未登录 Clinical outcome of biomarker-guided therapies in adult neuro-oncology patients: An update from the Tubingen molecular tumor board cohort 成人神经肿瘤患者生物标志物指导治疗的临床结局：图宾根分子肿瘤委员会队列的更新 Rieger, David; Becker, Hannes; Walter, Bianca; Dorner, Lorenz; Kurz, Sylvia C.; Niyazi, Maximilian; Bodensohn, Raphael; Neumann, Manuela; Riess, Olaf; Schroeder, Christopher; Ballin, Nadja; Ott, Alexander; Roggia, Cristiana; Ossowski, Stephan; Fend, Falko; Singer, Stephan; Nahnsen, Sven; Kohlbacher, Oliver; Ernemann, Ulrike; Sundberg Malek, Holly; Schittenhelm, Jens; Bitzer, Michael; Malek, Nisar; Tatagiba, Marcos; Renovanz, Mirjam; Tabatabai, Ghazaleh 分享 收藏
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CLINICAL OUTCOME OF BIOMARKER-GUIDED THERAPIES IN ADULT NEURO-ONCOLOGY PATIENTS: AN UPDATE FROM THE TÜBINGEN MOLECULAR TUMOR BOARD COHORT 生物标志物指导疗法在成人神经肿瘤学患者中的临床疗效：图宾根分子肿瘤委员会队列的研究进展 Rieger, D.; Becker, H.; Walter, B.; Doerner, L.; Kurz, S.; Gani, C.; Neumann, M.; Riess, O.; Schroeder, C.; Ossowski, S.; Fend, F.; Singer, S.; Nahnsen, S.; Ernemann, U.; Sundberg-Malek, H.; Schittenhelm, J.; Bitzer, M.; Malek, N.; Tatagiba, M.; Renovanz, M.; Tabatabai, G. 分享 收藏
Deciphering distinct genetic risk factors for FTLD-TDP pathological subtypes via whole-genome sequencing 通过全基因组测序破译ftld-tdp病理亚型的不同遗传危险因素 Pottier, Cyril; Kuecuekali, Fahri; Baker, Matt; Batzler, Anthony; Jenkins, Gregory D.; van Blitterswijk, Marka; Vicente, Cristina T.; De Coster, Wouter; Wynants, Sarah; van de Walle, Pieter; Ross, Owen A.; Murray, Melissa E.; Faura, Julia; Haggarty, Stephen J.; van Rooij, Jeroen GJ.; Mol, Merel O.; Hsiung, Ging-Yuek R.; Graff, Caroline; Oeijerstedt, Linn; Neumann, Manuela; Asmann, Yan; Mcdonnell, Shannon K.; Baheti, Saurabh; Josephs, Keith A.; Whitwell, Jennifer L.; Bieniek, Kevin F.; Forsberg, Leah; Heuer, Hilary; Lago, Argentina Lario; Geier, Ethan G.; Yokoyama, Jennifer S.; Oddi, Alexis P.; Flanagan, Margaret; Mao, Qinwen; Hodges, John R.; Kwok, John B.; Domoto-Reilly, Kimiko; Synofzik, Matthis; Wilke, Carlo; Onyike, Chiadi; Dickerson, Bradford C.; Evers, Bret M.; Dugger, Brittany N.; Munoz, David G.; Keith, Julia; Zinman, Lorne; Rogaeva, Ekaterina; Suh, Eunran; Gefen, Tamar; Geula, Changiz; Weintraub, Sandra; Diehl-Schmid, Janine; Farlow, Martin R.; Edbauer, Dieter; Woodruff, Bryan K.; Caselli, Richard J.; Donker Kaat, Laura L.; Huey, Edward D.; Reiman, Eric M.; Mead, Simon; King, Andrew; Roeber, Sigrun; Nana, Alissa L.; Ertekin-Taner, Nilufer; Knopman, David S.; Petersen, Ronald C.; Petrucelli, Leonard; Uitti, Ryan J.; Wszolek, Zbigniew K.; Ramos, Eliana Marisa; Grinberg, Lea T.; Tempini, Maria Luisa Gorno; Rosen, Howard