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Aortic valve disease augments vesicular microRNA-145-5p to regulate the calcification of valvular interstitial cells via cellular crosstalk Hosen, D. R.; Goody, M. E. D.; Christmann, M. E. D.; Nehl, M. R. S.; Wilhelm-Juengling, D. R.; Abplanalp, D. R.; Iv, D. R. Moore; Uchida, M. R.; Zimmer, D. R.; Bakhtiary, D. R.; Pfeifer, D. R.; Latz, D. R.; Jansen, M. E. D.; Nickenig, D. R. 分享 收藏
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Continued decitabine/all-trans retinoic acid treatment: extended complete remission in an elderly AML patient with multi-hit TP53 lesions and complex-monosomal karyotype Thomas, Johanna; Rehman, Usama-Ur; Bresser, Helena; Grishina, Olga; Pfeifer, Dietmar; Sollier, Etienne; Doehner, Konstanze; Plass, Christoph; Becker, Heiko; Schmoor, Claudia; de Wit, Maike; Luebbert, Michael 分享 收藏
Oncogenic Calreticulin Induces Immune Escape by Stimulating TGFβ Expression and Regulatory T-cell Expansion in the Bone Marrow Microenvironment 致癌钙网蛋白通过刺激骨髓微环境中tgf β 表达和调节性T细胞扩增诱导免疫逃逸 Schmidt, Dominik; Endres, Cornelia; Hoefflin, Rouven; Andrieux, Geoffroy; Zwick, Melissa; Karantzelis, Nikolaos; Staehle, Hans F.; Vinnakota, Janaki Manoja; Duquesne, Sandra; Mozaffari Jovein, Miriam; Pfeifer, Dietmar; Becker, Heiko; Blazar, Bruce R.; Zaehringer, Alexander; Duyster, Justus; Brummer, Tilman; Boerries, Melanie; Baumeister, Julian; Shoumariyeh, Khalid; Li, Juan; Green, Anthony R.; Heidel, Florian H.; Tirosh, Itay; Pahl, Heike L.; Leimkuehler, Nils; Koehler, Natalie; de Toledo, Marcelo A. S.; Koschmieder, Steffen; Zeiser, Robert 分享 收藏
Anti-PD-1 cancer immunotherapy induces central nervous system immune-related adverse events by microglia activation Anti-PD-1肿瘤免疫治疗通过激活小胶质细胞诱导中枢神经系统免疫相关不良事件 Vinnakota, Janaki Manoja; Adams, Rachael C.; Athanassopoulos, Dimitrios; Schmidt, Dominik; Biavasco, Francesca; Zaehringer, Alexander; Erny, Daniel; Schwabenland, Marius; Langenbach, Marlene; Wenger, Valentin; Salie, Henrike; Cook, James; Mossad, Omar; Andrieux, Geoffroy; Dersch, Rick; Rauer, Sebastian; Duquesne, Sandra; Monaco, Gianni; Wolf, Phillipp; Blank, Thomas; Haene, Philipp; Greter, Melanie; Becher, Burkhard; Henneke, Philipp; Pfeifer, Dietmar; Blazar, Bruce R.; Duyster, Justus; Boerries, Melanie; Koehler, Natalie; Chhatbar, Chintan M.; Bengsch, Bertram; Prinz, Marco; Zeiser, Robert 分享 收藏
Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome 靶向小胶质细胞中tgf β 活化激酶-1活化可降低CAR T免疫效应细胞相关神经毒性综合征 Vinnakota, Janaki Manoja; Biavasco, Francesca; Schwabenland, Marius; Chhatbar, Chintan; Adams, Rachael; Erny, Daniel; Duquesne, Sandra; El Khawanky, Nadia; Schmidt, Dominik; Fetsch, Viktor; Zaehringer, Alexander; Salie, Henrike; Athanassopoulos, Dimitrios; Braun, Lukas; Javorniczky, Nora; Ho, Jenny; Kierdorf, Katrin; Marks, Reinhard; Waesch, Ralph; Simonetta, Federico; Andrieux, Geoffroy; Pfeifer, Dietmar; Monaco, Gianni; Capitini, Christian; Fry, Terry; Blank, Thomas; Blazar, Bruce; Wagner, Eva; Theobald, Matthias; Sommer, Clemens; Stelljes, Matthias; Reicherts, Christian; Jeibmann, Astrid; Schittenhelm, Jens; Monoranu, Camelia-Maria; Rosenwald, Andreas; Kortuem, Martin; Rasche, Leo; Einsele, Hermann; Meyer, Philipp; Brumberg, Joachim; Voelkl, Simon; Mackensen, Andreas; Coras, Roland; von Bergwelt-Baildon, Michael; Albert, Nathalie; Bartos, Laura; Brendel, Matthias; Holzgreve, Adrien; Mack, Matthias; Boerries, Melanie; Mackall, Crystal; Duyster, Justus; Henneke, Philipp; Priller, Josef; Koehler, Natalie; Struebing, Felix; Bengsch, Bertram; Ruella, Marco; Subklewe, Marion; von Baumgarten, Louisa; Gill, Saar; Prinz, Marco; Zeiser, Robert 分享 收藏
