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The Overexpression of Collagen Receptor DDR1 is Associated With Chromosome Instability and Aneuploidy in Diffuse Large B-Cell Lymphoma 弥漫性大B细胞淋巴瘤中胶原受体DDR1的过表达与染色体不稳定性及非整倍体相关 Margielewska-Davies, Sandra; Pugh, Matthew; Nagy, Eszter; Leahy, Ciara I.; Ibrahim, Maha; Fennell, Eanna; Ross, Aisling; Bouchal, Jan; Lupino, Lauren; Care, Matthew; Tooze, Reuben; Reynolds, Gary; Rudzki, Zbigniew; Wei, Wenbin; Simmons, William; Rand, Vikki; Hunter, Kelly; Reynolds, John J.; Stewart, Grant S.; Bouchalova, Katerina; Douglas, Iona J.; Vrzalikova, Katerina; Murray, Paul G. 分享 收藏
PCNA-binding activity separates RNF168 functions in DNA replication and DNA double-stranded break signaling Yang, Yang; Jayaprakash, Deepika; Jhujh, Satpal S.; Reynolds, John J.; Chen, Steve; Gao, Yanzhe; Anand, Jay Ramanlal; Mutter-Rottmayer, Elizabeth; Ariel, Pablo; An, Jing; Cheng, Xing; Pearce, Kenneth H.; Blanchet, Sophie-Anne; Nandakumar, Nandana; Zhou, Pei; Fradet-Turcotte, Amelie; Stewart, Grant S.; Vaziri, Cyrus 分享 收藏
RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells XRN2的RNF8泛素化促进R环解析并抑制BRCA1突变细胞中的基因组不稳定性 Krishnan, Rehna; Lapierre, Mariah; Gautreau, Brandon; Nixon, Kevin C. J.; El Ghamrasni, Samah; Patel, Parasvi S.; Hao, Jun; Yerlici, V. Talya; Guturi, Kiran Kumar Naidu; St-Germain, Jonathan; Mateo, Francesca; Saad, Amine; Algouneh, Arash; Earnshaw, Rebecca; Shili, Duan; Seitova, Alma; Miller, Joshua; Khosraviani, Negin; Penn, Adam; Ho, Brandon; Sanchez, Otto; Hande, M. Prakash; Masson, Jean-Yves; Brown, Grant W.; Alaoui-Jamali, Moulay; Reynolds, John J.; Arrowsmith, Cheryl; Raught, Brian; Pujana, Miguel A.; Mekhail, Karim; Stewart, Grant S.; Hakem, Anne; Hakem, Razqallah 分享 收藏
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Excessive transcription-replication conflicts are a vulnerability of BRCA1-mutant cancers 过度的转录复制冲突是BRCA1-mutant癌症的脆弱性 Patel, Parasvi S.; Algouneh, Arash; Krishnan, Rehna; Reynolds, John J.; Nixon, Kevin C. J.; Hao, Jun; Lee, Jihoon; Feng, Yue; Fozil, Chehronai; Stanic, Mia; Yerlici, Talya; Su, Peiran; Soares, Fraser; Liedtke, Elisabeth; Prive, Gil; Baider, Gary D.; Pujana, Miquel Angel; Mekhail, Karim; He, Housheng Hansen; Hakem, Anne; Stewart, Grant S.; Hakem, Razqallah 分享 收藏
Pathogenic variants in SLF2 and SMC5 cause segmented chromosomes and mosaic variegated hyperploidy Grange, Laura J.; Reynolds, John J.; Ullah, Farid; Isidor, Bertrand; Shearer, Robert F.; Latypova, Xenia; Baxley, Ryan M.; Oliver, Antony W.; Ganesh, Anil; Cooke, Sophie L.; Jhujh, Satpal S.; McNee, Gavin S.; Hollingworth, Robert; Higgs, Martin R.; Natsume, Toyoaki; Khan, Tahir; Martos-Moreno, Gabriel A.; Chupp, Sharon; Mathew, Christopher G.; Parry, David; Simpson, Michael A.; Nahavandi, Nahid; Yuksel, Zafer; Drasdo, Mojgan; Kron, Anja; Vogt, Petra; Jonasson, Annemarie; Seth, Saad Ahmed; Gonzaga-Jauregui, Claudia; Brigatti, Karlla W.; Stegmann, Alexander P. A.; Kanemaki, Masato; Josifova, Dragana; Uchiyama, Yuri; Oh, Yukiko; Morimoto, Akira; Osaka, Hitoshi; Ammous, Zineb; Argente, Jesus; Matsumoto, Naomichi; Stumpel, Constance T. R. M.; Taylor, Alexander M. R.; Jackson, Andrew P.; Bielinsky, Anja-Katrin; Mailand, Niels; Le Caignec, Cedric; Davis, Erica E.; Stewart, Grant S. 分享 收藏
