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Inhibition of the angiotensin II type 2 receptor AT2R is a novel therapeutic strategy for glioblastoma Perryman, Richard; Renziehausen, Alexander; Shaye, Hamidreza; Kostagianni, Androniki D.; Tsiailanis, Antonis D.; Thorne, Thomas; Chatziathanasiadou, Maria, V; Sivolapenko, Gregory B.; El Mubarak, Mohamed Ahmed; Han, Gye Won; Zarzycka, Barbara; Katritch, Vsevolod; Lebon, Guillaume; Lo Nigro, Cristiana; Lattanzio, Laura; Morse, Sophie, V; Choi, James J.; O'Neill, Kevin; Kanaki, Zoi; Klinakis, Apostolos; Crook, Tim; Cherezov, Vadim; Tzakos, Andreas G.; Syed, Nelofer 分享 收藏
Primary outcome of the phase III SYD985.002/TULIP trial comparing [vic-]trastuzumab duocarmazine to physician's choice treatment in patients with pre-treated HER2-positive locally advanced or metastatic breast cancer Manich, C. Saura; O'Shaughnessy, J.; Aftimos, P. G.; van den Tweel, E.; Oesterholt, M.; Escriva-de-Romani, S. I.; Tueux, N. Quenel; Tan, T. J.; Lim, J. S.; Ladoire, S.; Armstrong, A.; Crook, T.; Stradella, A.; Bianchi, G.; Mulder, R.; Koper, N.; Turner, N. 分享 收藏
Enhancement of glioblastoma multiforme therapy through a novel Quercetin-Losartan hybrid Tsiailanis, Antonis D.; Renziehausen, Alexander; Kiriakidi, Sofia; Vrettos, Eirinaios I.; Markopoulos, Georgios S.; Sayyad, Nisar; Hirmiz, Baydaa; Aguilar, Marie-Isabel; Del Borgo, Mark P.; Kolettas, Evangelos; Widdop, Robert E.; Mavromoustakos, Thomas; Crook, Tim; Syed, Nelofer; Tzakos, Andreas G. 分享 收藏
Encyclopedic tumour analysis guided treatments with conventional drugs outperform available alternatives in refractory cancers Crook, T.; Vaid, A.; Limaye, S.; Page, R.; Patil, D.; Akolkar, D.; Datta, V.; Ghaisas, A.; Patil, R.; Singh, H.; Srinivasan, A.; Apurwa, S.; Datar, R. 分享 收藏
Collagen Prolyl Hydroxylases Are Bifunctional Growth Regulators in Melanoma Atkinson, Aithne; Renziehausen, Alexander; Wang, Hexiao; Lo Nigro, Cristiana; Lattanzio, Laura; Merlano, Marco; Rao, Bhavya; Weir, Lynda; Evans, Alan; Matin, Rubeta; Harwood, Catherine; Szlosarek, Peter; Pickering, J. Geoffrey; Fleming, Colin; Sim, Van Ren; Li, Su; Vasta, James T.; Raines, Ronald T.; Boniol, Mathieu; Thompson, Alastair; Proby, Charlotte; Crook, Tim; Syed, Nelofer 分享 收藏
Development of a validated LC-MS/MS method for the in vitro and in vivo quantitation of sunitinib in glioblastoma cells and cancer patients Chatziathanasiadou, Maria, V; Stylos, Evgenios K.; Giannopoulou, Efstathia; Spyridaki, Maria-Helen; Briasoulis, Evangelos; Kalofonos, Haralabos P.; Crook, Tim; Syed, Nelofer; Sivolapenko, Gregory B.; Tzakos, Andreas G. 分享 收藏
Development and validation of simple step protein precipitation UHPLC-MS/MS methods for quantitation of temozolomide in cancer patient plasma samples El Mubarak, Mohamed A.; Stylos, Evgenios K.; Chatziathanasiadou, Maria, V; Danika, Charikleia; Alexiou, George A.; Tsekeris, Periklis; Renziehausen, Alexander; Crook, Tim; Syed, Nelofer; Sivolapenko, Gregory B.; Tzakos, Andreas G. 分享 收藏
Efficacy of arginine depletion by ADI-PEG20 in an intracranial model of GBM Przystal, Justyna Magdalena; Hajji, Nabil; Khozoie, Combiz; Renziehausen, Alexander; Zeng, Qingyu; Abaitua, Fernando; Hajitou, Amin; Suwan, Keittisak; Want, Elizabeth; Bomalaski, John; Szlosarek, Peter; O'Neill, Kevin; Crook, Tim; Syed, Nelofer 分享 收藏
