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ChREBP-mediated up-regulation of Them1 coordinates thermogenesis with glycolysis and lipogenesis in response to chronic stress Xu, Xu; Mendoza, Arturo; Krumm, Christopher S.; Su, Shi; Acuna, Mariana; Bare, Curtis J.; Holman, Corey D.; Cortopassi, Marissa; Nicholls, Hayley T.; Dartigue, Vincent; Hollenberg, Anthony N.; Lee, Ann-Hwee; Hagen, Susan J.; Cohen, David E. 分享 收藏
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High-throughput screening identifies small molecule inhibitors of thioesterase superfamily member 1: Implications for the management of non-alcoholic fatty liver disease Krumm, Christopher S.; Landzberg, Renee S.; Ramos-Espiritu, Lavoisier; Adura, Carolina; Liu, Xu; Acuna, Mariana; Xie, Yang; Xu, Xu; Tillman, Matthew C.; Li, Yingxia; Glickman, J. Fraser; Ortlund, Eric A.; Ginn, John D.; Cohen, David E. 分享 收藏
Acyl-CoA thioesterase 12 suppresses YAP-mediated hepatocarcinogenesis by limiting glycerolipid biosynthesis He, Haiyue; Sugiyama, Akiko; Snyder, Nathaniel W.; Teneche, Marcos G.; Liu, Xiaowei; Maner-Smith, Kristal M.; Goessling, Wolfram; Hagen, Susan J.; Ortlund, Eric A.; Najafi-Shoushtari, S. Hani; Acuna, Mariana; Cohen, David E. 分享 收藏
Ligand dependent interaction between PC-TP and PPARδ mitigates diet-induced hepatic steatosis in male mice Druzak, Samuel A.; Tardelli, Matteo; Mays, Suzanne G.; El Bejjani, Mireille; Mo, Xulie; Maner-Smith, Kristal M.; Bowen, Thomas; Cato, Michael L.; Tillman, Matthew C.; Sugiyama, Akiko; Xie, Yang; Fu, Haian; Cohen, David E.; Ortlund, Eric A. 分享 收藏
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A beta cell subset with enhanced insulin secretion and glucose metabolism is reduced in type 2 diabetes Rubio-Navarro, Alfonso; Gomez-Banoy, Nicolas; Stoll, Lisa; Dundar, Friederike; Mawla, Alex M.; Ma, Lunkun; Cortada, Eric; Zumbo, Paul; Li, Ang; Reiterer, Moritz; Montoya-Oviedo, Nathalia; Homan, Edwin A.; Imai, Norihiro; Gilani, Ankit; Liu, Chengyang; Naji, Ali; Yang, Boris; Chong, Angie Chi Nok; Cohen, David E.; Chen, Shuibing; Cao, Jingli; Pitt, Geoffrey S.; Huising, Mark O.; Betel, Doron; Lo, James C. C. 分享 收藏
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Human hepatocyte PNPLA3-148M exacerbates rapid non-alcoholic fatty liver disease development in chimeric mice 人肝细胞PNPLA3-148M加剧嵌合小鼠非酒精性脂肪性肝病的快速发展 Kabbani, Mohammad; Michailidis, Eleftherios; Steensels, Sandra; Fulmer, Clifton G.; Luna, Joseph M.; Le Pen, Jeremie; Tardelli, Matteo; Razooky, Brandon; Ricardo-Lax, Inna; Zou, Chenhui; Zeck, Briana; Stenzel, Ansgar F.; Quirk, Corrine; Foquet, Lander; Ashbrook, Alison W.; Schneider, William M.; Belkaya, Serkan; Lalazar, Gadi; Liang, Yupu; Pittman, Meredith; Devisscher, Lindsey; Suemizu, Hirosh; Theise, Neil D.; Chiriboga, Luis; Cohen, David E.; Copenhaver, Robert; Grompe, Markus; Meuleman, Philip; Ersoy, Baran A.; Rice, Charles M.; Jong, Ype P. de 分享 收藏
Blocking ActRIIB and restoring appetite reverses cachexia and improves survival in mice with lung cancer Queiroz, Andre Lima; Dantas, Ezequiel; Ramsamooj, Shakti; Murthy, Anirudh; Ahmed, Mujmmail; Zunica, Elizabeth; Liang, Roger; Murphy, Charles; Holman, Corey; Bare, Curtis; Ghahramani, Gregory; Wu, Zhidan; Cohen, David; Kirwan, John; Cantley, Lewis; Axelrod, Christopher; Goncalves, Marcus 分享 收藏
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Thyroid hormone signaling promotes hepatic lipogenesis through the transcription factor ChREBP Mendoza, Arturo; Tang, Catherine; Choi, Jinyoung; Acuna, Mariana; Logan, Maya; Martin, Adriana G.; Al-Sowaimel, Lujain; Desai, Bhavna N.; Tenen, Danielle E.; Jacobs, Christopher; Lyubetskaya, Anna; Fu, Yulong; Liu, Hong; Tsai, Linus; Cohen, David E.; Forrest, Douglas; Wilson, Andrew A.; Hollenberg, Anthony N. 分享 收藏
The 2020 Nobel Prize for Medicine or Physiology for the Discovery of Hepatitis C Virus: A Triumph of Curiosity and Persistence Ghany, Marc G.; Lok, Anna S. F.; Dienstag, Jules L.; Feinstone, Stephen M.; Hoofnagle, Jay H.; Liang, T. Jake; Seeff, Leonard B.; Cohen, David E.; Bezerra, Jorge A.; Chung, Raymond T. 分享 收藏
Inducible hepatic expression of CREBH mitigates diet-induced obesity, insulin resistance, and hepatic steatosis in mice Krumm, Christopher S.; Xu, Xu; Bare, Curtis J.; Holman, Corey D.; Kersten, Sander; Dow, Lukas E.; Lee, Ann-Hwee; Cohen, David E. 分享 收藏
Thioesterase superfamily member 1 undergoes stimulus-coupled conformational reorganization to regulate metabolism in mice Li, Yue; Imai, Norihiro; Nicholls, Hayley T.; Roberts, Blaine R.; Goyal, Samaksh; Krisko, Tibor I.; Ang, Lay-Hong; Tillman, Matthew C.; Roberts, Anne M.; Baqai, Mahnoor; Ortlund, Eric A.; Cohen, David E.; Hagen, Susan J. 分享 收藏
A human liver chimeric mouse model for non-alcoholic fatty liver disease Bissig-Choisat, Beatrice; Alves-Bezerra, Michele; Zorman, Barry; Ochsner, Scott A.; Barzi, Mercedes; Legras, Xavier; Yang, Diane; Borowiak, Malgorzata; Dean, Adam M.; York, Robert B.; Galvan, N. Thao N.; Goss, John; Lagor, William R.; Moore, David D.; Cohen, David E.; McKenna, Neil J.; Sumazin, Pavel; Bissig, Karl-Dimiter 分享 收藏
Improvement in insulin resistance and estimated hepatic steatosis and fibrosis after endoscopic sleeve gastroplasty Hajifathalian, Kaveh; Mehta, Amit; Ang, Bryan; Skaf, Daniel; Shah, Shawn L.; Saumoy, Monica; Dawod, Qais; Dawod, Enad; Shulda, Alpana; Aronne, Louis; Brown, Robert S.; Cohen, David E.; Dannenberg, Andrew J.; Fortune, Brett; Kumar, Sonal; Sharaiha, Reem Z. 分享 收藏
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