Philippe Lory - Publications, H-index & Citations

Philippe Lory

Inserm

46H指数

143论文数

6.4K被引数

收录论文 52

发表时间

An improved electrophysiological cellular assay to unlock the pharmacological modulation of the NALCN channelosome 一种改进的电生理细胞分析方法，用于解锁NALCN通道复合体的药理学调节

BIOMEDICINE & PHARMACOTHERAPY

IF7.5

2026-05-01

OAAI

Nattaya Thongsepee; Alexandra Typou; Romain Baudat; Jeremy A. Tanner; Isabel Del Pino; Donard S. Dwyer; Philippe Lory; Arnaud Monteil

The sodium leak channel NALCN in Drd2+ striatal neurons regulates neuronal excitability, locomotion and food-seeking in a sex-dependent manner 钠泄漏通道NALCN在Drd2+纹状体神经元中调节神经元兴奋性、运动和觅食行为，且具有性别依赖性。

Neuropsychopharmacology

IF7.1

2026-02-11

PREAI

Laia Castell; Claire Naon; Angelina Rogliardo; Fabien Ducrocq; Leila Makrini; Alexandra Typou; Maëlle Avrillon; Audrey Mignon; Claire Bernat; Philippe Lory; Federica Bertaso; Arnaud Monteil; Clémentine Bosch-Bouju; Emmanuel Valjent

Zebrafish fast muscle contractions avoid the mammalian requirement for voltage-gated Na+ channels

PLOS BIOLOGY

IF7.2

2025-11-01

PREAI

Demesmay, Lea; Idoux, Romane; Berthier, Christine; Bernat, Claire; Espinosa, Leon; Jacquemond, Vincent; Brunet, Frederic; Maunier-Mercier, Angel; Lory, Philippe; Nicole, Sophie; Allard, Bruno

Electrophysiological classification of CACNA1G gene variants associated with neurodevelopmental and neurological disorders CACNA1G基因变异与神经发育及神经性疾病的电生理学分类

Frontiers in Pharmacology

IF4.8

2025-10-02

OAAI

Amaël Davakan†; Leos Cmarko†; Barbara Ribeiro Oliveira-Mendes; Claire Bernat; Najlae Boulali; Jérôme Montnach; Stephanie E. Vallee; Mary B. Dinulos; Lydie Burglen; Vincent Cantagrel; Norbert Weiss; Sophie Nicole; Arnaud Monteil; Michel De Waard; Philippe Lory

The characterization of new de novo CACNA1G variants affecting the intracellular gate of Cav3.1 channel broadens the spectrum of neurodevelopmental phenotypes in SCA42ND 新发现的SCA42ND中影响Cav3.1通道细胞内闸门的de novo CACNA1G变异的特征分析，扩展了神经发育表型的谱系。

GENETICS IN MEDICINE

IF6.2

2025-03-01

PREAI

Qebibo, Leila; Davakan, Amael; Nesson-Dauphin, Mathilde; Boulali, Najlae; Siquier-Pernet, Karine; Afenjar, Alexandra; Amiel, Jeanne; Bartholdi, Deborah; Barth, Magalie; Blondiaux, Eleonore; Cristian, Ingrid; Frazier, Zoe; Goldenberg, Alice; Good, Jean-Marc; Salussolia, Catherine Lourdes; Sahin, Mustafa; McCullagh, Helen; McDonald, Kimberly; McRae, Anne; Morrison, Jennifer; Pinner, Jason; Shinawi, Marwan; Toutain, Annick; Vyhnalkova, Emilie; Wheeler, Patricia G.; Wilnai, Yael; Hausman-Kedem, Moran; Coolen, Marion; Cantagrel, Vincent; Burglen, Lydie; Lory, Philippe

Structural basis for human Cav3.2 inhibition by selective antagonists 选择性拮抗剂抑制人Cav3.2的结构基础

CELL RESEARCH

IF25.9

2024-04-11

OAAI

Huang, Jian; Fan, Xiao; Jin, Xueqin; Lyu, Chen; Guo, Qinmeng; Liu, Tao; Chen, Jiaofeng; Davakan, Amael; Lory, Philippe; Yan, Nieng

New insights into the physiology and pathophysiology of the atypical sodium leak channel NALCN

PHYSIOLOGICAL REVIEWS

IF28.7

2024-01-01

OAAI

Monteil, Arnaud; Guerineau, Nathalie C.; Gil-Nagel, Antonio; Parra-Diaz, Paloma; Lory, Philippe; Senatore, Adriano

Sodium background currents in endocrine/neuroendocrine cells: Towards unraveling channel identity and contribution in hormone secretion

FRONTIERS IN NEUROENDOCRINOLOGY

IF6.7

2021-10-01

OAAI

Guerineau, Nathalie C.; Monteil, Arnaud; Lory, Philippe

The sodium leak channel NALCN regulates cell excitability of pituitary endocrine cells

FASEB JOURNAL

IF4.2

2021-04-01

OAAI

Impheng, Hathaichanok; Lemmers, Celine; Bouasse, Malik; Legros, Christian; Pakaprot, Narawut; Guerineau, Nathalie C.; Lory, Philippe; Monteil, Arnaud

A novel phospho-modulatory mechanism contributes to the calcium-dependent regulation of T-type Ca2+ channels