RECON syndrome is a genome instability disorder caused by mutations in the DNA helicase RECQL1 Abu-Libdeh, Bassam; Jhujh, Satpal S.; Dhar, Srijita; Sommers, Joshua A.; Datta, Arindam; Longo, Gabriel M. C.; Grange, Laura J.; Reynolds, John J.; Cooke, Sophie L.; McNee, Gavin S.; Hollingworth, Robert; Woodward, Beth L.; Ganesh, Anil N.; Smerdon, Stephen J.; Nicolae, Claudia M.; Durlacher-Betzer, Karina; Molho-Pessach, Vered; Abu-Libdeh, Abdulsalam; Meiner, Vardiella; Moldovan, George-Lucian; Roukos, Vassilis; Harel, Tamar; Brosh, Robert M., Jr.; Stewart, Grant S. 分享 收藏
DONSON and FANCM associate with different replisomes distinguished by replication timing and chromatin domain Zhang, Jing; Bellani, Marina A.; James, Ryan C.; Pokharel, Durga; Zhang, Yongqing; Reynolds, John J.; McNee, Gavin S.; Jackson, Andrew P.; Stewart, Grant S.; Seidman, Michael M. 分享 收藏
Novel PNKP mutations causing defective DNA strand break repair and PARP1 hyperactivity in MCSZ 新型PNKP突变导致MCSZ中DNA链断裂修复缺陷和PARP1过度活跃 Kalasova, Ilona; Hanzlikova, Hana; Gupta, Neerja; Li, Yun; Altmueller, Janine; Reynolds, John J.; Stewart, Grant S.; Wollnik, Bernd; Yigit, Goekhan; Caldecott, Keith W. 分享 收藏
Bi-allelic Variants in TONSL Cause SPONASTRIME Dysplasia and a Spectrum of Skeletal Dysplasia Phenotypes Burrage, Lindsay C.; Reynolds, John J.; Baratang, Nissan Vida; Phillips, Jennifer B.; Wegner, Jeremy; McFarquhar, Ashley; Higgs, Martin R.; Christiansen, Audrey E.; Lanza, Denise G.; Seavitt, John R.; Jain, Mahim; Li, Xiaohui; Parry, David A.; Raman, Vandana; Chitayat, David; Chinn, Ivan K.; Bertuch, Alison A.; Karaviti, Lefkothea; Schlesinger, Alan E.; Earl, Dawn; Bamshad, Michael; Savarirayan, Ravi; Doddapaneni, Harsha; Muzny, Donna; Jhangiani, Shalini N.; Eng, Christine M.; Gibbs, Richard A.; Bi, Weimin; Emrick, Lisa; Rosenfeld, Jill A.; Postlethwait, John; Westerfield, Monte; Dickinson, Mary E.; Beaudet, Arthur L.; Ranza, Emmanuelle; Huber, Celine; Cormier-Daire, Valerie; Shen, Wei; Mao, Rong; Heaney, Jason D.; Orange, I. Jordan S.; Bertola, Debora; Yamamoto, Guilherme L.; Baratela, Wagner Ar; Butler, Merlin G.; Ali, Asim; Adeli, Mehdi; Cohn, Daniel H.; Krakow, Deborah; Jackson, Andrew P.; Lees, Melissa; Offiah, Amaka C.; Carlston, Colleen M.; Carey, John C.; Stewart, Grant S.; Bacino, Carlos A.; Campeau, Philippe M.; Lee, Brendan 分享 收藏
Analysis of novel missense ATR mutations reveals new splicing defects underlying Seckel syndrome Llorens-Agost, Marta; Luessing, Janna; van Beneden, Amandine; Eykelenboom, John; O'Reilly, Dawn; Bicknell, Louise S.; Reynolds, John J.; van Koegelenberg, Marianne; Hurles, Matthew E.; Brady, Angela F.; Jackson, Andrew P.; Stewart, Grant S.; Lowndes, Noel F. 分享 收藏
