未登录 Hair follicle gene expression profiling in the SubPopulations and InteRmediate Outcome Measures in COPD Study (SPIROMICS) SPIROMICS研究中亚人群和中间结局测量指标的毛囊基因表达谱分析 Buschur, Kristina L.; Martorella, Molly; Garcia-Flores, Renee; Smith, Benjamin M.; Ziosi, Marcello; Barjaktarevic, Igor; Bleecker, Eugene R.; Christenson, Stephanie A.; Comellas, Alejandro P.; Criner, Gerard J.; Dransfield, Mark T.; Hansel, Nadia N.; Kaner, Robert J.; Krishnan, Jerry A.; Meyers, Deborah A.; Oelsner, Elizabeth C.; Ortega, Victor E.; Paine III, Robert; Woodruff, Prescott G.; Barr, R. Graham; Lappalainen, Tuuli 分享 收藏
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Novel risk loci encompassing genes influencing STAT3, GPCR, and oxidative stress signaling are associated with co-morbid GERD and COPD 包含影响STAT3、GPCR和氧化应激信号的基因的新风险位点与GERD和COPD共病相关 Wilson, Ava C.; Rocco, Alison; Chiles, Joe; Srinivasasainagendra, Vinodh; Labaki, Wassim; Meyers, Deborah; Hidalgo, Bertha; Irvin, Marguerite R.; Bhatt, Surya P.; Tiwari, Hemant; Mcdonald, Merry-Lynn 分享 收藏
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Paradoxical bronchodilator response is associated with increased risk of asthma exacerbations Fakhry, Battoul; Chedraoui, Celine; Sleiman, Joelle; Attaway, Amy; Carr, Tara; Gaston, Benjamin; Hu, Bo; Meyers, Deborah; Ortega, Victor E.; Bleecker, Eugene R.; Zein, Joe 分享 收藏
Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes Keener, Rebecca; Chhetri, Surya B.; Connelly, Carla J.; Taub, Margaret A.; Conomos, Matthew P.; Weinstock, Joshua; Ni, Bohan; Strober, Benjamin; Aslibekyan, Stella; Auer, Paul L.; Barwick, Lucas; Becker, Lewis C.; Blangero, John; Bleecker, Eugene R.; Brody, Jennifer A.; Cade, Brian E.; Celedon, Juan C.; Chang, Yi-Cheng; Cupples, L. Adrienne; Custer, Brian; Freedman, Barry I.; Gladwin, Mark T.; Heckbert, Susan R.; Hou, Lifang; Irvin, Marguerite R.; Isasi, Carmen R.; Johnsen, Jill M.; Kenny, Eimear E.; Kooperberg, Charles; Minster, Ryan L.; Naseri, Take; Viali, Satupa'itea; Nekhai, Sergei; Pankratz, Nathan; Peyser, Patricia A.; Taylor, Kent D.; Telen, Marilyn J.; Wu, Baojun; Yanek, Lisa R.; Yang, Ivana V.; Albert, Christine; Arnett, Donna K.; Ashley-Koch, Allison E.; Barnes, Kathleen C.; Bis, Joshua C.; Blackwell, Thomas W.; Boerwinkle, Eric; Burchard, Esteban G.; Carson, April P.; Chen, Zhanghua; Chen, Yii-Der Ida; Darbar, Dawood; de Andrade, Mariza; Ellinor, Patrick T.; Fornage, Myriam; Gelb, Bruce D.; Gilliland, Frank D.; He, Jiang; Islam, Talat; Kaab, Stefan; Kardia, Sharon L. R.; Kelly, Shannon; Konkle, Barbara A.; Kumar, Rajesh; Loos, Ruth J. F.; Martinez, Fernando D.; McGarvey, Stephen T.; Meyers, Deborah A.; Mitchell, Braxton D.; Montgomery, Courtney