Kazuto Nakada - Publications, H-index & Citations

Kazuto Nakada

Institute of Life and Environmental Sciences

37H指数

149论文数

7.2K被引数

收录论文 57

发表时间

Cross-species urinary metabolomics identifies 2-hydroxyisovalerate as a candidate biomarker for mtDNA-based disorders 跨物种尿液代谢组学鉴定2-羟基异戊酸为mtDNA相关疾病的候选生物标志物

Metabolomics

IF3.3

2026-08-20

OAAI

Marianne Venter; Karin Terburgh; Jeremie Z. Lindeque; Emi Ogasawara; Mirian C. H. Janssen; Jan A. M. Smeitink; Kazuto Nakada; Roan Louw

Comparative analysis of muscle pathologies and metabolic signaling in mouse models of mitochondrial dysfunction 小鼠线粒体功能障碍模型中肌肉病理学与代谢信号的比较分析

Scientific Reports

IF3.9

2026-04-16

OAAI

Hiroaki Tamashiro; Kaori Ishikawa; Kazuto Nakada

Mitochondrial vulnerability underlies myocarditis from COVID-19 mRNA vaccine COVID-19 mRNA疫苗所致心肌炎的发病机制与线粒体易损性相关

Nature Communications

IF15.7

2026-04-01

OAAI

Go Mori; Masayoshi Yamamoto; Kaori Ishikawa; Hiroaki Tamashiro; Hayate Suzuki; Seiya Mizuno; Kazuto Nakada; Atsushi Kawaguchi

Mitochondria-Dependent Metabolic Reprogramming Enhances Myofibroblast Differentiation and Aggravates Bleomycin-Induced Pulmonary Fibrosis 线粒体依赖性代谢重编程增强肌成纤维细胞分化并加重博莱霉素诱导的肺纤维化

Cells

IF5.2

2026-03-01

OAAI

Yazaki, Kai; Matsuno, Yosuke; Yabuuchi, Yuki; Matsumura, Sosuke; Kuramoto, Kenya; Yoshida, Kazufumi; Matsuyama, Masashi; Kiwamoto, Takumi; Morishima, Yuko; Ishii, Yukio; Ishikawa, Kaori; Nakada, Kazuto; Hizawa, Nobuyuki

Effect of Denervation on Skeletal Muscle Mitochondria in Heterozygous mtDNA Mutator Mice 去神经支配对杂合mtDNA突变小鼠骨骼肌线粒体的影响

FASEB BioAdvances

IF2

2026-02-04

OAAI

Shirai, Takanaga; Hanakita, Hideto; Takeda, Kohei; Kitaoka, Yu; Ishikawa, Kaori; Nakada, Kazuto; Takemasa, Tohru

Mitochondrial Respiratory Dysfunction Is Not Correlated With Mitochondrial Genotype in Premature Aging Mice 线粒体呼吸功能障碍与早衰小鼠的线粒体基因型无相关性

AGING CELL

IF7.1

2025-05-02

OAAI

Tamashiro, H; Ishikawa, K; Sadotomo, K; Ogasawara, E; Nakada, K

Endurance swimming exacerbates mitochondrial myopathy in mice with high mtDNA deletions

Mitochondrion

IF4.5

2025-03-01

OAAI

Hanada, Sho; Ishikawa, Kaori; Shirai, Takanaga; Takemasa, Tohru; Nakada, Kazuto

TEFM facilitates transition from RNA synthesis to DNA synthesis at H-strand replication origin of mtDNA

COMMUNICATIONS BIOLOGY

IF5.1

2025-02-08

OAAI

Matsuda, Shigeru; Nakayama, Masunari; Do, Yura; Ishiuchi, Takashi; Yagi, Mikako; Wanrooij, Sjoerd; Nakada, Kazuto; Wei, Fan-Yan; Ichiyanagi, Kenji; Sasaki, Hiroyuki; Kang, Dongchon; Yasukawa, Takehiro

Accumulation of mitochondrial DNA with a point mutation in tRNALeu(UUR) gene induces brain dysfunction in mice