The renin angiotensin system (RAS) mediates bifunctional growth regulation in melanoma and is a novel target for therapeutic intervention Renziehausen, Alexander; Wang, Hexiao; Rao, Bhavya; Weir, Lynda; Lo Nigro, Cristiana; Lattanzio, Laura; Merlano, Marco; Vega-Rioja, Antonio; del Carmen Fernandez-Carranco, Maria; Hajji, Nabil; Matin, Rubeta; Harwood, Catherine; Li, Su; Sim, Van Ren; O'Neill, Kevin; Evans, Alan; Thompson, Alastair; Szlosarek, Peter; Fleming, Colin; Stebbing, Justin; Proby, Charlotte; Tzakos, Andreas G.; Syed, Nelofer; Crook, Tim 分享 收藏
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Splicing factors and the role of Navitoclax in drug-resistant ovarian cancer Coley, Helen M.; Lattanzio, Laura; Garrone, Ornella; Merlano, Marco; Vivenza, Daniela; Lo Nigro, Cristiana; Syed, Nelofer; Thompson, Alistair; Rao, Bhavya; Crook, Tim 分享 收藏
Identification of Endoglin as an epigenetically regulated tumour-suppressor gene in lung cancer 鉴定Endoglin作为肺癌中表观遗传调节的肿瘤抑制基因 O'Leary, K.; Shia, A.; Cavicchioli, F.; Haley, V.; Comino, A.; Merlano, M.; Mauri, F.; Walter, K.; Lackner, M.; Wischnewsky, M. B.; Crook, T.; Lo Nigro, C.; Schmid, P. 分享 收藏
Paclitaxel resistance increases oncolytic adenovirus efficacy via upregulated CAR expression and dysfunctional cell cycle control Ingemarsdotter, Carin K.; Tookman, Laura A.; Browne, Ashley; Pirlo, Katrina; Cutts, Rosalind; Chelela, Claude; Khurrum, Karisma F.; Leung, Elaine Y. L.; Dowson, Suzanne; Webber, Lee; Khan, Iftekhar; Ennis, Darren; Syed, Nelofer; Crook, Tim R.; Brenton, James D.; Lockley, Michelle; McNeish, Iain A. 分享 收藏
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Electronic Sculpting of Ligand-GPCR Subtype Selectivity: The Case of Angiotensin II Magnani, Francesca; Pappas, Charalamfos G.; Crook, Tim; Magafa, Vassiliki; Cordopatis, Paul; Ishiguro, Susumu; Ohta, Naomi; Selent, Jana; Bosnyak, Sanja; Jones, Emma S.; Gerothanassis, Ioannis P.; Tamura, Masaaki; Widdop, Robert E.; Tzakos, Andreas G. 分享 收藏
Prognostic and Therapeutic Impact of Argininosuccinate Synthetase 1 Control in Bladder Cancer as Monitored Longitudinally by PET Imaging Allen, Michael D.; Phuong Luong; Hudson, Chantelle; Leyton, Julius; Delage, Barbara; Ghazaly, Essam; Cutts, Rosalind; Yuan, Ming; Syed, Nelofer; Lo Nigro, Cristiana; Lattanzio, Laura; Chmielewska-Kassassir, Malgorzata; Tomlinson, Ian; Roylance, Rebecca; Whitaker, Hayley C.; Warren, Anne Y.; Neal, David; Frezza, Christian; Beltran, Luis; Jones, Louise J.; Chelala, Claude; Wu, Bor-Wen; Bomalaski, John S.; Jackson, Robert C.; Lu, Yong-Jie; Crook, Tim; Lemoine, Nicholas R.; Mather, Stephen; Foster, Julie; Sosabowski, Jane; Avril, Norbert; Li, Chien-Feng; Szlosarek, Peter W. 分享 收藏
Methylated Tissue Factor Pathway Inhibitor 2 (TFP12) DNA in Serum Is a Biomarker of Metastatic Melanoma Lo Nigro, Cristiana; Wang, Hexiao; McHugh, Angela; Lattanzio, Laura; Matin, Rubeta; Harwood, Catherine; Syed, Nelofer; Hatzimichael, Eleftheria; Briasoulis, Evangelos; Merlano, Marco; Evans, Alan; Thompson, Alastair; Leigh, Irene; Fleming, Colin; Inman, Gareth J.; Proby, Charlotte; Crook, Tim 分享 收藏
Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma Syed, N.; Langer, J.; Janczar, K.; Singh, P.; Lo Nigro, C.; Lattanzio, L.; Coley, H. M.; Hatzimichael, E.; Bomalaski, J.; Szlosarek, P.; Awad, M.; O'Neil, K.; Roncaroli, F.; Crook, T. 分享 收藏
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