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Genetic modeling of ELP1-associated Sonic hedgehog medulloblastoma identifies MDM2 as a selective therapeutic target ELP1相关Sonic hedgehog型髓母细胞瘤的遗传建模识别MDM2为选择性治疗靶点 Ahmad, Shiekh Tanveer; Li, Yiran; Garcia-Lopez, Jesus; Gudenas, Brian; Hadley, Jennifer; Paul, Leena; Wu, Stephanie; Refaat, Alaa; Kojic, Marija; Batts, Melissa; Soliman, Taha; Pitre, Aaron; Arnskotter, Frederik; Zindy, Frederique; Jones, Alun; Twarog, Nathaniel; Mayasundari, Anand; Bianski, Brandon; Tinkle, Christopher; Shirinifard, Abbas; Janke, Laura; Lu, Meifen; Lewis, Sara; Onar-Thomas, Arzu; Pfister, Stefan; Gajjar, Amar; Baker, Suzanne; Roussel, Martine; Rankovic, Zoran; Robinson, Giles; Orr, Brent; Wainwright, Brandon; Shelat, Anang; Waszak, Sebastian; Kutscher, Lena; Lin, Hong; Northcott, Paul 分享 收藏
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GERMLINEELP1 DEFICIENCY SENSITIZES CEREBELLAR GRANULE NEURON PROGENITORS TO SHH MEDULLOBLASTOMA Tanveer Ahmad, Shiekh; Garcia-Lopez, Jesus; Li, Yiran; Hadley, Jennifer; Paul, Leena; Gudenas, Brian; Batts, Melissa; Soliman, Taha; Pitre, Aaron; Kojic, Marija; Manz, Frederik; Zindy, Frederique; Jones, Alun; Mayasundari, Anand; Bianski, Brandon; Tinkle, Christopher; Shirinifard, Abbas; Janke, Laura Janke; Lu, Meifen; Onar-Thomas, Arzu; Pfister, Stefan; Gajjar, Amar; Baker, Suzanne; Roussel, Martine; Rankovic, Zoran; Robinson, Giles; Orr, Brent; Wainwright, Brandon; Kutscher, Lena; Waszak, Sebastian; Lin, Hong; Northcott, Paul 分享 收藏
A fluorogenic complementation tool kit for interrogating lipid droplet-organelle interaction Li, Xiao; Gamuyao, Rico; Wu, Ming-Lun; Cho, Woo Jung; King, Sharon V.; Petersen, R. A.; Stabley, Daniel R.; Lindow, Caleb; Climer, Leslie K.; Shirinifard, Abbas; Ferrara, Francesca; Throm, Robert E.; Robinson, Camenzind G.; Zhou, Yiwang; Carisey, Alexandre F.; Tebo, Alison G.; Chang, Chi-Lun 分享 收藏
GERMLINEELP1 DEFICIENCY SENSITIZES CEREBELLAR GRANULE NEURON PROGENITORS TO SHH MEDULLOBLASTOMA Ahmad, Shiekh Tanveer; Garcia-Lopez, Jesus; Li, Yiran; Gudenas, Brian; Hadley, Jennifer; Paul, Leena; Batts, Melissa; Soliman, Taha; Kojic, Marija; Pitre, Aaron; Manz, Frederik; Zindy, Frederique; Jones, Alun; Mayasundari, Anand; Bianski, Brandon; Tinkle, Christopher; Shirinifard, Abbas; Janke, Laura; Lu, Meifen; Pfister, Stefan M.; Gajjar, Amar; Baker, Suzanne J.; Roussel, Martine F.; Rankovic, Zoran; Waszak, Sebastian M.; Robinson, Giles W.; Orr, Brent A.; Wainwright, Brandon; Kutscher, Lena M.; Lin, Hong; Northcott, Paul A. 分享 收藏
ZFTA FUSION ONCOPROTEINS DRIVE ONCOGENESIS THROUGH ASSEMBLY OF BIOMOLECULAR CONDENSATES Varadharajan, Srinidhi; Arabzade, Amir; Shirnekhi, Hazheen K.; Ippagunta, Siri; Laboe, Nic; Gee, David; Emanus, Erik; Kardian, Alisha; Phillips, Aaron H.; Tripathi, Swarnendu; Shirinifard, Abbas; Petersen, Becky; King, Sharon; Stabley, Daniel; Pitre, Aaron; Campbell, George; Park, Cheon-Gil; Durbin, Adam D.; Qi, Jun; Bertrand, Kelsey; Taylor, Michael D.; Northcott, Paul A.; Deneen, Benjamin; Ansari, Aseem Z.; Kriwacki, Richard W.; Mack, Stephen C. 分享 收藏