G.; North, Kari E.; Palmer, Nicholette D.; Peralta, Juan M.; Raby, Benjamin A.; Redline, Susan; Rich, Stephen S.; Roden, Dan; Rotter, Jerome I.; Ruczinski, Ingo; Schwartz, David; Sciurba, Frank; Shoemaker, M. Benjamin; Silverman, Edwin K.; Sinner, Moritz F.; Smith, Nicholas L.; Smith, Albert V.; Tiwari, Hemant K.; Vasan, Ramachandran S.; Weiss, Scott T.; Williams, L. Keoki; Zhang, Yingze; Ziv, Elad; Raffield, Laura M.; Reiner, Alexander P.; Arvanitis, Marios; Greider, Carol W.; Mathias, Rasika A.; Battle, Alexis 分享 收藏
A common polymorphism in the Intelectin-1 gene influences mucus plugging in severe asthma Everman, Jamie L.; Sajuthi, Satria P.; Liegeois, Maude A.; Jackson, Nathan D.; Collet, Erik H.; Peters, Michael C.; Chioccioli, Maurizio; Moore, Camille M.; Patel, Bhavika B.; Dyjack, Nathan; Powell, Roger; Rios, Cydney; Montgomery, Michael T.; Eng, Celeste; Elhawary, Jennifer R.; Mak, Angel C. Y.; Hu, Donglei; Huntsman, Scott; Salazar, Sandra; Feriani, Luigi; Fairbanks-Mahnke, Ana; Zinnen, Gianna L.; Michel, Cole R.; Gomez, Joe; Zhang, Xing; Medina, Vivian; Chu, Hong Wei; Cicuta, Pietro; Gordon, Erin D.; Zeitlin, Pamela; Ortega, Victor E.; Reisdorph, Nichole; Dunican, Eleanor M.; Tang, Monica; Elicker, Brett M.; Henry, Travis S.; Bleecker, Eugene R.; Castro, Mario; Erzurum, Serpil C.; Israel, Elliot; Levy, Bruce D.; Mauger, David T.; Meyers, Deborah A.; Sumino, Kaharu; Gierada, David S.; Hastie, Annette T.; Moore, Wendy C.; Denlinger, Loren C.; Jarjour, Nizar N.; Schiebler, Mark L.; Wenzel, Sally E.; Woodruff, Prescott G.; Rodriguez-Santana, Jose; Pearson, Chad G.; Burchard, Esteban G.; Fahy, John V.; Seibold, Max A. 分享 收藏
New genetic signals for lung function highlight pathways and chronic obstructive pulmonary disease associations across multiple ancestries (vol 51, pg 481, 2019) 跨多个祖先的肺功能突出通路和慢性阻塞性肺疾病关联的新遗传信号 (第51卷，481页，2019) Shrine, Nick; Guyatt, Anna L.; Erzurumluoglu, A. Mesut; Jackson, Victoria E.; Hobbs, Brian D.; Melbourne, Carl A.; Batini, Chiara; Fawcett, Katherine A.; Song, Kijoung; Sakornsakolpat, Phuwanat; Li, Xingnan; Boxall, Ruth; Reeve, Nicola F.; Obeidat, Ma'en; Zhao, Jing Hua; Wielscher, Matthias; Weiss, Stefan; Kentistou, Katherine A.; Cook, James P.; Sun, Benjamin B.; Zhou, Jian; Hui, Jennie; Karrasch, Stefan; Imboden, Medea; Harris, Sarah E.; Marten, Jonathan; Enroth, Stefan; Kerr, Shona M.; Surakka, Ida; Vitart, Veronique; Lehtimaeki, Terho; Allen, Richard J.; Bakke, Per S.; Beaty, Terri H.; Bleecker, Eugene R.; Bosse, Yohan; Brandsma, Corry-Anke; Chen, Zhengming; Crapo, James D.; Danesh, John; DeMeo, Dawn L.; Dudbridge, Frank; Ewert, Ralf; Gieger, Christian; Gulsvik, Amund; Hansell, Anna L.; Hao, Ke; Hoffman, Joshua