Gerard D. Schellenberg - Publications, H-index & Citations

Gerard D. Schellenberg

Department of Pathology and Laboratory Medicine

92H指数

491论文数

4.3W被引数

收录论文 150

发表时间

Domain mapping of disease mutations reveals pathogenic SORL1 variants in Alzheimer’s disease 疾病突变的结构域定位揭示了阿尔茨海默氏病的致病性SORL1变体

Molecular Neurodegeneration

IF17.5

2025-12-01

OAAI

Olav M. Andersen; Matthijs W. J. de Waal; Giulia Monti; Niccolo Tesi; Anne Mette G. Jensen; Christa de Geus; Rosalina van Spaendonk; Maartje Vogel; Shahzad Ahmad; Najaf Amin; Philippe Amouyel; Gary W. Beecham; Céline Bellenguez; Claudine Berr; Joshua C. Bis; Anne Boland; Paola Bossù; Femke Bouwman; Jose Bras; Camille Charbonnier; Jordi Clarimon; Carlos Cruchaga; Antonio Daniele; Jean-François Dartigues; Stéphanie Debette; Jean-François Deleuze; Nicola Denning; Anita L. DeStefano; Oriol Dols-Icardo; Cornelia M. van Duijn; Lindsay A. Farrer; Maria Victoria Fernández; Wiesje M. van der Flier; Nick C. Fox; Daniela Galimberti; Emmanuelle Genin; Johan J. P. Gille; Benjamin Grenier-Boley; Detelina Grozeva; Yann Le Guen; Rita Guerreiro; Jonathan L. Haines; Clive Holmes; Holger Hummerich; M. Arfan Ikram; M. Kamran Ikram; Amit Kawalia; Robert Kraaij; Jean-Charles Lambert; Marc Lathrop; Afina W. Lemstra; Alberto Lleó; Richard M. Myers; Marcel M. A. M. Mannens; Rachel Marshall; Eden R. Martin; Carlo Masullo; Richard Mayeux; Simon Mead; Patrizia Mecocci; Alun Meggy; Merel O. Mol; Benedetta Nacmias; Adam C. Naj; Valerio Napolioni; J. Nicholas Cochran; Gaël Nicolas; Florence Pasquier; Pau Pastor; Margaret A. Pericak-Vance; Yolande A. L. Pijnenburg; Fabrizio Piras; Olivier Quenez; Alfredo Ramirez; Rachel Raybould; Richard Redon; Marcel J. T. Reinders; Anne-Claire Richard; Steffi G. Riedel-Heller; Fernando Rivadeneira; Jeroen G. J. van Rooij; Stéphane Rousseau; Natalie S. Ryan; Pascual Sanchez-Juan; Gerard D. Schellenberg; Philip Scheltens; Jonathan M. Schott; Sudha Seshadri; Daoud Sie; Rebecca Sims; Erik A. Sistermans; Sandro Sorbi; John C. van Swieten; Betty Tijms; André G. Uitterlinden; Pieter Jelle Visser; Michael Wagner; David Wallon; Li-San Wang; Julie Williams; Jennifer S. Yokoyama; Aline Zarea; Sven J. van der Lee; Johan G. Olsen; Marc Hulsman; Henne Holstege

Genome-wide association studies of TDP-43 proteinopathy and hippocampal sclerosis reveal shared genetic associations with APOE and TMEM106B 全基因组关联研究揭示了TDP-43蛋白病和海马硬化的共享遗传关联，涉及APOE和TMEM106B。

Alzheimer's & Dementia

IF11.1

2025-11-10

OAAI

Dana Godrich; Jeremy Pasteris; Eden R. Martin; Brian Kunkle; Adam C. Naj; Kara Hamilton; Hui Wang; Wan-Ping Lee; Logan Dumitrescu; Timothy J. Hohman; Richard Mayeux; Eric B. Larson; Paul K. Crane; C. Dirk Keene; Caitlin Latimer; Shubhabrata Mukherjee; Julia Kofler; M. Ilyas Kamboh; David A. Bennett; Laura Molina-Porcel; Gerard Schellenberg; Margaret A. Pericak-Vance; Michael Cuccaro; William K. Scott; Tatjana Rundek; Walter Kukull; Thomas Montine; Gary W. Beecham; the Alzheimer's Disease Genetics Consortium (ADGC)