Histone Methylation by SETD1A Protects Nascent DNA through the Nucleosome Chaperone Activity of FANCD2 Higgs, Martin R.; Sato, Koichi; Reynolds, John J.; Begum, Shabana; Bayley, Rachel; Goula, Amalia; Vernet, Audrey; Paquin, Karissa L.; Skalnik, David G.; Kobayashi, Wataru; Takata, Minoru; Howlett, Niall G.; Kurumizaka, Hitoshi; Kimura, Hiroshi; Stewart, Grant S. 分享 收藏
Elevated PTTG and PBF predicts poor patient outcome and modulates DNA damage response genes in thyroid cancer Read, M. L.; Fong, J. C.; Modasia, B.; Fletcher, A.; Imruetaicharoenchoke, W.; Thompson, R. J.; Nieto, H.; Reynolds, J. J.; Bacon, A.; Mallick, U.; Hackshaw, A.; Watkinson, J. C.; Boelaert, K.; Turnell, A. S.; Smith, V. E.; McCabe, C. J. 分享 收藏
PRMT5-Dependent Methylation of the TIP60 Coactivator RUVBL1 Is a Key Regulator of Homologous Recombination Clarke, Thomas L.; Sanchez-Bailon, Maria Pilar; Chiang, Kelly; Reynolds, John J.; Herrero-Ruiz, Joaquin; Bandeiras, Tiago M.; Matias, Pedro M.; Maslen, Sarah L.; Skehel, J. Mark; Stewart, Grant S.; Davies, Clare C. 分享 收藏
Mutations in DONSON disrupt replication fork stability and cause microcephalic dwarfism Reynolds, John J.; Bicknell, Louise S.; Carroll, Paula; Higgs, Martin R.; Shaheen, Ranad; Murray, Jennie E.; Papadopoulos, Dimitrios K.; Leitch, Andrea; Murina, Olga; Tarnauskaite, Zygimante; Wessel, Sarah R.; Zlatanou, Anastasia; Vernet, Audrey; von Kriegsheim, Alex; Mottram, Rachel M. A.; Logan, Clare V.; Bye, Hannah; Li, Yun; Brean, Alexander; Maddirevula, Sateesh; Challis, Rachel C.; Skouloudaki, Kassiani; Almoisheer, Agaadir; Alsaif, Hessa S.; Amar, Ariella; Prescott, Natalie J.; Bober, Michael B.; Duker, Angela; Faqeih, Eissa; Seidahmed, Mohammed Zain; Al Tala, Saeed; Alswaid, Abdulrahman; Ahmed, Saleem; Al-Aama, Jumana Yousuf; Altmueller, Janine; Al Balwi, Mohammed; Brady, Angela F.; Chessa, Luciana; Cox, Helen; Fischetto, Rita; Heller, Raoul; Henderson, Bertram D.; Hobson, Emma; Nurnberg, Peter; Percin, E. Ferda; Peron, Angela; Spaccini, Luigina; Quigley, Alan J.; Thakur, Seema; Wise, Carol A.; Yoon, Grace; Alnemer, Maha; Tomancak, Pavel; Yigit, Goekhan; Taylor, A. Malcolm R.; Reijns, Martin A. M.; Simpson, Michael A.; Cortez, David; Alkuraya, Fowzan S.; Mathew, Christopher G.; Jackson, Andrew P.; Stewart, Grant S. 分享 收藏
BOD1L Is Required to Suppress Deleterious Resection of Stressed Replication Forks Higgs, Martin R.; Reynolds, John J.; Winczura, Alicja; Blackford, Andrew N.; Borel, Valerie; Miller, Edward S.; Zlatanou, Anastasia; Nieminuszczy, Jadwiga; Ryan, Ellis L.; Davies, Nicholas J.; Stankovic, Tatjana; Boulton, Simon J.; Niedzwiedz, Wojciech; Stewart, Grant S. 分享 收藏
Autoimmunity to the alpha 3 chain of type IV collagen in glomerulonephritis is triggered by 'autoantigen complementarity' Reynolds, John; Preston, Gloria A.; Pressler, Barrak M.; Hewins, Peter; Brown, Michael; Roth, Aleeza; Alderman, Elizabeth; Bunch, Donna; Jennette, J. Charles; Cook, H. Terence; Falk, Ronald J.; Pusey, Charles D. 分享 收藏
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