D.; Hokanson, John E.; Homuth, Georg; Joshi, Peter K.; Joubert, Philippe; Langenberg, Claudia; Li, Xuan; Li, Liming; Lin, Kuang; Lind, Lars; Locantore, Nicholas; Luan, Jian'an; Mahajan, Anubha; Maranville, Joseph C.; Murray, Alison; Nickle, David C.; Packer, Richard; Parker, Margaret M.; Paynton, Megan L.; Porteous, David J.; Prokopenko, Dmitry; Qiao, Dandi; Rawal, Rajesh; Runz, Heiko; Sayers, Ian; Sin, Don D.; Smith, Blair H.; Artigas, Maria Soler; Sparrow, David; Tal-Singer, Ruth; Timmers, Paul R. H. J.; Van den Berge, Maarten; Whittaker, John C.; Woodruff, Prescott G.; Yerges-Armstrong, Laura M.; Troyanskaya, Olga G.; Raitakari, Olli T.; Kaehoenen, Mika; Polasek, Ozren; Gyllensten, Ulf; Rudan, Igor; Deary, Ian J.; Probst-Hensch, Nicole M.; Schulz, Holger; James, Alan L.; Wilson, James F.; Stubbe, Beate; Zeggini, Eleftheria; Jarvelin, Marjo-Riitta; Wareham, Nick; Silverman, Edwin K.; Hayward, Caroline; Morris, Andrew P.; Butterworth, Adam S.; Scott, Robert A.; Walters, Robin G.; Meyers, Deborah A.; Cho, Michael H.; Strachan, David P.; Hall, Ian P.; Tobin, Martin D.; Wain, Louise V. 分享 收藏
Protein-Protein interactive networks identified in bronchoalveolar lavage of severe compared to nonsevere asthma Hastie, Annette T.; Bishop, Andrew C.; Khan, Mohammad S.; Bleecker, Eugene R.; Castro, Mario; Denlinger, Loren C.; Erzurum, Serpil C.; Fahy, John V.; Israel, Elliot; Levy, Bruce D.; Mauger, David T.; Meyers, Deborah A.; Moore, Wendy C.; Ortega, Victor E.; Peters, Stephen P.; Wenzel, Sally E.; Steele, Chad H. 分享 收藏
Comparison of Asthma Phenotypes in Severe Asthma Cohorts (SARP, U-BIOPRED, ProAR and COREA) From 4 Continents 来自四大洲的严重哮喘队列 (SARP，u-biopred，ProAR和COREA) 中哮喘表型的比较 Park, So-Young; Fowler, Stephen; Shaw, Dominic E.; Adcock, Ian M.; Sousa, Ana R.; Djukanovic, Ratko; Dahlen, Sven-Erik; Sterk, Peter J.; Kermani, Nazanin Zounemat; Calhoun, William; Israel, Elliot; Castro, Mario; Mauger, Dave; Meyers, Deborah; Bleecker, Eugene; Moore, Wendy; Busse, William; Jarjour, Nizar; Denlinger, Loren; Levy, Bruce; Choi, Byoung-Hwui; Kim, Sae-Hoon; Jang, An-Soo; Lee, Taehoon; Cho, Young-Joo; Shin, Yoo Seob; Cho, Sang-Heon; Won, Sungho; Cruz, Alvaro A.; Wenzel, Sally E.; Chung, Kian Fan; Kim, Tae-Bum 分享 收藏
Genetic and T2 biomarkers linked to the efficacy of HDM sublingual immunotherapy in asthma Hoof, Ilka; Bonnelykke, Klaus; Stranzl, Thomas; Brand, Stephanie; Li, Xingnan; Shamji, Mohamed H.; Meyers, Deborah A.; Bateman, Eric D.; Bleecker, Eugene; Andersen, Peter Sejer 分享 收藏