2988Multi-omic derived cell-type specific Alzheimer disease polygenic risk scores 2988 多组学衍生的细胞类型特异性阿尔茨海默病多基因风险评分

Neurobiology of Aging

IF3.5

2025-07-16

OAAI

Nicholas O’Neill; Nuzulul Kurniansyah; Congcong Zhu; Oluwatosin A. Olayinka; Richard Mayeux; Jonathan L. Haines; Margaret A. Pericak-Vance; Li-San Wang; Gerard C. Schellenberg; Lindsay A. Farrer; Xiaoling Zhang

Examining the Performance of Polygenic Risk Scores for Alzheimer Disease Within and Across Populations Using k-Fold Cross-Validation

NEUROLOGY-GENETICS

IF3.7

2024-12-01

OAAI

Osterman, Michael D.; Song, Yeunjoo E.; Lynn, Audrey; Miskimen, Kristy; Wheeler, Nicholas R.; Bartlett, Jacquelaine; Farrer, Lindsay A.; Schellenberg, Gerard D.; Martin, Eden R.; Pericak-Vance, Margaret A.; Bush, William S.; Haines, Jonathan L.

Cerebral amyloid angiopathy impacts neurofibrillary tangle burden and cognition

BRAIN COMMUNICATIONS

IF4.5

2024-11-22

OAAI

Godrich, Dana; Pasteris, Jeremy; Martin, Eden R.; Rundek, Tatjana; Schellenberg, Gerard; Foroud, Tatiana; Vance, Jeffery M.; Pericak-Vance, Margaret A.; Cuccaro, Michael L.; Scott, William K.; Kukull, Walter; Montine, Thomas J.; Beecham, Gary W.

Extended genome-wide association study employing the African genome resources panel identifies novel susceptibility loci for Alzheimer's disease in individuals of African ancestry 采用非洲基因组资源小组的扩展全基因组关联研究确定了非洲血统个体中阿尔茨海默病的新易感位点

ALZHEIMERS & DEMENTIA

IF11.1

2024-07-03

OAAI

Ray, Nicholas R.; Kunkle, Brian W.; Hamilton-Nelson, Kara; Kurup, Jiji T.; Rajabli, Farid; Qiao, Min; Vardarajan, Badri N.; Cosacak, Mehmet I.; Kizil, Caghan; Jean-Francois, Melissa; Cuccaro, Michael; Reyes-Dumeyer, Dolly; Cantwell, Laura; Kuzma, Amanda; Vance, Jeffery M.; Gao, Sujuan; Hendrie, Hugh C.; Baiyewu, Olusegun; Ogunniyi, Adesola; Akinyemi, Rufus O.; Lee, Wan-Ping; Martin, Eden R.; Wang, Li-San; Beecham, Gary W.; Bush, William S.; Xu, Wanying; Jin, Fulai; Wang, Liyong; Farrer, Lindsay A.; Haines, Jonathan L.; Byrd, Goldie S.; Schellenberg, Gerard D.; Mayeux, Richard; Pericak-Vance, Margaret A.; Reitz, Christiane

MSUT2 regulates tau spreading via adenosinergic signaling mediated ASAP1 pathway in neurons MSUT2通过腺苷酸信号介导的ASAP1通路调节神经元tau扩散

ACTA NEUROPATHOLOGICA

IF9.3

2024-03-12

OAAI

Xu, Hong; Qiu, Qi; Hu, Peng; Hoxha, Kevt'her; Jang, Elliot; O'Reilly, Mia; Kim, Christopher; He, Zhuohao; Marotta, Nicholas; Changolkar, Lakshmi; Zhang, Bin; Wu, Hao; Schellenberg, Gerard D.; Kraemer, Brian; Luk, Kelvin C.; Lee, Edward B.; Trojanowski, John Q.; Brunden, Kurt R.; Lee, Virginia M. -Y.