Nonpreferential but Detrimental Accumulation of Macrophages With Clonal Hematopoiesis-Driver Mutations in Cardiovascular Tissues-Brief Report 心血管组织中具有克隆造血驱动突变的巨噬细胞的非优先但有害的积累-简要报告 Dederichs, Tsai-Sang; Yerdenova, Assel; Horstmann, Hauke; Vico, Tamara Antonela; Nuebling, Simone; Peyronnet, Remi; Pfeifer, Dietmar; von zur Muehlen, Constantin; Heidt, Timo; Wolf, Dennis; Czerny, Martin; Westermann, Dirk; Hilgendorf, Ingo 分享 收藏
Lipocalin-2 expression identifies an intestinal regulatory neutrophil population during acute graft-versus-host disease Czech, Marie; Schneider, Sophia; Peltokangas, Nina; El Khawanky, Nadia; Ghimire, Sakhila; Andrieux, Geoffroy; Huelsduenker, Jan; Krausz, Mate; Proietti, Michele; Braun, Lukas M.; Rueckert, Tamina; Langenbach, Marlene; Schmidt, Dominik; Martin, Ina; Wenger, Valentin; de Vega, Enrique; Haring, Eileen; Pourjam, Mohsen; Pfeifer, Dietmar; Schmitt-Graeff, Annette; Grimbacher, Bodo; Aumann, Konrad; Kircher, Brigitte; Tilg, Herbert; Raffatellu, Manuela; Orberg, Erik Thiele; Haecker, Georg; Duyster, Justus; Koehler, Natalie; Holler, Ernst; Nachbaur, David; Boerries, Melanie; Gerner, Romana R.; Gruen, Dominic; Zeiser, Robert 分享 收藏
ROCK1/2 signaling contributes to corticosteroid-refractory acute graft-versus-host disease Maas-Bauer, Kristina; Stell, Anna-Verena; Yan, Kai-Li; de Vega, Enrique; Vinnakota, Janaki Manoja; Unger, Susanne; Nunez, Nicolas; Norona, Johana; Talvard-Balland, Nana; Kossmann, Stefanie; Schwan, Carsten; Miething, Cornelius; Martens, Uta S.; Shoumariyeh, Khalid; Nestor, Rosa P.; Duquesne, Sandra; Hanke, Kathrin; Rackiewicz, Michal; Hu, Zehan; El Khawanky, Nadia; Taromi, Sanaz; Andrlova, Hana; Faraidun, Hemin; Walter, Stefanie; Pfeifer, Dietmar; Follo, Marie; Waldschmidt, Johannes; Melchinger, Wolfgang; Rassner, Michael; Wehr, Claudia; Schmitt-Graeff, Annette; Halbach, Sebastian; Liao, James; Haecker, Georg; Brummer, Tilman; Dengjel, Joern; Andrieux, Geoffroy; Grosse, Robert; Tugues, Sonia; Blazar, Bruce R.; Becher, Burkhard; Boerries, Melanie; Zeiser, Robert 分享 收藏
Long-term decitabine/retinoic acid maintenance treatment in an elderly sAML patient with high-risk genetics Javorniczky, Nora Rebeka; Grishina, Olga; Hund, Inga; Pantic, Milena; Pfeifer, Dietmar; Schmoor, Claudia; Thomas, Johanna; Duyster, Justus; Becker, Heiko; Luebbert, Michael 分享 收藏
Autonomous B-cell receptor signaling and genetic aberrations in chronic lymphocytic leukemia-phenotype monoclonal B lymphocytosis in siblings of patients with chronic lymphocytic leukemia Quinten, Edwin; Sepulveda-Yanez, Julieta H.; Koning, Marvyn T.; Eken, Janneke A.; Pfeifer, Dietmar; Nteleah, Valeri; de Groen, Ruben A. L.; Saravia, Diego Alvarez; Knijnenburg, Jeroen; Stuivenberg-Bleijswijk, Hedwig E.; Pantic, Milena; Agathangelidis, Andreas; Keppler-Hafkemeyer, Andrea; van Bergen, Cornelis A. M.; Uribe-Paredes, Roberto; Stamatopoulos, Kostas; Vermaat, Joost S. P.; Zirlik, Katja; Navarrete, Marcelo A.; Jumaa, Hassan; Veelken, Hendrik 分享 收藏