SCIENTIFIC REPORTS

IF3.9

2019-10-30

OAAI

Chemin, Jean; Stamenic, Tamara Timic; Cazade, Magalie; Llinares, Jodie; Blesneac, Iulia; Todorovic, Slobodan M.; Lory, Philippe

Functional expression of CLIFAHDD and IHPRF pathogenic variants of the NALCN channel in neuronal cells reveals both gain- and loss-of-function properties

SCIENTIFIC REPORTS

IF3.9

2019-08-13

OAAI

Bouasse, Malik; Impheng, Hathaichanok; Servant, Zoe; Lory, Philippe; Monteil, Arnaud

Lysosomal and network alterations in human mucopolysaccharidosis type VII iPSC-derived neurons

SCIENTIFIC REPORTS

IF3.9

2018-11-09

OAAI

Bayo-Puxan, Neus; Terrasso, Ana Paula; Creyssels, Sophie; Simao, Daniel; Begon-Pescia, Christina; Lavigne, Marina; Salinas, Sara; Bernex, Florence; Bosch, Assumpcio; Kalatzis, Vasiliki; Levade, Thierry; Cuervo, Ana Maria; Lory, Philippe; Consiglio, Antonella; Brito, Catarina; Kremer, Eric J.

De novo mutation screening in childhood-onset cerebellar atrophy identifies gain-of-function mutations in the CACNA1G calcium channel gene

BRAIN

IF11.7

2018-06-05

OAAI

Chemin, Jean; Siquier-Pernet, Karine; Nicouleau, Michaeel; Barcia, Giulia; Ahmad, Ali; Medina-Cano, Daniel; Hanein, Sylvain; Altin, Nami; Hubert, Laurence; Bole-Feysot, Christine; Fourage, Cecile; Nitschke, Patrick; Thevenon, Julien; Rio, Marlene; Blanc, Pierre; Vidal, Celine; Bahi-Buisson, Nadia; Desguerre, Isabelle; Munnich, Arnold; Lyonnet, Stanislas; Boddaert, Nathalie; Fassi, Emily; Shinawi, Marwan; Zimmerman, Holly; Amiel, Jeanne; Faivre, Laurence; Colleaux, Laurence; Lory, Philippe; Cantagrel, Vincent

Characterization of the dominant inheritance mechanism of Episodic Ataxia type 2

NEUROBIOLOGY OF DISEASE

IF5.6

2017-10-01

PREAI

Dorgans, Kevin; Salvi, Julie; Bertaso, Federica; Bernard, Ludivine; Lory, Philippe; Doussau, Frederic; Mezghrani, Alexandre

T-type voltage gated calcium channels are involved in endothelium-dependent relaxation of mice pulmonary artery

BIOCHEMICAL PHARMACOLOGY

IF5.6

2017-08-01

PREAI

Gilbert, Guillaume; Courtois, Arnaud; Dubois, Mathilde; Cussac, Laure-Anne; Ducret, Thomas; Lory, Philippe; Marthan, Roger; Savineau, Jean-Pierre; Quignard, Jean-Francois

Activity-dependent regulation of T-type calcium channels by submembrane calcium ions

ELIFE

IF0

2017-01-21

OAAI

Cazade, Magali; Bidaud, Isabelle; Lory, Philippe; Chemin, Jean

CACNA1H Mutations Are Associated With Different Forms of Primary Aldosteronism CACNA1H突变与不同形式的原发性醛固酮增多症相关

EBIOMEDICINE

IF10.8

2016-11-01

111

OAAI

Daniil, Georgios; Fernandes-Rosa, Fabio L.; Chemin, Jean; Blesneac, Iulia; Beltrand, Jacques; Polak, Michel; Jeunemaitre, Xavier; Boulkroun, Sheerazed; Amar, Laurence; Strom, Tim M.; Lory, Philippe; Zennaro, Maria-Christina

CACNA1H MUTATIONS ARE ASSOCIATED WITH YOUNG ONSET AND FAMILIAL FORMS OF PRIMARY ALDOSTERONISM CACNA1H突变与原发性醛固酮增多症的年轻发作和家族性形式有关

JOURNAL OF HYPERTENSION

IF4.1

2016-09-01

PREAI

Daniil, G.; Fernandes-Rosa, F. L.; Chemin, J.; Jeunemaitre, X.; Polak, M.; Boulkroun, S.; Amar, L.; Strom, T. M.; Lory, P.; Zennaro, M. C.

A Recurrent Mutation in CACNA1G Alters Cav3.1 T-Type Calcium-Channel Conduction and Causes Autosomal-Dominant Cerebellar Ataxia

AMERICAN JOURNAL OF HUMAN GENETICS

IF8.1

2015-11-01

OAAI

Coutelier, Marie; Blesneac, Iulia; Monteil, Arnaud; Monin, Marie-Lorraine; Ando, Kunie; Mundwiller, Emeline; Brusco, Alfredo; Le Ber, Isabelle; Anheim, Mathieu; Castrioto, Anna; Duyckaerts, Charles; Brice, Alexis; Durr, Alexandra; Lory, Philippe; Stevanin, Giovanni

Phosphorylation of the Cav3.2 T-type calcium channel directly regulates its gating properties Cav3.2 T型钙通道的磷酸化直接调节其门控特性

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IF9.1

2015-10-19

OAAI

Blesneac, Iulia; Chemin, Jean; Bidaud, Isabelle; Huc-Brandt, Sylvaine; Vandermoere, Franck; Lory, Philippe

研究方向