A comparative study of structural variant calling in WGS from Alzheimer's disease families

LIFE SCIENCE ALLIANCE

IF2.9

2024-02-28

OAAI

Malamon, John S.; Farrell, John J.; Xia, Li Charlie; Dombroski, Beth A.; Das, Rueben G.; Way, Jessica; Kuzma, Amanda B.; Valladares, Otto; Leung, Yuk Yee; Scanlon, Allison J.; Lopez, Irving Antonio Barrera; Brehony, Jack; Worley, Kim C.; Zhang, Nancy R.; Wang, Li-San; Farrer, Lindsay A.; Schellenberg, Gerard D.; Lee, Wan-Ping; Vardarajan, Badri N.

Asian Cohort for Alzheimer's Disease (ACAD) pilot study on genetic and non-genetic risk factors for Alzheimer's disease among Asian Americans and Canadians 亚洲阿尔茨海默病队列 (ACAD) 亚裔美国人和加拿大人阿尔茨海默病遗传和非遗传危险因素的初步研究

ALZHEIMERS & DEMENTIA

IF11.1

2024-01-12

OAAI

Ho, Pei-Chuan; Yu, Wai Haung; Tee, Boon Lead; Lee, Wan-Ping; Li, Clara; Gu, Yian; Yokoyama, Jennifer S.; Reyes-Dumeyer, Dolly; Choi, Yun-Beom; Yang, Hyun-Sik; Vardarajan, Badri N.; Tzuang, Marian; Lieu, Kevin; Lu, Anna; Faber, Kelley M.; Potter, Zoe D.; Revta, Carolyn; Kirsch, Maureen; Mccallum, Jake; Mei, Diana; Booth, Briana; Cantwell, Laura B.; Chen, Fangcong; Chou, Sephera; Clark, Dewi; Deng, Michelle; Hong, Ting Hei; Hwang, Ling-Jen; Jiang, Lilly; Joo, Yoonmee; Kang, Younhee; Kim, Ellen S.; Kim, Hoowon; Kim, Kyungmin; Kuzma, Amanda B.; Lam, Eleanor; Lanata, Serggio C.; Lee, Kunho; Li, Donghe; Li, Mingyao; Li, Xiang; Liu, Chia-Lun; Liu, Collin; Liu, Linghsi; Lupo, Jody-Lynn; Nguyen, Khai; Pfleuger, Shannon E.; Qian, James; Qian, Winnie; Ramirez, Veronica; Russ, Kristen A.; Seo, Eun Hyun; Song, Yeunjoo E.; Tartaglia, Maria Carmela; Tian, Lu; Torres, Mina; Vo, Namkhue; Wong, Ellen C.; Xie, Yuan; Yau, Eugene B.; Yi, Isabelle; Yu, Victoria; Zeng, Xiaoyi; St George-Hyslop, Peter; Au, Rhoda; Schellenberg, Gerard D.; Dage, Jeffrey L.; Varma, Rohit; Hsiung, Ging-Yuek R.; Rosen, Howard; Henderson, Victor W.; Foroud, Tatiana; Kukull, Walter A.; Peavy, Guerry M.; Lee, Haeok; Feldman, Howard H.; Mayeux, Richard; Chui, Helena; Jun, Gyungah R.; Ta Park, Van M.; Chow, Tiffany W.; Wang, Li-San

Report of the APOE4 National Institute on Aging/Alzheimer Disease Sequencing Project Consortium Working Group: Reducing APOE4 in Carriers is a Therapeutic Goal for Alzheimer's Disease APOE4美国国立老化研究所/阿尔茨海默病测序项目联盟工作组报告：降低携带者体内的APOE4水平是阿尔茨海默病的治疗目标

ANNALS OF NEUROLOGY

IF7.7

2024-01-05

OAAI

Vance, Jeffery M.; Farrer, Lindsay A.; Huang, Yadong; Cruchaga, Carlos; Hyman, Bradley T.; Pericak-Vance, Margaret A.; Goate, Alison M.; Greicius, Michael D.; Griswold, Anthony J.; Haines, Jonathan L.; Julia, T. C. W.; Schellenberg, Gerard D.; Tsai, Li-Huei; Herz, Joachim; Holtzman, David M.