PHARMACOLOGICAL RESEARCH

IF10.5

2024-10-01

OAAI

Ishikawa, Kaori; Miyata, Daiki; Hattori, Satoko; Tani, Haruna; Kuriyama, Takayoshi; Wei, Fan-Yan; Miyakawa, Tsuyoshi; Nakada, Kazuto

Large-scale animal model study uncovers altered brain pH and lactate levels as a transdiagnostic endophenotype of neuropsychiatric disorders involving cognitive impairment 大规模动物模型研究发现大脑pH和乳酸水平的改变是涉及认知障碍的神经精神障碍的诊断内表型

ELIFE

IF0

2024-03-26

OAAI

Hagihara, Hideo; Shoji, Hirotaka; Hattori, Satoko; Sala, Giovanni; Takamiya, Yoshihiro; Tanaka, Mika; Ihara, Masafumi; Shibutani, Mihiro; Hatada, Izuho; Hori, Kei; Hoshino, Mikio; Nakao, Akito; Mori, Yasuo; Okabe, Shigeo; Matsushita, Masayuki; Urbach, Anja; Katayama, Yuta; Matsumoto, Akinobu; Nakayama, Keiichi I.; Katori, Shota; Sato, Takuya; Iwasato, Takuji; Nakamura, Haruko; Goshima, Yoshio; Raveau, Matthieu; Tatsukawa, Tetsuya; Yamakawa, Kazuhiro; Takahashi, Noriko; Kasai, Haruo; Inazawa, Johji; Nobuhisa, Ikuo; Kagawa, Tetsushi; Taga, Tetsuya; Darwish, Mohamed; Nishizono, Hirofumi; Takao, Keizo; Sapkota, Kiran; Nakazawa, Kazutoshi; Takagi, Tsuyoshi; Fujisawa, Haruki; Sugimura, Yoshihisa; Yamanishi, Kyosuke; Rajagopal, Lakshmi; Hannah, Nanette Deneen; Meltzer, Herbert Y.; Yamamoto, Tohru; Wakatsuki, Shuji; Araki, Toshiyuki; Tabuchi, Katsuhiko; Numakawa, Tadahiro; Kunugi, Hiroshi; Huang, Freesia L.; Hayata-Takano, Atsuko; Hashimoto, Hitoshi; Tamada, Kota; Takumi, Toru; Kasahara, Takaoki; Kato, Tadafumi; Graef, Isabella A.; Crabtree, Gerald R.; Asaoka, Nozomi; Hatakama, Hikari; Kaneko, Shuji; Kohno, Takao; Hattori, Mitsuharu; Hoshiba, Yoshio; Miyake, Ryuhei; Obi-Nagata, Kisho; Hayashi-Takagi, Akiko; Becker, Lea J.; Yalcin, Ipek; Hagino, Yoko; Kotajima-Murakami, Hiroko; Moriya, Yuki; Ikeda, Kazutaka; Kim, Hyopil; Kaang, Bong-Kiun; Otabi, Hikari; Yoshida, Yuta; Toyoda, Atsushi; Komiyama, Noboru H.; Grant, Seth G. N.; Ida-Eto, Michiru; Narita, Masaaki; Matsumoto, Ken-Ichi; Okuda-Ashitaka, Emiko; Ohmori, Iori; Shimada, Tadayuki; Yamagata, Kanato; Ageta, Hiroshi; Tsuchida, Kunihiro; Inokuchi, Kaoru; Sassa, Takayuki; Kihara, Akio; Fukasawa, Motoaki; Usuda, Nobuteru; Katano, Tayo; Tanaka, Teruyuki; Yoshihara, Yoshihiro; Igarashi, Michihiro; Hayashi, Takashi; Ishikawa, Kaori; Yamamoto, Satoshi; Nishimura, Naoya; Nakada, Kazuto; Hirotsune, Shinji; Egawa, Kiyoshi; Higashisaka, Kazuma; Tsutsumi, Yasuo; Nishihara, Shoko; Sugo, Noriyuki; Yagi, Takeshi; Ueno, Naoto; Yamamoto, Tomomi; Kubo, Yoshihiro; Ohashi, Rie; Shiina, Nobuyuki; Shimizu, Kimiko; Higo-Yamamoto, Sayaka; Oishi, Katsutaka; Mori, Hisashi; Furuse, Tamio; Tamura, Masaru; Shirakawa, Hisashi; Sato, Daiki X.; Inoue, Yukiko U.; Inoue, Takayoshi; Komine, Yuriko; Yamamori, Tetsuo; Sakimura, Kenji; Miyakawa, Tsuyoshi