J.; Spina, Salvatore; Piguet, Olivier; Grossman, Murray; Trojanowski, John Q.; Keene, C. Dirk; Jin, Lee-Way; Prudlo, Johannes; Geschwind, Daniel H.; Rissman, Robert A.; Cruchaga, Carlos; Ghetti, Bernardino; Halliday, Glenda M.; Beach, Thomas G.; Serrano, Geidy E.; Arzberger, Thomas; Herms, Jochen; Boxer, Adam L.; Honig, Lawrence S.; Vonsattel, Jean P.; Lopez, Oscar L.; Kofler, Julia; White, Charles L.; Gearing, Marla; Glass, Jonathan; Rohrer, Jonathan D.; Irwin, David J.; Lee, Edward B.; Van Deerlin, Vivianna; Castellani, Rudolph; Mesulam, Marsel M.; Tartaglia, Maria C.; Finger, Elizabeth C.; Troakes, Claire; Al-Sarraj, Safa; Dalgard, Clifton L.; Miller, Bruce L.; Seelaar, Harro; Graff-Radford, Neill R.; Boeve, Bradley F.; Mackenzie, Ian RA.; van Swieten, John C.; Seeley, William W.; Sleegers, Kristel; Dickson, Dennis W.; Biernacka, Joanna M.; Rademakers, Rosa 分享 收藏
Biomarker-Based Approach to α-Synucleinopathies: Lessons from Neuropathology 基于生物标志物的 α-突触核蛋白病方法: 神经病理学的教训 Kovacs, Gabor G.; Grinberg, Lea T.; Halliday, Glenda; Alafuzoff, Irina; Dugger, Brittany N.; Murayama, Shigeo; Forrest, Shelley L.; Martinez-Valbuena, Ivan; Tanaka, Hidetomo; Kon, Tomoya; Yoshida, Koji; Jaunmuktane, Zane; Spina, Salvatore; Nelson, Peter T.; Gentleman, Steve; Alegre-Abarrategui, Javier; Serrano, Geidy E.; Paes, Vitor Ribeiro; Takao, Masaki; Wakabayashi, Koichi; Uchihara, Toshiki; Yoshida, Mari; Saito, Yuko; Kofler, Julia; Rodriguez, Roberta Diehl; Gelpi, Ellen; Attems, Johannes; Crary, John F.; Seeley, William W.; Duda, John E.; Keene, C. Dirk; Woulfe, John; Munoz, David; Smith, Colin; Lee, Edward B.; Neumann, Manuela; White, Charles L.; Mckee, Ann C.; Thal, Dietmar R.; Jellinger, Kurt; Ghetti, Bernardino; Mackenzie, Ian R. A.; Dickson, Dennis W.; Beach, Thomas G. 分享 收藏
Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS 血浆细胞外囊泡tau和TDP-43作为FTD和ALS的诊断生物标志物 Chatterjee, Madhurima; Ozdemir, Selcuk; Fritz, Christian; Mobius, Wiebke; Kleineidam, Luca; Mandelkow, Eckhard; Biernat, Jacek; Dogdu, Cem; Peters, Oliver; Cosma, Nicoleta Carmen; Wang, Xiao; Schneider, Luisa-Sophia; Priller, Josef; Spruth, Eike; Kuhn, Andrea A.; Krause, Patricia; Klockgether, Thomas; Vogt, Ina R.; Kimmich, Okka; Spottke, Annika; Hoffmann, Daniel C.; Fliessbach, Klaus; Miklitz, Carolin; McCormick, Cornelia; Weydt, Patrick; Falkenburger, Bjorn; Brandt, Moritz; Guenther, Rene; Dinter, Elisabeth; Wiltfang, Jens; Hansen, Niels; Bahr, Mathias; Zerr, Inga; Floel, Agnes; Nestor, Peter J.; Duzel, Emrah; Glanz, Wenzel; Incesoy, Enise; Burger, Katharina; Janowitz, Daniel; Perneczky, Robert; Rauchmann, Boris