Sex-specific genetic architecture of late-life memory performance 晚年记忆表现的性别特异性遗传结构

ALZHEIMERS & DEMENTIA

IF11.1

2023-11-20

OAAI

Eissman, Jaclyn M.; Archer, Derek B.; Mukherjee, Shubhabrata; Lee, Michael L.; Choi, Seo-Eun; Scollard, Phoebe; Trittschuh, Emily H.; Mez, Jesse B.; Bush, William S.; Kunkle, Brian W.; Naj, Adam C.; Gifford, Katherine A.; Cuccaro, Michael L.; Cruchaga, Carlos; Pericak-Vance, Margaret A.; Farrer, Lindsay A.; Wang, Li-San; Schellenberg, Gerard D.; Mayeux, Richard P.; Haines, Jonathan L.; Jefferson, Angela L.; Kukull, Walter A.; Keene, C. Dirk; Saykin, Andrew J.; Thompson, Paul M.; Martin, Eden R.; Bennett, David A.; Barnes, Lisa L.; Schneider, Julie A.; Crane, Paul K.; Hohman, Timothy J.; Dumitrescu, Logan

NIAGADS Alzheimer's GenomicsDB: A resource for exploring Alzheimer's disease genetic and genomic knowledge NIAGADS Alzheimer's GenomicsDB: 探索阿尔茨海默病遗传和基因组知识的资源

ALZHEIMERS & DEMENTIA

IF11.1

2023-10-26

OAAI

Greenfest-Allen, Emily; Valladares, Otto; Kuksa, Pavel P.; Gangadharan, Prabhakaran; Lee, Wan-Ping; Cifello, Jeffrey; Katanic, Zivadin; Kuzma, Amanda B.; Wheeler, Nicholas; Bush, William S.; Leung, Yuk Yee; Schellenberg, Gerard; Stoeckert, Christian J., Jr.; Wang, Li-San

DNA from multiple viral species is associated with Alzheimer's disease risk

ALZHEIMERS & DEMENTIA

IF11.1

2023-08-14

OAAI

Tejeda, Marlene; Farrell, John; Zhu, Congcong; Wetzler, Lee; Lunetta, Kathryn L.; Bush, William S.; Martin, Eden R.; Wang, Li-San; Schellenberg, Gerard D.; Pericak-Vance, Margaret A.; Haines, Jonathan L.; Farrer, Lindsay A.; Sherva, Richard

The Early-Onset Alzheimer's Disease Whole-Genome Sequencing Project: Study design and methodology

ALZHEIMERS & DEMENTIA

IF11.1

2023-06-30

OAAI

Ray, Nicholas R.; Ayodele, Temitope; Jean-Francois, Melissa; Baez, Penelope; Fernandez, Victoria; Bradley, Joseph; Crane, Paul K.; Dalgard, Clifton L.; Kuzma, Amanda; Nicaretta, Heather; Sims, Rebecca; Williams, Julie; Cuccaro, Michael L.; Pericak-Vance, Margaret A.; Mayeux, Richard; Wang, Li-San; Schellenberg, Gerard D.; Cruchaga, Carlos; Beecham, Gary W.; Reitz, Christiane

A genome-wide search for pleiotropy in more than 100,000 harmonized longitudinal cognitive domain scores 在超过100,000个统一的纵向认知域得分中进行全基因组多效性搜索

MOLECULAR NEURODEGENERATION

IF17.5

2023-06-22

OAAI

Kang, Moonil; Ang, Ting Fang Alvin; Devine, Sherral A.; Sherva, Richard; Mukherjee, Shubhabrata; Trittschuh, Emily H.; Gibbons, Laura E.; Scollard, Phoebe; Lee, Michael; Choi, Seo-Eun; Klinedinst, Brandon; Nakano, Connie; Dumitrescu, Logan C.; Durant, Alaina; Hohman, Timothy J.; Cuccaro, Michael L.; Saykin, Andrew J.; Kukull, Walter A.; Bennett, David A.; Wang, Li-San; Mayeux, Richard P.; Haines, Jonathan L.; Pericak-Vance, Margaret A.; Schellenberg, Gerard D.; Crane, Paul K.; Au, Rhoda; Lunetta, Kathryn L.; Mez, Jesse B.; Farrer, Lindsay A.