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MDM2 Inhibition Enhances Immune Checkpoint Inhibitor Efficacy by Increasing IL15 and MHC Class II Production Langenbach, Marlene; Giesler, Sophie; Richtsfeld, Stefan; Costa-Pereira, Sara; Rindlisbacher, Lukas; Wertheimer, Tobias; Braun, Lukas M.; Andrieux, Geoffroy; Duquesne, Sandra; Pfeifer, Dietmar; Woessner, Nadine M.; Menssen, Hans D.; Taromi, Sanaz; Duyster, Justus; Boerries, Melani; Brummer, Tilman; Blazar, Bruce R.; Minguet, Susana; Turko, Patrick; Levesque, Mitchell P.; Becher, Burkhard; Zeiser, Rober 分享 收藏
In vivo kinetics of early, non-random methylome and transcriptome changes induced by DNA-hypomethylating treatment in primary AML blasts Greve, Gabriele; Andrieux, Geoffroy; Schlosser, Pascal; Blagitko-Dorfs, Nadja; Rehman, Usama-Ur; Ma, Tobias; Pfeifer, Dietmar; Heil, Gerhard; Neubauer, Andreas; Krauter, Juergen; Heuser, Michael; Salih, Helmut R.; Doehner, Konstanze; Doehner, Hartmut; Hackanson, Bjorn; Boerries, Melanie; Luebbert, Michael 分享 收藏
Efficacy of Jak1/2 inhibition in murine myeloproliferative neoplasms is mediated by targeting nonmalignant cells Gorantla, Sivahari Prasad; Rassner, Michael Rassner; Mueller, Tony Andreas; Poggio, Teresa; Crossley, Kirstyn Anne; Denecke, Anna-Lena; Fritsch, Kornelia R.; Andrieux, Geoffroy; Kleinfelder, Helen; Saleem, Shifa Khaja; Gambheer, Sudheer Madan Mohan; Menendez, Irene Gonzalez; Bentrop, Detlef; Trittler, Rainer; Rylova, Svetlana; Pfeifer, Dietmar; Martinez, Leticia Quintanilla; Dierks, Christine; Zeiser, Robert; Illert, Anna Lena; von Bubnoff, Nikolas; Duyster, Justus 分享 收藏
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Cardiomyocyte-specific miR-100 overexpression preserves heart function under pressure overload in mice and diminishes fatty acid uptake as well as ROS production by direct suppression of Nox4 and CD36 Smolka, Christian; Schloesser, Delia; Koentges, Christoph; Tarkhnishvili, Aleksandre; Gorka, Oliver; Pfeifer, Dietmar; Bemtgen, Xavier; Asmussen, Alexander; Gross, Olaf; Diehl, Philipp; Moser, Martin; Bode, Christoph; Bugger, Heiko; Grundmann, Sebastian; Pankratz, Franziska 分享 收藏
MiR-100 overexpression attenuates high fat diet induced weight gain, liver steatosis, hypertriglyceridemia and development of metabolic syndrome in mice Smolka, Christian; Schloesser, Delia; Hohnloser, Catherine; Bemtgen, Xavier; Jaenich, Caterina; Schneider, Laura; Martin, Julien; Pfeifer, Dietmar; Moser, Martin; Hasselblatt, Peter; Bode, Christoph; Grundmann, Sebastian; Pankratz, Franziska 分享 收藏
Therapeutic targeting of endoplasmic reticulum stress in acute graft-versus-host disease Haring, Eileen; Andrieux, Geoffroy; Uhl, Franziska M.; Krausz, Mate; Proietti, Michele; Sauer, Barbara; Esser, Philipp R.; Martin, Stefan F.; Pfeifer, Dietmar; Schmitt-Graeff, Annette; Duyster, Justus; Koehler, Natalie; Grimbacher, Bodo; Boerries, Melanie; Aumann, Konrad; Zeiser, Robert; Apostolova, Petya 分享 收藏
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