S.; Hopfner, Franziska; Wagemann, Olivia; Levin, Johannes; Teipel, Stefan; Kilimann, Ingo; Goerss, Doreen; Prudlo, Johannes; Gasser, Thomas; Brockmann, Kathrin; Mengel, David; Zimmermann, Milan; Synofzik, Matthis; Wilke, Carlo; Selma-Gonzalez, Judit; Turon-Sans, Janina; Santos-Santos, Miguel Angel; Alcolea, Daniel; Rubio-Guerra, Sara; Fortea, Juan; Carbayo, Alvaro; Lleo, Alberto; Rojas-Garcia, Ricardo; Illan-Gala, Ignacio; Wagner, Michael; Frommann, Ingo; Roeske, Sandra; Bertram, Lucas; Heneka, Michael T.; Brosseron, Frederic; Ramirez, Alfredo; Schmid, Matthias; Beschorner, Rudi; Halle, Annett; Herms, Jochen; Neumann, Manuela; Barthelemy, Nicolas R.; Bateman, Randall J.; Rizzu, Patrizia; Heutink, Peter; Dols-Icardo, Oriol; Hoeglinger, Guenter; Hermann, Andreas; Schneider, Anja 分享 收藏
Phenylalanine-tRNA aminoacylation is compromised by ALS/FTD-associated C9orf72 C4G2 repeat RNA Malnar Crnigoj, Mirjana; Cercek, Ursa; Yin, Xiaoke; Ho, Manh Tin; Repic Lampret, Barbka; Neumann, Manuela; Hermann, Andreas; Rouleau, Guy; Suter, Beat; Mayr, Manuel; Rogelj, Boris 分享 收藏
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AAV-mediated expression of a new conformational anti-aggregated α-synuclein antibody prolongs survival in a genetic model of α-synucleinopathies Duechs, Matthias; Blazevic, Dragica; Rechtsteiner, Philipp; Kenny, Cynthia; Lamla, Thorsten; Low, Sarah; Savistchenko, Jimmy; Neumann, Manuela; Melki, Ronald; Schoenberger, Tanja; Stierstorfer, Birgit; Wyatt, David; Igney, Frederik; Ciossek, Thomas 分享 收藏
Limbic-predominant age-related TDP-43 proteinopathy (LATE-NC) is associated with abundant TMEM106B pathology Neumann, Manuela; Perneel, Jolien; Cheung, Simon; van den Broeck, Marleen; Nygaard, Haakon; Hsiung, Ging-Yuek R.; Wynants, Sarah; Heeman, Bavo; Rademakers, Rosa; Mackenzie, Ian R. A. 分享 收藏
GAA-FGF14 ataxia (SCA27B): phenotypic profile, natural history progression and 4-aminopyridine treatment response GAA-FGF14共济失调 (SCA27B): 表型特征，自然史进展和4-氨基吡啶治疗反应 Wilke, Carlo; Pellerin, David; Mengel, David; Traschuetz, Andreas; Danzi, Matt C.; Dicaire, Marie-Josee; Neumann, Manuela; Lerche, Holger; Bender, Benjamin; Houlden, Henry; Zuechner, Stephan; Schoels, Ludger; Brais, Bernard; Synofzik, Matthis 分享 收藏
C9ORF72 knockdown triggers FTD-like symptoms and cell pathology in mice C9ORF72敲低触发小鼠的FTD样症状和细胞病理学 Lopez-Herdoiza, Maria-Belen; Bauche, Stephanie; Wilmet, Baptiste; Le Duigou, Caroline; Roussel, Delphine; Frah, Magali; Beal, Jonas; Devely, Gabin; Boluda, Susana; Frick, Petra; Bouteiller, Delphine; Dussaud, Sebastien; Guillabert, Pierre; Dalle, Carine; Dumont, Magali; Camuzat, Agnes; Saracino, Dario; Barbier, Mathieu; Bruneteau, Gaelle; Ravassard, Phillippe; Neumann, Manuela; Nicole, Sophie; Le Ber, Isabelle; Brice, Alexis; Latouche, Morwena 分享 收藏