A haptoglobin (HP) structural variant alters the effect of APOE alleles on Alzheimer's disease 触珠蛋白 (HP) 结构变体改变了APOE等位基因对阿尔茨海默氏病的影响

ALZHEIMERS & DEMENTIA

IF11.1

2023-04-12

OAAI

Bai, Haimeng C.; Naj, Adam; Benchek, Penelope; Dumitrescu, Logan; Hohman, Timothy; Hamilton-Nelson, Kara R.; Kallianpur, Asha J.; Griswold, Anthony; Vardarajan, Badri R.; Martin, Eden W.; Beecham, Gary E.; Below, Jennifer; Schellenberg, Gerard; Mayeux, Richard; Farrer, Lindsay A.; Pericak-Vance, Margaret L.; Haines, Jonathan S.; Bush, William

The role of structural variations in Alzheimer's disease and other neurodegenerative diseases

FRONTIERS IN AGING NEUROSCIENCE

IF4.5

2023-02-08

OAAI

Wang, Hui; Wang, Li-San; Schellenberg, Gerard; Lee, Wan-Ping

Admixture mapping identifies novel Alzheimer's disease risk regions in African Americans

ALZHEIMERS & DEMENTIA

IF11.1

2022-12-20

OAAI

Rajabli, Farid; Tosto, Giuseppe; Hamilton-Nelson, Kara L.; Kunkle, Brian W.; Vardarajan, Badri N.; Naj, Adam; Whitehead, Patrice G.; Gardner, Olivia K.; Bush, William S.; Sariya, Sanjeev; Mayeux, Richard P.; Farrer, Lindsay A.; Cuccaro, Michael L.; Vance, Jeffrey M.; Griswold, Anthony J.; Schellenberg, Gerard D.; Haines, Jonathan L.; Byrd, Goldie S.; Reitz, Christiane; Beecham, Gary W.; Pericak-Vance, Margaret A.; Martin, Eden R.

A locus at 19q13.31 significantly reduces the ApoE ε4 risk for Alzheimer's Disease in African Ancestry

PLOS GENETICS

IF3.7

2022-07-05

OAAI

Rajabli, Farid; Beecham, Gary W.; Hendrie, Hugh C.; Baiyewu, Olusegun; Ogunniyi, Adesola; Gao, Sujuan; Kushch, Nicholas A.; Lipkin-Vasquez, Marina; Hamilton-Nelson, Kara L.; Young, Juan I.; Dykxhoorn, Derek M.; Nuytemans, Karen; Kunkle, Brian W.; Wang, Liyong; Jin, Fulai; Liu, Xiaoxiao; Feliciano-Astacio, Briseida E.; Schellenberg, Gerard D.; Dalgard, Clifton L.; Griswold, Anthony J.; Byrd, Goldie S.; Reitz, Christiane; Cuccaro, Michael L.; Haines, Jonathan L.; Pericak-Vance, Margaret A.; Vance, Jeffery M.

Genome-wide association and multi-omics studies identify MGMT as a novel risk gene for Alzheimer's disease among women 全基因组关联和多组学研究确定MGMT是女性阿尔茨海默病的新风险基因

ALZHEIMERS & DEMENTIA

IF11.1

2022-06-30

OAAI

Chung, Jaeyoon; Das, Anjali; Sun, Xinyu; Sobreira, Debora R.; Leung, Yuk Yee; Igartua, Catherine; Mozaffari, Sahar; Chou, Yi-Fan; Thiagalingam, Sam; Mez, Jesse; Zhang, Xiaoling; Jun, Gyungah R.; Stein, Thor D.; Kunkle, Brian W.; Martin, Eden R.; Pericak-Vance, Margaret A.; Mayeux, Richard; Haines, Jonathan L.; Schellenberg, Gerard D.; Nobrega, Marcelo A.; Lunetta, Kathryn L.; Pinto, Jayant M.; Wang, Li-San; Ober, Carole; Farrer, Lindsay A.

研究方向