A Polygenic Risk Score for Idiopathic Pulmonary Fibrosis and Interstitial Lung Abnormalities 特发性肺纤维化和间质性肺异常的多基因风险评分 Moll, Matthew; Peljto, Anna L.; Kim, John S.; Xu, Hanfei; Debban, Catherine L.; Chen, Xianfeng; Menon, Aravind; Putman, Rachel K.; Ghosh, Auyon J.; Saferali, Aabida; Nishino, Mizuki; Hatabu, Hiroto; Hobbs, Brian D.; Hecker, Julian; McDermott, Gregory; Sparks, Jeffrey A.; Wain, Louise V.; Allen, Richard J.; Tobin, Martin D.; Raby, Benjamin A.; Chun, Sung; Silverman, Edwin K.; Zamora, Ana C.; Ortega, Victor E.; Garcia, Christine K.; Barr, R. Graham; Bleecker, Eugene R.; Meyers, Deborah A.; Kaner, Robert J.; Rich, Stephen S.; Manichaikul, Ani; Rotter, Jerome I.; Dupuis, Josee; O'Connor, George T.; Fingerlin, Tasha E.; Hunninghake, Gary M.; Schwartz, David A.; Cho, Michael H. 分享 收藏
Multi-ancestry genome-wide association analyses improve resolution of genes and pathways influencing lung function and chronic obstructive pulmonary disease risk (vol 55, pg 410, 2023) 多血统全基因组关联分析可改善影响肺功能和慢性阻塞性肺疾病风险的基因和通路的分辨率 (第55卷，410页，2023) Shrine, Nick; Izquierdo, Abril G.; Chen, Jing; Packer, Richard; Hall, Robert J.; Guyatt, Anna L.; Batini, Chiara; Thompson, Rebecca J.; Pavuluri, Chandan; Malik, Vidhi; Hobbs, Brian D.; Moll, Matthew; Kim, Wonji; Tal-Singer, Ruth; Bakke, Per; Fawcett, Katherine A.; John, Catherine; Coley, Kayesha; Piga, Noemi Nicole; Pozarickij, Alfred; Lin, Kuang; Millwood, Iona Y.; Chen, Zhengming; Li, Liming; Wijnant, Sara R. A.; Lahousse, Lies; Brusselle, Guy; Uitterlinden, Andre G.; Manichaikul, Ani; Oelsner, Elizabeth C.; Rich, Stephen S.; Barr, R. Graham; Kerr, Shona M.; Vitart, Veronique; Brown, Michael R.; Wielscher, Matthias; Imboden, Medea; Jeong, Ayoung; Bartz, Traci M.; Gharib, Sina A.; Flexeder, Claudia; Karrasch, Stefan; Gieger, Christian; Peters, Annette; Stubbe, Beate; Hu, Xiaowei; Ortega, Victor E.; Meyers, Deborah A.; Bleecker, Eugene R.; Gabriel, Stacey B.; Gupta, Namrata; Smith, Albert Vernon; Luan, Jian'an; Zhao, Jing-Hua; Hansen, Ailin F.; Langhammer, Arnulf; Willer, Cristen; Bhatta, Laxmi; Porteous, David; Smith, Blair H.; Campbell, Archie; Sofer, Tamar; Lee, Jiwon; Daviglus, Martha L.; Yu, Bing; Lim, Elise; Xu, Hanfei; O'Connor, George T.; Thareja, Gaurav; Albagha, Omar M. E.; Suhre, Karsten; Granell, Raquel; Faquih, Tariq O.; Hiemstra, Pieter S.; Slats, Annelies M.; Mullin, Benjamin H.; Hui, Jennie; James, Alan; Beilby, John; Patasova, Karina; Hysi, Pirro; Koskela, Jukka T.; Wyss, Annah B.; Jin, Jianping; Sikdar, Sinjini; Lee, Mikyeong; May-Wilson, Sebastian; Pirastu, Nicola; Kentistou, Katherine A.; Joshi, Peter K.; Timmers, Paul R. H. J.; Williams, Alexander T.; Free, Robert C.; Wang, Xueyang; Morrison, John L.; Gilliland, Frank D.; Chen, Zhanghua; Wang, Carol A.; Foong, Rachel E.; Harris, Sarah E.; Taylor, Adele; Redmond, Paul; Cook, James