Immunotherapy targeting the C-terminal domain of TDP-43 decreases neuropathology and confers neuroprotection in mouse models of ALS/FTD Afroz, Tariq; Chevalier, Elodie; Audrain, Mickael; Dumayne, Christopher; Ziehm, Tamar; Moser, Roger; Egesipe, Anne-Laure; Mottier, Lorene; Ratnam, Monisha; Neumann, Manuela; Havas, Daniel; Ollier, Romain; Piorkowska, Kasia; Chauhan, Mayank; Silva, Alberto B.; Thapa, Samjhana; Stohr, Jan; Bavdek, Andrej; Eligert, Valerie; Adolfsson, Oskar; Nelson, Peter T.; Porta, Silvia; Lee, Virginia M. -Y.; Pfeifer, Andrea; Kosco-Vilbois, Marie; Seredenina, Tamara 分享 收藏
Clinical outcome of biomarker-guided therapies in adult patients with tumors of the nervous system 成年神经系统肿瘤患者的生物标志物指导治疗的临床结果 Renovanz, Mirjam; Kurz, Sylvia C.; Rieger, Johannes; Walter, Bianca; Becker, Hannes; Hille, Hanni; Bombach, Paula; Rieger, David; Grosse, Lucia; Haeusser, Lara; Skardelly, Marco; Merk, Daniel J.; Paulsen, Frank; Hoffmann, Elgin; Gani, Cihan; Neumann, Manuela; Beschorner, Rudi; Riess, Olaf; Roggia, Cristiana; Schroeder, Christopher; Ossowski, Stephan; Armeanu-Ebinger, Sorin; Gschwind, Axel; Biskup, Saskia; Schulze, Martin; Fend, Falko; Singer, Stephan; Zender, Lars; Lengerke, Claudia; Brucker, Sara Yvonne; Engler, Tobias; Forschner, Andrea; Stenzl, Arnulf; Kohlbacher, Oliver; Nahnsen, Sven; Gabernet, Gisela; Fillinger, Sven; Bender, Benjamin; Ernemann, Ulrike; Oener, Oeznur; Beha, Janina; Malek, Holly Sundberg; Moeller, Yvonne; Ruhm, Kristina; Tatagiba, Marcos; Schittenhelm, Jens; Bitzer, Michael; Malek, Nisar; Zips, Daniel; Tabatabai, Ghazaleh 分享 收藏
Accumulation of TMEM106B C-terminal fragments in neurodegenerative disease and aging (Dec, 10.1007/s00401-022-02531-3, 2022) Perneel, Jolien; Neumann, Manuela; Heeman, Bavo; Cheung, Simon; van den Broeck, Marleen; Wynants, Sarah; Baker, Matt; Vicente, Cristina T.; Faura, Julia; Rademakers, Rosa; Mackenzie, Ian R. A. 分享 收藏
Germline findings in patients with advanced malignancies screened with paired blood-tumour testing for personalised treatment approaches Roggia, Cristiana; Armeanu-Ebinger, Sorin; Gschwind, Axel; Seibel-Kelemen, Olga; Hertler, Sonja; Faust, Ulrike; Liebmann, Alexandra; Haack, Tobias B.; Neumann, Manuela; Bonzheim, Irina; Forschner, Andrea; Kopp, Hans-Georg; Herster, Franziska; Hartkopf, Andreas; Bitzer, Michael; Malek, Nisar P.; Brecht, Ines B.; Ruhm, Kristina; Moeller, Yvonne; Loewenheim, Hubert; Ossowski, Stephan; Riess, Olaf H.; Schroeder, Christopher 分享 收藏