Mammalian copper chaperone Cox17p has an essential role in activation of cytochrome c oxidase and embryonic development

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-27

118

OAAI

Takahashi, Y; Kako, K; Kashiwabara, S; Takehara, A; Inada, Y; Arai, H; Nakada, K; Kodama, H; Hayashi, J; Baba, T; Munekata, E

Dynamics of Mitochondrial DNA Nucleoids Regulated by Mitochondrial Fission Is Essential for Maintenance of Homogeneously Active Mitochondria during Neonatal Heart Development

MOLECULAR AND CELLULAR BIOLOGY

IF2.7

2023-03-20

149

OAAI

Ishihara, Takaya; Ban-Ishihara, Reiko; Maeda, Maki; Matsunaga, Yui; Ichimura, Ayaka; Kyogoku, Sachiko; Aoki, Hiroki; Katada, Shun; Nakada, Kazuto; Nomura, Masatoshi; Mizushima, Noboru; Mihara, Katsuyoshi; Ishihara, Naotada

Pearson syndrome-like anemia induced by accumulation of mutant mtDNA and anemia with imbalanced white blood cell lineages induced by Drp1 deletion in a murine model

PHARMACOLOGICAL RESEARCH

IF10.5

2022-11-01

OAAI

Ishikawa, Kaori; Honma, Yo; Yoshimi, Ayami; Katada, Shun; Ishihara, Takaya; Ishihara, Naotada; Nakada, Kazuto

Aberrant RNA processing contributes to the pathogenesis of mitochondrial diseases in trans-mitochondrial mouse model carrying mitochondrial tRNALeu(UUR) with a pathogenic A2748G mutation

NUCLEIC ACIDS RESEARCH

IF13.1

2022-08-24

OAAI

Tani, Haruna; Ishikawa, Kaori; Tamashiro, Hiroaki; Ogasawara, Emi; Yasukawa, Takehiro; Matsuda, Shigeru; Shimizu, Akinori; Kang, Dongchon; Hayashi, Jun-Ichi; Wei, Fan-Yan; Nakada, Kazuto

Mitochondrial DNA mutations are involved in the acquisition of cisplatin resistance in human lung cancer A549 cells

ONCOLOGY REPORTS

IF3.9

2021-12-20

OAAI

Horibe, Sayo; Ishikawa, Kaori; Nakada, Kazuto; Wake, Masaki; Takeda, Norihiko; Tanaka, Toru; Kawauchi, Shoji; Sasaki, Naoto; Rikitake, Yoshiyuki

A high mutation load of m.14597A>G in MT-ND6 causes Leigh syndrome MT-ND6 m.14597A>G的高突变负荷导致Leigh综合征

SCIENTIFIC REPORTS

IF3.9

2021-05-27

OAAI

Kishita, Yoshihito; Ishikawa, Kaori; Nakada, Kazuto; Hayashi, Jun-Ichi; Fushimi, Takuya; Shimura, Masaru; Kohda, Masakazu; Ohtake, Akira; Murayama, Kei; Okazaki, Yasushi

Neuronal degeneration and cognitive impairment can be prevented via the normalization of mitochondrial dynamics

PHARMACOLOGICAL RESEARCH

IF10.5

2021-01-01

PREAI

Ishikawa, Kaori; Yamamoto, Satoshi; Hattori, Satoko; Nishimura, Naoya; Matsumoto, Hirokazu; Miyakawa, Tsuyoshi; Nakada, Kazuto

Distal control of mitochondrial biogenesis and respiratory activity by extracellular lactate caused by large-scale deletion of mitochondrial DNA

PHARMACOLOGICAL RESEARCH

IF10.5

2020-10-01

OAAI

Ogasawara, Emi; Nakada, Kazuto; Ishihara, Naotada