P.; Mahajan, Anubha; Lind, Lars; Palviainen, Teemu; Lehtimaki, Terho; Raitakari, Olli T.; Kaprio, Jaakko; Rantanen, Taina; Pietilainen, Kirsi H.; Cox, Simon R.; Pennell, Craig E.; Hall, Graham L.; Gauderman, W. James; Brightling, Chris; Wilson, James F.; Vasankari, Tuula; Laitinen, Tarja; Salomaa, Veikko; Mook-Kanamori, Dennis O.; Timpson, Nicholas J.; Zeggini, Eleftheria; Dupuis, Josee; Hayward, Caroline; Brumpton, Ben; Langenberg, Claudia; Weiss, Stefan; Homuth, Georg; Schmidt, Carsten Oliver; Probst-Hensch, Nicole; Jarvelin, Marjo-Riitta; Morrison, Alanna C.; Polasek, Ozren; Rudan, Igor; Lee, Joo-Hyeon; Sayers, Ian; Rawlins, Emma L.; Dudbridge, Frank; Silverman, Edwin K.; Strachan, David P.; Walters, Robin G.; Morris, Andrew P.; London, Stephanie J.; Cho, Michael H.; Wain, Louise V.; Hall, Ian P.; Tobin, Martin D. 分享 收藏
CCL5 is a potential bridge between type 1 and type 2 inflammation in asthma Gauthier, Marc; Kale, Sagar Laxman; Oriss, Timothy B.; Gorry, Michael; Ramonell, Richard P.; Dalton, Kathryn; Ray, Prabir; Fahy, John V.; Seibold, Max A.; Castro, Mario; Jarjour, Nizar; Gaston, Benjamin; Bleecker, Eugene R.; Meyers, Deborah A.; Moore, Wendy; Hastie, Annette T.; Israel, Elliot; Levy, Bruce D.; Mauger, David; Erzurum, Serpil; Comhair, Suzy A.; Wenzel, Sally E.; Ray, Anuradha 分享 收藏
Genetic control of mRNA splicing as a potential mechanism for incomplete penetrance of rare coding variants mRNA剪接的遗传控制是稀有编码变体不完全外显率的潜在机制 Einson, Jonah; Glinos, Dafni; Boerwinkle, Eric; Castaldi, Peter; Darbar, Dawood; de Andrade, Mariza; Ellinor, Patrick; Fornage, Myriam; Gabriel, Stacey; Germer, Soren; Gibbs, Richard; Hersh, Craig P.; Johnsen, Jill; Kaplan, Robert; Konkle, Barbara A.; Kooperberg, Charles; Nassir, Rami; Loos, Ruth J. F.; Meyers, Deborah A.; Mitchell, Braxton D.; Psaty, Bruce; Vasan, Ramachandran S.; Rich, Stephen S.; Rienstra, Michael; Rotter, Jerome, I; Saferali, Aabida; Shoemaker, Moore Benjamin; Silverman, Edwin; Smith, Albert Vernon; Mohammadi, Pejman; Castel, Stephane E.; Iossifov, Ivan; Lappalainen, Tuuli 分享 收藏
Large scale proteomic studies create novel privacy considerations Hill, Andrew C.; Guo, Claire; Litkowski, Elizabeth M.; Manichaikul, Ani W.; Yu, Bing; Konigsberg, Iain R.; Gorbet, Betty A.; Lange, Leslie A.; Pratte, Katherine A.; Kechris, Katerina J.; DeCamp, Matthew; Coors, Marilyn; Ortega, Victor E.; Rich, Stephen S.; Rotter, Jerome I.; Gerzsten, Robert E.; Clish, Clary B.; Curtis, Jeffrey L.; Hu, Xiaowei; Obeidat, Ma-en; Morris, Melody; Loureiro, Joseph; Ngo, Debby; O'Neal, Wanda K.; Meyers, Deborah A.; Bleecker, Eugene R.; Hobbs, Brian D.; Cho, Michael H.; Banaei-Kashani, Farnoush; Bowler, Russell P. 分享 收藏
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