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An adaptive stress response that confers cellular resilience to decreased ubiquitination Hunt, Liam C.; Pagala, Vishwajeeth; Stephan, Anna; Xie, Boer; Kodali, Kiran; Kavdia, Kanisha; Wang, Yong-Dong; Shirinifard, Abbas; Curley, Michelle; Graca, Flavia A.; Fu, Yingxue; Poudel, Suresh; Li, Yuxin; Wang, Xusheng; Tan, Haiyan; Peng, Junmin; Demontis, Fabio 分享 收藏
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Ontology guided navigation of somatic variants, mutational signatures, gene expression and histology images for pediatric cancer Gout, Alexander M.; Sandor, Stephanie; Rahbarinia, Delaram; Sunny, Jobin; Madson, James; Vacaroiu, Lucian; Yang, Wentao; Lansdell, Ben; Macias, Michael; Brady, Samuel W.; Finkelstein, David; Pastor, Victor; Benton, Kevin; Frantz, Andrew; Wilkinson, Mark R.; Cline, Cynthia; Orr, Brent A.; Shirinifard, Abbas; Stewart, Elizabeth; Rusch, Michael; Zhou, Xin; Dyer, Michael; Wheeler, David A.; McLeod, Clay; Zhang, Jinghui 分享 收藏
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Matricellular Protein WISP2 Is an Endogenous Inhibitor of Collagen Linearization and Cancer Metastasis Janjanam, Jagadeesh; Pano, Glendin; Wang, Ruishan; Minden-Birkenmaier, Benjamin A.; Breeze-Jones, Hannah; Baker, Eleanor; Garcin, Cecile; Clayton, Georgia; Shirinifard, Abbas; Zaske, Ana Maria; Finkelstein, David; Labelle, Myriam 分享 收藏
Oxygen Tension and the VHL-Hif1α Pathway Determine Onset of Neuronal Polarization and Cerebellar Germinal Zone Exit Kullmann, Jan A.; Trivedi, Niraj; Howell, Danielle; Laumonnerie, Christophe; Nguyen, Vien; Banerje, Shalini S.; Stabley, Daniel R.; Shirinifard, Abbas; Rowitch, David H.; Solecki, David J. 分享 收藏
Deep multiomics profiling of brain tumors identifies signaling networks downstream of cancer driver genes Wang, Hong; Diaz, Alexander K.; Shaw, Timothy I.; Li, Yuxin; Niu, Mingming; Cho, Ji-Hoon; Paugh, Barbara S.; Zhang, Yang; Sifford, Jeffrey; Bai, Bing; Wu, Zhiping; Tan, Haiyan; Zhou, Suiping; Hover, Laura D.; Tillman, Heather S.; Shirinifard, Abbas; Thiagarajan, Suresh; Sablauer, Andras; Pagala, Vishwajeeth; High, Anthony A.; Wang, Xusheng; Li, Chunliang; Baker, Suzanne J.; Peng, Junmin 分享 收藏
The tumor cell-secreted matricellular protein WISP1 drives pro-metastatic collagen linearization Jia, Hong; Janjanam, Jagadeesh; Wu, Sharon C.; Wang, Ruishan; Pano, Glendin; Celestine, Marina; Martinot, Ophelie; Breeze-Jones, Hannah; Clayton, Georgia; Garcin, Cecile; Shirinifard, Abbas; Zaske, Ana Maria; Finkelstein, David; Labelle, Myriam 分享 收藏
Circadian gene variants and the skeletal muscle circadian clock contribute to the evolutionary divergence in longevity across Drosophila populations Hunt, Liam C.; Jiao, Jianqin; Wang, Yong-Dong; Finkelstein, David; Rao, Deepti; Curley, Michelle; Robles-Murguia, Maricela; Shirinifard, Abbas; Pagala, Vishwajeeth R.; Peng, Junmin; Fan, Yiping; Demontis, Fabio 分享 收藏
Retinal Cell Type DNA Methylation and Histone Modifications Predict Reprogramming Efficiency and Retinogenesis in 3D Organoid Cultures Wang, Lu; Hiler, Daniel; Xu, Beisi; AlDiri, Issam; Chen, Xiang; Zhou, Xin; Griffiths, Lyra; Valentine, Marc; Shirinifard, Abbas; Sablauer, Andras; Thiagarajan, Suresh; Barabas, Marie-Elizabeth; Zhang, Jiakun; Johnson, Dianna; Frase, Sharon; Dyer, Michael A. 分享 收藏
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