

Duvelisib treatment is associated with altered expression of apoptotic regulators that helps in sensitization of chronic lymphocytic leukemia cells to venetoclax (ABT-199)

LEUKEMIA

IF13.4

2016-12-26

OAAI

Patel, V. M.; Balakrishnan, K.; Douglas, M.; Tibbitts, T.; Xu, E. Y.; Kutok, J. L.; Ayers, M.; Sarkar, A.; Guerrieri, R.; Wierda, W. G.; O'Brien, S.; Jain, N.; Stern, H. M.; Gandhi, V.

Combination of duvelisib with either ibrutinib or dexamethasone prevents mTOR-dependent feedback in aggressive B-cell lymphoma cell lines

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

White, Kerry; Murphy, Erin; Faia, Kerrie; Proctor, Jennifer; Kosmider, Nicole; Pink, Melissa; Goldstein, Stanley; McGovern, Karen; Kutok, Jeffery L.

Checkpoint blockade therapy is improved by altering the immune suppressive microenvironment with IPI-549, a potent and selective inhibitor of PI3K-gamma, in preclinical models

CANCER RESEARCH

IF16.6

2016-07-15

PREAI

De Henau, Olivier; Merghoub, Taha; Winkler, David; Sharma, Sujata; Pink, Melissa; Tchaicha, Jeremy; Rausch, Matthew; Proctor, Jennifer; Kosmider, Nicole; Soglia, John; Palombella, Vito; Kutok, Jeffery L.; Wolchok, Jedd D.; McGovern, Karen

The phosphoinositide-3-kinase (PI3K)-delta and gamma inhibitor, IPI-145 (Duvelisib), overcomes signals from the PI3K/AKT/S6 pathway and promotes apoptosis in CLL

LEUKEMIA

IF13.4

2015-04-28

143

OAAI

Balakrishnan, K.; Peluso, M.; Fu, M.; Rosin, N. Y.; Burger, J. A.; Wierda, W. G.; Keating, M. J.; Faia, K.; O'Brien, S.; Kutok, J. L.; Gandhi, V.

Impact of promoter polymorphisms in key regulators of the intrinsic apoptosis pathway on the outcome of childhood acute lymphoblastic leukemia

HAEMATOLOGICA

IF7.9

2013-09-13

OAAI

Sanchez, Rocio; St-Cyr, Janick; Lalonde, Marie-Eve; Healy, Jasmine; Richer, Chantal; Gagne, Vincent; Laverdiere, Caroline; Silverman, Lewis B.; Sallan, Stephen E.; Neuberg, Donna; Kutok, Jeffery L.; Kritikou, Ekaterini A.; Krajinovic, Maja; Sinnett, Daniel

Impact of Hemochromatosis Gene Mutations on Cardiac Status in Doxorubicin-Treated Survivors of Childhood High-Risk Leukemia

CANCER

IF5.1

2013-07-16

121

OAAI

Lipshultz, Steven E.; Lipsitz, Stuart R.; Kutok, Jeffery L.; Miller, Tracie L.; Colan, Steven D.; Neuberg, Donna S.; Stevenson, Kristen E.; Fleming, Mark D.; Sallan, Stephen E.; Franco, Vivian I.; Henkel, Jacqueline M.; Asselin, Barbara L.; Athale, Uma H.; Clavell, Luis A.; Michon, Bruno; Laverdiere, Caroline; Larsen, Eric; Kelly, Kara M.; Silverman, Lewis B.

Conditional inactivation of p53 in mature B cells promotes generation of nongerminal center-derived B-cell lymphomas

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2013-02-04

OAAI

Gostissa, Monica; Bianco, Julia M.; Malkin, Daniel J.; Kutok, Jeffery L.; Rodig, Scott J.; Morse, Herbert C., III; Bassing, Craig H.; Alt, Frederick W.

A Unique Galectin Signature in Human Prostate Cancer Progression Suggests Galectin-1 as a Key Target for Treatment of Advanced Disease

CANCER RESEARCH

IF16.6

2013-01-02

155

OAAI

Laderach, Diego J.; Gentilini, Lucas D.; Giribaldi, Laura; Delgado, Victor Cardenas; Nugnes, Lorena; Croci, Diego O.; Al Nakouzi, Nader; Sacca, Paula; Casas, Gabriel; Mazza, Osvaldo; Shipp, Margaret A.; Vazquez, Elba; Chauchereau, Anne; Kutok, Jeffery L.; Rodig, Scott J.; Elola, Maria T.; Compagno, Daniel; Rabinovich, Gabriel A.

Impact of Saridegib (IPI-926) On Smoothened Ciliary Localization and Hedgehog Pathway Activity

EUROPEAN JOURNAL OF CANCER

IF7.1

2012-11-01

PREAI

Peluso, M.; Faia, K.; Campbell, V.; DiNitto, J.; Harari, J.; Proctor, J.; Pink, M.; McGovern, K.; Kutok, J.; Read, M.

Cisplatin benefit is predicted by immunohistochemical analysis of DNA repair proteins in squamous cell carcinoma but not adenocarcinoma: theranostic modeling by NSCLC constituent histological subclasses

ANNALS OF ONCOLOGY

IF65.4

2012-09-01

OAAI

Pierceall, W. E.; Olaussen, K. A.; Rousseau, V.; Brambilla, E.; Sprott, K. M.; Andre, F.; Pignon, J-P.; Le Chevalier, T.; Pirker, R.; Jiang, C.; Filipits, M.; Chen, Y.; Kutok, J. L.; Weaver, D. T.; Ward, B. E.; Soria, J-C.

Emerging Targeted Therapies for Lymphoid Malignancies

ARCHIVES OF PATHOLOGY & LABORATORY MEDICINE

IF3.2

2012-05-01

PREAI

Pozdnyakova, Olga; Kutok, Jeffery L.; Rodig, Scott J.

Activated ALK collaborates with MYCN in neuroblastoma pathogenesis

CANCER RESEARCH

IF16.6

2012-04-01

PREAI

Zhu, Shizhen; Lee, Jeong-Soo; Guo, Feng; Shin, Jimann; Perez-Atayde, Antonio R.; Kutok, Jeffery L.; Rodig, Scott J.; Neuberg, Donna S.; Helman, Daniel; Feng, Hui; Stewart, Rodney A.; Wang, Wenchao; George, Rani E.; Kanki, John; Look, A. Thomas

Molecular Ontogeny of Donor-Derived Follicular Lymphomas Occurring after Hematopoietic Cell Transplantation

CANCER DISCOVERY

IF33.3

2012-01-12

OAAI

Weigert, Oliver; Kopp, Nadja; Lane, Andrew A.; Yoda, Akinori; Dahlberg, Suzanne E.; Neuberg, Donna; Bahar, Anita Y.; Chapuy, Bjoern; Kutok, Jeffery L.; Longtine, Janina A.; Kuo, Frank C.; Haley, Terry; Salois, Maura; Sullivan, Timothy J.; Fisher, David C.; Fox, Edward A.; Rodig, Scott J.; Antin, Joseph H.; Weinstock, David M.

研究方向