Accumulation of TMEM106B C-terminal fragments in neurodegenerative disease and aging Perneel, Jolien; Neumann, Manuela; Heeman, Bavo; Cheung, Simon; van den Broeck, Marleen; Wynants, Sarah; Baker, Matt; Vicente, Cristina T.; Faura, Julia; Rademakers, Rosa; Mackenzie, Ian R. A. 分享 收藏
LATE-NC staging in routine neuropathologic diagnosis: an update Nelson, Peter T.; Lee, Edward B.; Cykowski, Matthew D.; Alafuzoff, Irina; Arfanakis, Konstantinos; Attems, Johannes; Brayne, Carol; Corrada, Maria M.; Dugger, Brittany N.; Flanagan, Margaret E.; Ghetti, Bernardino; Grinberg, Lea T.; Grossman, Murray; Grothe, Michel J.; Halliday, Glenda M.; Hasegawa, Masato; Hokkanen, Suvi R. K.; Hunter, Sally; Jellinger, Kurt; Kawas, Claudia H.; Keene, C. Dirk; Kouri, Naomi; Kovacs, Gabor G.; Leverenz, James B.; Latimer, Caitlin S.; Mackenzie, Ian R.; Mao, Qinwen; McAleese, Kirsty E.; Merrick, Richard; Montine, Thomas J.; Murray, Melissa E.; Myllykangas, Liisa; Nag, Sukriti; Neltner, Janna H.; Newell, Kathy L.; Rissman, Robert A.; Saito, Yuko; Sajjadi, S. Ahmad; Schwetye, Katherine E.; Teich, Andrew F.; Thal, Dietmar R.; Tome, Sandra O.; Troncoso, Juan C.; Wang, Shih-Hsiu J.; White, Charles L., III; Wisniewski, Thomas; Yang, Hyun-Sik; Schneider, Julie A.; Dickson, Dennis W.; Neumann, Manuela 分享 收藏
Common Variants Near ZIC1 and ZIC4 in Autopsy-Confirmed Multiple System Atrophy 尸检证实的多系统萎缩中ZIC1和ZIC4附近的常见变异 Hopfner, Franziska; Tietz, Anja K.; Ruf, Viktoria C.; Ross, Owen A.; Koga, Shunsuke; Dickson, Dennis; Aguzzi, Adriano; Attems, Johannes; Beach, Thomas; Beller, Allison; Cheshire, William P.; van Deerlin, Vivianna; Desplats, Paula; Deuschl, Guenther; Duyckaerts, Charles; Ellinghaus, David; Evsyukov, Valentin; Flanagan, Margaret Ellen; Franke, Andre; Frosch, Matthew P.; Gearing, Marla; Gelpi, Ellen; van Gerpen, Jay A.; Ghetti, Bernardino; Glass, Jonathan D.; Grinberg, Lea T.; Halliday, Glenda; Helbig, Ingo; Hollerhage, Matthias; Huitinga, Inge; Irwin, David John; Keene, Dirk C.; Kovacs, Gabor G.; Lee, Edward B.; Levin, Johannes; Marti, Maria J.; Mackenzie, Ian; McKeith, Ian; Mclean, Catriona; Mollenhauer, Brit; Neumann, Manuela; Newell, Kathy L.; Pantelyat, Alex; Pendziwiat, Manuela; Peters, Annette; Porcel, Laura Molina; Rabano, Alberto; Matej, Radoslav; Rajput, Alex; Rajput, Ali; Reimann, Regina; Scott, William K.; Seeley, William; Selvackadunco, Sashika; Simuni, Tanya; Stadelmann, Christine; Svenningsson, Per; Thomas, Alan; Trenkwalder, Claudia; Troakes, Claire; Trojanowski, John Q.; Uitti, Ryan J.; White, Charles L.; Wszolek, Zbigniew K.; Xie, Tao; Ximelis, Teresa; Yebenes, Justo; Mueller, Ulrich; Schellenberg, Gerard D.; Herms, Jochen; Kuhlenbaumer, Gregor; Hoeglinger, Gunter 分享 收藏
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